DK3723791T3 - Rekombinante igg-fc-multimere til behandling af neuromyelitis optica - Google Patents

Rekombinante igg-fc-multimere til behandling af neuromyelitis optica Download PDF

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Publication number
DK3723791T3
DK3723791T3 DK18829780.8T DK18829780T DK3723791T3 DK 3723791 T3 DK3723791 T3 DK 3723791T3 DK 18829780 T DK18829780 T DK 18829780T DK 3723791 T3 DK3723791 T3 DK 3723791T3
Authority
DK
Denmark
Prior art keywords
multimers
treatment
neuromyelitis optica
recombinant igg
igg
Prior art date
Application number
DK18829780.8T
Other languages
English (en)
Inventor
Rolf Spirig
Morelli Adriana Baz
Alan Verkman
Lukmanee Tradtrantip
Original Assignee
CSL Behring Lengnau AG
Univ California
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by CSL Behring Lengnau AG, Univ California filed Critical CSL Behring Lengnau AG
Application granted granted Critical
Publication of DK3723791T3 publication Critical patent/DK3723791T3/da

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    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K16/00Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • A61P37/02Immunomodulators
    • A61P37/06Immunosuppressants, e.g. drugs for graft rejection
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00Drugs for disorders of the senses
    • A61P27/02Ophthalmic agents
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K16/00Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/505Medicinal preparations containing antigens or antibodies comprising antibodies
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/30Immunoglobulins specific features characterized by aspects of specificity or valency
    • C07K2317/35Valency
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/50Immunoglobulins specific features characterized by immunoglobulin fragments
    • C07K2317/52Constant or Fc region; Isotype
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/50Immunoglobulins specific features characterized by immunoglobulin fragments
    • C07K2317/52Constant or Fc region; Isotype
    • C07K2317/53Hinge
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/60Immunoglobulins specific features characterized by non-natural combinations of immunoglobulin fragments
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2319/00Fusion polypeptide
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2319/00Fusion polypeptide
    • C07K2319/70Fusion polypeptide containing domain for protein-protein interaction
DK18829780.8T 2017-12-14 2018-12-14 Rekombinante igg-fc-multimere til behandling af neuromyelitis optica DK3723791T3 (da)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201762598592P 2017-12-14 2017-12-14
EP18168448 2018-04-20
PCT/EP2018/084894 WO2019115745A1 (en) 2017-12-14 2018-12-14 RECOMBINANT igG Fc MULTIMERS FOR THE TREATMENT OF NEUROMYELITIS OPTICA

Publications (1)

Publication Number Publication Date
DK3723791T3 true DK3723791T3 (da) 2024-04-08

Family

ID=64949238

Family Applications (1)

Application Number Title Priority Date Filing Date
DK18829780.8T DK3723791T3 (da) 2017-12-14 2018-12-14 Rekombinante igg-fc-multimere til behandling af neuromyelitis optica

Country Status (8)

Country Link
US (1) US20210095006A1 (da)
EP (1) EP3723791B1 (da)
JP (1) JP7351835B2 (da)
CN (1) CN112004550A (da)
AU (1) AU2018382586A1 (da)
CA (1) CA3085385A1 (da)
DK (1) DK3723791T3 (da)
WO (1) WO2019115745A1 (da)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US10373019B2 (en) * 2016-01-13 2019-08-06 Ford Global Technologies, Llc Low- and high-fidelity classifiers applied to road-scene images
CN114401985A (zh) * 2019-09-13 2022-04-26 康诺贝林伦瑙有限公司 用于治疗免疫复合物介导的肾病症的重组IgG Fc多聚体
CN114894911B (zh) * 2022-03-18 2023-10-24 辽宁成大生物股份有限公司 一种控制牛血清产品质量方法

Family Cites Families (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5677425A (en) 1987-09-04 1997-10-14 Celltech Therapeutics Limited Recombinant antibody
GB9625640D0 (en) 1996-12-10 1997-01-29 Celltech Therapeutics Ltd Biological products
GB9720054D0 (en) 1997-09-19 1997-11-19 Celltech Therapeutics Ltd Biological products
GB0315450D0 (en) 2003-07-01 2003-08-06 Celltech R&D Ltd Biological products
PL1644412T5 (pl) 2003-07-01 2019-01-31 Ucb Biopharma Sprl Modyfikowane fragmenty Fab przeciwciała
GB0315457D0 (en) 2003-07-01 2003-08-06 Celltech R&D Ltd Biological products
US8680237B2 (en) 2007-06-01 2014-03-25 Gliknik Inc. Immunoglobulin constant region FC receptor binding agents
MX347343B (es) 2010-07-28 2017-04-21 Gliknik Inc Proteinas de fusion de fragmentos de proteinas humanas naturales para crear composiciones de fc de inmunoglobulinas multimerizadas ordenadamente.
AU2012392760C1 (en) 2012-10-17 2021-08-12 CSL Behring Lengnau AG Immunomodulatory proteins
EP3114137A1 (en) * 2014-03-05 2017-01-11 UCB Biopharma SPRL Multimeric fc proteins
JP6851200B2 (ja) * 2014-03-05 2021-03-31 ユーシービー バイオファルマ エスアールエル 多量体Fcタンパク質
US20180044416A1 (en) * 2015-03-05 2018-02-15 Ucb Biopharma Sprl Polymeric Fc proteins and methods of screening to alter their functional characteristics
GB201511787D0 (en) * 2015-07-06 2015-08-19 Ucb Biopharma Sprl Proteins
KR102649702B1 (ko) 2015-07-24 2024-03-21 글리크닉 인코포레이티드 향상된 상보체 결합을 갖는 규칙적으로 다형체화된 면역글로불린 fc 조성물을 생성하기 위한 인간 단백질 단편의 융합 단백질
BR112018014668A2 (pt) 2016-01-27 2018-12-11 Csl Behring Recombinant Facility Ag multímeros de fc de igg recombinante
BR112018070022A2 (pt) 2016-03-30 2019-02-05 Ab biosciences inc composições de imunoglobulina intravenosa recombinante (rivig) e métodos para sua produção e uso

Also Published As

Publication number Publication date
CN112004550A (zh) 2020-11-27
WO2019115745A1 (en) 2019-06-20
JP2021506772A (ja) 2021-02-22
US20210095006A1 (en) 2021-04-01
JP7351835B2 (ja) 2023-09-27
EP3723791A1 (en) 2020-10-21
AU2018382586A1 (en) 2020-07-02
EP3723791B1 (en) 2024-02-21
CA3085385A1 (en) 2019-06-20

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