DK454178A - Acylanilider og fremgangsmaade til fremstilling deraf - Google Patents

Acylanilider og fremgangsmaade til fremstilling deraf

Info

Publication number
DK454178A
DK454178A DK454178A DK454178A DK454178A DK 454178 A DK454178 A DK 454178A DK 454178 A DK454178 A DK 454178A DK 454178 A DK454178 A DK 454178A DK 454178 A DK454178 A DK 454178A
Authority
DK
Denmark
Prior art keywords
acylanilides
manufacture
methods
Prior art date
Application number
DK454178A
Other languages
English (en)
Inventor
A T Glen
R W Bayles
Original Assignee
Ici Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ici Ltd filed Critical Ici Ltd
Publication of DK454178A publication Critical patent/DK454178A/da

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C255/00Carboxylic acid nitriles
    • C07C255/49Carboxylic acid nitriles having cyano groups bound to carbon atoms of six-membered aromatic rings of a carbon skeleton
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/04Centrally acting analgesics, e.g. opioids

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pain & Pain Management (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Biomedical Technology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
DK454178A 1977-10-12 1978-10-12 Acylanilider og fremgangsmaade til fremstilling deraf DK454178A (da)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB4245477 1977-10-12

Publications (1)

Publication Number Publication Date
DK454178A true DK454178A (da) 1979-04-13

Family

ID=10424506

Family Applications (1)

Application Number Title Priority Date Filing Date
DK454178A DK454178A (da) 1977-10-12 1978-10-12 Acylanilider og fremgangsmaade til fremstilling deraf

Country Status (10)

Country Link
US (2) US4239776A (da)
EP (1) EP0002309B1 (da)
JP (1) JPS5463047A (da)
AU (1) AU522624B2 (da)
DE (1) DE2862100D1 (da)
DK (1) DK454178A (da)
IE (1) IE47453B1 (da)
IT (1) IT1099707B (da)
NZ (1) NZ188626A (da)
ZA (1) ZA785698B (da)

Families Citing this family (109)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB8504093D0 (en) * 1985-02-18 1985-03-20 Ici Plc Alkene alkyne/cycloalkylene derivatives
US5236953A (en) * 1982-04-14 1993-08-17 Imperial Chemical Industries Plc Alkene, alkyne or cycloalkylene derivatives
ATE28864T1 (de) * 1982-07-23 1987-08-15 Ici Plc Amide-derivate.
GB8406000D0 (en) * 1984-03-07 1984-04-11 Ici Plc Olefine derivatives
US4760053A (en) * 1984-08-02 1988-07-26 Fernand Labrie Combination therapy for selected sex steroid dependent cancers
US4666885A (en) * 1985-02-08 1987-05-19 Fernand Labrie Combination therapy for treatment of female breast cancer
GB8617652D0 (en) * 1986-07-18 1986-08-28 Ici Plc Acylanilide derivatives
US4921941A (en) * 1987-07-01 1990-05-01 Schering Corporation Orally active antiandrogens
US4895715A (en) * 1988-04-14 1990-01-23 Schering Corporation Method of treating gynecomastia
GB8902323D0 (en) 1989-02-02 1989-03-22 Ici Plc Fungicides
IE62559B1 (en) * 1989-02-02 1995-02-08 Ici Plc Fungicides
GB9016580D0 (en) * 1990-07-27 1990-09-12 Ici Plc Fungicides
GB9016581D0 (en) * 1990-07-27 1990-09-12 Ici Plc Fungicides
GB9214120D0 (en) * 1991-07-25 1992-08-12 Ici Plc Therapeutic amides
TR27569A (tr) * 1992-01-24 1995-06-13 Ici Plc Yeni fungisidal asilaminobenzamidler, bunlarin hazirlanis islemleri ve bitkilerdeki mantar enfeksiyonlariyla mücadelede kullanimlari.
GB9305295D0 (en) * 1993-03-15 1993-05-05 Zeneca Ltd Therapeutic compounds
GB9310095D0 (en) * 1993-05-17 1993-06-30 Zeneca Ltd Therapeutic compounds
US5658953A (en) * 1995-04-03 1997-08-19 Centaur Pharmaceuticals, Inc. Pharmaceutical compositions of acetamidobenzamide compounds for neurodegenerative disorders
IL126004A (en) * 1996-03-21 2001-03-19 Hoechst Marion Roussel Inc Process for alkylating and smiles rearrangement of hydroxy aromatics
US5817874A (en) * 1996-03-21 1998-10-06 Hoechst Marion Roussel, Inc. Process for alkylating and smiles rearrangement of hydroxy aromatics
US6071957A (en) * 1996-11-27 2000-06-06 The University Of Tennessee Research Corporation Irreversible non-steroidal antagonist compound and its use in the treatment of prostate cancer
US7518013B2 (en) * 2000-08-24 2009-04-14 University Of Tennessee Research Foundation Selective androgen receptor modulators
US20050038110A1 (en) * 2000-08-24 2005-02-17 Steiner Mitchell S. Selective androgen receptor modulators and methods of use thereof
US6995284B2 (en) * 2000-08-24 2006-02-07 The University Of Tennessee Research Foundation Synthesis of selective androgen receptor modulators
US7759520B2 (en) * 1996-11-27 2010-07-20 University Of Tennessee Research Foundation Synthesis of selective androgen receptor modulators
WO1998053826A1 (en) * 1997-05-30 1998-12-03 The University Of Tennessee Research Corporation Non-steroidal agonist compounds and their use in male hormone therapy
US6019957A (en) * 1997-06-04 2000-02-01 The University Of Tennessee Research Corporation Non-steroidal radiolabeled agonist/antagonist compounds and their use in prostate cancer imaging
GB9804648D0 (en) 1998-03-06 1998-04-29 Zeneca Ltd Chemical compounds
GB9805520D0 (en) 1998-03-17 1998-05-13 Zeneca Ltd Chemical compounds
US20040176470A1 (en) * 1998-05-07 2004-09-09 Steiner Mitchell S. Method for treatment and chemoprevention of prostate cancer
GB9811427D0 (en) 1998-05-29 1998-07-22 Zeneca Ltd Chemical compounds
AU6715200A (en) 1999-09-04 2001-04-10 Astrazeneca Ab Amides as inhibitors for pyruvate dehydrogenase
DE60031699T2 (de) 1999-09-04 2007-08-30 Astrazeneca Ab Hydroxyacetamidobenzolsulfonamidderivate
DK1214296T3 (da) 1999-09-04 2004-07-05 Astrazeneca Ab Substituerede N-phenyl-2-hydroxy-2-methyl-3,3,3-trifluorpropanamidderivater, der forhöjer pyruvatdehydrogenaseaktivitet
US20040077605A1 (en) 2001-06-20 2004-04-22 Salvati Mark E. Fused heterocyclic succinimide compounds and analogs thereof, modulators of nuclear hormone receptor function
AU8821301A (en) 2000-06-28 2002-01-08 Bristol Myers Squibb Co Selective androgen receptor modulators and methods for their identification, design and use
US7001911B2 (en) * 2000-06-28 2006-02-21 Bristol-Myers Squibb Company Fused cyclic modulators of nuclear hormone receptor function
US7645898B2 (en) * 2000-08-24 2010-01-12 University Of Tennessee Research Foundation Selective androgen receptor modulators and method of use thereof
US7026500B2 (en) * 2000-08-24 2006-04-11 University Of Tennessee Research Foundation Halogenated selective androgen receptor modulators and methods of use thereof
IL154425A0 (en) 2000-08-24 2003-09-17 Univ Tennessee Res H Corp Selective androgen receptor modulators and methods of use thereof
US7622503B2 (en) * 2000-08-24 2009-11-24 University Of Tennessee Research Foundation Selective androgen receptor modulators and methods of use thereof
US6838484B2 (en) * 2000-08-24 2005-01-04 University Of Tennessee Research Foundation Formulations comprising selective androgen receptor modulators
US6998500B2 (en) * 2000-08-24 2006-02-14 University Of Tennessee Research Foundation Selective androgen receptor modulators and methods of use thereof
US8008348B2 (en) * 2001-12-06 2011-08-30 University Of Tennessee Research Foundation Treating muscle wasting with selective androgen receptor modulators
US20040260108A1 (en) * 2001-06-25 2004-12-23 Dalton James T. Metabolites of selective androgen receptor modulators and methods of use thereof
US20070173546A1 (en) * 2000-08-24 2007-07-26 Dalton James T Selective androgen receptor modulators and method of use thereof
US7855229B2 (en) * 2000-08-24 2010-12-21 University Of Tennessee Research Foundation Treating wasting disorders with selective androgen receptor modulators
US7919647B2 (en) * 2000-08-24 2011-04-05 University Of Tennessee Research Foundation Selective androgen receptor modulators and methods of use thereof
US8445534B2 (en) 2000-08-24 2013-05-21 University Of Tennessee Research Foundation Treating androgen decline in aging male (ADAM)-associated conditions with SARMs
AU8523001A (en) 2000-08-24 2002-03-04 Gtx Inc Selective androgen receptor modulators and methods of use thereof
US6953679B2 (en) 2000-09-19 2005-10-11 Bristol-Myers Squibb Company Method for the preparation of fused heterocyclic succinimide compounds and analogs thereof
EP1854798A3 (en) 2000-09-19 2007-11-28 Bristol-Myers Squibb Company Fused heterocyclic succinimide compounds and analogs thereof, modulators of nuclear hormone receptor function
US20040087548A1 (en) 2001-02-27 2004-05-06 Salvati Mark E. Fused cyclic succinimide compounds and analogs thereof, modulators of nuclear hormone receptor function
US20060287282A1 (en) * 2001-06-25 2006-12-21 Steiner Mitchell S Compositions comprising a SARM ad GnRH agonist or a GnRH antagonist, and methods of use thereof
US7015253B2 (en) * 2001-07-10 2006-03-21 American Medical Systems, Inc. Regimen for treating prostate tissue and surgical kit for use in the regimen
BR0215115A (pt) * 2001-12-06 2005-04-19 Gtx Inc Tratamento de perda muscular com moduladores de receptores de androgênio seletivos
US8853266B2 (en) * 2001-12-06 2014-10-07 University Of Tennessee Research Foundation Selective androgen receptor modulators for treating diabetes
US20070161608A1 (en) * 2001-12-06 2007-07-12 Dalton James T Selective androgen receptor modulators for treating muscle wasting
ATE404544T1 (de) 2001-12-19 2008-08-15 Bristol Myers Squibb Co Kondensierte heterocyclische verbindungen und deren analoga; modulatoren der funktion von nukleären hormonrezeptoren
BRPI0307699A2 (pt) * 2002-02-07 2015-06-16 Gtx Inc Tratamento de hiperplasia benigna da próstata com sarms.
US7344700B2 (en) * 2002-02-28 2008-03-18 University Of Tennessee Research Corporation Radiolabeled selective androgen receptor modulators and their use in prostate cancer imaging and therapy
US7803970B2 (en) * 2002-02-28 2010-09-28 University Of Tennessee Research Foundation Multi-substitued selective androgen receptor modulators and methods of use thereof
CA2476657A1 (en) * 2002-02-28 2003-09-12 The University Of Tennessee Research Corporation Haloacetamide and azide substituted compounds and methods of use thereof
KR101088352B1 (ko) * 2002-02-28 2011-11-30 유니버시티 오브 테네시 리서치 파운데이션 다치환된 선택적 안드로겐 수용체 조절자 및 이를 사용하는 방법
US7772433B2 (en) * 2002-02-28 2010-08-10 University Of Tennessee Research Foundation SARMS and method of use thereof
US7022870B2 (en) * 2002-06-17 2006-04-04 University Of Tennessee Research Foundation N-bridged selective androgen receptor modulators and methods of use thereof
US7741371B2 (en) * 2002-06-17 2010-06-22 University Of Tennessee Research Foundation Selective androgen receptor modulators and methods of use thereof
AU2003287077B2 (en) * 2002-10-15 2007-09-20 University Of Tennessee Research Foundation Methylene-bridged selective androgen receptor modulators and methods of use thereof
US20040197928A1 (en) * 2002-10-15 2004-10-07 Dalton James T. Method for detecting selective androgen receptor modulators
CA2501797A1 (en) * 2002-10-15 2004-04-29 Gtx, Inc. Treating obesity with selective androgen receptor modulators
CN1726020A (zh) * 2002-10-16 2006-01-25 Gtx公司 用sarm治疗老年男性雄激素缺乏(adam)相关的疾病
US20060276539A1 (en) * 2002-10-16 2006-12-07 Dalton James T Treating Androgen Decline in Aging Male (ADAM)- associated conditions with SARMS
US20040087810A1 (en) * 2002-10-23 2004-05-06 Dalton James T. Irreversible selective androgen receptor modulators and methods of use thereof
US8309603B2 (en) 2004-06-07 2012-11-13 University Of Tennessee Research Foundation SARMs and method of use thereof
US20040167103A1 (en) * 2003-02-24 2004-08-26 Dalton James T. Haloacetamide and azide substituted compounds and methods of use thereof
CN1805921A (zh) * 2003-12-16 2006-07-19 Gtx公司 选择性雄激素受体调节剂的前药及其使用方法
AP2006003700A0 (en) 2004-02-13 2006-08-31 Warner Lambert Co Androgen receptor modulators
US7507860B2 (en) 2004-04-13 2009-03-24 Pfizer Inc. Androgen modulators
CA2562672C (en) 2004-04-22 2009-09-29 Warner-Lambert Company Llc 4-cyano-phenoxy derivatives as androgen modulators
US9884038B2 (en) 2004-06-07 2018-02-06 University Of Tennessee Research Foundation Selective androgen receptor modulator and methods of use thereof
US20110237664A1 (en) * 2004-06-07 2011-09-29 Dalton James T Selective androgen receptor modulators for treating diabetes
US9889110B2 (en) 2004-06-07 2018-02-13 University Of Tennessee Research Foundation Selective androgen receptor modulator for treating hormone-related conditions
BRPI0513020A (pt) 2004-07-08 2008-04-22 Warner Lambert Co moduladores de andrÈgenio, seus usos, composição farmacêutica, formulação farmacêutica tópica e artigo de fabricação
US20060258628A1 (en) * 2004-07-20 2006-11-16 Steiner Mitchell S Compositions comprising 5-alpha reductase inhibitors, and SARMs and methods of use thereof
TW200724139A (en) 2005-05-05 2007-07-01 Warner Lambert Co Androgen modulators
US9730908B2 (en) 2006-08-24 2017-08-15 University Of Tennessee Research Foundation SARMs and method of use thereof
ES2581765T3 (es) 2006-08-24 2016-09-07 University Of Tennessee Research Foundation Acilanilidas sustituidas y métodos de uso de las mismas
US9844528B2 (en) 2006-08-24 2017-12-19 University Of Tennessee Research Foundation SARMs and method of use thereof
US10010521B2 (en) 2006-08-24 2018-07-03 University Of Tennessee Research Foundation SARMs and method of use thereof
EP4238519A3 (en) 2007-01-02 2023-11-29 AquaBeam LLC Minimally invasive methods and devices for the treatment of prostate diseases
US20220096112A1 (en) 2007-01-02 2022-03-31 Aquabeam, Llc Tissue resection with pressure sensing
US9232959B2 (en) 2007-01-02 2016-01-12 Aquabeam, Llc Multi fluid tissue resection methods and devices
US20080245375A1 (en) * 2007-04-05 2008-10-09 Medtronic Vascular, Inc. Benign Prostatic Hyperplasia Treatments
US7968603B2 (en) 2007-09-11 2011-06-28 University Of Tennessee Research Foundation Solid forms of selective androgen receptor modulators
EP2259742B1 (en) 2008-03-06 2020-01-01 AquaBeam LLC Tissue ablation and cautery with optical energy carried in fluid stream
US9848904B2 (en) 2009-03-06 2017-12-26 Procept Biorobotics Corporation Tissue resection and treatment with shedding pulses
EP2907504B1 (en) 2011-02-08 2017-06-28 Halozyme, Inc. Composition and lipid formulation of a hyaluronan-degrading enzyme and the use thereof for treatment of benign prostatic hyperplasia
BR112014021482B1 (pt) 2012-02-29 2021-12-21 Procept Biorobotics Corporation Aparelho de ressecção de próstata
LT2872482T (lt) 2012-07-13 2020-12-28 Oncternal Therapeutics, Inc. Krūties vėžių gydymo būdas selektyviu androgeno receptoriaus moduliatoriumi
US9969683B2 (en) 2012-07-13 2018-05-15 Gtx, Inc. Method of treating estrogen receptor (ER)-positive breast cancers with selective androgen receptor modulator (SARMS)
US10258596B2 (en) 2012-07-13 2019-04-16 Gtx, Inc. Method of treating HER2-positive breast cancers with selective androgen receptor modulators (SARMS)
US9744149B2 (en) 2012-07-13 2017-08-29 Gtx, Inc. Method of treating androgen receptor (AR)-positive breast cancers with selective androgen receptor modulator (SARMs)
US10987334B2 (en) 2012-07-13 2021-04-27 University Of Tennessee Research Foundation Method of treating ER mutant expressing breast cancers with selective androgen receptor modulators (SARMs)
US9622992B2 (en) 2012-07-13 2017-04-18 Gtx, Inc. Method of treating androgen receptor (AR)-positive breast cancers with selective androgen receptor modulator (SARMs)
US10314807B2 (en) 2012-07-13 2019-06-11 Gtx, Inc. Method of treating HER2-positive breast cancers with selective androgen receptor modulators (SARMS)
JP6403695B2 (ja) 2013-02-14 2018-10-10 プロセプト バイオロボティクス コーポレイション アクアアブレーションアクアビーム眼科手術方法および装置
BR112016005036A2 (pt) 2013-09-06 2020-04-07 Procept Biorobotics Corp aparelho para ressecção de tecido guiada por imagem automatizada
CN106572864B (zh) 2014-06-30 2020-06-09 普罗赛普特生物机器人公司 流体射流组织切除和寒凝装置
CN107072591B (zh) 2014-09-05 2021-10-26 普罗赛普特生物机器人公司 与靶器官图像的治疗映射结合的医师控制的组织切除

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3995060A (en) * 1972-06-20 1976-11-30 Schering Corporation Antiandrogenic agents and method for the treatment of androgen dependent disease states
CH489198A (de) 1967-10-19 1970-04-30 Ciba Geigy Schädlingsbekämpfungsmittel
DE2042300A1 (de) * 1970-08-26 1972-03-23 Farbwerke Hoechst AG, vormals Meister Lucius & Brüning, 6000 Frankfurt Halogencarbonsäureanilide, ihre Herstellung und Verwendung als Herbizide
DE2130450C3 (de) * 1971-06-19 1978-06-01 Scherico Ltd., Luzern (Schweiz) Antiandrogene pharmazeutische Zubereitungen
US3875229A (en) * 1972-11-24 1975-04-01 Schering Corp Substituted carboxanilides

Also Published As

Publication number Publication date
IT7828704A0 (it) 1978-10-12
IT1099707B (it) 1985-09-28
NZ188626A (en) 1981-01-23
ZA785698B (en) 1979-09-26
EP0002309A2 (en) 1979-06-13
US4282218A (en) 1981-08-04
JPS5463047A (en) 1979-05-21
DE2862100D1 (en) 1983-01-05
AU522624B2 (en) 1982-06-17
EP0002309B1 (en) 1982-12-01
EP0002309A3 (en) 1979-06-27
US4239776A (en) 1980-12-16
AU4061978A (en) 1980-04-17
IE47453B1 (en) 1984-03-21
IE782027L (en) 1979-04-12

Similar Documents

Publication Publication Date Title
DK454178A (da) Acylanilider og fremgangsmaade til fremstilling deraf
DK248078A (da) Phatalaziner og fremgangsmaade til fremstilling deraf
DK102177A (da) Aminoalkyl-heterocycliske forbindelser og fremgangsmade til fremstilling deraf
DK137378A (da) Taeppe og fremgangsmaade til fremstilling deraf
DK389478A (da) Termoplastiske aromatiske polyetherketoner og fremgangsmaade til fremstilling deraf
DK319277A (da) Hydroxysuccinimidestere fremgangsmade til fremstilling heraf og anvendelse heraf
DK372878A (da) Thiadiazolylcephalosporinanaloge og fremgangsmaade til fremstilling deraf
DK474078A (da) Endeloest forbindelsesbaand og fremgangsmaade til fremstilling deraf
DK502977A (da) Antracyklinderivat og fremgangsmaade til fremstilling deraf
DK335876A (da) 3-oximer af d-17alfa-ethynyl-19-nortestosteronestere og fremgangsmade til fremstilling deraf
DK308578A (da) Meningokokvaccine og fremgangsmaade til fremstilling heraf
DK96177A (da) 4-androsten-3-oner og fremgangsmade til fremstilling heraf
DK581378A (da) Keramisk form og fremgangsmaade til fremstilling deraf
DK266578A (da) Herbicide cyklopropylmethoxyanilider og fremgangsmaade til fremstilling deraf
DK12478A (da) Dithienylalkylaminer og fremgangsmaade til fremstilling deraf
DK554078A (da) Tetrapeptider og fremgangsmaade til fremstilling deraf
DK413578A (da) Isoquinolinderivater og fremgangsmaade til fremstilling deraf
DK36577A (da) Mufferor og fremgangsmade til fremstilling heraf
DK224279A (da) Polyjodbenzenderivater og fremgangsmaade til fremstilling deraf
DK151570C (da) Afsvovlningsmiddel og fremgangsmaade til fremstilling deraf
DK213878A (da) 17beta-hydroxy-4-androsten-3-on og fremgangsmaade til fremstilling heraf
DK54779A (da) Testosteronestere og fremgangsmaade til fremstilling deraf
DK111578A (da) Steroid/spirooxazolidiner og fremgangsmaade til fremstilling deraf
DK562478A (da) 3-di-n-propyl-acetoxy-benzodiazepin-2-oner og fremgangsmaade til fremstilling deraf
DK136879A (da) Brandhaemmende ologomere phosphatestere og fremgangsmaade til fremstilling deraf

Legal Events

Date Code Title Description
AHB Application shelved due to non-payment