DK395081A - N-( (4-(3-substitueret pyridyl)-piperazino)-alkyl) azeaspirodecandioner og fremgangsmaade til fremstilling deraf - Google Patents

N-( (4-(3-substitueret pyridyl)-piperazino)-alkyl) azeaspirodecandioner og fremgangsmaade til fremstilling deraf

Info

Publication number
DK395081A
DK395081A DK395081A DK395081A DK395081A DK 395081 A DK395081 A DK 395081A DK 395081 A DK395081 A DK 395081A DK 395081 A DK395081 A DK 395081A DK 395081 A DK395081 A DK 395081A
Authority
DK
Denmark
Prior art keywords
azeaspirodecandions
piperazino
procedures
alkyl
preparing
Prior art date
Application number
DK395081A
Other languages
English (en)
Other versions
DK154647C (da
DK154647B (da
Inventor
D L Temple
J P Yevich
W G Lobeck
Original Assignee
Bristol Myers Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bristol Myers Co filed Critical Bristol Myers Co
Publication of DK395081A publication Critical patent/DK395081A/da
Publication of DK154647B publication Critical patent/DK154647B/da
Application granted granted Critical
Publication of DK154647C publication Critical patent/DK154647C/da

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D401/00Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/14Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing three or more hetero rings
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/18Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Psychiatry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
DK395081A 1980-09-08 1981-09-07 Analogifremgangsmaade til fremstilling af n-oe(4-oe3-substitueret 2-pyridylaapiperazino)butylaaazaspirodecanforbindelser eller et farmaceutisk acceptabelt syreadditionssalt deraf DK154647C (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US06/184,677 US4305944A (en) 1980-09-08 1980-09-08 N-[(4-[3-cyano substituted pyridyl]piperazino)alkyl]-azaspirodecanediones
US18467780 1980-09-08

Publications (3)

Publication Number Publication Date
DK395081A true DK395081A (da) 1982-03-09
DK154647B DK154647B (da) 1988-12-05
DK154647C DK154647C (da) 1989-05-08

Family

ID=22677905

Family Applications (1)

Application Number Title Priority Date Filing Date
DK395081A DK154647C (da) 1980-09-08 1981-09-07 Analogifremgangsmaade til fremstilling af n-oe(4-oe3-substitueret 2-pyridylaapiperazino)butylaaazaspirodecanforbindelser eller et farmaceutisk acceptabelt syreadditionssalt deraf

Country Status (23)

Country Link
US (1) US4305944A (da)
JP (1) JPS5780381A (da)
AT (1) AT378192B (da)
AU (1) AU525584B2 (da)
BE (1) BE890265A (da)
CA (1) CA1196333A (da)
CH (1) CH649084A5 (da)
CY (1) CY1369A (da)
DE (1) DE3135523A1 (da)
DK (1) DK154647C (da)
FI (1) FI70580C (da)
FR (1) FR2489823A1 (da)
GB (1) GB2083474B (da)
GR (1) GR75756B (da)
HK (1) HK4388A (da)
IE (1) IE51548B1 (da)
KE (1) KE3721A (da)
LU (1) LU83616A1 (da)
NL (1) NL8104144A (da)
SE (1) SE442636B (da)
SG (1) SG29987G (da)
YU (2) YU42423B (da)
ZA (1) ZA816214B (da)

Families Citing this family (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4320131A (en) * 1981-03-16 1982-03-16 Mead Johnson & Company N-[(4-Phenyl-1,2,3,6-tetrahydropyridin-1-yl)alkylene]azaspiroalkanediones and N-[(4-hydroxy-4-phenylpiperidin-1-yl)alkylene]azaspiroalkanediones
US4507303A (en) * 1981-12-22 1985-03-26 Sumitomo Chemical Company, Limited Succinimide derivatives, compositions and method of use
US4361565A (en) * 1981-12-28 1982-11-30 Mead Johnson & Company 2-[4-[(4,4-Dialkyl-2,6-piperidinedion-1-yl)butyl]-1-piperazinyl]pyridines
US4524206A (en) * 1983-09-12 1985-06-18 Mead Johnson & Company 1-Heteroaryl-4-(2,5-pyrrolidinedion-1-yl)alkyl)piperazine derivatives
AT387773B (de) * 1983-09-12 1989-03-10 Bristol Myers Co Verfahren zur herstellung von 1-heteroaryl-4-((2,5-pyrrolidindion-1-yl)aklyl) iperazin-derivaten
US4656280A (en) * 1984-03-07 1987-04-07 E. I. Du Pont De Nemours And Company Radioiodinated dopamine receptor ligand
US4619930A (en) * 1985-01-16 1986-10-28 Bristol-Myers Company Antipsychotic cyclic imide derivatives of 2-(4-butylpiperazin-1-yl)pyridines, compositions and use
US4677104A (en) * 1985-05-06 1987-06-30 Bristol-Myers Company Antipsychotic fused-ring pyridinylpiperazine derivatives
US4812567A (en) * 1985-10-16 1989-03-14 American Home Products Corporation Polycyclic spiroimides with psychotropic activity
US4797488A (en) * 1987-04-03 1989-01-10 American Home Products Corporation Psychotropic polycyclic imides
US4748240A (en) * 1987-04-03 1988-05-31 American Home Products Corporation Psychotropic bicyclic imides
HU212301B (en) * 1989-04-28 1996-05-28 Alkaloida Vegyeszeti Gyar Process for producing buspirone
US5162321A (en) * 1989-12-20 1992-11-10 Adir Et Compagnie 1-naphthyl piperazines useful as 5-HT1A receptor ligands
US20040077605A1 (en) 2001-06-20 2004-04-22 Salvati Mark E. Fused heterocyclic succinimide compounds and analogs thereof, modulators of nuclear hormone receptor function

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3398151A (en) * 1966-02-01 1968-08-20 Mead Johnson & Co Azaspirodecanediones and azaspiroundecanediones
BE759371A (fr) * 1969-11-24 1971-05-24 Bristol Myers Co Azaspirodecanediones heterocycliques et procedes pour leur preparation
US3976776A (en) * 1972-12-06 1976-08-24 Mead Johnson & Company Tranquilizer process employing N-(heteroarcyclic)piperazinylalkylazaspiroalkanediones
US4182763A (en) * 1978-05-22 1980-01-08 Mead Johnson & Company Buspirone anti-anxiety method

Also Published As

Publication number Publication date
DE3135523A1 (de) 1982-06-16
AU525584B2 (en) 1982-11-11
HK4388A (en) 1988-01-29
KE3721A (en) 1987-04-30
YU213783A (en) 1984-02-29
LU83616A1 (fr) 1982-04-14
JPH0134226B2 (da) 1989-07-18
YU42423B (en) 1988-08-31
BE890265A (fr) 1982-03-08
DK154647C (da) 1989-05-08
CH649084A5 (de) 1985-04-30
FI812736L (fi) 1982-03-09
YU213881A (en) 1984-02-29
IE812069L (en) 1982-03-08
FI70580C (fi) 1986-09-24
ZA816214B (en) 1982-09-29
IE51548B1 (en) 1987-01-07
GB2083474B (en) 1984-05-31
DE3135523C2 (da) 1990-06-07
US4305944A (en) 1981-12-15
FI70580B (fi) 1986-06-06
FR2489823A1 (fr) 1982-03-12
GR75756B (da) 1984-08-02
JPS5780381A (en) 1982-05-19
NL8104144A (nl) 1982-04-01
CY1369A (en) 1987-08-07
CA1196333A (en) 1985-11-05
AU7502481A (en) 1982-03-18
SE8105341L (sv) 1982-03-09
ATA388181A (de) 1984-11-15
GB2083474A (en) 1982-03-24
FR2489823B1 (da) 1985-01-11
SE442636B (sv) 1986-01-20
AT378192B (de) 1985-06-25
DK154647B (da) 1988-12-05
SG29987G (en) 1987-07-17

Similar Documents

Publication Publication Date Title
DK433884D0 (da) 1-heteroaryl-4-((2,5-pyrrolidindion-1-yl)-alkyl)piperazin-derivater og fremgangsmaade til fremstilling deraf
DK304781A (da) Formdel og fremgansmaade til fremstolling heraf
DK108891A (da) 4-(4-phenyl-1-piperazinyl)phenoler og fremgangsmaade til fremstilling deraf
NO851897L (no) Lysfoelsomme forbindelser og fremgangsmaate for fremstilling derav.
NO803330L (no) Elektrolysoer og fremgangsmaate for elektrolysering
DK316784D0 (da) 1,2,4-triazol-3-on-derivater og fremgangsmaade til fremstilling deraf
DK574581A (da) Delta2-1,2,4-triazolin-5-on-derivater og fremgangsmaade til fremstilling heraf
NO855135L (no) Modifisert polyolefin og fremgangsmaate til fremstilling derav.
DK112984D0 (da) Naphthalenyl-og tetrahydronaphthalenylimidazoler og fremgangsmaade til fremstilling deraf
DK395081A (da) N-( (4-(3-substitueret pyridyl)-piperazino)-alkyl) azeaspirodecandioner og fremgangsmaade til fremstilling deraf
DK457581A (da) 4,5-polymethylen-4-isothiazolin-3-oner fremgangsmaade til deres fremstilling og deres anvendelse
DK178084D0 (da) 1,3-dihydro-6-methyl-7-hydrosyfuro-(3,4-c)-pyridinderivater og fremgangsmade til fremstilling deraf
DK163517C (da) Fremgangsmaade til fremstilling af 4'-epidaunorubicin og 3',4'-diepidaunorubicin
DK554485D0 (da) Geltandplejemiddel og fremgangsmaade til fremstilling deraf
DK79891A (da) 2,5-bis(2,2,2-trifluorethoxy)acetophenoner til brug som mellemprodukter og fremgangsmaade til fremstilling deraf
DK336779A (da) 1,2,3,5-tetrahydroimidazothienopyrimidin-2-oner og fremgangsmmaade til fremstilling heraf
DK567781A (da) Phenoxyalkoxysilaner og fremgangsmaade til fremstilling heraf
DK204884A (da) Gaerudtrykkelsesmedium, gaerorganisme transformeret dermed og fremgangsmaade til fremstilling af et for gaer heterologt protein
NO803451L (no) Nye 6alfa-fluor-9alfa-klor-prednisolon-17,21-diestere og fremgangsmaate ved fremstilling derav
DK281283D0 (da) 2,3-difluor-5-(trifluormethyl)-pyridin og fremgangsmader til fremstilling og anvendelse heraf
DK407080A (da) Substituerede piperidiner og fremgangsmaade til fremstilling deraf
DK528284A (da) 1-(2-aryl-2-halogen-1-ethenyl)-1h-azoler og fremgangsmaade til fremstilling deraf
DK621484A (da) Acylaminomitosaner og fremgangsmaade til fremstilling deraf
DK76981A (da) 5-(dihydroxyphenoxy)-1h-tetrazoler og fremgangsmaade til fremstilling deraf
DK271281A (da) Haardfeldt og fremgangsmaade til fremstilling deraf

Legal Events

Date Code Title Description
PBP Patent lapsed