DK39991A - Oral immunisering - Google Patents
Oral immunisering Download PDFInfo
- Publication number
- DK39991A DK39991A DK039991A DK39991A DK39991A DK 39991 A DK39991 A DK 39991A DK 039991 A DK039991 A DK 039991A DK 39991 A DK39991 A DK 39991A DK 39991 A DK39991 A DK 39991A
- Authority
- DK
- Denmark
- Prior art keywords
- oral immunization
- humans
- animals
- directed
- transgenic plants
- Prior art date
Links
- 230000003053 immunization Effects 0.000 title abstract 2
- 238000002649 immunization Methods 0.000 title abstract 2
- 241001465754 Metazoa Species 0.000 abstract 2
- 244000000010 microbial pathogen Species 0.000 abstract 2
- 230000009261 transgenic effect Effects 0.000 abstract 2
- 239000000427 antigen Substances 0.000 abstract 1
- 108091007433 antigens Proteins 0.000 abstract 1
- 102000036639 antigens Human genes 0.000 abstract 1
- 230000028993 immune response Effects 0.000 abstract 1
- 230000009545 invasion Effects 0.000 abstract 1
- 108090000623 proteins and genes Proteins 0.000 abstract 1
- 230000003248 secreting effect Effects 0.000 abstract 1
- 230000001018 virulence Effects 0.000 abstract 1
Classifications
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/10—Transferases (2.)
- C12N9/1048—Glycosyltransferases (2.4)
- C12N9/1051—Hexosyltransferases (2.4.1)
-
- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01H—NEW PLANTS OR NON-TRANSGENIC PROCESSES FOR OBTAINING THEM; PLANT REPRODUCTION BY TISSUE CULTURE TECHNIQUES
- A01H5/00—Angiosperms, i.e. flowering plants, characterised by their plant parts; Angiosperms characterised otherwise than by their botanic taxonomy
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/195—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
- C07K14/24—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Enterobacteriaceae (F), e.g. Citrobacter, Serratia, Proteus, Providencia, Morganella, Yersinia
- C07K14/245—Escherichia (G)
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/195—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
- C07K14/315—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Streptococcus (G), e.g. Enterococci
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
- C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
- C12N15/82—Vectors or expression systems specially adapted for eukaryotic hosts for plant cells, e.g. plant artificial chromosomes (PACs)
- C12N15/8241—Phenotypically and genetically modified plants via recombinant DNA technology
- C12N15/8242—Phenotypically and genetically modified plants via recombinant DNA technology with non-agronomic quality (output) traits, e.g. for industrial processing; Value added, non-agronomic traits
- C12N15/8257—Phenotypically and genetically modified plants via recombinant DNA technology with non-agronomic quality (output) traits, e.g. for industrial processing; Value added, non-agronomic traits for the production of primary gene products, e.g. pharmaceutical products, interferon
- C12N15/8258—Phenotypically and genetically modified plants via recombinant DNA technology with non-agronomic quality (output) traits, e.g. for industrial processing; Value added, non-agronomic traits for the production of primary gene products, e.g. pharmaceutical products, interferon for the production of oral vaccines (antigens) or immunoglobulins
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/14—Hydrolases (3)
- C12N9/16—Hydrolases (3) acting on ester bonds (3.1)
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/14—Hydrolases (3)
- C12N9/24—Hydrolases (3) acting on glycosyl compounds (3.2)
- C12N9/2402—Hydrolases (3) acting on glycosyl compounds (3.2) hydrolysing O- and S- glycosyl compounds (3.2.1)
- C12N9/2405—Glucanases
- C12N9/2451—Glucanases acting on alpha-1,6-glucosidic bonds
- C12N9/2454—Dextranase (3.2.1.11)
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Y—ENZYMES
- C12Y301/00—Hydrolases acting on ester bonds (3.1)
- C12Y301/03—Phosphoric monoester hydrolases (3.1.3)
- C12Y301/03001—Alkaline phosphatase (3.1.3.1)
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Y—ENZYMES
- C12Y302/00—Hydrolases acting on glycosyl compounds, i.e. glycosylases (3.2)
- C12Y302/01—Glycosidases, i.e. enzymes hydrolysing O- and S-glycosyl compounds (3.2.1)
- C12Y302/01011—Dextranase (3.2.1.11)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
- Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
- Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Genetics & Genomics (AREA)
- Organic Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Zoology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Wood Science & Technology (AREA)
- General Health & Medical Sciences (AREA)
- Biochemistry (AREA)
- Molecular Biology (AREA)
- General Engineering & Computer Science (AREA)
- Medicinal Chemistry (AREA)
- Biomedical Technology (AREA)
- Biotechnology (AREA)
- Microbiology (AREA)
- Biophysics (AREA)
- Gastroenterology & Hepatology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Plant Pathology (AREA)
- Physics & Mathematics (AREA)
- Cell Biology (AREA)
- Pharmacology & Pharmacy (AREA)
- Immunology (AREA)
- Developmental Biology & Embryology (AREA)
- Botany (AREA)
- Physiology (AREA)
- Environmental Sciences (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Agricultural Chemicals And Associated Chemicals (AREA)
- Medicines Containing Plant Substances (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Peptides Or Proteins (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Breeding Of Plants And Reproduction By Means Of Culturing (AREA)
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US24072888A | 1988-09-06 | 1988-09-06 | |
US39852089A | 1989-08-29 | 1989-08-29 | |
PCT/US1989/003799 WO1990002484A1 (en) | 1988-09-06 | 1989-09-05 | Oral immunization by transgenic plants |
Publications (2)
Publication Number | Publication Date |
---|---|
DK39991D0 DK39991D0 (da) | 1991-03-06 |
DK39991A true DK39991A (da) | 1991-05-01 |
Family
ID=26933652
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DK039991A DK39991A (da) | 1988-09-06 | 1991-03-06 | Oral immunisering |
Country Status (12)
Country | Link |
---|---|
US (3) | US5679880A (ja) |
EP (1) | EP0433372B1 (ja) |
JP (2) | JPH04501801A (ja) |
KR (1) | KR900701152A (ja) |
AT (1) | ATE218797T1 (ja) |
AU (1) | AU634178B2 (ja) |
CA (1) | CA1339307C (ja) |
DE (1) | DE68929405T2 (ja) |
DK (1) | DK39991A (ja) |
IL (1) | IL91525A0 (ja) |
NZ (1) | NZ230576A (ja) |
WO (1) | WO1990002484A1 (ja) |
Families Citing this family (107)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP0351924A3 (en) * | 1988-07-20 | 1991-04-03 | Nickerson Seeds Limited | Improvements relating to transgenic plants |
AU644619B2 (en) * | 1989-12-21 | 1993-12-16 | Advanced Technologies (Cambridge) Limited | Modification of plant metabolism |
IL97645A (en) * | 1990-03-23 | 1997-03-18 | Gist Brocades Nv | Production of enzymes in seeds and their use |
US7033627B2 (en) | 1990-03-23 | 2006-04-25 | Syngenta Mogen B.V. | Production of enzymes in seeds and their use |
US5593963A (en) * | 1990-09-21 | 1997-01-14 | Mogen International | Expression of phytase in plants |
US5543576A (en) * | 1990-03-23 | 1996-08-06 | Mogen International | Production of enzymes in seeds and their use |
SE9100556D0 (sv) * | 1991-02-26 | 1991-02-26 | Holmgren Jan | Preparation and use of formalin-killed colonization-factor-antigen (cfa)-expressing e coli organisms for vaccination against enteric infection/diarrhea caused by enterotoxigenic e coli bacteria in humans |
US6034298A (en) * | 1991-08-26 | 2000-03-07 | Prodigene, Inc. | Vaccines expressed in plants |
US20010053367A1 (en) * | 1991-08-26 | 2001-12-20 | Prodigene, Inc. | Vaccines expressed in plants |
US5612487A (en) * | 1991-08-26 | 1997-03-18 | Edible Vaccines, Inc. | Anti-viral vaccines expressed in plants |
US5484719A (en) * | 1991-08-26 | 1996-01-16 | Edible Vaccines, Inc. | Vaccines produced and administered through edible plants |
GB9403819D0 (en) * | 1994-02-28 | 1994-04-20 | Univ Leeds | Control of parasites |
US7118758B1 (en) | 1997-01-24 | 2006-10-10 | The United States Of America As Represented By The Secretary Of The Army | Transformed bacteria producing CS6 antigens as vaccines |
EP0759993B1 (en) | 1994-05-18 | 2007-07-25 | Bayer BioScience GmbH | Dna sequences coding for enzymes capable of facilitating the synthesis of linear alpha-1,4 glucans in plants, fungi and microorganisms |
US6140075A (en) * | 1994-07-25 | 2000-10-31 | Monsanto Company | Method for producing antibodies and protein toxins in plant cells |
US6080560A (en) * | 1994-07-25 | 2000-06-27 | Monsanto Company | Method for producing antibodies in plant cells |
AUPM764394A0 (en) * | 1994-08-24 | 1994-09-15 | Giffard, Philip M. | Genetic manipulation of plants to increase stored carbohydrates |
AU702520B2 (en) * | 1994-08-24 | 1999-02-25 | Philip Morrison Giffard | Genetic manipulation of plants to increase stored carbohydrates |
WO1996012801A1 (en) | 1994-10-24 | 1996-05-02 | The Texas A & M University System | Oral immunization with transgenic plants |
US5716837A (en) | 1995-02-10 | 1998-02-10 | Monsanto Company | Expression of sucrose phosphorylase in plants |
US6127602A (en) * | 1995-06-07 | 2000-10-03 | Pioneer Hi-Bred International, Inc. | Plant cells and plants transformed with streptococcus mutans genes encoding wild-type or mutant glucosyltransferase D enzymes |
US5985666A (en) * | 1995-06-07 | 1999-11-16 | Pioneer Hi-Bred International, Inc. | Forages |
WO1996040229A1 (en) * | 1995-06-07 | 1996-12-19 | Thomas Jefferson University | Vaccines synthesized by transgenic plants |
US6087559A (en) * | 1995-06-07 | 2000-07-11 | Pioneer Hi-Bred International, Inc. | Plant cells and plants transformed with Streptococcus mutans genes encoding wild-type or mutant glucosyltransferase B enzymes |
US6284479B1 (en) | 1995-06-07 | 2001-09-04 | Pioneer Hi-Bred International, Inc. | Substitutes for modified starch and latexes in paper manufacture |
US5712107A (en) * | 1995-06-07 | 1998-01-27 | Pioneer Hi-Bred International, Inc. | Substitutes for modified starch and latexes in paper manufacture |
WO1997010347A1 (en) * | 1995-09-15 | 1997-03-20 | Howard John A | Expression cassettes and methods for delivery of animal vaccines |
US5922583A (en) * | 1995-10-17 | 1999-07-13 | Biostar Inc. | Methods for production of recombinant plasmids |
US6395964B1 (en) | 1995-10-24 | 2002-05-28 | The Texas A&M University System | Oral immunization with transgenic plants |
WO1997040161A1 (en) | 1996-04-19 | 1997-10-30 | Henry M. Jackson Foundation For The Advancement Of Military Medecine | Histidine-tagged intimin and methods of using intimin to stimulate an immune response and as an antigen carrier with targeting capability |
AU722327B2 (en) | 1996-04-19 | 2000-07-27 | Henry M. Jackson Foundation For The Advancement Of Military Medicine | Method of stimulating an immune response by administration of host organisms that express intimin alone or as a fusion protein with one or more other antigens |
AU5597998A (en) * | 1996-12-04 | 1998-06-29 | Heska Corporation | Recombinant plague vaccine |
US7422747B2 (en) * | 1997-10-07 | 2008-09-09 | Loma Linda University | Transgenic plant-based vaccines |
US6777546B2 (en) * | 1997-10-07 | 2004-08-17 | Loma Linda University | Methods and substances for preventing and treating autoimmune disease |
US20050241024A1 (en) * | 1997-10-07 | 2005-10-27 | Langridge William H | Transgenic plant-based vaccines |
US20050186219A1 (en) * | 1997-10-07 | 2005-08-25 | Langridge William H. | Transgenic plant-based vaccines |
US6551820B1 (en) * | 1998-12-23 | 2003-04-22 | Boyce Thompson Institute For Plant Research | Expression of immunogenic hepatitis B surface antigens in transgenic plants |
ES2296642T3 (es) * | 1999-09-21 | 2008-05-01 | Rutgers, The State University Of New Jersey | Sistema de recombinacion especifica de sitio para manipular el genoma de plastidos de plantas superiores. |
US7186560B2 (en) * | 1999-09-21 | 2007-03-06 | Rutgers, The State University Of New Jersey | High level expression of immunogenic proteins in the plastids of higher plants |
US7572466B1 (en) | 1999-10-13 | 2009-08-11 | Health Research, Inc. | Oral immunology using plant product containing a non-enteric pathogen antigen |
US7527810B1 (en) | 1999-10-13 | 2009-05-05 | Health Research, Inc. | Oral immunology using plant product containing hepatitis surface antigen |
EP1254156A4 (en) * | 2000-01-27 | 2003-05-21 | Univ Loma Linda | TRANSGENIC PLANT VACCINES |
US20040081654A1 (en) * | 2000-06-16 | 2004-04-29 | Schryvers Anthony B | Use of plant oil-bodies in vaccine delivery systems |
US6932980B1 (en) * | 2001-01-18 | 2005-08-23 | Richard Sayre | Method of making microalgal-based animal foodstuff supplements, microalgal-supplemented animal foodstuffs and method of animal nutrition |
WO2001098335A2 (en) * | 2000-06-20 | 2001-12-27 | Phycotransgenics, Llc | Transgenic algae for delivering antigens to an animal |
US20030138769A1 (en) * | 2000-08-16 | 2003-07-24 | Birkett Ashley J. | Immunogenic HBc chimer particles having enhanced stability |
AU2002252525A1 (en) * | 2001-03-29 | 2002-10-15 | Rutgers, The University Of New Jersey | Integrases for the insertion of heterologous nucleic acids into the plastid genome |
WO2002083072A2 (en) * | 2001-04-13 | 2002-10-24 | Boyce Thompson Institute For Plant Research | Methods and compositions for stable transgenic plant pharmaceuticals and their use as contraceptives |
JP4771656B2 (ja) * | 2001-05-30 | 2011-09-14 | カリックス・バイオ−ベンチャーズ・インコーポレイテッド | 植物人工染色体、その使用及び植物人工染色体の製造方法 |
US7361352B2 (en) * | 2001-08-15 | 2008-04-22 | Acambis, Inc. | Influenza immunogen and vaccine |
US20030185858A1 (en) * | 2001-08-15 | 2003-10-02 | Birkett Ashley J. | Immunogenic HBc chimer particles stabilized with an N-terminal cysteine |
US20030175863A1 (en) * | 2001-08-15 | 2003-09-18 | Birkett Ashley J. | Influenza immunogen and vaccine |
EP2395083B1 (en) | 2002-01-08 | 2017-04-12 | Agrivida, Inc. | Transgenic plants expressing CIVPS or intein modified proteins and related method |
AU2003225612A1 (en) * | 2002-02-27 | 2003-09-09 | Prodigene, Inc. | Expression of hiv-related proteins in plants |
US20040175440A1 (en) * | 2002-04-12 | 2004-09-09 | Boyce Thompson Institute | Methods and compositions for stable transgenic plant pharmaceuticals and their use as contraceptives |
US7329798B2 (en) * | 2002-06-28 | 2008-02-12 | University Of Guelph | Harvest-inducible regulatory elements and methods of using same |
EP1517605A2 (en) | 2002-06-28 | 2005-03-30 | University of Guelph | Harvest-inducible genes from alfalfa (medicago sativa) and methods of use thereof |
US20040014704A1 (en) * | 2002-07-18 | 2004-01-22 | Gonzalo Hortelano | Oral administration of therapeutic agent coupled to transporting agent induces tolerance |
US20040016013A1 (en) * | 2002-07-18 | 2004-01-22 | Gonzalo Hortelano | Transgenic animals produced using oral administration of a genetic agent coupled to a transporting agent |
US20040014698A1 (en) * | 2002-07-18 | 2004-01-22 | Gonzalo Hortelano | Oral administration of therapeutic agent coupled to transporting agent |
AU2003274925A1 (en) * | 2002-08-27 | 2004-03-19 | Dow Agrosciences Llc | Use of escherichia coli heat labile toxin as an adjuvant in birds and poultry |
AU2003287622A1 (en) * | 2002-11-06 | 2004-06-03 | Fraunhofer Usa | Expression of foreign sequences in plants using trans-activation system |
US7692063B2 (en) * | 2002-11-12 | 2010-04-06 | Ibio, Inc. | Production of foreign nucleic acids and polypeptides in sprout systems |
US7683238B2 (en) * | 2002-11-12 | 2010-03-23 | iBio, Inc. and Fraunhofer USA, Inc. | Production of pharmaceutically active proteins in sprouted seedlings |
TWI350310B (en) | 2002-12-13 | 2011-10-11 | Novartis Ag | Immunization of fish with plant-expressed recombinant proteins |
WO2004070016A2 (en) * | 2003-02-03 | 2004-08-19 | Fraunhofer Usa Inc. | System for expression of genes in plants |
EP1606386A4 (en) * | 2003-03-03 | 2007-07-18 | Univ Rutgers | REMOVAL OF PLASTIC SEQUENCES THROUGH TRANSIENT EXPRESSED LOCATION-SPECIFIC RECOMBINATION |
KR20060029214A (ko) * | 2003-05-05 | 2006-04-05 | 다우 아그로사이언시즈 엘엘씨 | 이식 유전자 식물 세포들로부터 유래된 안정한 면역예방적및 치료적 조성물들 및 생산방법 |
CA2524293A1 (en) | 2003-05-05 | 2004-11-18 | Boyce Thompson Institute For Plant Research | Vectors and cells for preparing immunoprotective compositions derived from transgenic plants |
WO2005032457A2 (en) | 2003-07-21 | 2005-04-14 | Boyce Thompson Institute For Plant Research, Inc. | Vectors and methods for immunization against norwalk virus using transgenic plants |
AU2004297259A1 (en) * | 2003-12-09 | 2005-06-23 | Ventria Bioscience | High-level expression of fusion polypeptides in plant seeds utilizing seed-storage proteins as fusion carriers |
US20050208032A1 (en) * | 2004-01-16 | 2005-09-22 | Gonzalo Hortelano | Oral administration of therapeutic agent coupled to transporting agent |
CA2555230A1 (en) | 2004-02-20 | 2005-09-09 | Fraunhofer Usa Inc. | Systems and methods for clonal expression in plants |
EP1751288A2 (en) * | 2004-05-19 | 2007-02-14 | Agrivida, Inc. | Transgenic plants expressing intein modified proteins and associated processes for bio-pharmaceutical production |
AU2005248233C1 (en) | 2004-05-31 | 2010-08-19 | Hokusan Co. Ltd. | Oral anti-protozoiasis vaccines based on transgenic plants |
KR20080075855A (ko) | 2005-11-04 | 2008-08-19 | 다우 아그로사이언시즈 엘엘씨 | 재조합 식물 현탁배양을 이용한 백신 마스터 세포주제조방법 |
US8163880B2 (en) | 2006-02-23 | 2012-04-24 | Era Biotech S.A. | Production of biologically active proteins |
WO2007121467A2 (en) * | 2006-04-18 | 2007-10-25 | Rutgers, The State University Of New Jersey | Compositions and methods for increasing transgene expression in the plastids of higher plants |
US20080089957A1 (en) * | 2006-10-11 | 2008-04-17 | Shui-Tein Chen | Monocotyledon plant indications extract compositions, method of preparation and pharmaceutical compositions containing them |
WO2008141226A2 (en) * | 2007-05-10 | 2008-11-20 | The Arizona Board Of Regents For And On Behalf Of Arizona State University | Recombinant bacteria comprising vectors for expression of nucleic acid sequences encoding antigens |
WO2009025888A2 (en) | 2007-05-10 | 2009-02-26 | The Arizona Board Of Regents For And On Behalf Of Arizona State University | Regulated synthesis of antigen and/or regulated attentuation to enhance vaccine immunogenics and/or safety |
WO2009046449A1 (en) | 2007-10-05 | 2009-04-09 | The Arizona Board Of Regents For And On Behalf Of Arizona State University | Recombinant bacterium capable of eliciting an immune response against enteric pathogens |
MX2010011938A (es) | 2008-05-02 | 2010-12-01 | Idemitsu Kosan Co | Vacuna para toxina bacteriana. |
WO2010045620A1 (en) | 2008-10-17 | 2010-04-22 | The Arizona Board Of Regents For And On Behalf Of Arizona State University | Recombinant bacterium capable of eliciting an immune response against streptococcus pneumoniae |
US20100183523A1 (en) * | 2009-01-22 | 2010-07-22 | Wagner Richard E | Dental composition and method |
US9163219B2 (en) | 2009-04-14 | 2015-10-20 | Arizona Board Of Regents On Behalf Of Arizona State University | Single expression vector for generation of a virus with a segmented genome |
WO2010135563A1 (en) | 2009-05-22 | 2010-11-25 | The Arizona Board Of Regents For And On Behalf Of Arizona State University | Recombinant bacterium and methods of antigen and nucleic acid delivery |
US9045742B2 (en) | 2009-05-29 | 2015-06-02 | The Arizona Board Of Regents For And On Behalf Of Arizona State University | Recombinant Edwardsiella bacterium |
EP2435080A2 (en) * | 2009-05-29 | 2012-04-04 | Abbott Laboratories | Pharmaceutical compositions for the treatment of pain |
US9464333B2 (en) | 2009-11-06 | 2016-10-11 | Agrivida, Inc. | Intein-modified enzymes, their production and industrial applications |
US10407742B2 (en) | 2009-11-06 | 2019-09-10 | Agrivida, Inc. | Intein-modified enzymes, their production and industrial applications |
US8420387B2 (en) | 2009-11-06 | 2013-04-16 | Agrivida, Inc. | Intein-modified enzymes, their production and industrial applications |
US9062297B2 (en) | 2010-01-13 | 2015-06-23 | The Arizona Board Of Regents For And On Behalf Of Arizona State University | Yersinia pestis vaccine |
WO2011091291A1 (en) | 2010-01-22 | 2011-07-28 | The Arizona Board Of Regents For And On Behalf Of Arizona State University | BACTERIUM COMPRISING A REGULATED rfaH NUCLEIC ACID |
WO2011150421A2 (en) | 2010-05-28 | 2011-12-01 | The Arizona Board Of Regents For And On Behalf Of Arizona State University | Recombinant bacterium to decrease tumor growth |
EP2418284A1 (en) | 2010-08-13 | 2012-02-15 | ERA Biotech, S.A. | Protein body-inducing polypeptide sequences |
US10443068B2 (en) | 2010-06-25 | 2019-10-15 | Agrivida, Inc. | Plants with engineered endogenous genes |
US9598700B2 (en) | 2010-06-25 | 2017-03-21 | Agrivida, Inc. | Methods and compositions for processing biomass with elevated levels of starch |
WO2012003460A2 (en) | 2010-07-02 | 2012-01-05 | The Arizona Board Of Regents For And On Behalf Of Arizona State University | Compositions and methods for bacterial lysis and neutral lipid production |
CN102008720B (zh) * | 2010-07-20 | 2015-02-25 | 东北农业大学 | 抗魏氏梭菌病转基因植物疫苗及其制作方法 |
ES2610923T3 (es) | 2011-03-07 | 2017-05-04 | Agrivida, Inc. | Pretratamiento consolidado e hidrólisis de biomasa vegetal que expresa enzimas de degradación de pared celular |
US10150970B2 (en) | 2011-07-27 | 2018-12-11 | Applied Biotechnology Institute, Inc. | Methods to increase antigenicity of membrane-bound polypeptides produced in plants |
US9303264B2 (en) | 2012-05-18 | 2016-04-05 | The Arizona Board Of Regents For And On Behalf Of Arizona State University | Photosynthetic microorganisms expressing thermostable lipase |
GB201222183D0 (en) * | 2012-12-10 | 2013-01-23 | Univ Manchester | Polysaccharides |
US9580718B2 (en) | 2013-06-17 | 2017-02-28 | Arizona Board Of Regents On Behalf Of Arizona State University | Attenuated live bacteria with increased acid resistance and methods of use thereof |
US10617751B2 (en) | 2017-07-13 | 2020-04-14 | VisionTech International Limited | Edible vaccines expressed in yeast for preventing and treating infectious diseases in animals and humans |
US10973908B1 (en) | 2020-05-14 | 2021-04-13 | David Gordon Bermudes | Expression of SARS-CoV-2 spike protein receptor binding domain in attenuated salmonella as a vaccine |
Family Cites Families (10)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO1982003088A1 (en) * | 1981-03-09 | 1982-09-16 | Corp Cetus | Vaccines |
US4888170A (en) * | 1981-10-22 | 1989-12-19 | Research Corporation | Vaccines obtained from antigenic gene products of recombinant genes |
CA1338705C (en) * | 1981-10-22 | 1996-11-12 | Roy Curtiss Iii | Vaccines obtained from antigenic gene products of recombinant genes |
US4784949A (en) * | 1984-04-19 | 1988-11-15 | Cetus Corporation | Universal dominant selectable marker cassette |
US4771002A (en) * | 1984-02-24 | 1988-09-13 | Lubrizol Genetics, Inc. | Transcription in plants and bacteria |
US4774182A (en) * | 1984-06-29 | 1988-09-27 | Wisconsin Alumni Research Foundation | Partially defective foreign gene for conferring immunity on a biological host |
CA1340372C (en) * | 1984-07-09 | 1999-02-02 | John D. Clements | Production of e. coli lt-b enterotoxin subunit |
US4894332A (en) * | 1985-03-27 | 1990-01-16 | Biogen, Inc. | DNA sequences coding for Mycoplasma hypopneumoniae surface antigens, methods of use to make the corresponding proteins |
IL78775A (en) * | 1985-05-15 | 1992-06-21 | Biotech Australia Pty Ltd | Oral vaccines |
US4956282A (en) * | 1985-07-29 | 1990-09-11 | Calgene, Inc. | Mammalian peptide expression in plant cells |
-
1989
- 1989-09-05 WO PCT/US1989/003799 patent/WO1990002484A1/en active IP Right Grant
- 1989-09-05 KR KR1019900700948A patent/KR900701152A/ko not_active Application Discontinuation
- 1989-09-05 DE DE68929405T patent/DE68929405T2/de not_active Expired - Lifetime
- 1989-09-05 AT AT89910552T patent/ATE218797T1/de not_active IP Right Cessation
- 1989-09-05 JP JP1509842A patent/JPH04501801A/ja active Pending
- 1989-09-05 CA CA000610249A patent/CA1339307C/en not_active Expired - Fee Related
- 1989-09-05 EP EP89910552A patent/EP0433372B1/en not_active Expired - Lifetime
- 1989-09-05 IL IL91525A patent/IL91525A0/xx unknown
- 1989-09-05 AU AU43172/89A patent/AU634178B2/en not_active Expired
- 1989-09-06 NZ NZ230576A patent/NZ230576A/en unknown
-
1991
- 1991-03-06 DK DK039991A patent/DK39991A/da unknown
-
1995
- 1995-06-01 US US08/457,928 patent/US5679880A/en not_active Expired - Lifetime
- 1995-06-01 US US08/458,097 patent/US5654184A/en not_active Expired - Lifetime
- 1995-06-01 US US08/457,563 patent/US5686079A/en not_active Expired - Lifetime
-
1999
- 1999-07-14 JP JP11200841A patent/JP2000166411A/ja active Pending
Also Published As
Publication number | Publication date |
---|---|
EP0433372A1 (en) | 1991-06-26 |
AU4317289A (en) | 1990-04-02 |
DE68929405D1 (de) | 2002-07-18 |
US5686079A (en) | 1997-11-11 |
CA1339307C (en) | 1997-08-19 |
DE68929405T2 (de) | 2003-02-06 |
NZ230576A (en) | 1992-05-26 |
WO1990002484A1 (en) | 1990-03-22 |
US5654184A (en) | 1997-08-05 |
KR900701152A (ko) | 1990-12-01 |
AU634178B2 (en) | 1993-02-18 |
DK39991D0 (da) | 1991-03-06 |
JPH04501801A (ja) | 1992-04-02 |
JP2000166411A (ja) | 2000-06-20 |
EP0433372B1 (en) | 2002-06-12 |
US5679880A (en) | 1997-10-21 |
IL91525A0 (en) | 1990-04-29 |
ATE218797T1 (de) | 2002-06-15 |
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