DK408083A - Isoquinolinderivater, deres fremstilling og anvendelse - Google Patents

Isoquinolinderivater, deres fremstilling og anvendelse Download PDF

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Publication number
DK408083A
DK408083A DK408083A DK408083A DK408083A DK 408083 A DK408083 A DK 408083A DK 408083 A DK408083 A DK 408083A DK 408083 A DK408083 A DK 408083A DK 408083 A DK408083 A DK 408083A
Authority
DK
Denmark
Prior art keywords
preparation
isoquinoline derivatives
isoquinoline
meansings
compounds
Prior art date
Application number
DK408083A
Other languages
Danish (da)
English (en)
Other versions
DK408083D0 (da
Inventor
Elmar Konz
Joachim Kaiser
Original Assignee
Hoechst Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hoechst Ag filed Critical Hoechst Ag
Publication of DK408083D0 publication Critical patent/DK408083D0/da
Publication of DK408083A publication Critical patent/DK408083A/da

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Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D215/00Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
    • C07D215/02Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
    • C07D215/16Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D401/00Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/12Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/06Antiarrhythmics
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D217/00Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems
    • C07D217/22Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to carbon atoms of the nitrogen-containing ring
    • C07D217/26Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Cardiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Animal Behavior & Ethology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Other In-Based Heterocyclic Compounds (AREA)
  • Macromolecular Compounds Obtained By Forming Nitrogen-Containing Linkages In General (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
  • Polysaccharides And Polysaccharide Derivatives (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
DK408083A 1982-09-09 1983-09-08 Isoquinolinderivater, deres fremstilling og anvendelse DK408083A (da)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE19823233424 DE3233424A1 (de) 1982-09-09 1982-09-09 Isochinolinderivate, verfahren zu ihrer herstellung, pharmazeutische praeparate auf basis dieser verbindungen und ihre verwendung

Publications (2)

Publication Number Publication Date
DK408083D0 DK408083D0 (da) 1983-09-08
DK408083A true DK408083A (da) 1984-03-10

Family

ID=6172780

Family Applications (1)

Application Number Title Priority Date Filing Date
DK408083A DK408083A (da) 1982-09-09 1983-09-08 Isoquinolinderivater, deres fremstilling og anvendelse

Country Status (19)

Country Link
US (1) US4673682A (xx)
EP (1) EP0105210B1 (xx)
JP (1) JPS5967270A (xx)
KR (1) KR840006206A (xx)
AT (1) ATE25679T1 (xx)
AU (1) AU1891683A (xx)
CA (1) CA1211445A (xx)
DE (2) DE3233424A1 (xx)
DK (1) DK408083A (xx)
ES (1) ES8404852A1 (xx)
FI (1) FI833200A (xx)
GR (1) GR79382B (xx)
HU (1) HU191094B (xx)
IL (1) IL69683A0 (xx)
NO (1) NO833217L (xx)
NZ (1) NZ205513A (xx)
PH (1) PH18186A (xx)
PT (1) PT77309B (xx)
ZA (1) ZA836663B (xx)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4956371A (en) * 1989-09-19 1990-09-11 Euroceltique, S.A. Substituted isoquinolines and methods of using same
EP0590455B1 (en) * 1992-09-28 2000-12-27 Hoechst Aktiengesellschaft Antiarrhythmic and cardioprotective substituted 1(2H)-isoquinolines, process for their production, medicament containing them and their use for the production of a medicament for combating heart failures
CN102977015B (zh) 2003-06-06 2015-05-06 菲布罗根有限公司 含氮杂芳基化合物及其在增加内源性促红细胞生成素中的用途
CN103382216B (zh) * 2006-01-27 2016-04-20 菲布罗根有限公司 使低氧诱导因子(hif)稳定的氰基异喹啉化合物
CA2647596C (en) * 2006-04-04 2012-06-12 Fibrogen, Inc. Pyrrolo- and thiazolo-pyridine compounds as hif modulators
WO2010056767A1 (en) 2008-11-14 2010-05-20 Fibrogen, Inc. Thiochromene derivatives as hip hydroxylase inhibitors
EP2834220B1 (en) 2012-03-09 2016-11-09 Fibrogen, Inc. 4-hydroxy-isoquinoline compounds as hif hydroxylase inhibitors
US8883823B2 (en) 2012-07-16 2014-11-11 Fibrogen, Inc. Crystalline forms of a prolyl hydroxylase inhibitor
CN107540607A (zh) 2012-07-16 2018-01-05 菲布罗根有限公司 脯氨酰羟化酶抑制剂的晶体形态
MY171483A (en) 2012-07-16 2019-10-15 Fibrogen Inc Process for making isoquinoline compounds
RU2666144C2 (ru) 2013-01-24 2018-09-06 Фиброген, Инк. Кристаллические формы { [1-циано-5-(4-хлорофенокси)-4-гидроксиизохинолин-3-карбонил]-амино} -уксусной кислоты

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2054482B1 (xx) * 1969-07-11 1973-06-08 Anvar
FR2424270A1 (fr) * 1978-04-24 1979-11-23 Rhone Poulenc Ind Nouveaux derives de l'isoquinoleine, leur preparation et les compositions qui les contiennent
DE2818423A1 (de) * 1978-04-27 1979-11-08 Hoechst Ag Neue isochinolinderivate und verfahren zu ihrer herstellung

Also Published As

Publication number Publication date
EP0105210A3 (en) 1984-10-10
ZA836663B (en) 1984-04-25
PT77309B (de) 1986-04-18
DE3233424A1 (de) 1984-03-15
FI833200A (fi) 1984-03-10
ES525441A0 (es) 1984-05-16
CA1211445A (en) 1986-09-16
EP0105210B1 (de) 1987-03-04
NZ205513A (en) 1986-05-09
PT77309A (de) 1983-10-01
HU191094B (en) 1987-01-28
ES8404852A1 (es) 1984-05-16
AU1891683A (en) 1984-03-15
EP0105210A2 (de) 1984-04-11
NO833217L (no) 1984-03-12
IL69683A0 (en) 1983-12-30
JPS5967270A (ja) 1984-04-16
DE3369983D1 (en) 1987-04-09
US4673682A (en) 1987-06-16
DK408083D0 (da) 1983-09-08
ATE25679T1 (de) 1987-03-15
GR79382B (xx) 1984-10-22
FI833200A0 (fi) 1983-09-07
KR840006206A (ko) 1984-11-22
PH18186A (en) 1985-04-12

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