DK3880649T3 - Fremgangsmåde til fremstilling af polyolbaserede estere af hydroxycarboxylsyrer - Google Patents

Fremgangsmåde til fremstilling af polyolbaserede estere af hydroxycarboxylsyrer Download PDF

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Publication number
DK3880649T3
DK3880649T3 DK19701816.1T DK19701816T DK3880649T3 DK 3880649 T3 DK3880649 T3 DK 3880649T3 DK 19701816 T DK19701816 T DK 19701816T DK 3880649 T3 DK3880649 T3 DK 3880649T3
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DK
Denmark
Prior art keywords
polyol
production
hydroxycarboxylic acids
based esters
esters
Prior art date
Application number
DK19701816.1T
Other languages
English (en)
Inventor
Dirk Lochmann
Sebastian Reyer
Michael Stehr
Original Assignee
Ketolipix Therapeutics Gmbh
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
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Publication date
Application filed by Ketolipix Therapeutics Gmbh filed Critical Ketolipix Therapeutics Gmbh
Application granted granted Critical
Publication of DK3880649T3 publication Critical patent/DK3880649T3/da

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    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C69/00Esters of carboxylic acids; Esters of carbonic or haloformic acids
    • C07C69/66Esters of carboxylic acids having esterified carboxylic groups bound to acyclic carbon atoms and having any of the groups OH, O—metal, —CHO, keto, ether, acyloxy, groups, groups, or in the acid moiety
    • C07C69/67Esters of carboxylic acids having esterified carboxylic groups bound to acyclic carbon atoms and having any of the groups OH, O—metal, —CHO, keto, ether, acyloxy, groups, groups, or in the acid moiety of saturated acids
    • C07C69/675Esters of carboxylic acids having esterified carboxylic groups bound to acyclic carbon atoms and having any of the groups OH, O—metal, —CHO, keto, ether, acyloxy, groups, groups, or in the acid moiety of saturated acids of saturated hydroxy-carboxylic acids
    • AHUMAN NECESSITIES
    • A23FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23LFOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
    • A23L33/00Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
    • A23L33/10Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof using additives
    • AHUMAN NECESSITIES
    • A23FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23LFOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
    • A23L33/00Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
    • A23L33/10Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof using additives
    • A23L33/115Fatty acids or derivatives thereof; Fats or oils
    • A23L33/12Fatty acids or derivatives thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/21Esters, e.g. nitroglycerine, selenocyanates
    • A61K31/215Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids
    • A61K31/22Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids of acyclic acids, e.g. pravastatin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • A61P3/02Nutrients, e.g. vitamins, minerals
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • A61P3/04Anorexiants; Antiobesity agents
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C67/00Preparation of carboxylic acid esters
    • C07C67/02Preparation of carboxylic acid esters by interreacting ester groups, i.e. transesterification
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C67/00Preparation of carboxylic acid esters
    • C07C67/03Preparation of carboxylic acid esters by reacting an ester group with a hydroxy group
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12PFERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P7/00Preparation of oxygen-containing organic compounds
    • C12P7/62Carboxylic acid esters
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12PFERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P7/00Preparation of oxygen-containing organic compounds
    • C12P7/62Carboxylic acid esters
    • C12P7/625Polyesters of hydroxy carboxylic acids

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Zoology (AREA)
  • Nutrition Science (AREA)
  • Wood Science & Technology (AREA)
  • Diabetes (AREA)
  • Obesity (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Hematology (AREA)
  • Mycology (AREA)
  • Biotechnology (AREA)
  • Polymers & Plastics (AREA)
  • Genetics & Genomics (AREA)
  • Microbiology (AREA)
  • General Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • Food Science & Technology (AREA)
  • Epidemiology (AREA)
  • Emergency Medicine (AREA)
  • Child & Adolescent Psychology (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Polyethers (AREA)
  • Polyesters Or Polycarbonates (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
  • Coloring Foods And Improving Nutritive Qualities (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Catalysts (AREA)
DK19701816.1T 2019-01-17 2019-01-23 Fremgangsmåde til fremstilling af polyolbaserede estere af hydroxycarboxylsyrer DK3880649T3 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP2019051117 2019-01-17
PCT/EP2019/051540 WO2020147979A1 (de) 2019-01-17 2019-01-23 Verfahren zur herstellung von polyolbasierten estern von hydroxycarbonsäuren

Publications (1)

Publication Number Publication Date
DK3880649T3 true DK3880649T3 (da) 2023-05-30

Family

ID=65234550

Family Applications (1)

Application Number Title Priority Date Filing Date
DK19701816.1T DK3880649T3 (da) 2019-01-17 2019-01-23 Fremgangsmåde til fremstilling af polyolbaserede estere af hydroxycarboxylsyrer

Country Status (10)

Country Link
US (1) US20230167046A1 (da)
EP (1) EP3880649B1 (da)
JP (2) JP7373572B2 (da)
CN (1) CN113329992B (da)
BR (1) BR112021013751A2 (da)
CY (1) CY1126064T1 (da)
DK (1) DK3880649T3 (da)
ES (1) ES2943142T3 (da)
FI (1) FI3880649T3 (da)
WO (1) WO2020147979A1 (da)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP3956286B1 (de) * 2019-06-12 2023-12-13 KetoLipix Therapeutics GmbH Verfahren zur herstellung von polyolbasierten estern, insbesondere polyglycerinestern, von hydroxycarbonsäuren
KR20230037576A (ko) 2020-07-13 2023-03-16 이오이 올레오 게엠베하 폴리카복실산과 가교된 3-하이드록시부티르산의 폴리글리세롤 에스테르의 제조 방법

Family Cites Families (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH0383950A (ja) * 1989-08-28 1991-04-09 Kanegafuchi Chem Ind Co Ltd グリセリド誘導体およびその製造法
ES2670413T3 (es) * 2003-06-03 2018-05-30 The United States Government As Represented By The Department Of Health And Human Services Suplementos nutricionales y composiciones terapéuticas que comprenden derivados de (R)-3-hidroxibutirato
US20070225252A1 (en) * 2004-07-23 2007-09-27 Gross Richard A Ketogenic Saccharides
EP2328858B1 (en) * 2008-08-21 2017-10-11 Oxford University Innovation Limited Drink comprising hydroxybutyrate ester and medical use thereof
KR101212177B1 (ko) 2010-04-08 2012-12-13 한국화학연구원 다수의 수산기를 포함하는 마이클 수용체, 이로부터 유도된 마이클 부가 생성물
GB201206192D0 (en) * 2012-04-05 2012-05-23 Tdeltas Ltd Ketone bodies and ketone body esters and for maintaining or improving muscle power output
GB2515603B (en) * 2013-03-14 2015-10-14 Isis Innovation Process for producing (R)-3-Hydroxybutyl (R)-3-Hydroxybutyrate
JP6401457B2 (ja) * 2013-12-20 2018-10-10 日清オイリオグループ株式会社 ポリグリセリンモノ脂肪酸エステルの製造方法
RU2679443C2 (ru) * 2014-10-21 2019-02-11 Университат Де Лес Ильес Балеарс Способ синтеза гидрокситриглицеридов и их применение для профилактики и лечения заболеваний
US10160834B2 (en) 2016-07-13 2018-12-25 Momentive Performance Materials Inc. Low viscosity polyorganosiloxanes comprising quaternary ammonium groups, methods for the production and the use thereof
US20180303821A1 (en) * 2017-04-24 2018-10-25 BraneQuest, Inc. Membrane active molecules
EP3880651A1 (de) * 2019-01-17 2021-09-22 IOI Oleo GmbH Verfahren zur herstellung von polyolbasierten estern von gegebenenfalls acylierten hydroxycarbonsäuren

Also Published As

Publication number Publication date
US20230167046A1 (en) 2023-06-01
JP2022518711A (ja) 2022-03-16
BR112021013751A2 (pt) 2021-09-21
JP7373572B2 (ja) 2023-11-02
ES2943142T3 (es) 2023-06-09
CN113329992B (zh) 2024-04-30
CN113329992A (zh) 2021-08-31
JP7538314B2 (ja) 2024-08-21
JP2024010045A (ja) 2024-01-23
EP3880649A1 (de) 2021-09-22
CY1126064T1 (el) 2023-11-15
EP3880649B1 (de) 2023-03-15
FI3880649T3 (fi) 2023-05-30
WO2020147979A1 (de) 2020-07-23

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