DK37782A - Fremgangsmaade til fremstilling af 17alfa-hydroxy-17beta-hydroxyacetylsteroider - Google Patents

Fremgangsmaade til fremstilling af 17alfa-hydroxy-17beta-hydroxyacetylsteroider Download PDF

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Publication number
DK37782A
DK37782A DK37782A DK37782A DK37782A DK 37782 A DK37782 A DK 37782A DK 37782 A DK37782 A DK 37782A DK 37782 A DK37782 A DK 37782A DK 37782 A DK37782 A DK 37782A
Authority
DK
Denmark
Prior art keywords
carbon atoms
hydroxyacetyl
steroids
hydroxy
17alfa
Prior art date
Application number
DK37782A
Other languages
Danish (da)
English (en)
Inventor
L Nedelec
V Torelli
M Hardy
Original Assignee
Roussel Uclaf
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Roussel Uclaf filed Critical Roussel Uclaf
Publication of DK37782A publication Critical patent/DK37782A/da

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Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07JSTEROIDS
    • C07J41/00Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring
    • C07J41/0033Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring not covered by C07J41/0005
    • C07J41/005Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring not covered by C07J41/0005 the 17-beta position being substituted by an uninterrupted chain of only two carbon atoms, e.g. pregnane derivatives
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07JSTEROIDS
    • C07J5/00Normal steroids containing carbon, hydrogen, halogen or oxygen, substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane and substituted in position 21 by only one singly bound oxygen atom, i.e. only one oxygen bound to position 21 by a single bond
    • C07J5/0046Normal steroids containing carbon, hydrogen, halogen or oxygen, substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane and substituted in position 21 by only one singly bound oxygen atom, i.e. only one oxygen bound to position 21 by a single bond substituted in position 17 alfa
    • C07J5/0053Normal steroids containing carbon, hydrogen, halogen or oxygen, substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane and substituted in position 21 by only one singly bound oxygen atom, i.e. only one oxygen bound to position 21 by a single bond substituted in position 17 alfa not substituted in position 16

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Steroid Compounds (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
DK37782A 1981-01-29 1982-01-28 Fremgangsmaade til fremstilling af 17alfa-hydroxy-17beta-hydroxyacetylsteroider DK37782A (da)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR8101688A FR2498607A1 (fr) 1981-01-29 1981-01-29 Nouveau procede de preparation de 17a-hydroxy 17b-hydroxyacetyle steroides, produits intermediaires correspondants et produits finals obtenus

Publications (1)

Publication Number Publication Date
DK37782A true DK37782A (da) 1982-07-30

Family

ID=9254633

Family Applications (1)

Application Number Title Priority Date Filing Date
DK37782A DK37782A (da) 1981-01-29 1982-01-28 Fremgangsmaade til fremstilling af 17alfa-hydroxy-17beta-hydroxyacetylsteroider

Country Status (10)

Country Link
US (1) US4565656A (pt)
EP (1) EP0058097B1 (pt)
JP (1) JPS57144299A (pt)
AT (1) ATE8638T1 (pt)
DE (1) DE3260408D1 (pt)
DK (1) DK37782A (pt)
FI (1) FI77462C (pt)
FR (1) FR2498607A1 (pt)
HU (1) HU187843B (pt)
PT (1) PT74343B (pt)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0123736A1 (en) * 1983-04-29 1984-11-07 Gist-Brocades N.V. New process for the preparation of 21-hydroxy-20-keto-delta 16-steroids and new intermediate compounds formed in this process
US4910191A (en) * 1988-06-28 1990-03-20 Merrell Dow Pharmaceuticals Inc. 19-substituted progesterone derivatives useful as 19-hydroxylase inhibitors
US5202316A (en) * 1989-03-22 1993-04-13 Roussel Uclaf N,N,N',N'-6-(1-piperazinyl)-2,5-pyridinediamines
FR2683530B1 (fr) * 1991-11-08 1994-01-21 Roussel Uclaf Nouveau procede de preparation de derives 20-oxo 17 alpha, 21-dihydroxyles du pregnane et nouveaux intermediaires.
FR2719588B1 (fr) * 1994-05-03 1996-06-07 Roussel Uclaf Nouveau procédé de préparation de la substance "S" et nouveaux intermédiaires.

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3793350A (en) * 1971-10-01 1974-02-19 Syntex Corp Process for preparing 17alpha,21-dihydroxy-20-keto-pregnanes,derivatives and intermediates thereof
DE2603266A1 (de) * 1976-01-29 1977-08-11 Hoechst Ag 17-hydroxyacetylsteroide und verfahren zu ihrer herstellung
DE2655104A1 (de) * 1976-12-04 1978-06-08 Hoechst Ag Verfahren zur herstellung von 17alpha-hydroxy-21-acetoxy-progesteron
DE2704130A1 (de) * 1977-01-28 1978-08-10 Schering Ag Verfahren zur herstellung von 17 beta- hydroxy-20-alkoxy-pregnan-21-saeure-derivaten
FR2462445A1 (fr) * 1979-07-31 1981-02-13 Roussel Uclaf Nouveaux derives 17-/(hydroxymethyl) (formamido) methylene/steroides, leur procede de preparation et leur application a l'introduction de la chaine laterale hydroxyacetyle

Also Published As

Publication number Publication date
FR2498607A1 (fr) 1982-07-30
FI820240L (fi) 1982-07-30
FI77462C (fi) 1989-03-10
EP0058097A3 (en) 1982-10-27
EP0058097A2 (fr) 1982-08-18
HU187843B (en) 1986-02-28
FI77462B (fi) 1988-11-30
PT74343A (fr) 1982-02-01
JPH036158B2 (pt) 1991-01-29
JPS57144299A (en) 1982-09-06
US4565656A (en) 1986-01-21
ATE8638T1 (de) 1984-08-15
DE3260408D1 (en) 1984-08-30
EP0058097B1 (fr) 1984-07-25
PT74343B (fr) 1984-05-30
FR2498607B1 (pt) 1983-07-29

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