DK384576A - Heteroarylbenzoxepin-eddikesyrederivater, deres fremstilling og anvendelser - Google Patents

Heteroarylbenzoxepin-eddikesyrederivater, deres fremstilling og anvendelser

Info

Publication number
DK384576A
DK384576A DK384576A DK384576A DK384576A DK 384576 A DK384576 A DK 384576A DK 384576 A DK384576 A DK 384576A DK 384576 A DK384576 A DK 384576A DK 384576 A DK384576 A DK 384576A
Authority
DK
Denmark
Prior art keywords
heteroarylbenzoxepine
acquiric
manufacture
acid derivatives
derivatives
Prior art date
Application number
DK384576A
Other languages
Danish (da)
English (en)
Inventor
A R Mcfadden
D E Aultz
Original Assignee
Hoechst Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hoechst Ag filed Critical Hoechst Ag
Publication of DK384576A publication Critical patent/DK384576A/da

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D213/00Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/60Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D213/78Carbon atoms having three bonds to hetero atoms, with at the most one bond to halogen, e.g. ester or nitrile radicals
    • C07D213/79Acids; Esters
    • C07D213/80Acids; Esters in position 3
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D207/00Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D207/02Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D207/30Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members
    • C07D207/34Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D307/00Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
    • C07D307/02Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings
    • C07D307/34Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D307/56Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D307/68Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D333/00Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom
    • C07D333/02Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings
    • C07D333/04Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom
    • C07D333/26Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D333/38Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D491/00Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
    • C07D491/02Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains two hetero rings
    • C07D491/04Ortho-condensed systems
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D493/00Heterocyclic compounds containing oxygen atoms as the only ring hetero atoms in the condensed system
    • C07D493/02Heterocyclic compounds containing oxygen atoms as the only ring hetero atoms in the condensed system in which the condensed system contains two hetero rings
    • C07D493/04Ortho-condensed systems
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D495/00Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms
    • C07D495/02Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
    • C07D495/04Ortho-condensed systems

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Heterocyclic Compounds Containing Sulfur Atoms (AREA)
  • Furan Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Pyridine Compounds (AREA)
  • Pyrrole Compounds (AREA)
DK384576A 1975-08-26 1976-08-25 Heteroarylbenzoxepin-eddikesyrederivater, deres fremstilling og anvendelser DK384576A (da)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US05/607,926 US4025640A (en) 1975-08-26 1975-08-26 Oxothienobenzoxepin-acetic acids, precursors and derivatives thereof

Publications (1)

Publication Number Publication Date
DK384576A true DK384576A (da) 1977-02-27

Family

ID=24434282

Family Applications (1)

Application Number Title Priority Date Filing Date
DK384576A DK384576A (da) 1975-08-26 1976-08-25 Heteroarylbenzoxepin-eddikesyrederivater, deres fremstilling og anvendelser

Country Status (25)

Country Link
US (7) US4025640A (no)
JP (1) JPS5227764A (no)
AT (1) AT359505B (no)
AU (1) AU504461B2 (no)
BE (1) BE845551A (no)
CA (1) CA1068275A (no)
CH (1) CH624408A5 (no)
DE (1) DE2637110C3 (no)
DK (1) DK384576A (no)
ES (1) ES450881A1 (no)
FI (1) FI62093C (no)
FR (2) FR2346004A1 (no)
GB (2) GB1563841A (no)
GR (1) GR60832B (no)
HU (2) HU173465B (no)
IE (1) IE43940B1 (no)
IL (2) IL50347A (no)
IT (1) IT1064977B (no)
LU (1) LU75650A1 (no)
MX (1) MX4236E (no)
NL (1) NL7609292A (no)
NO (1) NO145139C (no)
PT (1) PT65513B (no)
SE (1) SE430161B (no)
ZA (1) ZA765112B (no)

Families Citing this family (24)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4025640A (en) * 1975-08-26 1977-05-24 American Hoechst Corporation Oxothienobenzoxepin-acetic acids, precursors and derivatives thereof
US4104280A (en) * 1977-02-04 1978-08-01 Syntex (U.S.A.) Inc. Dibenzo [b.f]thiepin and dibenzo[b.f]oxepin derivatives
US4130654A (en) * 1978-01-30 1978-12-19 Syntex (U.S.A.) Inc. Novel 4-(8X-6,11-dihydrodibenzo-[b.e.]-thiepin-11-one-3-yl)-4-oxobutyric acids, methods of preparation, compositions and uses thereof
JPS54115388A (en) * 1978-03-01 1979-09-07 Nippon Chemiphar Co Ltd Acetic acid derivative and its preparation
JPS54147304U (no) * 1978-04-04 1979-10-13
US4211877A (en) * 1979-02-13 1980-07-08 American Hoechst Corporation Method of preparation of isopropyl 4,10-dihydro-10-oxothieno[3,2-c][1]benzoxepin-8-acetate
DE3125374A1 (de) * 1981-06-27 1983-01-13 Hoechst Ag, 6000 Frankfurt Verfahren zur herstellung von heteroaryl- und dibenzoxepinalkansaeuren
AU8509882A (en) * 1981-06-30 1983-01-06 Merck & Co., Inc. Tricyclic derivatives of substituted pyrrole acids
US4496580A (en) * 1981-07-23 1985-01-29 Hoechst-Roussel Pharmaceuticals Inc. Oxothienobenzoxepins
US4560701A (en) * 1981-07-23 1985-12-24 Hoechst-Roussel Pharmaceuticals Inc. Oxothienobenzoxepins, medicinal use, and process for the preparation thereof
US4477465A (en) * 1983-03-10 1984-10-16 Hoechst-Roussel Pharmaceuticals Inc. Substituted 4,10-dihydro-10-oxothieno benzoxepins
US4514411A (en) * 1983-03-10 1985-04-30 Hoechst-Roussel Pharmaceuticals Inc. Substituted 4,10-dihydro-10-oxothieno benzoxepins
US4751238A (en) * 1983-03-10 1988-06-14 Hoechst-Roussel Pharmaceuticals, Inc. Substituted alkyl amine derivatives of 6,11-dihydro-11-oxodibenz[b,e]oxepins
EP0118867A3 (en) * 1983-03-10 1984-12-05 Hoechst-Roussel Pharmaceuticals Incorporated Substituted 4,10-dihydro-10-oxothieno benzoxepins, a method of preparing the same and intermediate thereof and their use as medicaments
US5260319A (en) * 1989-12-26 1993-11-09 Hoechst-Roussel Pharmaceuticals Incorporated Thienobenzoxepins and naphthothiophenes
US5139796A (en) * 1991-06-28 1992-08-18 Wm. Wrigley Jr. Company Tocopherol mixture for use as a mint oil antioxidant in chewing gum
US5200213A (en) * 1991-08-12 1993-04-06 Wm. Wrigley Jr. Company Gum base containing tocopherol
US5132121A (en) * 1991-08-12 1992-07-21 Wm. Wrigley Jr. Company Gum base containing tocopherol
DE60234057D1 (de) 2001-07-25 2009-11-26 Raptor Pharmaceutical Inc Zusammensetzungen und verfahren zur modulation des transports durch die blut-hirn-schranke
EP2392258B1 (en) 2005-04-28 2014-10-08 Proteus Digital Health, Inc. Pharma-informatics system
US8795627B2 (en) 2007-03-21 2014-08-05 Raptor Pharmaceuticals Inc. Treatment of liver disorders by administration of RAP conjugates
AU2010216512B2 (en) 2009-02-20 2016-06-30 2-Bbb Medicines B.V. Glutathione-based drug delivery system
WO2010129819A2 (en) 2009-05-06 2010-11-11 Laboratory Skin Care, Inc. Dermal delivery compositions comprising active agent-calcium phosphate particle complexes and methods of using the same
US20120077778A1 (en) 2010-09-29 2012-03-29 Andrea Bourdelais Ladder-Frame Polyether Conjugates

Family Cites Families (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CH83A (fr) * 1888-11-17 1889-01-10 Fontainemelon Horlogerie Perfectionnements apportés à la construction des montres de tous calibres
CH469729A (de) * 1963-08-31 1969-03-15 Spofa Vereinigte Pharma Werke Verfahren zur Herstellung von neuen 4,9-Dihydrothieno-(2,3-b)-benzo-(e)-thiepinderivaten
US3883551A (en) * 1969-08-25 1975-05-13 Little Inc A Thienobenzopyrans and thiopyranobenzopyrans
US3888946A (en) * 1971-03-17 1975-06-10 Little Inc A Pyrano benzopyrans
US3960871A (en) * 1971-12-27 1976-06-01 Sharps Associates Esters of thienobenzopyrans and thiopyranobenzopyrans
US3991194A (en) * 1971-12-27 1976-11-09 Sharps Associates Heterocyclic esters of benzopyranopyridines
DK131631C (da) * 1972-04-07 1976-01-12 Sandoz Ag Analogifremgangsmade til fremstilling af 4-oxo-benzo(4,5)cyclohepta(1,2-b)thiophen-2-eddikesyreforbindelser
GB1403487A (en) * 1972-07-21 1975-08-28 Yoshitomi Pharmaceutical Heterocyclic substituted alkanoic acids and derivatives
US3825574A (en) * 1972-12-04 1974-07-23 Warner Lambert Co Process for preparing substituted chromone-3-carbonitriles,carboxamides and carboxylic acids
US3862143A (en) * 1972-12-04 1975-01-21 Warner Lambert Co Substituted chromone-3-carbonitriles, carboxamides and carboxylic acids
US3895034A (en) * 1973-08-29 1975-07-15 Sharps Ass 1 OR 2-Mono and dialkyl substituted thienobenzopyrans
US3946111A (en) * 1973-08-29 1976-03-23 Sharps Associates Pharmaceutical compositions containing 1 or 2-mono and dialkyl substituted thienobenzopyrans and pharmacological uses thereof
CH597228A5 (no) * 1973-09-04 1978-03-31 Yoshitomi Pharmaceutical
DK467274A (no) * 1973-09-13 1975-05-12 Sandoz Ag
US3952025A (en) * 1974-08-26 1976-04-20 American Hoechst Corporation Substituted 2-phenyl-4,6,7,8-tetrahydrofuro and 1,4,5,6,7,8-hexahydropyrrolo[3,2,-c]azepines
US4025640A (en) * 1975-08-26 1977-05-24 American Hoechst Corporation Oxothienobenzoxepin-acetic acids, precursors and derivatives thereof
US4028383A (en) * 1975-09-08 1977-06-07 Warner-Lambert Company Indolopyrones having antiallergic activity

Also Published As

Publication number Publication date
ES450881A1 (es) 1977-12-16
US4025640A (en) 1977-05-24
GB1563842A (en) 1980-04-02
HU173465B (hu) 1979-05-28
IL58864A0 (en) 1980-03-31
FR2351972A1 (fr) 1977-12-16
FR2346004A1 (fr) 1977-10-28
FI62093C (fi) 1982-11-10
ATA630876A (de) 1980-04-15
US4117152A (en) 1978-09-26
FI62093B (fi) 1982-07-30
US4107321A (en) 1978-08-15
IE43940B1 (en) 1981-07-01
JPS5227764A (en) 1977-03-02
GB1563841A (en) 1980-04-02
HU174164B (hu) 1979-11-28
NO145139C (no) 1982-01-20
NO145139B (no) 1981-10-12
PT65513B (en) 1978-05-10
US4124713A (en) 1978-11-07
AU1715176A (en) 1978-03-02
NO762929L (no) 1977-03-01
FI762422A (no) 1977-02-27
FR2346004B1 (no) 1979-09-07
DE2637110B2 (de) 1979-10-11
FR2351972B1 (no) 1981-12-24
MX4236E (es) 1982-02-24
CH624408A5 (no) 1981-07-31
AU504461B2 (en) 1979-10-18
GR60832B (en) 1978-08-31
US4081457A (en) 1978-03-28
US4107177A (en) 1978-08-15
IL50347A (en) 1982-04-30
DE2637110C3 (de) 1980-07-24
PT65513A (en) 1976-09-01
SE430161B (sv) 1983-10-24
IL50347A0 (en) 1976-10-31
NL7609292A (nl) 1977-03-01
IT1064977B (it) 1985-02-25
US4101559A (en) 1978-07-18
ZA765112B (en) 1977-08-31
LU75650A1 (no) 1977-04-27
SE7609390L (sv) 1977-02-27
IE43940L (en) 1977-02-26
DE2637110A1 (de) 1977-03-17
CA1068275A (en) 1979-12-18
BE845551A (fr) 1977-02-28
AT359505B (de) 1980-11-10

Similar Documents

Publication Publication Date Title
DK384576A (da) Heteroarylbenzoxepin-eddikesyrederivater, deres fremstilling og anvendelser
DK248476A (da) Cyaneddikesyreanilid-derivater samt deres fremstilling og anvendelse
SE7612365L (sv) L-fenyl-2-oxo-pyrrolidin-4-karbonsyraderivat
NL7606654A (nl) Imidylbenzeencarbonzuurderivaten.
SE7608840L (sv) Prostansyraderivat
DK463776A (da) Garvede thrombocyter, deres fremstilling og anvendelse
DK297076A (da) Phenyleddikesyrederivater og fremgangsmade til deres fremstilling
NL7606655A (nl) Imidylbenzeendi- en -tricarbonzuurderivaten.
DK148576A (da) Fenylalkankarbonsyrederivater og fremgangsmade til deres fremstilling
NL7613659A (nl) Hydroxybenzylmalonzuurderivaten.
DK391075A (da) 7-amino-3-cephem-4-carboxylsyrederivater og deres fremstilling
NL7609137A (nl) Fenoxyalkylcarbonzuurderivaten.
DK19777A (da) Thiazolidinderivater, deres fremstilling og anvendelser
DK411976A (da) Benzopyranderivater og deres fremstilling og anvendelse
DK526976A (da) Picolinsyrerivater og fremgangsmade til fremstilling heraf
DK191375A (da) Isoflavonderivater, deres fremstilling og anvendelse
DK411876A (da) Benzopyranderivater og deres fremstilling og anvendelse
DK2476A (da) Morpholinderivater og deres fremstilling
SE7601566L (sv) Prostansyraderivat
DK589775A (da) Dianhydrohexitoler, deres fremstilling og anvendelse
DK523176A (da) Substituerede tetraalkylpiperidin-4-oximer deres fremstilling og anvendelse
DK307776A (da) Morpholinderivater og deres fremstilling
DK501976A (da) Imidazolidindionderivater deres fremstilling og anvendelse
DK51677A (da) Benzamider, deres fremstilling og anvendelser
NL7602107A (nl) Prostaanzuurderivaten.

Legal Events

Date Code Title Description
ATS Application withdrawn