DK3801515T3 - 5 [[4 [2 [5 (1 hydroxyethyl)pyridin 2 yl]ethoxy]phenyl]methyl] 1,3 thiazolidin 2,4 dion og dets salte til anvendelse i behandlingen af mitokondriesygdomme - Google Patents
5 [[4 [2 [5 (1 hydroxyethyl)pyridin 2 yl]ethoxy]phenyl]methyl] 1,3 thiazolidin 2,4 dion og dets salte til anvendelse i behandlingen af mitokondriesygdomme Download PDFInfo
- Publication number
- DK3801515T3 DK3801515T3 DK19742480.7T DK19742480T DK3801515T3 DK 3801515 T3 DK3801515 T3 DK 3801515T3 DK 19742480 T DK19742480 T DK 19742480T DK 3801515 T3 DK3801515 T3 DK 3801515T3
- Authority
- DK
- Denmark
- Prior art keywords
- mitochondral
- thiazolidine
- dione
- pyridin
- ethoxy
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A61K31/4427—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems
- A61K31/4439—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems containing a five-membered ring with nitrogen as a ring hetero atom, e.g. omeprazole
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0053—Mouth and digestive tract, i.e. intraoral and peroral administration
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P21/00—Drugs for disorders of the muscular or neuromuscular system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
Landscapes
- Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Medicinal Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Neurology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Epidemiology (AREA)
- Neurosurgery (AREA)
- Biomedical Technology (AREA)
- Hospice & Palliative Care (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Physical Education & Sports Medicine (AREA)
- Psychiatry (AREA)
- Ophthalmology & Optometry (AREA)
- Nutrition Science (AREA)
- Physiology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP18382397 | 2018-06-06 | ||
| PCT/IB2019/054696 WO2019234664A1 (en) | 2018-06-06 | 2019-06-06 | 5-[[4-[2-[5-(1-hydroxyethyl)pyridin-2-yl]ethoxy]phenyl]methyl]-1,3-thiazolidine-2,4-dione and its salts for use in the treatment of mitochondrial diseases |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| DK3801515T3 true DK3801515T3 (da) | 2025-04-28 |
Family
ID=62716008
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DK19742480.7T DK3801515T3 (da) | 2018-06-06 | 2019-06-06 | 5 [[4 [2 [5 (1 hydroxyethyl)pyridin 2 yl]ethoxy]phenyl]methyl] 1,3 thiazolidin 2,4 dion og dets salte til anvendelse i behandlingen af mitokondriesygdomme |
Country Status (13)
| Country | Link |
|---|---|
| US (2) | US11957670B2 (https=) |
| EP (2) | EP4545142A3 (https=) |
| JP (1) | JP7376934B2 (https=) |
| DK (1) | DK3801515T3 (https=) |
| ES (1) | ES3028538T3 (https=) |
| FI (1) | FI3801515T3 (https=) |
| HR (1) | HRP20250591T1 (https=) |
| HU (1) | HUE071482T2 (https=) |
| LT (1) | LT3801515T (https=) |
| PL (1) | PL3801515T3 (https=) |
| PT (1) | PT3801515T (https=) |
| SI (1) | SI3801515T1 (https=) |
| WO (1) | WO2019234664A1 (https=) |
Families Citing this family (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20130158077A1 (en) | 2011-12-19 | 2013-06-20 | Ares Trading S.A. | Pharmaceutical compositions |
| EP3917508A4 (en) | 2019-01-28 | 2022-12-21 | Mitochondria Emotion, Inc. | EAAT2 ACTIVATORS AND METHODS OF USE THEREOF |
| CA3127453A1 (en) | 2019-01-28 | 2020-08-06 | Mitochondria Emotion, Inc. | Trans-4-hydroxycyclohexyl phenyl amide mitofusin activators and methods of use thereof |
Family Cites Families (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| AU2012205798B2 (en) | 2011-01-10 | 2016-02-25 | Takeda Pharmaceutical Company Limited | Methods and drug products for treating Alzheimer's disease |
| EP3013371A4 (en) | 2013-06-26 | 2017-04-26 | Rett Syndrome Research Trust | Rett syndrome and treatments therefore |
| US10188639B2 (en) | 2014-01-15 | 2019-01-29 | Deuterx, Llc | Methods of treating neurological, metabolic, and other disorders using enantiopure deuterium-enriched pioglitazone |
| EP3125888B1 (en) | 2014-04-02 | 2018-05-23 | Minoryx Therapeutics S.L. | 2,4-thiazolidinedione derivatives in the treatment of central nervous system disorders |
| WO2017057587A1 (ja) | 2015-09-30 | 2017-04-06 | 株式会社ニコン | 露光装置、フラットパネルディスプレイの製造方法、及びデバイス製造方法 |
| WO2017083739A1 (en) * | 2015-11-13 | 2017-05-18 | The Trustees Of Columbia University In The City Of New York | A method for predicting a subject's response to valproic acid therapy |
| CN106202285A (zh) | 2016-06-30 | 2016-12-07 | 北京百度网讯科技有限公司 | 搜索结果展示方法和装置 |
| EP3548026B1 (en) | 2016-12-01 | 2021-01-20 | Minoryx Therapeutics S.L. | 5-[[4-[2-[5-(1-hydroxyethyl)pyridin-2-yl]ethoxy]phenyl]methyl]-1,3-thiazolidine-2,4-dione for treating nonalcoholic fatty liver disease |
| EP3559010B1 (en) | 2016-12-23 | 2022-06-08 | Minoryx Therapeutics S.L. | Process for preparing 5-[[4-[2-[5-(1-hydroxyethyl)-2-pyridinyl]ethoxy]phenyl]methyl]-2,4-thiazolidinedione and salts thereof |
| EA202092954A1 (ru) | 2018-06-06 | 2021-04-08 | Минорикс Терапьютикс С.Л. | Применение 5-[4-[2-[5-ацетилпиридин-2-ил]этокси]бензил]-1,3-тиазолидин-2,4-диона и его солей |
| BR112020024917A2 (pt) | 2018-06-06 | 2021-03-09 | Minoryx Therapeutics S.L. | Método de administrar uma quantidade terapeuticamente eficaz de 5-[[4-[2-[5-(1-hidroxietil)piridin-2-il]etoxi]fenil]metil]-1,3-tiazolidina-2,4-diona |
-
2019
- 2019-06-06 FI FIEP19742480.7T patent/FI3801515T3/fi active
- 2019-06-06 EP EP25162244.5A patent/EP4545142A3/en active Pending
- 2019-06-06 WO PCT/IB2019/054696 patent/WO2019234664A1/en not_active Ceased
- 2019-06-06 US US16/972,375 patent/US11957670B2/en active Active
- 2019-06-06 SI SI201930937T patent/SI3801515T1/sl unknown
- 2019-06-06 ES ES19742480T patent/ES3028538T3/es active Active
- 2019-06-06 HR HRP20250591TT patent/HRP20250591T1/hr unknown
- 2019-06-06 PL PL19742480.7T patent/PL3801515T3/pl unknown
- 2019-06-06 HU HUE19742480A patent/HUE071482T2/hu unknown
- 2019-06-06 EP EP19742480.7A patent/EP3801515B1/en active Active
- 2019-06-06 JP JP2020567815A patent/JP7376934B2/ja active Active
- 2019-06-06 DK DK19742480.7T patent/DK3801515T3/da active
- 2019-06-06 PT PT197424807T patent/PT3801515T/pt unknown
- 2019-06-06 LT LTEPPCT/IB2019/054696T patent/LT3801515T/lt unknown
-
2024
- 2024-04-12 US US18/633,922 patent/US20250064791A1/en active Pending
Also Published As
| Publication number | Publication date |
|---|---|
| PT3801515T (pt) | 2025-06-11 |
| JP2021527049A (ja) | 2021-10-11 |
| EP3801515B1 (en) | 2025-04-09 |
| ES3028538T3 (en) | 2025-06-19 |
| HUE071482T2 (hu) | 2025-08-28 |
| HRP20250591T1 (hr) | 2025-07-04 |
| EP4545142A3 (en) | 2025-06-11 |
| FI3801515T3 (fi) | 2025-05-27 |
| EP4545142A2 (en) | 2025-04-30 |
| US20210228559A1 (en) | 2021-07-29 |
| SI3801515T1 (sl) | 2025-07-31 |
| JP7376934B2 (ja) | 2023-11-09 |
| US11957670B2 (en) | 2024-04-16 |
| PL3801515T3 (pl) | 2025-07-14 |
| WO2019234664A1 (en) | 2019-12-12 |
| LT3801515T (lt) | 2025-06-10 |
| US20250064791A1 (en) | 2025-02-27 |
| EP3801515A1 (en) | 2021-04-14 |
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