DK3860598T3 - Vemurafenib og salte heraf til anvendelse til behandling af enterovirusinfektioner - Google Patents

Vemurafenib og salte heraf til anvendelse til behandling af enterovirusinfektioner Download PDF

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Publication number
DK3860598T3
DK3860598T3 DK19790573.0T DK19790573T DK3860598T3 DK 3860598 T3 DK3860598 T3 DK 3860598T3 DK 19790573 T DK19790573 T DK 19790573T DK 3860598 T3 DK3860598 T3 DK 3860598T3
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Denmark
Prior art keywords
vemurafenib
salts
treatment
enterovirus infections
enterovirus
Prior art date
Application number
DK19790573.0T
Other languages
English (en)
Inventor
Varpu Marjomäki
Mira Laajala
Mari Martikainen
Original Assignee
Jyvaeskylaen Yliopisto
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Publication of DK3860598T3 publication Critical patent/DK3860598T3/da

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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/4353Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems
    • A61K31/437Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems the heterocyclic ring system containing a five-membered ring having nitrogen as a ring hetero atom, e.g. indolizine, beta-carboline
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/0053Mouth and digestive tract, i.e. intraoral and peroral administration
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/20Pills, tablets, discs, rods
    • A61K9/2004Excipients; Inactive ingredients
    • A61K9/2009Inorganic compounds
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/20Pills, tablets, discs, rods
    • A61K9/2004Excipients; Inactive ingredients
    • A61K9/2013Organic compounds, e.g. phospholipids, fats
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/20Pills, tablets, discs, rods
    • A61K9/2004Excipients; Inactive ingredients
    • A61K9/2022Organic macromolecular compounds
    • A61K9/205Polysaccharides, e.g. alginate, gums; Cyclodextrin
    • A61K9/2054Cellulose; Cellulose derivatives, e.g. hydroxypropyl methylcellulose
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12Antivirals
    • A61P31/14Antivirals for RNA viruses
    • A61P31/16Antivirals for RNA viruses for influenza or rhinoviruses
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02ATECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A50/00TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
    • Y02A50/30Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Virology (AREA)
  • Molecular Biology (AREA)
  • Organic Chemistry (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pulmonology (AREA)
  • Nutrition Science (AREA)
  • Physiology (AREA)
  • Inorganic Chemistry (AREA)
  • Biophysics (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
DK19790573.0T 2018-10-03 2019-10-03 Vemurafenib og salte heraf til anvendelse til behandling af enterovirusinfektioner DK3860598T3 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
FI20185830 2018-10-03
PCT/FI2019/050712 WO2020070390A1 (en) 2018-10-03 2019-10-03 Vemurafenib and salts thereof for use in the treatment of enteroviral infections

Publications (1)

Publication Number Publication Date
DK3860598T3 true DK3860598T3 (da) 2023-10-16

Family

ID=68296508

Family Applications (1)

Application Number Title Priority Date Filing Date
DK19790573.0T DK3860598T3 (da) 2018-10-03 2019-10-03 Vemurafenib og salte heraf til anvendelse til behandling af enterovirusinfektioner

Country Status (5)

Country Link
US (1) US20210244716A1 (da)
EP (1) EP3860598B1 (da)
DK (1) DK3860598T3 (da)
FI (1) FI3860598T3 (da)
WO (1) WO2020070390A1 (da)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP4153174A1 (en) * 2020-05-19 2023-03-29 Board of Regents, The University of Texas System Methods for the treatment of pancreatitis and prevention of pancreatic cancer

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1994018960A1 (en) 1993-02-26 1994-09-01 Schering Corporation Use of 2-chloro-1-[[4-[(2,6-dichlorophenoxy)methyl]-phenyl]methoxy]-4-methoxy-benzene for the selective treatment of enteroviral infections in humans
MY153898A (en) 2005-06-22 2015-04-15 Plexxikon Inc Compounds and methods for kinase modulation, and indications therefor
EP2585067B1 (en) 2010-06-25 2017-08-09 Biota Scientific Management Pty Ltd Compound for the treatment of enteroviruses
EA201590041A1 (ru) 2012-07-03 2015-04-30 Ратиофарм Гмбх Твердая форма холиновой соли вемурафениба
JP6294889B2 (ja) 2012-10-08 2018-03-14 アトリバ セラピューティクス ゲーエムベーハー ウイルス疾患の処置におけるmek阻害物質
JP2016512518A (ja) * 2013-03-14 2016-04-28 ラシオファルム ゲーエムベーハー ベムラフェニブ塩酸塩の固体形態
WO2016073421A1 (en) * 2014-11-03 2016-05-12 Dispersol Technologies, Llc Improved formulations of vemurafenib and methods of making the same
EP3223817A4 (en) 2014-11-29 2018-05-30 Shilpa Medicare Limited Substantially pure vemurafenib and its salts
CZ2015257A3 (cs) 2015-04-16 2016-10-26 Zentiva, K.S. Způsob pro zmenšování velikosti částic bromidu [(3R)-1-(3-fenoxypropyl)chinuklidin-1-ium-3-yl] 2-hydroxy-2,2-bis(2-thienyl)acetátu
EP3419980A4 (en) 2016-02-26 2019-07-03 The Board of Trustees of the Leland Stanford Junior University INHIBITORS OF PI-KINASE WITH ANTI-INFECTIOUS ACTIVITY
WO2018002415A1 (en) 2016-07-01 2018-01-04 Fermion Oy New processes for the preparation of vemurafenib

Also Published As

Publication number Publication date
WO2020070390A1 (en) 2020-04-09
FI3860598T3 (fi) 2023-10-26
EP3860598A1 (en) 2021-08-11
EP3860598B1 (en) 2023-09-06
US20210244716A1 (en) 2021-08-12

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