DK364782A - CYCLOPHOSPHAMIDE DERIVATIVES, THEIR PREPARATION AND USE - Google Patents

CYCLOPHOSPHAMIDE DERIVATIVES, THEIR PREPARATION AND USE Download PDF

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Publication number
DK364782A
DK364782A DK364782A DK364782A DK364782A DK 364782 A DK364782 A DK 364782A DK 364782 A DK364782 A DK 364782A DK 364782 A DK364782 A DK 364782A DK 364782 A DK364782 A DK 364782A
Authority
DK
Denmark
Prior art keywords
preparation
cyclophosphamide derivatives
cyclophosphamide
derivatives
Prior art date
Application number
DK364782A
Other languages
Danish (da)
Inventor
Hans Joerg Eibl
Cenek Kolar
Friedrich Robert Seiler
Hans-Harald Sedlacek
Original Assignee
Max Planck Gesellschaft
Behringwerke Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Max Planck Gesellschaft, Behringwerke Ag filed Critical Max Planck Gesellschaft
Publication of DK364782A publication Critical patent/DK364782A/en

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C247/00—Compounds containing azido groups
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
    • C07F9/02—Phosphorus compounds
    • C07F9/547—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom
    • C07F9/6564—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom having phosphorus atoms, with or without nitrogen, oxygen, sulfur, selenium or tellurium atoms, as ring hetero atoms
    • C07F9/6581—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom having phosphorus atoms, with or without nitrogen, oxygen, sulfur, selenium or tellurium atoms, as ring hetero atoms having phosphorus and nitrogen atoms with or without oxygen or sulfur atoms, as ring hetero atoms
    • C07F9/6584—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom having phosphorus atoms, with or without nitrogen, oxygen, sulfur, selenium or tellurium atoms, as ring hetero atoms having phosphorus and nitrogen atoms with or without oxygen or sulfur atoms, as ring hetero atoms having one phosphorus atom as ring hetero atom
    • C07F9/65842—Cyclic amide derivatives of acids of phosphorus, in which one nitrogen atom belongs to the ring
    • C07F9/65846—Cyclic amide derivatives of acids of phosphorus, in which one nitrogen atom belongs to the ring the phosphorus atom being part of a six-membered ring which may be condensed with another ring system

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  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Molecular Biology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
DK364782A 1981-08-14 1982-08-13 CYCLOPHOSPHAMIDE DERIVATIVES, THEIR PREPARATION AND USE DK364782A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE19813132221 DE3132221A1 (en) 1981-08-14 1981-08-14 NEW CYCLOPHOSPHAMIDE DERIVATIVES, METHOD FOR THE PRODUCTION THEREOF AND THEIR USE

Publications (1)

Publication Number Publication Date
DK364782A true DK364782A (en) 1983-02-15

Family

ID=6139355

Family Applications (1)

Application Number Title Priority Date Filing Date
DK364782A DK364782A (en) 1981-08-14 1982-08-13 CYCLOPHOSPHAMIDE DERIVATIVES, THEIR PREPARATION AND USE

Country Status (8)

Country Link
EP (1) EP0072531A1 (en)
JP (1) JPS5841892A (en)
AU (1) AU8717082A (en)
DE (1) DE3132221A1 (en)
DK (1) DK364782A (en)
ES (1) ES514852A0 (en)
PT (1) PT75416B (en)
ZA (1) ZA825876B (en)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3225227A1 (en) * 1982-07-06 1984-01-12 Max Planck Gesellschaft zur Förderung der Wissenschaften e.V., 3400 Göttingen DERIVATIVES OF N.N-BIS- (2-CHLORINE-AETHYL) -PHOSPHORSAEUREAMID
ZA851062B (en) * 1984-03-01 1985-11-27 Asta Werke Ag Chem Fab Salts of oxazaphosphorine derivatives and process for their production
FR2684102B1 (en) * 1991-11-21 1994-03-11 Etat Francais Delegue Armement PROCESS FOR THE PREPARATION OF POLYAZIDOALCOOLS AS WELL AS POLYAMINOALCOOLS AND POLYAZIDOTHIOLS DERIVED THEREFROM.
EP1634886A3 (en) * 1999-03-05 2006-03-29 Metabasis Therapeutics, Inc. Novel phosphorus-containing prodrug
ES2272268T3 (en) * 1999-03-05 2007-05-01 Metabasis Therapeutics, Inc. NEW PROFARMS THAT CONTAIN PHOSPHORUS.
US7205404B1 (en) 1999-03-05 2007-04-17 Metabasis Therapeutics, Inc. Phosphorus-containing prodrugs
US6506739B1 (en) 2001-05-01 2003-01-14 Telik, Inc. Bis-(N,N'-bis-(2-haloethyl)amino)phosphoramidates as antitumor agents
FR2968662B1 (en) * 2010-12-10 2013-11-22 Roussy Inst Gustave NOVEL PRE-ACTIVE OXAZAPHOSPHORINE DERIVATIVES, USE AND METHOD OF PREPARATION
EP3623364A1 (en) 2014-02-13 2020-03-18 Ligand Pharmaceuticals, Inc. Prodrug compounds and their uses
CN106687118A (en) 2014-07-02 2017-05-17 配体药物公司 Prodrug compounds and uses thereof
JP2021509907A (en) 2018-01-09 2021-04-08 リガンド・ファーマシューティカルズ・インコーポレイテッド Acetal compounds and their therapeutic use

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NL99688C (en) * 1956-12-20
JPS5230519B2 (en) * 1972-04-05 1977-08-09
PL100390B1 (en) * 1975-10-06 1978-09-30 METHOD FOR THE PRODUCTION OF 2-OXIDE-2- / BIS / 2-CHLOROETHYL / -AMINO / -1- / OXO-3-AZA-2-PHOSPHACYCLOHEXANE / CYCLOPHOSPHAMIDE / OPTICAL

Also Published As

Publication number Publication date
ES8400752A1 (en) 1983-11-01
AU8717082A (en) 1983-02-17
EP0072531A1 (en) 1983-02-23
ZA825876B (en) 1983-06-29
PT75416B (en) 1985-05-31
JPS5841892A (en) 1983-03-11
ES514852A0 (en) 1983-11-01
DE3132221A1 (en) 1983-05-19
PT75416A (en) 1982-09-01

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