DK364782A - Cyclophosphamid-derivater, deres fremstilling og anvendelse - Google Patents

Cyclophosphamid-derivater, deres fremstilling og anvendelse Download PDF

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Publication number
DK364782A
DK364782A DK364782A DK364782A DK364782A DK 364782 A DK364782 A DK 364782A DK 364782 A DK364782 A DK 364782A DK 364782 A DK364782 A DK 364782A DK 364782 A DK364782 A DK 364782A
Authority
DK
Denmark
Prior art keywords
preparation
cyclophosphamide derivatives
cyclophosphamide
derivatives
Prior art date
Application number
DK364782A
Other languages
English (en)
Inventor
Hans Joerg Eibl
Cenek Kolar
Friedrich Robert Seiler
Hans-Harald Sedlacek
Original Assignee
Max Planck Gesellschaft
Behringwerke Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Max Planck Gesellschaft, Behringwerke Ag filed Critical Max Planck Gesellschaft
Publication of DK364782A publication Critical patent/DK364782A/da

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Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C247/00Compounds containing azido groups
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07FACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00Compounds containing elements of Groups 5 or 15 of the Periodic System
    • C07F9/02Phosphorus compounds
    • C07F9/547Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom
    • C07F9/6564Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom having phosphorus atoms, with or without nitrogen, oxygen, sulfur, selenium or tellurium atoms, as ring hetero atoms
    • C07F9/6581Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom having phosphorus atoms, with or without nitrogen, oxygen, sulfur, selenium or tellurium atoms, as ring hetero atoms having phosphorus and nitrogen atoms with or without oxygen or sulfur atoms, as ring hetero atoms
    • C07F9/6584Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom having phosphorus atoms, with or without nitrogen, oxygen, sulfur, selenium or tellurium atoms, as ring hetero atoms having phosphorus and nitrogen atoms with or without oxygen or sulfur atoms, as ring hetero atoms having one phosphorus atom as ring hetero atom
    • C07F9/65842Cyclic amide derivatives of acids of phosphorus, in which one nitrogen atom belongs to the ring
    • C07F9/65846Cyclic amide derivatives of acids of phosphorus, in which one nitrogen atom belongs to the ring the phosphorus atom being part of a six-membered ring which may be condensed with another ring system
DK364782A 1981-08-14 1982-08-13 Cyclophosphamid-derivater, deres fremstilling og anvendelse DK364782A (da)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE19813132221 DE3132221A1 (de) 1981-08-14 1981-08-14 Neue cyclophosphamid-derivate, verfahren zu ihrer herstellung und ihre verwendung

Publications (1)

Publication Number Publication Date
DK364782A true DK364782A (da) 1983-02-15

Family

ID=6139355

Family Applications (1)

Application Number Title Priority Date Filing Date
DK364782A DK364782A (da) 1981-08-14 1982-08-13 Cyclophosphamid-derivater, deres fremstilling og anvendelse

Country Status (8)

Country Link
EP (1) EP0072531A1 (da)
JP (1) JPS5841892A (da)
AU (1) AU8717082A (da)
DE (1) DE3132221A1 (da)
DK (1) DK364782A (da)
ES (1) ES8400752A1 (da)
PT (1) PT75416B (da)
ZA (1) ZA825876B (da)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3225227A1 (de) * 1982-07-06 1984-01-12 Max Planck Gesellschaft zur Förderung der Wissenschaften e.V., 3400 Göttingen Derivate des n.n-bis-(2-chlor-aethyl)-phosphorsaeureamids
ZA851062B (en) * 1984-03-01 1985-11-27 Asta Werke Ag Chem Fab Salts of oxazaphosphorine derivatives and process for their production
FR2684102B1 (fr) * 1991-11-21 1994-03-11 Etat Francais Delegue Armement Procede de preparation de polyazidoalcools ainsi que de polyaminoalcools et polyazidothiols derives de ceux-ci.
EP1634886A3 (en) * 1999-03-05 2006-03-29 Metabasis Therapeutics, Inc. Novel phosphorus-containing prodrug
HUP0200260A3 (en) * 1999-03-05 2002-11-28 Metabasis Therapeutics Inc San Novel phosphorus-containing prodrugs, their preparation and their use
US7205404B1 (en) 1999-03-05 2007-04-17 Metabasis Therapeutics, Inc. Phosphorus-containing prodrugs
US6506739B1 (en) 2001-05-01 2003-01-14 Telik, Inc. Bis-(N,N'-bis-(2-haloethyl)amino)phosphoramidates as antitumor agents
FR2968662B1 (fr) * 2010-12-10 2013-11-22 Roussy Inst Gustave Nouveaux derives d'oxazaphosphorines pre-activees, utilisation et methode de preparation
US10449210B2 (en) 2014-02-13 2019-10-22 Ligand Pharmaceuticals Inc. Prodrug compounds and their uses
JP2017520545A (ja) 2014-07-02 2017-07-27 リガンド・ファーマシューティカルズ・インコーポレイテッド プロドラッグ化合物およびそれらの使用

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NL222157A (da) * 1956-12-20
JPS5230519B2 (da) * 1972-04-05 1977-08-09
PL100390B1 (pl) * 1975-10-06 1978-09-30 Sposob wytwarzania 2-tlenku-2-/bis/2-chloroetylo/-amino/-1-/okso-3-aza-2-fosfacykloheksanu/cyklofosfamidu/o czynnosci optycznej

Also Published As

Publication number Publication date
ES514852A0 (es) 1983-11-01
PT75416B (de) 1985-05-31
DE3132221A1 (de) 1983-05-19
ES8400752A1 (es) 1983-11-01
PT75416A (de) 1982-09-01
JPS5841892A (ja) 1983-03-11
EP0072531A1 (de) 1983-02-23
ZA825876B (en) 1983-06-29
AU8717082A (en) 1983-02-17

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