DE3260408D1 - Process for the preparation of 17-alpha-hydroxy-17-beta-hydroxyacetyl steroids, and corresponding intermediates obtained - Google Patents

Process for the preparation of 17-alpha-hydroxy-17-beta-hydroxyacetyl steroids, and corresponding intermediates obtained

Info

Publication number
DE3260408D1
DE3260408D1 DE8282400026T DE3260408T DE3260408D1 DE 3260408 D1 DE3260408 D1 DE 3260408D1 DE 8282400026 T DE8282400026 T DE 8282400026T DE 3260408 T DE3260408 T DE 3260408T DE 3260408 D1 DE3260408 D1 DE 3260408D1
Authority
DE
Germany
Prior art keywords
carbon atoms
hydroxyacetyl
steroids
beta
alpha
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
DE8282400026T
Other languages
English (en)
Inventor
Lucien Nedelec
Vesperto Torelli
Michel Hardy
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Sanofi Aventis France
Original Assignee
Roussel Uclaf SA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Roussel Uclaf SA filed Critical Roussel Uclaf SA
Application granted granted Critical
Publication of DE3260408D1 publication Critical patent/DE3260408D1/de
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J41/00—Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring
    • C07J41/0033—Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring not covered by C07J41/0005
    • C07J41/005—Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring not covered by C07J41/0005 the 17-beta position being substituted by an uninterrupted chain of only two carbon atoms, e.g. pregnane derivatives
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J5/00—Normal steroids containing carbon, hydrogen, halogen or oxygen, substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane and substituted in position 21 by only one singly bound oxygen atom, i.e. only one oxygen bound to position 21 by a single bond
    • C07J5/0046—Normal steroids containing carbon, hydrogen, halogen or oxygen, substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane and substituted in position 21 by only one singly bound oxygen atom, i.e. only one oxygen bound to position 21 by a single bond substituted in position 17 alfa
    • C07J5/0053—Normal steroids containing carbon, hydrogen, halogen or oxygen, substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane and substituted in position 21 by only one singly bound oxygen atom, i.e. only one oxygen bound to position 21 by a single bond substituted in position 17 alfa not substituted in position 16
DE8282400026T 1981-01-29 1982-01-08 Process for the preparation of 17-alpha-hydroxy-17-beta-hydroxyacetyl steroids, and corresponding intermediates obtained Expired DE3260408D1 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR8101688A FR2498607A1 (fr) 1981-01-29 1981-01-29 Nouveau procede de preparation de 17a-hydroxy 17b-hydroxyacetyle steroides, produits intermediaires correspondants et produits finals obtenus

Publications (1)

Publication Number Publication Date
DE3260408D1 true DE3260408D1 (en) 1984-08-30

Family

ID=9254633

Family Applications (1)

Application Number Title Priority Date Filing Date
DE8282400026T Expired DE3260408D1 (en) 1981-01-29 1982-01-08 Process for the preparation of 17-alpha-hydroxy-17-beta-hydroxyacetyl steroids, and corresponding intermediates obtained

Country Status (10)

Country Link
US (1) US4565656A (de)
EP (1) EP0058097B1 (de)
JP (1) JPS57144299A (de)
AT (1) ATE8638T1 (de)
DE (1) DE3260408D1 (de)
DK (1) DK37782A (de)
FI (1) FI77462C (de)
FR (1) FR2498607A1 (de)
HU (1) HU187843B (de)
PT (1) PT74343B (de)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0123736A1 (de) * 1983-04-29 1984-11-07 Gist-Brocades N.V. Verfahren zur Herstellung von 21-Hydroxy-20-keto-delta-16-steroiden und in diesem Verfahren erhaltene Zwischenprodukte
US4910191A (en) * 1988-06-28 1990-03-20 Merrell Dow Pharmaceuticals Inc. 19-substituted progesterone derivatives useful as 19-hydroxylase inhibitors
US5202316A (en) * 1989-03-22 1993-04-13 Roussel Uclaf N,N,N',N'-6-(1-piperazinyl)-2,5-pyridinediamines
FR2683530B1 (fr) * 1991-11-08 1994-01-21 Roussel Uclaf Nouveau procede de preparation de derives 20-oxo 17 alpha, 21-dihydroxyles du pregnane et nouveaux intermediaires.
FR2719588B1 (fr) * 1994-05-03 1996-06-07 Roussel Uclaf Nouveau procédé de préparation de la substance "S" et nouveaux intermédiaires.

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3793350A (en) * 1971-10-01 1974-02-19 Syntex Corp Process for preparing 17alpha,21-dihydroxy-20-keto-pregnanes,derivatives and intermediates thereof
DE2603266A1 (de) * 1976-01-29 1977-08-11 Hoechst Ag 17-hydroxyacetylsteroide und verfahren zu ihrer herstellung
DE2655104A1 (de) * 1976-12-04 1978-06-08 Hoechst Ag Verfahren zur herstellung von 17alpha-hydroxy-21-acetoxy-progesteron
DE2704130A1 (de) * 1977-01-28 1978-08-10 Schering Ag Verfahren zur herstellung von 17 beta- hydroxy-20-alkoxy-pregnan-21-saeure-derivaten
FR2462445A1 (fr) * 1979-07-31 1981-02-13 Roussel Uclaf Nouveaux derives 17-/(hydroxymethyl) (formamido) methylene/steroides, leur procede de preparation et leur application a l'introduction de la chaine laterale hydroxyacetyle

Also Published As

Publication number Publication date
FR2498607A1 (fr) 1982-07-30
DK37782A (da) 1982-07-30
JPH036158B2 (de) 1991-01-29
EP0058097A2 (de) 1982-08-18
FI820240L (fi) 1982-07-30
ATE8638T1 (de) 1984-08-15
US4565656A (en) 1986-01-21
PT74343B (fr) 1984-05-30
EP0058097A3 (en) 1982-10-27
FI77462C (fi) 1989-03-10
FR2498607B1 (de) 1983-07-29
PT74343A (fr) 1982-02-01
EP0058097B1 (de) 1984-07-25
HU187843B (en) 1986-02-28
JPS57144299A (en) 1982-09-06
FI77462B (fi) 1988-11-30

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Legal Events

Date Code Title Description
8339 Ceased/non-payment of the annual fee