DK457181A - Fremgangsmaade til fremstilling af 2-substituerede 4-(4-imidazolyl) pyridin-forbindeslser eller farmaceutisk acceptable syreadditionssalte deraf - Google Patents
Fremgangsmaade til fremstilling af 2-substituerede 4-(4-imidazolyl) pyridin-forbindeslser eller farmaceutisk acceptable syreadditionssalte derafInfo
- Publication number
- DK457181A DK457181A DK457181A DK457181A DK457181A DK 457181 A DK457181 A DK 457181A DK 457181 A DK457181 A DK 457181A DK 457181 A DK457181 A DK 457181A DK 457181 A DK457181 A DK 457181A
- Authority
- DK
- Denmark
- Prior art keywords
- imidazolyl
- substituted
- preparing
- acid addition
- addition salts
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
- C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
- C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D213/24—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with substituted hydrocarbon radicals attached to ring carbon atoms
- C07D213/44—Radicals substituted by doubly-bound oxygen, sulfur, or nitrogen atoms, or by two such atoms singly-bound to the same carbon atom
- C07D213/53—Nitrogen atoms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
- C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
- C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D213/24—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with substituted hydrocarbon radicals attached to ring carbon atoms
- C07D213/44—Radicals substituted by doubly-bound oxygen, sulfur, or nitrogen atoms, or by two such atoms singly-bound to the same carbon atom
- C07D213/46—Oxygen atoms
- C07D213/51—Acetal radicals
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
- C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
- C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D213/61—Halogen atoms or nitro radicals
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
- C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
- C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D213/72—Nitrogen atoms
- C07D213/73—Unsubstituted amino or imino radicals
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
- C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
- C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D213/72—Nitrogen atoms
- C07D213/74—Amino or imino radicals substituted by hydrocarbon or substituted hydrocarbon radicals
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
- C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
- C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D213/78—Carbon atoms having three bonds to hetero atoms, with at the most one bond to halogen, e.g. ester or nitrile radicals
- C07D213/84—Nitriles
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pharmacology & Pharmacy (AREA)
- Engineering & Computer Science (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Pyridine Compounds (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US06/197,388 US4302464A (en) | 1980-10-16 | 1980-10-16 | Imidazolylpyridine therapeutic agents |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| DK457181A true DK457181A (da) | 1982-04-17 |
Family
ID=22729208
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DK457181A DK457181A (da) | 1980-10-16 | 1981-10-15 | Fremgangsmaade til fremstilling af 2-substituerede 4-(4-imidazolyl) pyridin-forbindeslser eller farmaceutisk acceptable syreadditionssalte deraf |
Country Status (18)
| Country | Link |
|---|---|
| US (1) | US4302464A (el) |
| EP (1) | EP0051371B1 (el) |
| JP (1) | JPS5795983A (el) |
| KR (1) | KR850001226B1 (el) |
| AR (3) | AR227941A1 (el) |
| AT (1) | ATE9156T1 (el) |
| AU (1) | AU524257B2 (el) |
| CA (1) | CA1175435A (el) |
| DE (1) | DE3165786D1 (el) |
| DK (1) | DK457181A (el) |
| ES (3) | ES8301229A1 (el) |
| FI (1) | FI72974C (el) |
| GR (1) | GR75096B (el) |
| IE (1) | IE51683B1 (el) |
| IL (1) | IL64054A (el) |
| PH (1) | PH16715A (el) |
| PT (1) | PT73835B (el) |
| YU (3) | YU42734B (el) |
Families Citing this family (12)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4463005A (en) * | 1981-03-18 | 1984-07-31 | Imperial Chemical Industries Plc | Bicyclic guanidines |
| US4510151A (en) * | 1984-02-10 | 1985-04-09 | Usv Pharmaceutical Corporation | Pyridinylimidazole pharmaceutical composition |
| SE8405588D0 (sv) * | 1984-11-08 | 1984-11-08 | Haessle Ab | New compounds |
| DK337086A (da) * | 1985-08-12 | 1987-02-13 | Hoffmann La Roche | Benzimidazolderivater |
| US4911753A (en) * | 1987-01-21 | 1990-03-27 | American Cyanamid Company | Herbicidal 2-(2-imidazolin-2-yl)fluoroalkoxy-, alkenyloxy-, and alkynyloxypyridines and quinolines |
| FR2780973B1 (fr) * | 1998-07-09 | 2001-10-05 | Hoechst Marion Roussel Inc | Procede de preparation du 4-(3-pyridinyl)-1h-imidazole, et les intermediaires mis en oeuvre |
| AR039241A1 (es) | 2002-04-04 | 2005-02-16 | Biogen Inc | Heteroarilos trisustituidos y metodos para su produccion y uso de los mismos |
| UA80296C2 (en) * | 2002-09-06 | 2007-09-10 | Biogen Inc | Imidazolopyridines and methods of making and using the same |
| UA80295C2 (en) | 2002-09-06 | 2007-09-10 | Biogen Inc | Pyrazolopyridines and using the same |
| CL2004000234A1 (es) * | 2003-02-12 | 2005-04-15 | Biogen Idec Inc | Compuestos derivados 3-(piridin-2-il)-4-heteroaril-pirazol sustituidos, antagonistas de aik5 y/o aik4; composicion farmaceutica y uso del compuesto en el tratamiento de desordenes fibroticos como esclerodermia, lupus nefritico, cicatrizacion de herid |
| KR100914375B1 (ko) * | 2007-06-26 | 2009-08-28 | 한국원자력연구원 | 초음파를 이용한 균열 간극의 크기 산출방법 |
| EP4196793A1 (en) | 2020-08-11 | 2023-06-21 | Université de Strasbourg | H2 blockers targeting liver macrophages for the prevention and treatment of liver disease and cancer |
Family Cites Families (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS5343958B2 (el) * | 1972-07-29 | 1978-11-24 |
-
1980
- 1980-10-16 US US06/197,388 patent/US4302464A/en not_active Expired - Lifetime
-
1981
- 1981-10-13 JP JP56163371A patent/JPS5795983A/ja active Granted
- 1981-10-13 DE DE8181304754T patent/DE3165786D1/de not_active Expired
- 1981-10-13 GR GR66265A patent/GR75096B/el unknown
- 1981-10-13 EP EP81304754A patent/EP0051371B1/en not_active Expired
- 1981-10-13 AT AT81304754T patent/ATE9156T1/de not_active IP Right Cessation
- 1981-10-13 AR AR287072A patent/AR227941A1/es active
- 1981-10-14 IE IE2411/81A patent/IE51683B1/en unknown
- 1981-10-15 ES ES506281A patent/ES8301229A1/es not_active Expired
- 1981-10-15 YU YU2471/81A patent/YU42734B/xx unknown
- 1981-10-15 DK DK457181A patent/DK457181A/da not_active Application Discontinuation
- 1981-10-15 FI FI813214A patent/FI72974C/fi not_active IP Right Cessation
- 1981-10-15 AU AU76390/81A patent/AU524257B2/en not_active Ceased
- 1981-10-15 IL IL64054A patent/IL64054A/xx unknown
- 1981-10-15 CA CA000387974A patent/CA1175435A/en not_active Expired
- 1981-10-15 PH PH26350A patent/PH16715A/en unknown
- 1981-10-16 PT PT73835A patent/PT73835B/pt unknown
- 1981-10-16 KR KR1019810003955A patent/KR850001226B1/ko active
-
1982
- 1982-08-25 ES ES515244A patent/ES8306742A1/es not_active Expired
- 1982-08-25 ES ES515243A patent/ES8306741A1/es not_active Expired
- 1982-09-09 AR AR290585A patent/AR228678A1/es active
- 1982-09-09 AR AR290584A patent/AR228677A1/es active
-
1983
- 1983-08-22 YU YU1725/83A patent/YU42877B/xx unknown
- 1983-08-22 YU YU1724/83A patent/YU42876B/xx unknown
Also Published As
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| DK74282A (da) | Fremgangsmaade til fremstilling af imidazodiazepiner eller farmaceutisk acceptable syreadditionssalte deraf | |
| DK160099C (da) | Analogifremgangsmaade til fremstilling af optisk aktive eller racemiske 6-substituerede 2-penem-3-carboxylsyreforbindelser eller farmaceutisk anvendelige salte deraf | |
| DK160940C (da) | Analogifremgangsmaade til fremstilling af benzoheterocycliske forbindelser eller farmaceutisk acceptable salte deraf | |
| DK150510C (da) | Analogifremgangsmaade til fremstilling af substituerede 2-(2-benzimidazolyl)-pyridiner eller terapeutisk acceptable salte deraf | |
| DK217481A (da) | Fremgangsmaade til fremstilling af pyridoxinderivater eller syreadditionssalte deraf | |
| DK405881A (da) | Fremgangsmaade til fremstilling af 7beta-aminothiadiazolylacetylamino3-ammoniomethyl-3-cephem-4-carboxylsyreforbindelser eller salte deraf | |
| DK148795C (da) | Anologifremgangsmaade til fremstilling af 3-(2-morpholino-ethyl-amino)-5-phenyl-pyridazin eller farmaceutisk acceptable syreadditionssalte deraf | |
| DK149569C (da) | Analogifremgangsmaade til fremstilling af isoquinolineddikesyre-forbindelser eller farmaceutisk acceptable salte deraf | |
| DK457181A (da) | Fremgangsmaade til fremstilling af 2-substituerede 4-(4-imidazolyl) pyridin-forbindeslser eller farmaceutisk acceptable syreadditionssalte deraf | |
| DK405981A (da) | Fremgangsmaade til fremstilling af n-oxider af n-oxacyclylalkylpiperidyl-diazaforbindelser eller syreadditionssalte deraf | |
| DK413783D0 (da) | Fremgangsmade til fremstilling af 20-amino-macrolidderivater eller syreadditionssalte deraf | |
| DK334581A (da) | Fremgangsmaade til frmstilling af 9-amino-1-hydroxyotahydro-6h-benzo (c) quinolin-derivater eller syreadditionssalte deraf | |
| DK453181A (da) | Fremgangsmaade til fremstilling af 2-quanidino-4-heteroaryl-thiazolforbindelser eller syreadditionssalte deraf | |
| DK29381A (da) | Fremgangsmaade til fremstilling af 1-(cyclohexy)-4-aryl-4-piperidincarboxylsyrederivater | |
| DK162166C (da) | Analogifremgangsmaade til fremstilling af (2s)-isomere af 2-oe4-(2-hydroxycyclopentan-1-ylmethyl)phenylaapropionsyre eller farmaceutisk acceptable salte deraf | |
| DK154647C (da) | Analogifremgangsmaade til fremstilling af n-oe(4-oe3-substitueret 2-pyridylaapiperazino)butylaaazaspirodecanforbindelser eller et farmaceutisk acceptabelt syreadditionssalt deraf | |
| DK163580C (da) | Analogifremgangsmaade til fremstilling af cyclohexancarboxylsyrederivater | |
| DK357782A (da) | Fremgangsmaade til fremstilling af tetrahydrofurancarboxylsyrederivater | |
| DK156718C (da) | Analogifremgangsmaade til fremstilling af substituerede 2-phenyl-2-(pyridyloxy, pyridylamino eller pyridylthio)-ethylaminer eller syreadditionssalte deraf | |
| DK157673C (da) | Analogifremgangsmaade til fremstilling af phenylaliphatiske carboxylsyrederivater | |
| DK495780A (da) | Fremgangsmaade til fremstilling af 2-keto-l-gulonsyre eller salte deraf | |
| DK533881A (da) | Fremgangsmaade til fremstilling af 3,4-bis-substituerede 1,2,5-oxidazol-2-oxider eller farmekologisk acceptable syreadditionsforbindelser | |
| DK438482A (da) | Fremgangsmaade til fremstilling af indanderivater eller syreadditionssalte deraf | |
| DK98383D0 (da) | Fremgangsmade til fremstilling af 1,2,4-triazol-forbindelser eller farmaceutisk acceptable syreadditionssalte deraf | |
| DK211381A (da) | Fremgangsmaade til fremstilling af carbapenam3-carboxylsyre- eller carbapen-2-em-3-carboxylsyre-forbindelser eller estere eller salte deraf |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| AHS | Application shelved for other reasons than non-payment |