DK3775909T3 - Midler og fremgangsmåder til glykoprofilering af et protein - Google Patents

Midler og fremgangsmåder til glykoprofilering af et protein Download PDF

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Publication number
DK3775909T3
DK3775909T3 DK19718572.1T DK19718572T DK3775909T3 DK 3775909 T3 DK3775909 T3 DK 3775909T3 DK 19718572 T DK19718572 T DK 19718572T DK 3775909 T3 DK3775909 T3 DK 3775909T3
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DK
Denmark
Prior art keywords
glycoprofiling
protein
agents
methods
Prior art date
Application number
DK19718572.1T
Other languages
English (en)
Inventor
Tomas Bertok
Jan Tkac
Original Assignee
Glycanostics S R O
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Application filed by Glycanostics S R O filed Critical Glycanostics S R O
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Publication of DK3775909T3 publication Critical patent/DK3775909T3/da

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    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/574Immunoassay; Biospecific binding assay; Materials therefor for cancer
    • G01N33/57407Specifically defined cancers
    • G01N33/57434Specifically defined cancers of prostate
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/564Immunoassay; Biospecific binding assay; Materials therefor for pre-existing immune complex or autoimmune disease, i.e. systemic lupus erythematosus, rheumatoid arthritis, multiple sclerosis, rheumatoid factors or complement components C1-C9
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/574Immunoassay; Biospecific binding assay; Materials therefor for cancer
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/574Immunoassay; Biospecific binding assay; Materials therefor for cancer
    • G01N33/57484Immunoassay; Biospecific binding assay; Materials therefor for cancer involving compounds serving as markers for tumor, cancer, neoplasia, e.g. cellular determinants, receptors, heat shock/stress proteins, A-protein, oligosaccharides, metabolites
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/68Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
    • G01N33/6893Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids related to diseases not provided for elsewhere
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2333/00Assays involving biological materials from specific organisms or of a specific nature
    • G01N2333/415Assays involving biological materials from specific organisms or of a specific nature from plants
    • G01N2333/42Lectins, e.g. concanavalin, phytohaemagglutinin
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2333/00Assays involving biological materials from specific organisms or of a specific nature
    • G01N2333/435Assays involving biological materials from specific organisms or of a specific nature from animals; from humans
    • G01N2333/46Assays involving biological materials from specific organisms or of a specific nature from animals; from humans from vertebrates
    • G01N2333/47Assays involving proteins of known structure or function as defined in the subgroups
    • G01N2333/4701Details
    • G01N2333/4724Lectins
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2400/00Assays, e.g. immunoassays or enzyme assays, involving carbohydrates
    • G01N2400/02Assays, e.g. immunoassays or enzyme assays, involving carbohydrates involving antibodies to sugar part of glycoproteins
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2800/00Detection or diagnosis of diseases
    • G01N2800/24Immunology or allergic disorders
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2800/00Detection or diagnosis of diseases
    • G01N2800/50Determining the risk of developing a disease
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2800/00Detection or diagnosis of diseases
    • G01N2800/70Mechanisms involved in disease identification
    • G01N2800/7095Inflammation

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Immunology (AREA)
  • Engineering & Computer Science (AREA)
  • Hematology (AREA)
  • Urology & Nephrology (AREA)
  • Molecular Biology (AREA)
  • Biomedical Technology (AREA)
  • Chemical & Material Sciences (AREA)
  • Cell Biology (AREA)
  • Physics & Mathematics (AREA)
  • General Health & Medical Sciences (AREA)
  • Pathology (AREA)
  • General Physics & Mathematics (AREA)
  • Food Science & Technology (AREA)
  • Medicinal Chemistry (AREA)
  • Biotechnology (AREA)
  • Analytical Chemistry (AREA)
  • Biochemistry (AREA)
  • Microbiology (AREA)
  • Oncology (AREA)
  • Hospice & Palliative Care (AREA)
  • Rehabilitation Therapy (AREA)
  • Rheumatology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
DK19718572.1T 2018-03-26 2019-03-25 Midler og fremgangsmåder til glykoprofilering af et protein DK3775909T3 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP18163899 2018-03-26
PCT/EP2019/057386 WO2019185515A1 (en) 2018-03-26 2019-03-25 Means and methods for glycoprofiling of a protein

Publications (1)

Publication Number Publication Date
DK3775909T3 true DK3775909T3 (da) 2023-07-24

Family

ID=61800357

Family Applications (1)

Application Number Title Priority Date Filing Date
DK19718572.1T DK3775909T3 (da) 2018-03-26 2019-03-25 Midler og fremgangsmåder til glykoprofilering af et protein

Country Status (18)

Country Link
US (1) US20210048437A1 (da)
EP (2) EP3775909B1 (da)
JP (1) JP2021519443A (da)
KR (1) KR20200138300A (da)
AU (1) AU2019246007A1 (da)
CA (1) CA3091733A1 (da)
DK (1) DK3775909T3 (da)
ES (1) ES2950740T3 (da)
FI (1) FI3775909T3 (da)
HR (1) HRP20230744T1 (da)
HU (1) HUE062414T2 (da)
IL (1) IL277194A (da)
LT (1) LT3775909T (da)
PL (1) PL3775909T3 (da)
PT (1) PT3775909T (da)
RS (1) RS64431B1 (da)
SI (1) SI3775909T1 (da)
WO (1) WO2019185515A1 (da)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN111208304B (zh) * 2020-01-20 2023-06-16 中国医学科学院北京协和医院 肿瘤来源IgG在甲状旁腺癌诊断和预后中的用途
CN113009130B (zh) * 2021-02-10 2022-08-23 中国医学科学院北京协和医院 一种用于诊断原发性干燥综合征的生物标志物及其用途
CN113009131B (zh) * 2021-02-10 2022-08-23 中国医学科学院北京协和医院 一种用于诊断原发性干燥综合征的生物标志物及其用途
WO2022186317A1 (ja) * 2021-03-03 2022-09-09 株式会社先端生命科学研究所 がん検出方法、がん検査方法、及びこれらに用いるキット
MX2024001598A (es) 2021-08-06 2024-02-15 Glycanostics S R O Estandar para el glicoperfilado de proteinas.
CN113702637B (zh) * 2021-08-09 2023-04-07 西北大学 乳腺癌新辅助化疗疗效预测的凝集素测试载体和试剂盒以及预测模型
CN113721029B (zh) * 2021-08-25 2023-06-06 西北大学 特定凝集素组合鉴别肝硬化、肝癌的测试工具及系统
WO2023025927A1 (en) 2021-08-26 2023-03-02 Glycanostics S.R.O Glycoprotein biomarkers for diagnosing cancer
CA3231890A1 (en) 2021-09-14 2023-03-23 Jan Tkac Use of lectins to determine mammaglobin-a glycoforms in breast cancer
WO2023198337A1 (en) 2022-04-12 2023-10-19 Glycanostics S.R.O. Means and methods for high-throughput glycoprofiling of proteins
WO2024059750A2 (en) * 2022-09-16 2024-03-21 Venn Biosciences Corporation Diagnosis of ovarian cancer using targeted quantification of site-specific protein glycosylation

Family Cites Families (38)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4676A (en) 1846-07-31 roller
US4816A (en) 1846-10-17 Bell machinery for hotels
US567A (en) 1838-01-09 Machine for r-uibbii
US980A (en) 1838-10-13 Improvement in the mode of hardening or chilling the hubs of car and other wheels
GB8308235D0 (en) 1983-03-25 1983-05-05 Celltech Ltd Polypeptides
US4816567A (en) 1983-04-08 1989-03-28 Genentech, Inc. Recombinant immunoglobin preparations
JPS6147500A (ja) 1984-08-15 1986-03-07 Res Dev Corp Of Japan キメラモノクロ−ナル抗体及びその製造法
EP0173494A3 (en) 1984-08-27 1987-11-25 The Board Of Trustees Of The Leland Stanford Junior University Chimeric receptors by dna splicing and expression
GB8422238D0 (en) 1984-09-03 1984-10-10 Neuberger M S Chimeric proteins
US4676980A (en) 1985-09-23 1987-06-30 The United States Of America As Represented By The Secretary Of The Department Of Health And Human Services Target specific cross-linked heteroantibodies
US5225539A (en) 1986-03-27 1993-07-06 Medical Research Council Recombinant altered antibodies and methods of making altered antibodies
GB8607679D0 (en) 1986-03-27 1986-04-30 Winter G P Recombinant dna product
DE3883899T3 (de) 1987-03-18 1999-04-22 Sb2, Inc., Danville, Calif. Geänderte antikörper.
EP0768377A1 (en) 1988-09-02 1997-04-16 Protein Engineering Corporation Generation and selection of recombinant varied binding proteins
US5223409A (en) 1988-09-02 1993-06-29 Protein Engineering Corp. Directed evolution of novel binding proteins
US5530101A (en) 1988-12-28 1996-06-25 Protein Design Labs, Inc. Humanized immunoglobulins
US5859205A (en) 1989-12-21 1999-01-12 Celltech Limited Humanised antibodies
US5427908A (en) 1990-05-01 1995-06-27 Affymax Technologies N.V. Recombinant library screening methods
GB9015198D0 (en) 1990-07-10 1990-08-29 Brien Caroline J O Binding substance
AU665190B2 (en) 1990-07-10 1995-12-21 Cambridge Antibody Technology Limited Methods for producing members of specific binding pairs
GB9021679D0 (en) 1990-10-05 1990-11-21 Gorman Scott David Antibody preparation
ES2113940T3 (es) 1990-12-03 1998-05-16 Genentech Inc Metodo de enriquecimiento para variantes de proteinas con propiedades de union alteradas.
AU1545692A (en) 1991-03-01 1992-10-06 Protein Engineering Corporation Process for the development of binding mini-proteins
CA2108147C (en) 1991-04-10 2009-01-06 Angray Kang Heterodimeric receptor libraries using phagemids
DK0590058T3 (da) 1991-06-14 2004-03-29 Genentech Inc Humaniseret heregulin-antistof
DE4122599C2 (de) 1991-07-08 1993-11-11 Deutsches Krebsforsch Phagemid zum Screenen von Antikörpern
EP1978033A3 (en) 1995-04-27 2008-12-24 Amgen Fremont Inc. Human antibodies derived from immunized xenomice
AU2466895A (en) 1995-04-28 1996-11-18 Abgenix, Inc. Human antibodies derived from immunized xenomice
EP0859841B1 (en) 1995-08-18 2002-06-19 MorphoSys AG Protein/(poly)peptide libraries
EP1500329B1 (en) 1996-12-03 2012-03-21 Amgen Fremont Inc. Human antibodies that specifically bind human TNF alpha
AU736549B2 (en) 1997-05-21 2001-08-02 Merck Patent Gesellschaft Mit Beschrankter Haftung Method for the production of non-immunogenic proteins
CA2342967A1 (en) 1998-12-08 2000-06-15 Biovation Limited Modifying protein immunogenicity
US7838634B2 (en) * 2005-04-15 2010-11-23 Van Andel Research Institute Methods for measuring glycan levels of proteins
JP4711190B2 (ja) * 2006-07-28 2011-06-29 国立大学法人 東京大学 グリコシル化異常症の検査方法
WO2009075883A2 (en) * 2007-12-12 2009-06-18 University Of Georgia Research Foundation, Inc. Glycoprotein cancer biomarker
US9169327B2 (en) 2008-03-12 2015-10-27 Rowan University Targeting of podoplanin with lectin for use in the prevention and treatment of cancer
US20110129849A1 (en) * 2008-07-25 2011-06-02 The Johns Hopkins University Detection of prostate cancer using psa glycosylation patterns
JP2010091308A (ja) * 2008-10-04 2010-04-22 Sapporo Medical Univ レクチン吸収法による前立腺がんの診断方法及び判定キット

Also Published As

Publication number Publication date
IL277194A (en) 2020-10-29
WO2019185515A1 (en) 2019-10-03
PL3775909T3 (pl) 2023-09-18
RS64431B1 (sr) 2023-09-29
EP3775909A1 (en) 2021-02-17
EP4253958A2 (en) 2023-10-04
PT3775909T (pt) 2023-07-19
EP3775909B1 (en) 2023-05-10
KR20200138300A (ko) 2020-12-09
FI3775909T3 (fi) 2023-08-01
US20210048437A1 (en) 2021-02-18
HRP20230744T1 (hr) 2023-10-27
ES2950740T3 (es) 2023-10-13
JP2021519443A (ja) 2021-08-10
AU2019246007A1 (en) 2020-09-10
SI3775909T1 (sl) 2023-10-30
EP4253958A3 (en) 2023-12-06
CA3091733A1 (en) 2019-10-03
LT3775909T (lt) 2023-08-10
HUE062414T2 (hu) 2023-10-28

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