GR80221B - Benzoyl urea derivatives having anti-tumor activity - Google Patents
Benzoyl urea derivatives having anti-tumor activityInfo
- Publication number
- GR80221B GR80221B GR80221A GR840180221A GR80221B GR 80221 B GR80221 B GR 80221B GR 80221 A GR80221 A GR 80221A GR 840180221 A GR840180221 A GR 840180221A GR 80221 B GR80221 B GR 80221B
- Authority
- GR
- Greece
- Prior art keywords
- compounds
- urea derivatives
- tumor activity
- benzoyl urea
- found
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C275/00—Derivatives of urea, i.e. compounds containing any of the groups, the nitrogen atoms not being part of nitro or nitroso groups
- C07C275/46—Derivatives of urea, i.e. compounds containing any of the groups, the nitrogen atoms not being part of nitro or nitroso groups containing any of the groups, X being a hetero atom, Y being any atom, e.g. acylureas
- C07C275/48—Y being a hydrogen or a carbon atom
- C07C275/54—Y being a carbon atom of a six-membered aromatic ring, e.g. benzoylureas
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C335/00—Thioureas, i.e. compounds containing any of the groups, the nitrogen atoms not being part of nitro or nitroso groups
- C07C335/04—Derivatives of thiourea
- C07C335/24—Derivatives of thiourea containing any of the groups, X being a hetero atom, Y being any atom
- C07C335/26—Y being a hydrogen or a carbon atom, e.g. benzoylthioureas
Landscapes
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
NL8303043 | 1983-09-01 |
Publications (1)
Publication Number | Publication Date |
---|---|
GR80221B true GR80221B (en) | 1984-12-14 |
Family
ID=19842331
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
GR80221A GR80221B (en) | 1983-09-01 | 1984-08-28 | Benzoyl urea derivatives having anti-tumor activity |
Country Status (13)
Country | Link |
---|---|
EP (1) | EP0136745B1 (el) |
JP (1) | JPS60120847A (el) |
AT (1) | ATE43788T1 (el) |
AU (1) | AU572549B2 (el) |
CA (1) | CA1252791A (el) |
DE (1) | DE3478573D1 (el) |
DK (1) | DK412084A (el) |
ES (1) | ES535491A0 (el) |
GR (1) | GR80221B (el) |
IL (1) | IL72818A0 (el) |
NZ (1) | NZ209365A (el) |
PH (1) | PH23038A (el) |
ZA (1) | ZA846767B (el) |
Families Citing this family (29)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
ATE40111T1 (de) * | 1984-07-05 | 1989-02-15 | Duphar Int Res | Benzoylharnstoffverbindungen sowie solche enthaltende insektizide und akarizide zusammensetzungen. |
GB2163430B (en) * | 1984-08-24 | 1988-05-25 | Ciba Geigy Ag | Pesticidal benzoylphenylureas |
TR23048A (tr) * | 1984-08-31 | 1989-02-14 | Ciba Geigy Ag | Fenilbenzoiluereler,bunlarin im aline mahsus usul ve bunlarin zararhlarla muecadelede kullanimi |
US5153224A (en) * | 1984-10-18 | 1992-10-06 | Ciba-Geigy Corporation | Benzoylphenylureas |
EP0179021A3 (de) * | 1984-10-18 | 1987-05-13 | Ciba-Geigy Ag | Benzoylphenylharnstoffe |
DE3580444D1 (en) * | 1984-10-18 | 1990-12-13 | Ciba Geigy Ag | Benzoylphenylharnstoffe. |
US5135953A (en) * | 1984-12-28 | 1992-08-04 | Ciba-Geigy | Use of acyl urea compounds for controlling endoparasites and ectoparasites of warm-blooded animals |
IE860511L (en) * | 1985-03-01 | 1986-09-01 | Alfa Farmaceutici Spa | "Benzoyl urea derivatives having anti-tumor activity" |
AU602305B2 (en) * | 1985-03-14 | 1990-10-11 | Istituto Guido Donegani S.P.A. | N-(halobenzoyl)-N-(polyhaloalkoxyphenyl) urea derivatives |
JPH0742267B2 (ja) * | 1985-06-04 | 1995-05-10 | 日本曹達株式会社 | ベンゾイルウレア誘導体、その製造方法及び殺虫剤 |
DE3741062A1 (de) * | 1987-12-04 | 1989-08-31 | Hoechst Ag | (thio)benzoylharnstoffe und deren funktionelle derivate, verfahren zu ihrer herstellung, sie enthaltende mittel und ihre verwendung als schaedlingsbekaempfungsmittel |
AU642524B2 (en) * | 1990-09-10 | 1993-10-21 | Duphar International Research B.V. | Pharmaceutical formulation containing a benzoyl urea derivative |
US5463011A (en) * | 1993-06-28 | 1995-10-31 | Zeneca Limited | Acid derivatives |
GB9313268D0 (en) * | 1993-06-28 | 1993-08-11 | Zeneca Ltd | Chemical compounds |
GB9313285D0 (en) * | 1993-06-28 | 1993-08-11 | Zeneca Ltd | Acid derivatives |
ES2215902T3 (es) * | 2000-06-09 | 2004-10-16 | Aventis Pharma Deutschland Gmbh | Derivados de acil-fenil-ureas, procedimiento para su preparacion y su utilizacion como medicamentos. |
PE20021091A1 (es) | 2001-05-25 | 2003-02-04 | Aventis Pharma Gmbh | Derivados de fenilurea sustituidos con carbonamida y procedimiento para su preparacion |
US7223796B2 (en) | 2002-04-11 | 2007-05-29 | Sanofi-Aventis Deutschland Gmbh | Acyl-4-carboxyphenylurea derivatives, processes for preparing them and their use |
DE10215907A1 (de) * | 2002-04-11 | 2003-11-06 | Aventis Pharma Gmbh | Acyl-4-carboxyphenyl-harnstoffderivate, Verfahren zu deren Herstellung und deren Verwendung |
US7297709B2 (en) | 2003-05-22 | 2007-11-20 | Abbott Laboratories | Indazole, benzisoxazole, and benzisothiazole kinase inhibitors |
DE10335092B3 (de) * | 2003-08-01 | 2005-02-03 | Aventis Pharma Deutschland Gmbh | Substituierte Benzoylureido-o-benzoylamide, Verfahren zu deren Herstellung und deren Verwendung |
US8501991B2 (en) | 2006-09-04 | 2013-08-06 | University Court Of The University Of Dundee | P53 activating compounds |
CN101880246B (zh) * | 2009-05-05 | 2012-10-03 | 中国科学院上海药物研究所 | 取代苯甲酰脲类化合物及其制备方法和用途 |
GB0909912D0 (en) | 2009-06-09 | 2009-07-22 | Univ Dundee | Compounds |
CA2891092C (en) * | 2012-11-08 | 2020-12-15 | Taxis Pharmaceuticals, Inc. | Antimicrobial agents |
US9458150B2 (en) | 2013-11-08 | 2016-10-04 | Rutgers, The State University Of New Jersey | Antimicrobial agents |
CA3015768A1 (en) | 2016-02-25 | 2017-08-31 | Taxis Pharmaceuticals, Inc. | Synthetic processes and intermediates |
CN110891566B (zh) | 2017-03-30 | 2023-12-19 | 塔克西斯医药股份有限公司 | 合成方法和合成中间体 |
CN113004183B (zh) * | 2021-02-08 | 2023-03-14 | 中山大学附属第三医院(中山大学肝脏病医院) | 一种索拉非尼抗肿瘤抑制助剂化合物及其组合物和应用 |
Family Cites Families (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JPS5640667A (en) * | 1979-09-11 | 1981-04-16 | Ishihara Sangyo Kaisha Ltd | Urea derivative |
AU1862083A (en) * | 1982-09-02 | 1984-03-08 | Duphar International Research B.V. | Tumor growth inhibitors |
EP0116728B1 (en) * | 1983-01-24 | 1987-08-12 | Duphar International Research B.V | Composition active against mites, whitefly and thrips, pharmaceutical composition, and new benzoylureau compounds |
DK147084A (da) * | 1983-03-19 | 1984-09-20 | Bayer Ag | 1-phenyl-3-benzoyl-(thio)-urinstoffer, deres fremstilling og anvendelse som skadedyrsbekaempelsesmidler |
IT1161228B (it) * | 1983-04-22 | 1987-03-18 | Montedison Spa | Benzoil-uree ad attivita' insetticida |
-
1984
- 1984-08-27 AT AT84201221T patent/ATE43788T1/de active
- 1984-08-27 EP EP84201221A patent/EP0136745B1/en not_active Expired
- 1984-08-27 DE DE8484201221T patent/DE3478573D1/de not_active Expired
- 1984-08-28 GR GR80221A patent/GR80221B/el unknown
- 1984-08-29 ZA ZA846767A patent/ZA846767B/xx unknown
- 1984-08-29 ES ES535491A patent/ES535491A0/es active Granted
- 1984-08-29 NZ NZ209365A patent/NZ209365A/xx unknown
- 1984-08-29 AU AU32504/84A patent/AU572549B2/en not_active Ceased
- 1984-08-29 CA CA000461993A patent/CA1252791A/en not_active Expired
- 1984-08-29 DK DK412084A patent/DK412084A/da not_active Application Discontinuation
- 1984-08-30 IL IL72818A patent/IL72818A0/xx unknown
- 1984-08-31 JP JP59182516A patent/JPS60120847A/ja active Pending
- 1984-08-31 PH PH31171A patent/PH23038A/en unknown
Also Published As
Publication number | Publication date |
---|---|
PH23038A (en) | 1989-03-10 |
AU3250484A (en) | 1985-03-07 |
IL72818A0 (en) | 1984-11-30 |
JPS60120847A (ja) | 1985-06-28 |
EP0136745A2 (en) | 1985-04-10 |
DK412084D0 (da) | 1984-08-29 |
DE3478573D1 (en) | 1989-07-13 |
EP0136745B1 (en) | 1989-06-07 |
NZ209365A (en) | 1989-07-27 |
CA1252791A (en) | 1989-04-18 |
ES8505338A1 (es) | 1985-05-16 |
ZA846767B (en) | 1985-04-24 |
ES535491A0 (es) | 1985-05-16 |
EP0136745A3 (en) | 1986-01-22 |
ATE43788T1 (de) | 1989-06-15 |
AU572549B2 (en) | 1988-05-12 |
DK412084A (da) | 1985-03-02 |
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