DK3716951T3 - Fremgangsmåde og indretning til fremstilling af en fast dispersion - Google Patents
Fremgangsmåde og indretning til fremstilling af en fast dispersion Download PDFInfo
- Publication number
- DK3716951T3 DK3716951T3 DK18811797.2T DK18811797T DK3716951T3 DK 3716951 T3 DK3716951 T3 DK 3716951T3 DK 18811797 T DK18811797 T DK 18811797T DK 3716951 T3 DK3716951 T3 DK 3716951T3
- Authority
- DK
- Denmark
- Prior art keywords
- decoration
- preparing
- fixed dispersion
- dispersion
- fixed
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
- A61K9/1682—Processes
- A61K9/1694—Processes resulting in granules or microspheres of the matrix type containing more than 5% of excipient
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2004—Excipients; Inactive ingredients
- A61K9/2022—Organic macromolecular compounds
- A61K9/2031—Organic macromolecular compounds obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyethylene glycol, polyethylene oxide, poloxamers
- A61K9/204—Polyesters, e.g. poly(lactide-co-glycolide)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A61K31/4422—1,4-Dihydropyridines, e.g. nifedipine, nicardipine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
- A61K9/1605—Excipients; Inactive ingredients
- A61K9/1629—Organic macromolecular compounds
- A61K9/1641—Organic macromolecular compounds obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyethylene glycol, poloxamers
- A61K9/1647—Polyesters, e.g. poly(lactide-co-glycolide)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
- A61K9/1682—Processes
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B29—WORKING OF PLASTICS; WORKING OF SUBSTANCES IN A PLASTIC STATE IN GENERAL
- B29C—SHAPING OR JOINING OF PLASTICS; SHAPING OF MATERIAL IN A PLASTIC STATE, NOT OTHERWISE PROVIDED FOR; AFTER-TREATMENT OF THE SHAPED PRODUCTS, e.g. REPAIRING
- B29C48/00—Extrusion moulding, i.e. expressing the moulding material through a die or nozzle which imparts the desired form; Apparatus therefor
- B29C48/022—Extrusion moulding, i.e. expressing the moulding material through a die or nozzle which imparts the desired form; Apparatus therefor characterised by the choice of material
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B29—WORKING OF PLASTICS; WORKING OF SUBSTANCES IN A PLASTIC STATE IN GENERAL
- B29K—INDEXING SCHEME ASSOCIATED WITH SUBCLASSES B29B, B29C OR B29D, RELATING TO MOULDING MATERIALS OR TO MATERIALS FOR MOULDS, REINFORCEMENTS, FILLERS OR PREFORMED PARTS, e.g. INSERTS
- B29K2067/00—Use of polyesters or derivatives thereof, as moulding material
- B29K2067/04—Polyesters derived from hydroxycarboxylic acids
- B29K2067/043—PGA, i.e. polyglycolic acid or polyglycolide
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B29—WORKING OF PLASTICS; WORKING OF SUBSTANCES IN A PLASTIC STATE IN GENERAL
- B29K—INDEXING SCHEME ASSOCIATED WITH SUBCLASSES B29B, B29C OR B29D, RELATING TO MOULDING MATERIALS OR TO MATERIALS FOR MOULDS, REINFORCEMENTS, FILLERS OR PREFORMED PARTS, e.g. INSERTS
- B29K2067/00—Use of polyesters or derivatives thereof, as moulding material
- B29K2067/04—Polyesters derived from hydroxycarboxylic acids
- B29K2067/046—PLA, i.e. polylactic acid or polylactide
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B29—WORKING OF PLASTICS; WORKING OF SUBSTANCES IN A PLASTIC STATE IN GENERAL
- B29K—INDEXING SCHEME ASSOCIATED WITH SUBCLASSES B29B, B29C OR B29D, RELATING TO MOULDING MATERIALS OR TO MATERIALS FOR MOULDS, REINFORCEMENTS, FILLERS OR PREFORMED PARTS, e.g. INSERTS
- B29K2105/00—Condition, form or state of moulded material or of the material to be shaped
- B29K2105/0005—Condition, form or state of moulded material or of the material to be shaped containing compounding ingredients
- B29K2105/0035—Medical or pharmaceutical agents
Landscapes
- Health & Medical Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Animal Behavior & Ethology (AREA)
- Epidemiology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Medicinal Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicinal Preparation (AREA)
- Processes Of Treating Macromolecular Substances (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
EP17204645.0A EP3492070A1 (en) | 2017-11-30 | 2017-11-30 | Process and device for preparing a solid dispersion |
PCT/EP2018/083009 WO2019106090A1 (en) | 2017-11-30 | 2018-11-29 | Process and device for preparing a solid dispersion |
Publications (1)
Publication Number | Publication Date |
---|---|
DK3716951T3 true DK3716951T3 (da) | 2022-04-04 |
Family
ID=60811754
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DK18811797.2T DK3716951T3 (da) | 2017-11-30 | 2018-11-29 | Fremgangsmåde og indretning til fremstilling af en fast dispersion |
Country Status (17)
Country | Link |
---|---|
US (1) | US11413247B2 (da) |
EP (2) | EP3492070A1 (da) |
JP (1) | JP7250029B2 (da) |
CN (1) | CN111405894A (da) |
AU (1) | AU2018376566B2 (da) |
BR (1) | BR112020008646A2 (da) |
CL (1) | CL2020001176A1 (da) |
DK (1) | DK3716951T3 (da) |
ES (1) | ES2910012T3 (da) |
HU (1) | HUE058088T2 (da) |
IL (1) | IL274348A (da) |
MX (1) | MX2020004589A (da) |
PL (1) | PL3716951T3 (da) |
PT (1) | PT3716951T (da) |
SG (1) | SG11202004062WA (da) |
SI (1) | SI3716951T1 (da) |
WO (1) | WO2019106090A1 (da) |
Family Cites Families (18)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE3024416C2 (de) * | 1980-06-28 | 1982-04-15 | Gödecke AG, 1000 Berlin | Verfahren zur Herstellung von Arzneimitteln mit retardierter Wirkstoff-Freisetzung |
AU4316393A (en) * | 1992-05-22 | 1993-12-30 | Godecke Aktiengesellschaft | Process for preparing delayed-action medicinal compositions |
DE19721467A1 (de) * | 1997-05-22 | 1998-11-26 | Basf Ag | Verfahren zur Herstellung kleinteiliger Zubereitungen biologisch aktiver Stoffe |
WO1999021534A1 (en) | 1997-10-27 | 1999-05-06 | Merck Patent Gmbh | Solid state solutions and dispersions of poorly water soluble drugs |
JPH11286439A (ja) * | 1998-04-01 | 1999-10-19 | Senju Pharmaceut Co Ltd | 生分解性ポリマー型薬物放出システム |
US6455526B1 (en) * | 1998-12-16 | 2002-09-24 | Aventis Pharmaceuticals, Inc. | Biodegradable polymer encapsulated pharmaceutical compositions and method for preparing the same |
DE50210646D1 (de) | 2001-05-23 | 2007-09-20 | Hexal Ag | Verfahren zur herstellung von implantaten mittels lösungsmittelfreier herstellung eines homogenisats |
CN100594023C (zh) | 2003-02-03 | 2010-03-17 | 诺瓦提斯公司 | 药物制剂 |
CA2618255C (en) | 2005-08-08 | 2015-05-26 | Abbott Gmbh & Co. Kg | Itraconazole compositions with improved bioavailability |
EP2140883B1 (en) | 2007-04-20 | 2012-10-31 | Daido Chemical Corporation | Novel base for dry solid dispersion, solid dispersion containing the base, and composition containing the dispersion |
EP2187968A4 (en) | 2007-08-21 | 2013-02-20 | Univ Texas | THERMOKINETIC MIXING FOR PHARMACEUTICAL APPLICATIONS |
CN101254180B (zh) * | 2008-03-28 | 2010-11-10 | 辽宁正鑫药物研究有限公司 | 一种内容物为半固体组合物的尼莫地平胶囊剂及制备方法 |
EP2140861A1 (en) | 2008-06-30 | 2010-01-06 | Abbott GmbH & Co. KG | Pharmaceutical dosage form comprising polymeric carrier composition |
EP2308478A1 (en) * | 2009-10-06 | 2011-04-13 | Abbott GmbH & Co. KG | Delivery system for sustained release of a calcium-channel blocking agent |
FR2999081B1 (fr) | 2012-12-06 | 2015-02-27 | Hra Pharma Lab | Dispersion solide d'un modulateur selectif du recepteur a la progesterone |
CN103006568A (zh) * | 2013-01-05 | 2013-04-03 | 中国科学院苏州纳米技术与纳米仿生研究所 | 非洛地平固态分散物及其制备方法 |
WO2016031651A1 (ja) | 2014-08-29 | 2016-03-03 | 花王株式会社 | 難溶解性ポリフェノール類を含有する固体分散体の製造方法 |
JP6972623B2 (ja) | 2016-04-26 | 2021-11-24 | 三菱ケミカル株式会社 | 固体分散体用基剤、それを用いた固体分散体の製造方法及び固体分散体 |
-
2017
- 2017-11-30 EP EP17204645.0A patent/EP3492070A1/en not_active Withdrawn
-
2018
- 2018-11-29 US US16/767,032 patent/US11413247B2/en active Active
- 2018-11-29 MX MX2020004589A patent/MX2020004589A/es unknown
- 2018-11-29 BR BR112020008646-0A patent/BR112020008646A2/pt unknown
- 2018-11-29 CN CN201880076003.XA patent/CN111405894A/zh active Pending
- 2018-11-29 WO PCT/EP2018/083009 patent/WO2019106090A1/en active Application Filing
- 2018-11-29 DK DK18811797.2T patent/DK3716951T3/da active
- 2018-11-29 PT PT188117972T patent/PT3716951T/pt unknown
- 2018-11-29 EP EP18811797.2A patent/EP3716951B1/en active Active
- 2018-11-29 JP JP2020547302A patent/JP7250029B2/ja active Active
- 2018-11-29 SG SG11202004062WA patent/SG11202004062WA/en unknown
- 2018-11-29 SI SI201830626T patent/SI3716951T1/sl unknown
- 2018-11-29 PL PL18811797T patent/PL3716951T3/pl unknown
- 2018-11-29 ES ES18811797T patent/ES2910012T3/es active Active
- 2018-11-29 AU AU2018376566A patent/AU2018376566B2/en active Active
- 2018-11-29 HU HUE18811797A patent/HUE058088T2/hu unknown
-
2020
- 2020-04-30 IL IL274348A patent/IL274348A/en unknown
- 2020-05-04 CL CL2020001176A patent/CL2020001176A1/es unknown
Also Published As
Publication number | Publication date |
---|---|
HUE058088T2 (hu) | 2022-06-28 |
WO2019106090A1 (en) | 2019-06-06 |
PT3716951T (pt) | 2022-04-06 |
ES2910012T3 (es) | 2022-05-11 |
EP3492070A1 (en) | 2019-06-05 |
CN111405894A (zh) | 2020-07-10 |
PL3716951T3 (pl) | 2022-06-06 |
AU2018376566B2 (en) | 2023-11-30 |
SI3716951T1 (sl) | 2022-06-30 |
EP3716951B1 (en) | 2022-01-05 |
US20200368165A1 (en) | 2020-11-26 |
BR112020008646A2 (pt) | 2020-10-27 |
RU2020121500A (ru) | 2021-12-30 |
AU2018376566A1 (en) | 2020-04-23 |
JP7250029B2 (ja) | 2023-03-31 |
IL274348A (en) | 2020-06-30 |
MX2020004589A (es) | 2022-08-11 |
US11413247B2 (en) | 2022-08-16 |
RU2020121500A3 (da) | 2022-04-05 |
SG11202004062WA (en) | 2020-06-29 |
CL2020001176A1 (es) | 2020-10-30 |
JP2021504487A (ja) | 2021-02-15 |
EP3716951A1 (en) | 2020-10-07 |
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