DK452480A - Fremgangsmaade til fremstilling af (1-(4-chlorbenzoyl)-5-methoxy-2-methyl-3-indol)-acetoxyeddikesyre - Google Patents

Fremgangsmaade til fremstilling af (1-(4-chlorbenzoyl)-5-methoxy-2-methyl-3-indol)-acetoxyeddikesyre

Info

Publication number
DK452480A
DK452480A DK452480A DK452480A DK452480A DK 452480 A DK452480 A DK 452480A DK 452480 A DK452480 A DK 452480A DK 452480 A DK452480 A DK 452480A DK 452480 A DK452480 A DK 452480A
Authority
DK
Denmark
Prior art keywords
chlorobenzoyl
indol
methoxy
methyl
preparing
Prior art date
Application number
DK452480A
Other languages
Danish (da)
English (en)
Inventor
K H Boltze
S Raddatz
P R Seidel
Original Assignee
Troponwerke Dinklage & Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Troponwerke Dinklage & Co filed Critical Troponwerke Dinklage & Co
Publication of DK452480A publication Critical patent/DK452480A/da

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D207/00Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D207/02Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D207/18Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member
    • C07D207/22Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D207/24Oxygen or sulfur atoms
    • C07D207/262-Pyrrolidones
    • C07D207/2732-Pyrrolidones with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to other ring carbon atoms
    • C07D207/277Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
    • C07D207/282-Pyrrolidone-5- carboxylic acids; Functional derivatives thereof, e.g. esters, nitriles
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pain & Pain Management (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Rheumatology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Indole Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
DK452480A 1979-10-25 1980-10-24 Fremgangsmaade til fremstilling af (1-(4-chlorbenzoyl)-5-methoxy-2-methyl-3-indol)-acetoxyeddikesyre DK452480A (da)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE19792943125 DE2943125A1 (de) 1979-10-25 1979-10-25 Verfahren zur herstellung von 1-(4-chlorbenzoyl)-5-methoxy-2-methyl-3-indol acetoxyessigsaeure

Publications (1)

Publication Number Publication Date
DK452480A true DK452480A (da) 1981-04-26

Family

ID=6084363

Family Applications (1)

Application Number Title Priority Date Filing Date
DK452480A DK452480A (da) 1979-10-25 1980-10-24 Fremgangsmaade til fremstilling af (1-(4-chlorbenzoyl)-5-methoxy-2-methyl-3-indol)-acetoxyeddikesyre

Country Status (13)

Country Link
US (1) US4332727A (fr)
EP (1) EP0027956A1 (fr)
JP (1) JPS5668667A (fr)
AU (1) AU532859B2 (fr)
CA (1) CA1148540A (fr)
DE (1) DE2943125A1 (fr)
DK (1) DK452480A (fr)
ES (1) ES496249A0 (fr)
FI (1) FI803320L (fr)
GR (1) GR70767B (fr)
IL (1) IL61328A (fr)
PT (1) PT71921B (fr)
ZA (1) ZA806544B (fr)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CH653326A5 (de) * 1981-12-28 1985-12-31 Siegfried Ag Verfahren zur herstellung eines indolderivates.
DE3206885A1 (de) * 1982-02-26 1983-09-15 Troponwerke GmbH & Co KG, 5000 Köln Indolderivate, verfahren zu ihrer herstellung und ihre verwendung als arzneimittel
DE3206889A1 (de) * 1982-02-26 1983-09-15 Troponwerke GmbH & Co KG, 5000 Köln Verfahren zur herstellung von 1-(4-chlorbenzoyl)-5-methoxy-2-methyl-3-indolacetoxyessigsaeure
HUP9904567A3 (en) 1996-06-20 2001-10-29 Univ Texas Use of azo, thioalkyl, thiocarbonyl derivatives substituted by fused heterocycles and/or phenyl group for the preparation of pharmaceutical compositions stimulating bone growth

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AT290523B (de) * 1962-01-05 1971-06-11 Merck & Co Inc Verfahren zur Herstellung neuer α-(3-Indolyl)-carbonsäuren
DE2234651C3 (de) * 1972-07-14 1978-11-09 Troponwerke Gmbh & Co Kg, 5000 Koeln Eckige Klammer auf l-(p-Chlorbenzoyl)-5-methoxy-2-methyl-3-indol] -acetoxj essigsaure, ihre Salze mit Basen, Verfahren zu ihrer Herstellung sowie pharmakologische Zubereitungen
DE2413125C2 (de) * 1974-03-15 1983-06-30 Schering Ag, 1000 Berlin Und 4619 Bergkamen Indolylacetylaminosäurederivate, Verfahren zu deren Herstellung und diese Verbindungen enthaltende Arzneipräparate
JPS52156862A (en) * 1976-06-22 1977-12-27 Hisamitsu Pharmaceut Co Inc Novel indoleacetic acid ester derivatives
DE2740852A1 (de) * 1977-09-10 1979-03-29 Troponwerke Gmbh & Co Kg Basische 1-acylindol-3-acetocyessigsaeureester, verfahren zu ihrer herstellung und ihre verwendung als arzneimittel
DE2740836A1 (de) * 1977-09-10 1979-03-22 Troponwerke Gmbh & Co Kg Anellierte indolderivate, verfahren zu ihrer herstellung und ihre verwendung als arzneimittel
DE2752361A1 (de) * 1977-11-24 1979-06-07 Troponwerke Gmbh & Co Kg Neue indolderivate, verfahren zu ihrer herstellung und ihre verwendung als arzneimittel

Also Published As

Publication number Publication date
JPS5668667A (en) 1981-06-09
EP0027956A1 (fr) 1981-05-06
DE2943125A1 (de) 1981-05-14
PT71921A (de) 1980-11-01
US4332727A (en) 1982-06-01
PT71921B (de) 1981-08-31
CA1148540A (fr) 1983-06-21
AU532859B2 (en) 1983-10-13
ZA806544B (en) 1981-11-25
ES8106889A1 (es) 1981-09-16
FI803320L (fi) 1981-04-26
ES496249A0 (es) 1981-09-16
IL61328A (en) 1983-06-15
GR70767B (fr) 1983-03-16
IL61328A0 (en) 1980-12-31

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Legal Events

Date Code Title Description
AHB Application shelved due to non-payment