DK3762004T3 - Behandling af tumorer ved hjælp af en kombination af en oncolytisk adenovirus og en CDK4/6 inhibitor - Google Patents
Behandling af tumorer ved hjælp af en kombination af en oncolytisk adenovirus og en CDK4/6 inhibitor Download PDFInfo
- Publication number
- DK3762004T3 DK3762004T3 DK19710999.4T DK19710999T DK3762004T3 DK 3762004 T3 DK3762004 T3 DK 3762004T3 DK 19710999 T DK19710999 T DK 19710999T DK 3762004 T3 DK3762004 T3 DK 3762004T3
- Authority
- DK
- Denmark
- Prior art keywords
- cdk4
- tumors
- inhibitor
- treatment
- combination
- Prior art date
Links
- 229940124297 CDK 4/6 inhibitor Drugs 0.000 title 1
- 206010028980 Neoplasm Diseases 0.000 title 1
- 230000000174 oncolytic effect Effects 0.000 title 1
- 241000701161 unidentified adenovirus Species 0.000 title 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
- A61K35/66—Microorganisms or materials therefrom
- A61K35/76—Viruses; Subviral particles; Bacteriophages
- A61K35/761—Adenovirus
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
- A61K31/506—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim not condensed and containing further heterocyclic rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
- A61K31/519—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with heterocyclic rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2300/00—Mixtures or combinations of active ingredients, wherein at least one active ingredient is fully defined in groups A61K31/00 - A61K41/00
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2710/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA dsDNA viruses
- C12N2710/00011—Details
- C12N2710/10011—Adenoviridae
- C12N2710/10311—Mastadenovirus, e.g. human or simian adenoviruses
- C12N2710/10332—Use of virus as therapeutic agent, other than vaccine, e.g. as cytolytic agent
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Epidemiology (AREA)
- Virology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- General Chemical & Material Sciences (AREA)
- Microbiology (AREA)
- Mycology (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP18000210 | 2018-03-05 | ||
| PCT/EP2019/000067 WO2019170283A1 (en) | 2018-03-05 | 2019-03-05 | Treatment of tumors by a combination of an oncolytic adenovirus and a cdk4/6 inhibitor |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| DK3762004T3 true DK3762004T3 (da) | 2023-11-27 |
Family
ID=61569019
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DK19710999.4T DK3762004T3 (da) | 2018-03-05 | 2019-03-05 | Behandling af tumorer ved hjælp af en kombination af en oncolytisk adenovirus og en CDK4/6 inhibitor |
Country Status (13)
| Country | Link |
|---|---|
| US (1) | US20210038661A1 (da) |
| EP (1) | EP3762004B1 (da) |
| JP (1) | JP2021517119A (da) |
| KR (1) | KR20210031852A (da) |
| CN (1) | CN112533620A (da) |
| AU (1) | AU2019232768A1 (da) |
| CA (1) | CA3092907A1 (da) |
| DK (1) | DK3762004T3 (da) |
| ES (1) | ES2965632T3 (da) |
| FI (1) | FI3762004T3 (da) |
| HU (1) | HUE064471T2 (da) |
| SG (1) | SG11202007873VA (da) |
| WO (1) | WO2019170283A1 (da) |
Families Citing this family (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP4025229A1 (en) * | 2019-09-05 | 2022-07-13 | Klinikum rechts der Isar der Technischen Universität München | Treatment of tumors by a combination of an oncolytic adenovirus, a cdk4/6 inhibitor and a further therapeutically active agent |
| KR102341347B1 (ko) * | 2019-11-28 | 2021-12-20 | 의료법인 성광의료재단 | 암 치료제에 대한 내성 암의 진단을 위한 조성물, 키트 및 방법 |
| WO2024043322A1 (ja) * | 2022-08-25 | 2024-02-29 | 富士フイルム株式会社 | 目的ウイルスの製造方法、および培養組成物 |
Family Cites Families (14)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP1493825A3 (en) | 1990-06-11 | 2005-02-09 | Gilead Sciences, Inc. | Method for producing nucleic acid ligands |
| DE59708838D1 (de) | 1996-08-30 | 2003-01-09 | Jens Peter Fuerste | Spiegelselektion und spiegelevolution von nucleinsäuren |
| DE19742706B4 (de) | 1997-09-26 | 2013-07-25 | Pieris Proteolab Ag | Lipocalinmuteine |
| CN1655827B (zh) * | 2002-05-27 | 2010-06-23 | 佩尔·松内·霍尔姆 | 腺病毒和编码其的核酸的新应用 |
| MXPA05004074A (es) * | 2002-10-15 | 2005-09-20 | Sonne Holm Per | Nuevos adenovirus, acidos nucleicos que los codifican y su uso. |
| RU2393221C2 (ru) * | 2002-10-15 | 2010-06-27 | Пер Сонне ХОЛЬМ | Аденовирус с обращенной генной экспрессией и его применение |
| WO2005052143A2 (de) * | 2003-11-14 | 2005-06-09 | Per Sonne Holm | Neue adenoviren, dafür codierende nukleinsäuren und deren verwendung |
| EA030465B1 (ru) * | 2011-07-01 | 2018-08-31 | Новартис Аг | Комбинированная терапия, включающая ингибитор cdk4/6 и ингибитор pi3k для применения в лечении рака |
| AU2014236207B2 (en) * | 2013-03-14 | 2019-05-23 | Salk Institute For Biological Studies | Oncolytic adenovirus compositions |
| US9624247B2 (en) * | 2013-05-28 | 2017-04-18 | Novartis Ag | Pyrazolo-pyrrolidin-4-one derivatives as bet inhibitors and their use in the treatment of disease |
| WO2015018521A1 (en) * | 2013-08-06 | 2015-02-12 | Oncoethix Sa | Method of treating diffuse large b-cell lymphoma (dlbcl) using a bet-bromodomain inhibitor |
| CN105916848B (zh) * | 2013-12-31 | 2018-01-09 | 山东轩竹医药科技有限公司 | 激酶抑制剂及其用途 |
| CA2948643C (en) * | 2014-05-30 | 2022-09-06 | British Columbia Cancer Agency Branch | Androgen receptor modulators and methods for their use |
| CA2985029A1 (en) * | 2015-05-04 | 2016-11-10 | Vcn Biosciences Sl | Oncolytic adenoviruses with mutations in immunodominant adenovirus epitopes and their use in cancer treatment |
-
2019
- 2019-03-05 CA CA3092907A patent/CA3092907A1/en active Pending
- 2019-03-05 KR KR1020207025771A patent/KR20210031852A/ko active Search and Examination
- 2019-03-05 DK DK19710999.4T patent/DK3762004T3/da active
- 2019-03-05 FI FIEP19710999.4T patent/FI3762004T3/fi active
- 2019-03-05 JP JP2020546331A patent/JP2021517119A/ja active Pending
- 2019-03-05 EP EP19710999.4A patent/EP3762004B1/en active Active
- 2019-03-05 WO PCT/EP2019/000067 patent/WO2019170283A1/en unknown
- 2019-03-05 HU HUE19710999A patent/HUE064471T2/hu unknown
- 2019-03-05 ES ES19710999T patent/ES2965632T3/es active Active
- 2019-03-05 CN CN201980016785.2A patent/CN112533620A/zh active Pending
- 2019-03-05 SG SG11202007873VA patent/SG11202007873VA/en unknown
- 2019-03-05 US US16/978,048 patent/US20210038661A1/en active Pending
- 2019-03-05 AU AU2019232768A patent/AU2019232768A1/en active Pending
Also Published As
| Publication number | Publication date |
|---|---|
| CA3092907A1 (en) | 2019-09-12 |
| EP3762004A1 (en) | 2021-01-13 |
| US20210038661A1 (en) | 2021-02-11 |
| JP2021517119A (ja) | 2021-07-15 |
| AU2019232768A1 (en) | 2020-09-03 |
| KR20210031852A (ko) | 2021-03-23 |
| WO2019170283A8 (en) | 2019-11-07 |
| WO2019170283A1 (en) | 2019-09-12 |
| SG11202007873VA (en) | 2020-09-29 |
| RU2020132466A3 (da) | 2022-04-05 |
| FI3762004T3 (fi) | 2023-12-11 |
| HUE064471T2 (hu) | 2024-03-28 |
| ES2965632T3 (es) | 2024-04-16 |
| CN112533620A (zh) | 2021-03-19 |
| RU2020132466A (ru) | 2022-04-05 |
| EP3762004B1 (en) | 2023-09-13 |
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