DK491582A - Fremgangsmaade til fremstilling af morphinanderivater - Google Patents
Fremgangsmaade til fremstilling af morphinanderivater Download PDFInfo
- Publication number
- DK491582A DK491582A DK491582A DK491582A DK491582A DK 491582 A DK491582 A DK 491582A DK 491582 A DK491582 A DK 491582A DK 491582 A DK491582 A DK 491582A DK 491582 A DK491582 A DK 491582A
- Authority
- DK
- Denmark
- Prior art keywords
- morphinand
- derivatives
- procedure
- preparation
- morphinand derivatives
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
- C07D405/04—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/04—Centrally acting analgesics, e.g. opioids
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D221/00—Heterocyclic compounds containing six-membered rings having one nitrogen atom as the only ring hetero atom, not provided for by groups C07D211/00 - C07D219/00
- C07D221/02—Heterocyclic compounds containing six-membered rings having one nitrogen atom as the only ring hetero atom, not provided for by groups C07D211/00 - C07D219/00 condensed with carbocyclic rings or ring systems
- C07D221/22—Bridged ring systems
- C07D221/28—Morphinans
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
- C07D405/06—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pain & Pain Management (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Biomedical Technology (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Other In-Based Heterocyclic Compounds (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US06/319,482 US4374139A (en) | 1981-11-09 | 1981-11-09 | Levorotatory N-substituted acylmorphinans useful as analgesic agents |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| DK491582A true DK491582A (da) | 1983-05-10 |
Family
ID=23242421
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DK491582A DK491582A (da) | 1981-11-09 | 1982-11-05 | Fremgangsmaade til fremstilling af morphinanderivater |
Country Status (18)
| Country | Link |
|---|---|
| US (1) | US4374139A (fr) |
| EP (1) | EP0079556A3 (fr) |
| JP (1) | JPS5888364A (fr) |
| KR (1) | KR840002357A (fr) |
| AU (1) | AU9027682A (fr) |
| CA (1) | CA1195324A (fr) |
| DK (1) | DK491582A (fr) |
| ES (2) | ES517222A0 (fr) |
| FI (1) | FI823824L (fr) |
| GR (1) | GR78317B (fr) |
| HU (1) | HU187425B (fr) |
| IL (1) | IL67180A0 (fr) |
| MC (1) | MC1490A1 (fr) |
| NO (1) | NO823707L (fr) |
| NZ (1) | NZ202404A (fr) |
| PH (1) | PH18458A (fr) |
| PT (1) | PT75815B (fr) |
| ZA (1) | ZA827905B (fr) |
Families Citing this family (21)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4423221A (en) * | 1982-06-10 | 1983-12-27 | Sisa Pharmaceutical Laboratories, Inc. | 7-Carboethoxy-morphinan-6-one compounds |
| US4454141A (en) * | 1982-09-23 | 1984-06-12 | Sisa Pharmaceutical Laboratories, Inc. | Trans-B/C-7-(1-hydroxypentyl)-3-methoxy-17 methyl-6,7-didehydromorphinans, and methods of relieving pain with them |
| EP0184041A1 (fr) * | 1984-11-13 | 1986-06-11 | Miles Inc. | Purification de 6-méthylène-morphinanes |
| US4929622A (en) * | 1987-09-24 | 1990-05-29 | Hoechst-Roussel Pharmaceuticals, Inc. | 2,6-Methanopyrrolo-3-benzazocines |
| DE4304450A1 (de) * | 1993-02-13 | 1994-08-18 | Boehringer Mannheim Gmbh | System zur Zubereitung von Flüssigkeiten |
| EP1353909B1 (fr) * | 2000-10-31 | 2005-04-06 | Rensselaer Polytechnic Institute | 8-carboxamido-2,6-methano-3-benzazocines |
| DE60234057D1 (de) | 2001-07-25 | 2009-11-26 | Raptor Pharmaceutical Inc | Zusammensetzungen und verfahren zur modulation des transports durch die blut-hirn-schranke |
| US20040204862A1 (en) * | 2003-04-11 | 2004-10-14 | Wainer Irving W. | Computer-based model for identification and characterization for non-competitive inhibitors of nicotinic acetylcholine receptors and related ligand-gated ion channel receptors |
| CN103259027A (zh) | 2005-04-28 | 2013-08-21 | 普罗透斯数字保健公司 | 药物信息系统 |
| KR20090071598A (ko) | 2006-09-18 | 2009-07-01 | 랩터 파마슈티컬 인코포레이티드 | 수용체 결합 단백질(ｒａｐ)-접합체 투여에 의한 간 질환의 치료 |
| PT2398500T (pt) | 2009-02-20 | 2019-06-14 | 2 Bbb Medicines B V | Sistema de entrega de medicamentos à base de glutationas |
| TWI556839B (zh) | 2009-05-06 | 2016-11-11 | 研究室護膚股份有限公司 | 包含活性劑－磷酸鈣粒子複合物之皮膚遞送組成物及其使用方法 |
| HUE043963T2 (hu) | 2009-12-04 | 2019-09-30 | Alkermes Pharma Ireland Ltd | Morfinán származékok gyógyszer-túladagolás kezelésére |
| AU2011232628B2 (en) | 2010-03-22 | 2015-04-09 | Rensselaer Polytechnic Institute | Morphinane derivatives containing a carboxamide group as opioid receptor ligands |
| US20120077778A1 (en) | 2010-09-29 | 2012-03-29 | Andrea Bourdelais | Ladder-Frame Polyether Conjugates |
| SI2725908T1 (sl) | 2011-06-29 | 2017-10-30 | Alkermes, Inc. | Periferno delujoče opioidne spojine |
| US9211293B2 (en) | 2011-12-15 | 2015-12-15 | Alkermes Pharma Ireland Limited | Opioid agonist antagonist combinations |
| EP3004114B1 (fr) | 2013-05-24 | 2019-12-25 | Alkermes Pharma Ireland Limited | Analogues de morphane et morphinane, et procédés d'utilisation |
| EP3003311A2 (fr) | 2013-05-24 | 2016-04-13 | Alkermes Pharma Ireland Limited | Méthodes de traitement de symptômes de la dépression |
| WO2018125716A1 (fr) * | 2017-01-02 | 2018-07-05 | Purdue Pharma L.P. | Dérivés de morphinane et leur utilisation |
| EP4243768A1 (fr) | 2020-11-12 | 2023-09-20 | Alkermes Pharma Ireland Limited | Comprimé multicouche à libération immédiate |
Family Cites Families (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3723437A (en) * | 1970-09-15 | 1973-03-27 | American Home Prod | 4,10-(methaniminomethano phenanthrene derivatives |
| ZA73988B (en) * | 1972-03-10 | 1973-10-31 | Hoffmann La Roche | Morphinan derivatives |
| US3914233A (en) * | 1972-10-20 | 1975-10-21 | Hoffmann La Roche | 4-Hydroxy-N-substituted morphinan derivatives |
-
1981
- 1981-11-09 US US06/319,482 patent/US4374139A/en not_active Expired - Fee Related
- 1981-12-29 GR GR69729A patent/GR78317B/el unknown
-
1982
- 1982-10-28 ZA ZA827905A patent/ZA827905B/xx unknown
- 1982-11-05 NZ NZ202404A patent/NZ202404A/en unknown
- 1982-11-05 IL IL67180A patent/IL67180A0/xx unknown
- 1982-11-05 DK DK491582A patent/DK491582A/da not_active Application Discontinuation
- 1982-11-08 NO NO823707A patent/NO823707L/no unknown
- 1982-11-08 EP EP82110285A patent/EP0079556A3/fr not_active Ceased
- 1982-11-08 PT PT75815A patent/PT75815B/pt unknown
- 1982-11-08 FI FI823824A patent/FI823824L/fi not_active Application Discontinuation
- 1982-11-08 HU HU823578A patent/HU187425B/hu unknown
- 1982-11-08 MC MC821609A patent/MC1490A1/fr unknown
- 1982-11-08 CA CA000415102A patent/CA1195324A/fr not_active Expired
- 1982-11-08 PH PH28105A patent/PH18458A/en unknown
- 1982-11-08 JP JP57194799A patent/JPS5888364A/ja active Pending
- 1982-11-08 ES ES517222A patent/ES517222A0/es active Granted
- 1982-11-09 AU AU90276/82A patent/AU9027682A/en not_active Abandoned
- 1982-11-09 KR KR1019820005066A patent/KR840002357A/ko unknown
-
1984
- 1984-02-01 ES ES529349A patent/ES8506635A1/es not_active Expired
Also Published As
| Publication number | Publication date |
|---|---|
| MC1490A1 (fr) | 1983-09-12 |
| NO823707L (no) | 1983-05-10 |
| FI823824A0 (fi) | 1982-11-08 |
| PT75815B (en) | 1986-01-21 |
| AU9027682A (en) | 1983-05-19 |
| ES529349A0 (es) | 1985-08-01 |
| GR78317B (fr) | 1984-09-26 |
| EP0079556A2 (fr) | 1983-05-25 |
| NZ202404A (en) | 1985-11-08 |
| PT75815A (en) | 1982-12-01 |
| ES8500948A1 (es) | 1984-12-01 |
| ZA827905B (en) | 1983-08-31 |
| IL67180A0 (en) | 1983-03-31 |
| JPS5888364A (ja) | 1983-05-26 |
| HU187425B (en) | 1986-01-28 |
| ES8506635A1 (es) | 1985-08-01 |
| KR840002357A (ko) | 1984-06-25 |
| PH18458A (en) | 1985-07-18 |
| FI823824L (fi) | 1983-05-10 |
| EP0079556A3 (fr) | 1983-08-24 |
| US4374139A (en) | 1983-02-15 |
| CA1195324A (fr) | 1985-10-15 |
| ES517222A0 (es) | 1984-12-01 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| AHB | Application shelved due to non-payment |