DK3719013T3 - Pyrimidinsulfamidderivat og fremgangsmdåde til fremstilling og medicinsk anvendelse heraf - Google Patents

Pyrimidinsulfamidderivat og fremgangsmdåde til fremstilling og medicinsk anvendelse heraf Download PDF

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Publication number
DK3719013T3
DK3719013T3 DK18881280.4T DK18881280T DK3719013T3 DK 3719013 T3 DK3719013 T3 DK 3719013T3 DK 18881280 T DK18881280 T DK 18881280T DK 3719013 T3 DK3719013 T3 DK 3719013T3
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DK
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Prior art keywords
production
medical use
sulfamide derivative
pyrimidine
pyrimidine sulfamide
Prior art date
Application number
DK18881280.4T
Other languages
English (en)
Inventor
Yunfu Luo
Maoyi Lei
Junmiao Li
Yu Xu
Ran Wei
Shuhui Chen
Original Assignee
Wuxi Biocity Biopharmaceutics Co Ltd
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Application filed by Wuxi Biocity Biopharmaceutics Co Ltd filed Critical Wuxi Biocity Biopharmaceutics Co Ltd
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Publication of DK3719013T3 publication Critical patent/DK3719013T3/da

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    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D407/00Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen atoms as the only ring hetero atoms, not provided for by group C07D405/00
    • C07D407/14Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen atoms as the only ring hetero atoms, not provided for by group C07D405/00 containing three or more hetero rings
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D405/00Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/14Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing three or more hetero rings
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A61K31/506Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim not condensed and containing further heterocyclic rings
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/12Antihypertensives
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D417/00Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/14Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing three or more hetero rings
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D471/00Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04Ortho-condensed systems
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D491/00Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
    • C07D491/02Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains two hetero rings
    • C07D491/10Spiro-condensed systems
    • C07D491/107Spiro-condensed systems with only one oxygen atom as ring hetero atom in the oxygen-containing ring

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Cardiology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Plural Heterocyclic Compounds (AREA)
DK18881280.4T 2017-11-21 2018-11-19 Pyrimidinsulfamidderivat og fremgangsmdåde til fremstilling og medicinsk anvendelse heraf DK3719013T3 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
CN201711168111 2017-11-21
PCT/CN2018/116196 WO2019101039A1 (zh) 2017-11-21 2018-11-19 嘧啶磺酰胺类衍生物、其制备方法及其在医药上的应用

Publications (1)

Publication Number Publication Date
DK3719013T3 true DK3719013T3 (da) 2023-04-03

Family

ID=66630436

Family Applications (1)

Application Number Title Priority Date Filing Date
DK18881280.4T DK3719013T3 (da) 2017-11-21 2018-11-19 Pyrimidinsulfamidderivat og fremgangsmdåde til fremstilling og medicinsk anvendelse heraf

Country Status (19)

Country Link
US (1) US11319305B2 (da)
EP (1) EP3719013B1 (da)
JP (1) JP7245832B2 (da)
CN (1) CN111479808B (da)
AU (1) AU2018372752B2 (da)
BR (1) BR112020010149A8 (da)
CA (1) CA3083019A1 (da)
DK (1) DK3719013T3 (da)
ES (1) ES2936864T3 (da)
FI (1) FI3719013T3 (da)
HR (1) HRP20230318T1 (da)
HU (1) HUE061515T2 (da)
IL (1) IL274773B2 (da)
LT (1) LT3719013T (da)
PL (1) PL3719013T3 (da)
PT (1) PT3719013T (da)
RS (1) RS64040B1 (da)
SI (1) SI3719013T1 (da)
WO (1) WO2019101039A1 (da)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN109232546B (zh) * 2018-09-25 2020-09-04 中国人民解放军总医院 一种嘧啶磺酰胺类衍生物的医药用途
US20220220098A1 (en) * 2019-05-22 2022-07-14 Wuxi Biocity Biopharmaceutics Co., Ltd. Crystal form of pyrimidine sulfonamide compound and preparation method therefor

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2315614C (en) * 1999-07-29 2004-11-02 Pfizer Inc. Pyrazoles
CA2348847A1 (en) * 2000-05-31 2001-11-30 Pfizer Inc. New isoxazole-sulfonamide endothelin antagonists
JP3490959B2 (ja) 2000-07-11 2004-01-26 三洋電機株式会社 受光素子及び受光モジュール
CN100432070C (zh) * 2000-12-18 2008-11-12 埃科特莱茵药品有限公司 新颖的磺酰胺类化合物及其作为内皮素受体拮抗剂的应用
AU2003285321B2 (en) 2002-12-02 2010-04-08 Actelion Pharmaceuticals Ltd Pyrimidine-sulfamides and their use as endothelian receptor antagonist
TW200628467A (en) * 2004-11-11 2006-08-16 Actelion Pharmaceuticals Ltd Novel sulfamides

Also Published As

Publication number Publication date
JP2021504330A (ja) 2021-02-15
CN111479808A (zh) 2020-07-31
EP3719013A1 (en) 2020-10-07
AU2018372752B2 (en) 2023-02-02
CA3083019A1 (en) 2019-05-31
BR112020010149A8 (pt) 2023-01-17
IL274773B2 (en) 2023-08-01
EP3719013B1 (en) 2023-01-04
US11319305B2 (en) 2022-05-03
RU2020119900A (ru) 2021-12-23
HUE061515T2 (hu) 2023-07-28
LT3719013T (lt) 2023-05-10
IL274773B1 (en) 2023-04-01
EP3719013A4 (en) 2021-04-21
SI3719013T1 (sl) 2023-05-31
HRP20230318T1 (hr) 2023-05-12
WO2019101039A1 (zh) 2019-05-31
RU2020119900A3 (da) 2021-12-23
AU2018372752A1 (en) 2020-07-02
ES2936864T3 (es) 2023-03-22
IL274773A (en) 2020-07-30
PT3719013T (pt) 2023-02-01
RS64040B1 (sr) 2023-04-28
PL3719013T3 (pl) 2023-05-08
BR112020010149A2 (pt) 2020-11-10
JP7245832B2 (ja) 2023-03-24
CN111479808B (zh) 2023-02-24
FI3719013T3 (fi) 2023-04-03
US20200283425A1 (en) 2020-09-10

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