DK412084D0 - Benzoylurinstofderivater og antitumorpraeparat indeholdende et saadant derivat - Google Patents
Benzoylurinstofderivater og antitumorpraeparat indeholdende et saadant derivatInfo
- Publication number
- DK412084D0 DK412084D0 DK412084A DK412084A DK412084D0 DK 412084 D0 DK412084 D0 DK 412084D0 DK 412084 A DK412084 A DK 412084A DK 412084 A DK412084 A DK 412084A DK 412084 D0 DK412084 D0 DK 412084D0
- Authority
- DK
- Denmark
- Prior art keywords
- compounds
- benzoylurine
- ingredients
- derivative
- preparations containing
- Prior art date
Links
- 230000000259 anti-tumor effect Effects 0.000 title abstract 2
- 239000004615 ingredient Substances 0.000 title 1
- 238000002360 preparation method Methods 0.000 title 1
- 150000001875 compounds Chemical class 0.000 abstract 4
- HRYILSDLIGTCOP-UHFFFAOYSA-N N-benzoylurea Chemical class NC(=O)NC(=O)C1=CC=CC=C1 HRYILSDLIGTCOP-UHFFFAOYSA-N 0.000 abstract 1
- 230000015572 biosynthetic process Effects 0.000 abstract 1
- 230000000694 effects Effects 0.000 abstract 1
- 125000002887 hydroxy group Chemical group [H]O* 0.000 abstract 1
- 238000000034 method Methods 0.000 abstract 1
- 125000001997 phenyl group Chemical group [H]C1=C([H])C([H])=C(*)C([H])=C1[H] 0.000 abstract 1
- 238000003786 synthesis reaction Methods 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C275/00—Derivatives of urea, i.e. compounds containing any of the groups, the nitrogen atoms not being part of nitro or nitroso groups
- C07C275/46—Derivatives of urea, i.e. compounds containing any of the groups, the nitrogen atoms not being part of nitro or nitroso groups containing any of the groups, X being a hetero atom, Y being any atom, e.g. acylureas
- C07C275/48—Y being a hydrogen or a carbon atom
- C07C275/54—Y being a carbon atom of a six-membered aromatic ring, e.g. benzoylureas
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C335/00—Thioureas, i.e. compounds containing any of the groups, the nitrogen atoms not being part of nitro or nitroso groups
- C07C335/04—Derivatives of thiourea
- C07C335/24—Derivatives of thiourea containing any of the groups, X being a hetero atom, Y being any atom
- C07C335/26—Y being a hydrogen or a carbon atom, e.g. benzoylthioureas
Landscapes
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| NL8303043 | 1983-09-01 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| DK412084D0 true DK412084D0 (da) | 1984-08-29 |
| DK412084A DK412084A (da) | 1985-03-02 |
Family
ID=19842331
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DK412084A DK412084A (da) | 1983-09-01 | 1984-08-29 | Benzoylurinstofderivater og antitumorpraeparat indeholdende et saadant derivat |
Country Status (13)
| Country | Link |
|---|---|
| EP (1) | EP0136745B1 (da) |
| JP (1) | JPS60120847A (da) |
| AT (1) | ATE43788T1 (da) |
| AU (1) | AU572549B2 (da) |
| CA (1) | CA1252791A (da) |
| DE (1) | DE3478573D1 (da) |
| DK (1) | DK412084A (da) |
| ES (1) | ES535491A0 (da) |
| GR (1) | GR80221B (da) |
| IL (1) | IL72818A0 (da) |
| NZ (1) | NZ209365A (da) |
| PH (1) | PH23038A (da) |
| ZA (1) | ZA846767B (da) |
Families Citing this family (29)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| ATE40111T1 (de) * | 1984-07-05 | 1989-02-15 | Duphar Int Res | Benzoylharnstoffverbindungen sowie solche enthaltende insektizide und akarizide zusammensetzungen. |
| EP0173244B1 (de) * | 1984-08-24 | 1990-02-07 | Ciba-Geigy Ag | Benzoylphenylharnstoffe |
| TR23048A (tr) * | 1984-08-31 | 1989-02-14 | Ciba Geigy Ag | Fenilbenzoiluereler,bunlarin im aline mahsus usul ve bunlarin zararhlarla muecadelede kullanimi |
| IL76708A (en) * | 1984-10-18 | 1990-01-18 | Ciba Geigy Ag | Substituted n-benzoyl-n'-(2,5-dichloro-4(1,1,2,3,3,3-hexafluoropropyloxy)-phenyl)ureas,their preparation and pesticidal compositions containing them |
| US5153224A (en) * | 1984-10-18 | 1992-10-06 | Ciba-Geigy Corporation | Benzoylphenylureas |
| EP0179021A3 (de) * | 1984-10-18 | 1987-05-13 | Ciba-Geigy Ag | Benzoylphenylharnstoffe |
| US5135953A (en) * | 1984-12-28 | 1992-08-04 | Ciba-Geigy | Use of acyl urea compounds for controlling endoparasites and ectoparasites of warm-blooded animals |
| DK88186A (da) * | 1985-03-01 | 1986-09-02 | Duphar Int Res | Benzoylurinstofderivater med antitumoraktivitet |
| AU602305B2 (en) * | 1985-03-14 | 1990-10-11 | Istituto Guido Donegani S.P.A. | N-(halobenzoyl)-N-(polyhaloalkoxyphenyl) urea derivatives |
| JPH0742267B2 (ja) * | 1985-06-04 | 1995-05-10 | 日本曹達株式会社 | ベンゾイルウレア誘導体、その製造方法及び殺虫剤 |
| DE3741062A1 (de) * | 1987-12-04 | 1989-08-31 | Hoechst Ag | (thio)benzoylharnstoffe und deren funktionelle derivate, verfahren zu ihrer herstellung, sie enthaltende mittel und ihre verwendung als schaedlingsbekaempfungsmittel |
| AU642524B2 (en) * | 1990-09-10 | 1993-10-21 | Duphar International Research B.V. | Pharmaceutical formulation containing a benzoyl urea derivative |
| GB9313268D0 (en) * | 1993-06-28 | 1993-08-11 | Zeneca Ltd | Chemical compounds |
| US5463011A (en) * | 1993-06-28 | 1995-10-31 | Zeneca Limited | Acid derivatives |
| GB9313285D0 (en) * | 1993-06-28 | 1993-08-11 | Zeneca Ltd | Acid derivatives |
| IL153273A0 (en) * | 2000-06-09 | 2003-07-06 | Aventis Pharma Gmbh | Acylphenyl urea derivatives, methods for the production thereof and use thereof as a medicament |
| PE20021091A1 (es) | 2001-05-25 | 2003-02-04 | Aventis Pharma Gmbh | Derivados de fenilurea sustituidos con carbonamida y procedimiento para su preparacion |
| US7223796B2 (en) | 2002-04-11 | 2007-05-29 | Sanofi-Aventis Deutschland Gmbh | Acyl-4-carboxyphenylurea derivatives, processes for preparing them and their use |
| IL164249A0 (en) * | 2002-04-11 | 2005-12-18 | Aventis Pharma Gmbh | Acyl-3-carboxphenylurea derivatives, processes forpreparing them and their use |
| US7297709B2 (en) | 2003-05-22 | 2007-11-20 | Abbott Laboratories | Indazole, benzisoxazole, and benzisothiazole kinase inhibitors |
| DE10335092B3 (de) * | 2003-08-01 | 2005-02-03 | Aventis Pharma Deutschland Gmbh | Substituierte Benzoylureido-o-benzoylamide, Verfahren zu deren Herstellung und deren Verwendung |
| WO2008029096A2 (en) | 2006-09-04 | 2008-03-13 | University Court Of The University Of Dundee | P53 activating benzoyl urea and benzoyl thiourea compounds |
| CN101880246B (zh) * | 2009-05-05 | 2012-10-03 | 中国科学院上海药物研究所 | 取代苯甲酰脲类化合物及其制备方法和用途 |
| GB0909912D0 (en) | 2009-06-09 | 2009-07-22 | Univ Dundee | Compounds |
| DK2917212T3 (da) * | 2012-11-08 | 2019-09-23 | Univ Rutgers | Antimikrobielle midler |
| US9458150B2 (en) | 2013-11-08 | 2016-10-04 | Rutgers, The State University Of New Jersey | Antimicrobial agents |
| US10513528B2 (en) | 2016-02-25 | 2019-12-24 | Taxis Pharmaceuticals, Inc. | Synthetic processes and intermediates |
| US10774093B2 (en) | 2017-03-30 | 2020-09-15 | Taxis Pharmaceuticals, Inc. | Synthetic processes and synthetic intermediates |
| CN113004183B (zh) * | 2021-02-08 | 2023-03-14 | 中山大学附属第三医院（中山大学肝脏病医院） | 一种索拉非尼抗肿瘤抑制助剂化合物及其组合物和应用 |
Family Cites Families (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS5640667A (en) * | 1979-09-11 | 1981-04-16 | Ishihara Sangyo Kaisha Ltd | Urea derivative |
| IL69621A0 (en) * | 1982-09-02 | 1983-12-30 | Duphar Int Res | Pharmaceutical compositions having antitumor activity,comprising certain phenylurea derivatives |
| ATE28862T1 (de) * | 1983-01-24 | 1987-08-15 | Duphar Int Res | Aktive kompositionen gegen motten, weisse fliegen und holzwuermer, pharmazeutische kompositionen und benzoylharnstoffderivaten. |
| DK147084A (da) * | 1983-03-19 | 1984-09-20 | Bayer Ag | 1-phenyl-3-benzoyl-(thio)-urinstoffer, deres fremstilling og anvendelse som skadedyrsbekaempelsesmidler |
| IT1161228B (it) * | 1983-04-22 | 1987-03-18 | Montedison Spa | Benzoil-uree ad attivita' insetticida |
-
1984
- 1984-08-27 AT AT84201221T patent/ATE43788T1/de active
- 1984-08-27 EP EP84201221A patent/EP0136745B1/en not_active Expired
- 1984-08-27 DE DE8484201221T patent/DE3478573D1/de not_active Expired
- 1984-08-28 GR GR80221A patent/GR80221B/el unknown
- 1984-08-29 AU AU32504/84A patent/AU572549B2/en not_active Ceased
- 1984-08-29 ZA ZA846767A patent/ZA846767B/xx unknown
- 1984-08-29 NZ NZ209365A patent/NZ209365A/xx unknown
- 1984-08-29 CA CA000461993A patent/CA1252791A/en not_active Expired
- 1984-08-29 ES ES535491A patent/ES535491A0/es active Granted
- 1984-08-29 DK DK412084A patent/DK412084A/da not_active Application Discontinuation
- 1984-08-30 IL IL72818A patent/IL72818A0/xx unknown
- 1984-08-31 JP JP59182516A patent/JPS60120847A/ja active Pending
- 1984-08-31 PH PH31171A patent/PH23038A/en unknown
Also Published As
| Publication number | Publication date |
|---|---|
| GR80221B (en) | 1984-12-14 |
| ATE43788T1 (de) | 1989-06-15 |
| CA1252791A (en) | 1989-04-18 |
| ES8505338A1 (es) | 1985-05-16 |
| PH23038A (en) | 1989-03-10 |
| NZ209365A (en) | 1989-07-27 |
| IL72818A0 (en) | 1984-11-30 |
| DE3478573D1 (en) | 1989-07-13 |
| EP0136745A3 (en) | 1986-01-22 |
| EP0136745B1 (en) | 1989-06-07 |
| DK412084A (da) | 1985-03-02 |
| ES535491A0 (es) | 1985-05-16 |
| ZA846767B (en) | 1985-04-24 |
| EP0136745A2 (en) | 1985-04-10 |
| AU572549B2 (en) | 1988-05-12 |
| AU3250484A (en) | 1985-03-07 |
| JPS60120847A (ja) | 1985-06-28 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| AHS | Application shelved for other reasons than non-payment |