DK491489A - Imidazolinderivater samt fremgangsmaade til fremstilling deraf - Google Patents

Imidazolinderivater samt fremgangsmaade til fremstilling deraf Download PDF

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Publication number
DK491489A
DK491489A DK491489A DK491489A DK491489A DK 491489 A DK491489 A DK 491489A DK 491489 A DK491489 A DK 491489A DK 491489 A DK491489 A DK 491489A DK 491489 A DK491489 A DK 491489A
Authority
DK
Denmark
Prior art keywords
procedures
preparing
imidazoline derivatives
group
erythemathodes
Prior art date
Application number
DK491489A
Other languages
Danish (da)
English (en)
Other versions
DK491489D0 (da
Inventor
Kazuo Matsumoto
Mamoru Suzuki
Kozo Yamamoto
Isao Takata
Yoshio Iwasawa
Original Assignee
Tanabe Seiyaku Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Tanabe Seiyaku Co filed Critical Tanabe Seiyaku Co
Publication of DK491489D0 publication Critical patent/DK491489D0/da
Publication of DK491489A publication Critical patent/DK491489A/da

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Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D233/00Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
    • C07D233/04Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
    • C07D233/20Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with substituted hydrocarbon radicals, directly attached to ring carbon atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D233/00Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
    • C07D233/54Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
    • C07D233/64Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with substituted hydrocarbon radicals attached to ring carbon atoms, e.g. histidine
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D401/00Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/04Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings directly linked by a ring-member-to-ring-member bond

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Immunology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Saccharide Compounds (AREA)
DK491489A 1988-10-06 1989-10-05 Imidazolinderivater samt fremgangsmaade til fremstilling deraf DK491489A (da)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP63253391A JPH02101065A (ja) 1988-10-06 1988-10-06 イミダゾリン誘導体及びその製法

Publications (2)

Publication Number Publication Date
DK491489D0 DK491489D0 (da) 1989-10-05
DK491489A true DK491489A (da) 1990-04-07

Family

ID=17250719

Family Applications (1)

Application Number Title Priority Date Filing Date
DK491489A DK491489A (da) 1988-10-06 1989-10-05 Imidazolinderivater samt fremgangsmaade til fremstilling deraf

Country Status (17)

Country Link
US (1) US5051441A (ko)
EP (1) EP0363061B1 (ko)
JP (1) JPH02101065A (ko)
KR (1) KR960009570B1 (ko)
CN (1) CN1020096C (ko)
AT (1) ATE78470T1 (ko)
AU (1) AU611827B2 (ko)
CA (1) CA1330997C (ko)
DE (1) DE68902209T2 (ko)
DK (1) DK491489A (ko)
ES (1) ES2052015T3 (ko)
FI (1) FI94632C (ko)
GR (1) GR3005779T3 (ko)
HK (1) HK143095A (ko)
HU (1) HU202211B (ko)
IE (1) IE61924B1 (ko)
IL (1) IL91704A0 (ko)

Families Citing this family (20)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FI91159C (fi) * 1988-12-07 1994-05-25 Tanabe Seiyaku Co Menetelmä imidatsolipitoisten peptidien ja niiden farmaseuttisesti sopivien suolojen valmistamiseksi
GB9020889D0 (en) * 1990-09-25 1990-11-07 May & Baker Ltd New compositions of matter
JP2564380Y2 (ja) * 1993-12-10 1998-03-09 大阪瓦斯株式会社 締付トルク確認継手
DE19540027A1 (de) * 1995-10-27 1997-04-30 Gruenenthal Gmbh Substituierte Imidazolidin-2,4-dion-Verbindungen als pharmazeutische Wirkstoffe
KR100426204B1 (ko) * 1998-05-23 2004-06-24 문승자 합성수지판제조방법
US6365616B1 (en) 1998-08-31 2002-04-02 Sentron Medical, Inc. Methimazole derivatives and tautomeric cyclic thiones to treat autoimmune diseases
US20020142974A1 (en) * 1998-09-11 2002-10-03 Leonard D. Kohn Immune activation by double-stranded polynucleotides
DE60227108D1 (de) * 2001-12-18 2008-07-24 Hoffmann La Roche Cis-imidazoline als mdm2-hemmer
US7425638B2 (en) 2003-06-17 2008-09-16 Hoffmann-La Roche Inc. Cis-imidazolines
CN100562316C (zh) * 2003-06-17 2009-11-25 霍夫曼-拉罗奇有限公司 作为mdm2抑制剂的顺式咪唑啉
US7132421B2 (en) 2003-06-17 2006-11-07 Hoffmann-La Roche Inc. CIS-imidazoles
KR20080027969A (ko) 2004-05-18 2008-03-28 에프. 호프만-라 로슈 아게 신규 cis-이미다졸린
US7893278B2 (en) 2004-06-17 2011-02-22 Hoffman-La Roche Inc. CIS-imidazolines
US20110104186A1 (en) 2004-06-24 2011-05-05 Nicholas Valiante Small molecule immunopotentiators and assays for their detection
EP2130822A1 (en) 2005-12-01 2009-12-09 F. Hoffmann-La Roche AG 2,4,5-triphenyl imidazoline derivatives as inhibitors of the interaction between p53 and mdm2 proteins for use as anticancer agents
KR101015073B1 (ko) 2006-01-18 2011-02-16 에프. 호프만-라 로슈 아게 Mdm2 억제제로서의시스-4,5-비아릴-2-헤테로시클릭-이미다졸린
US7625895B2 (en) 2007-04-12 2009-12-01 Hoffmann-Le Roche Inc. Diphenyl-dihydro-imidazopyridinones
US8252942B2 (en) * 2007-10-09 2012-08-28 Board Of Trustees Of Michigan State University Substituted imidazoline compounds
EP2325180A1 (en) 2007-10-09 2011-05-25 F. Hoffmann-La Roche AG Chiral CIS-imidazolines
JP6447496B2 (ja) * 2014-01-29 2019-01-09 東レ株式会社 多発性硬化症の治療剤又は予防剤

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CH44279A (fr) * 1908-03-09 1909-07-16 Anonima Per Frigorigeni E Moto Appareil pour l'échange de chaleur entre des fluides sous pression
BE635804A (ko) * 1962-03-21
GB1047569A (en) * 1962-10-31 1966-11-09 Du Pont Light-sensitive compositions
US3707475A (en) * 1970-11-16 1972-12-26 Pfizer Antiinflammatory imidazoles
EP0005219B1 (en) * 1978-04-24 1981-07-22 A/S Dumex (Dumex Ltd.) Arylimidazoles, their synthesis and pharmaceutical or veterinary preparations containing them
US4424229A (en) * 1979-04-23 1984-01-03 A/S Dumex (Dumex Ltd.) Fluorine containing 2,4,5-triphenylimidazoles
US4252887A (en) * 1979-08-14 1981-02-24 E. I. Du Pont De Nemours And Company Dimers derived from unsymmetrical 2,4,5-triphenylimidazole compounds as photoinitiators
DE3141063A1 (de) * 1981-10-13 1983-04-28 Schering Ag, 1000 Berlin Und 4619 Bergkamen Neue imidazol-derivate, verfahren zu ihrer herstellung und diese enthaltende pharmazeutische praeparate
GB8906198D0 (en) * 1989-03-17 1989-05-04 Ciba Geigy Ag Compounds

Also Published As

Publication number Publication date
HUT51601A (en) 1990-05-28
CA1330997C (en) 1994-07-26
CN1020096C (zh) 1993-03-17
ATE78470T1 (de) 1992-08-15
IL91704A0 (en) 1990-06-10
CN1041760A (zh) 1990-05-02
HK143095A (en) 1995-09-15
KR960009570B1 (ko) 1996-07-20
DE68902209T2 (de) 1992-12-10
JPH02101065A (ja) 1990-04-12
DK491489D0 (da) 1989-10-05
KR900006296A (ko) 1990-05-07
FI894693A (fi) 1990-04-07
AU611827B2 (en) 1991-06-20
FI94632C (fi) 1995-10-10
ES2052015T3 (es) 1994-07-01
GR3005779T3 (ko) 1993-06-07
AU4236889A (en) 1990-04-12
EP0363061A1 (en) 1990-04-11
HU895226D0 (en) 1990-01-28
JPH0581592B2 (ko) 1993-11-15
FI94632B (fi) 1995-06-30
IE892977L (en) 1990-04-06
EP0363061B1 (en) 1992-07-22
FI894693A0 (fi) 1989-10-04
US5051441A (en) 1991-09-24
HU202211B (en) 1991-02-28
DE68902209D1 (de) 1992-08-27
IE61924B1 (en) 1994-11-30

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Legal Events

Date Code Title Description
AHB Application shelved due to non-payment