DK425586D0 - Fremgangsmaade til bestemmelse af proteaseinhibitorer - Google Patents

Fremgangsmaade til bestemmelse af proteaseinhibitorer

Info

Publication number
DK425586D0
DK425586D0 DK425586A DK425586A DK425586D0 DK 425586 D0 DK425586 D0 DK 425586D0 DK 425586 A DK425586 A DK 425586A DK 425586 A DK425586 A DK 425586A DK 425586 D0 DK425586 D0 DK 425586D0
Authority
DK
Denmark
Prior art keywords
procedure
protease inhibitors
protease
determining protease
substrate
Prior art date
Application number
DK425586A
Other languages
English (en)
Other versions
DK425586A (da
Inventor
Hans-Juergen Kolde
Original Assignee
Behringwerke Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=6280238&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=DK425586(D0) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Behringwerke Ag filed Critical Behringwerke Ag
Publication of DK425586D0 publication Critical patent/DK425586D0/da
Publication of DK425586A publication Critical patent/DK425586A/da

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/56—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving blood clotting factors, e.g. involving thrombin, thromboplastin, fibrinogen
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/34—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving hydrolase
    • C12Q1/37—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving hydrolase involving peptidase or proteinase
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2337/00—N-linked chromogens for determinations of peptidases and proteinases
    • C12Q2337/10—Anilides
    • C12Q2337/12—Para-Nitroanilides p-NA
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
    • G01N2333/81—Protease inhibitors
    • G01N2333/8107—Endopeptidase (E.C. 3.4.21-99) inhibitors
    • G01N2333/811—Serine protease (E.C. 3.4.21) inhibitors
    • G01N2333/8121—Serpins
    • G01N2333/8128—Antithrombin III
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
    • G01N2333/90—Enzymes; Proenzymes
    • G01N2333/914—Hydrolases (3)
    • G01N2333/948—Hydrolases (3) acting on peptide bonds (3.4)
    • G01N2333/95—Proteinases, i.e. endopeptidases (3.4.21-3.4.99)
    • G01N2333/964—Proteinases, i.e. endopeptidases (3.4.21-3.4.99) derived from animal tissue
    • G01N2333/96425—Proteinases, i.e. endopeptidases (3.4.21-3.4.99) derived from animal tissue from mammals
    • G01N2333/96427—Proteinases, i.e. endopeptidases (3.4.21-3.4.99) derived from animal tissue from mammals in general
    • G01N2333/9643—Proteinases, i.e. endopeptidases (3.4.21-3.4.99) derived from animal tissue from mammals in general with EC number
    • G01N2333/96433—Serine endopeptidases (3.4.21)
    • G01N2333/96441—Serine endopeptidases (3.4.21) with definite EC number
    • G01N2333/96444—Factor X (3.4.21.6)
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
    • G01N2333/90—Enzymes; Proenzymes
    • G01N2333/914—Hydrolases (3)
    • G01N2333/948—Hydrolases (3) acting on peptide bonds (3.4)
    • G01N2333/974—Thrombin

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Wood Science & Technology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Zoology (AREA)
  • Engineering & Computer Science (AREA)
  • Immunology (AREA)
  • General Engineering & Computer Science (AREA)
  • Microbiology (AREA)
  • Molecular Biology (AREA)
  • Analytical Chemistry (AREA)
  • Biotechnology (AREA)
  • Physics & Mathematics (AREA)
  • Biochemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biophysics (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Hematology (AREA)
  • Neurosurgery (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Investigating Or Analysing Materials By The Use Of Chemical Reactions (AREA)
  • Peptides Or Proteins (AREA)
DK425586A 1985-09-06 1986-09-05 Fremgangsmaade til bestemmelse af proteaseinhibitorer DK425586A (da)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE19853531778 DE3531778A1 (de) 1985-09-06 1985-09-06 Verfahren zur bestimmung von proteaseinhibitoren

Publications (2)

Publication Number Publication Date
DK425586D0 true DK425586D0 (da) 1986-09-05
DK425586A DK425586A (da) 1987-03-07

Family

ID=6280238

Family Applications (1)

Application Number Title Priority Date Filing Date
DK425586A DK425586A (da) 1985-09-06 1986-09-05 Fremgangsmaade til bestemmelse af proteaseinhibitorer

Country Status (10)

Country Link
US (1) US4918001A (da)
EP (1) EP0216179B1 (da)
JP (1) JPS6261600A (da)
AT (1) ATE66493T1 (da)
AU (1) AU611847B2 (da)
CA (1) CA1292174C (da)
DE (2) DE3531778A1 (da)
DK (1) DK425586A (da)
ES (1) ES2000974A6 (da)
NZ (1) NZ217459A (da)

Families Citing this family (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5011910A (en) * 1989-12-28 1991-04-30 Washington University Reagent and method for determining activity of retroviral protease
US5171662A (en) * 1990-09-13 1992-12-15 The Upjohn Company Method of detecting HIV protease activity
US5292652A (en) * 1990-10-05 1994-03-08 Athena Neurosciences, Inc. Amyloidin protease and uses thereof
US5235039A (en) * 1991-06-10 1993-08-10 Eli Lilly And Company Substrates for hiv protease
US5308755A (en) * 1992-06-08 1994-05-03 Research Corporation Technologies, Inc. Method for measuring heparin
JPH078298A (ja) 1993-06-28 1995-01-13 Nippon Shoji Kk アンチトロンビンｉｉｉ活性の測定方法および該測定用試薬キット
JP2968048B2 (ja) * 1995-05-12 1999-10-25 シェーリング コーポレイション 表面プラズモン共鳴に基づく酵素アッセイ
US5705353A (en) * 1995-06-07 1998-01-06 Beckman Instruments, Inc. Method of reducing interferences in assays
EP0814167A1 (en) * 1996-06-21 1997-12-29 Kabushiki Kaisha Kyoto Daiichi Kagaku A method for measuring the concentration of protease inhibitors, kit for use in such a method and method for dissolving a sunstrate
JP3626982B2 (ja) * 1997-08-29 2005-03-09 アークレイ株式会社 タンパク質分解酵素阻害物質の測定方法およびそれに用いる測定キット
US5985582A (en) * 1997-12-09 1999-11-16 Sigma-Aldrich Co. Thrombin-based assay for antithrombin III
ES2302860T3 (es) * 2001-11-08 2008-08-01 Tibotec Pharmaceuticals Ltd. Ensayo de proteasas para la monitorizacion terapeutica de farmacos.
DE102006008613A1 (de) 2006-02-24 2007-08-30 Dade Behring Marburg Gmbh Stabilisierte Zubereitungen von Serin-Endopeptidasen, deren Herstellung und Verwendung
JP5442781B2 (ja) * 2011-01-31 2014-03-12 三洋化成工業株式会社 プロテアーゼ活性回復方法

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3912704A (en) * 1972-05-08 1975-10-14 Ayerst Mckenna & Harrison Protease inhibitor from horse urine
EP0048989B1 (en) * 1980-09-30 1985-09-04 Cornell Research Foundation, Inc. Process for determining inhibitor-enzyme complexes
US4493891A (en) * 1982-07-27 1985-01-15 University Of Georgia Research Foundation, Inc. Determination of oxidized α-1-proteinase inhibitor in serum or plasma
FI68262C (fi) * 1982-12-17 1985-08-12 Labsystems Oy Foerfarande foer konstatering av juverinflammation
CA1254119A (en) * 1984-07-20 1989-05-16 Lloyd A. Schick Single step protease inhibitor assay

Also Published As

Publication number Publication date
US4918001A (en) 1990-04-17
DE3680978D1 (de) 1991-09-26
NZ217459A (en) 1989-03-29
JPS6261600A (ja) 1987-03-18
ES2000974A6 (es) 1988-04-01
AU6236786A (en) 1987-03-12
EP0216179A1 (de) 1987-04-01
ATE66493T1 (de) 1991-09-15
CA1292174C (en) 1991-11-19
EP0216179B1 (de) 1991-08-21
AU611847B2 (en) 1991-06-27
DE3531778A1 (de) 1987-03-12
DK425586A (da) 1987-03-07

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