DK3591042T5 - PRRS-virusvariant, cDNA-klon af europæisk PRRS-virus samt anvendelser deraf - Google Patents
PRRS-virusvariant, cDNA-klon af europæisk PRRS-virus samt anvendelser deraf Download PDFInfo
- Publication number
- DK3591042T5 DK3591042T5 DK19165389.8T DK19165389T DK3591042T5 DK 3591042 T5 DK3591042 T5 DK 3591042T5 DK 19165389 T DK19165389 T DK 19165389T DK 3591042 T5 DK3591042 T5 DK 3591042T5
- Authority
- DK
- Denmark
- Prior art keywords
- prrs virus
- cdna clone
- european
- variant
- virus variant
- Prior art date
Links
- 208000005342 Porcine Reproductive and Respiratory Syndrome Diseases 0.000 title 2
- 241000700605 Viruses Species 0.000 title 2
- 239000002299 complementary DNA Substances 0.000 title 1
Classifications
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/12—Viral antigens
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/14—Antivirals for RNA viruses
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/04—Immunostimulants
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/005—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from viruses
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
- C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
- C12N15/85—Vectors or expression systems specially adapted for eukaryotic hosts for animal cells
- C12N15/86—Viral vectors
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N7/00—Viruses; Bacteriophages; Compositions thereof; Preparation or purification thereof
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/02—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving viable microorganisms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/51—Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
- A61K2039/525—Virus
- A61K2039/5254—Virus avirulent or attenuated
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/55—Medicinal preparations containing antigens or antibodies characterised by the host/recipient, e.g. newborn with maternal antibodies
- A61K2039/552—Veterinary vaccine
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2770/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses positive-sense
- C12N2770/00011—Details
- C12N2770/10011—Arteriviridae
- C12N2770/10021—Viruses as such, e.g. new isolates, mutants or their genomic sequences
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2770/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses positive-sense
- C12N2770/00011—Details
- C12N2770/10011—Arteriviridae
- C12N2770/10034—Use of virus or viral component as vaccine, e.g. live-attenuated or inactivated virus, VLP, viral protein
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2770/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses positive-sense
- C12N2770/00011—Details
- C12N2770/10011—Arteriviridae
- C12N2770/10041—Use of virus, viral particle or viral elements as a vector
- C12N2770/10043—Use of virus, viral particle or viral elements as a vector viral genome or elements thereof as genetic vector
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
- G01N2333/005—Assays involving biological materials from specific organisms or of a specific nature from viruses
- G01N2333/08—RNA viruses
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Genetics & Genomics (AREA)
- Organic Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Wood Science & Technology (AREA)
- Zoology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Health & Medical Sciences (AREA)
- Biotechnology (AREA)
- General Engineering & Computer Science (AREA)
- Virology (AREA)
- Biomedical Technology (AREA)
- Microbiology (AREA)
- Biochemistry (AREA)
- Immunology (AREA)
- Medicinal Chemistry (AREA)
- Molecular Biology (AREA)
- Biophysics (AREA)
- Physics & Mathematics (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Plant Pathology (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Mycology (AREA)
- Analytical Chemistry (AREA)
- Gastroenterology & Hepatology (AREA)
- Epidemiology (AREA)
- Communicable Diseases (AREA)
- Oncology (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Peptides Or Proteins (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP13199177 | 2013-12-20 | ||
| EP14175691 | 2014-07-03 | ||
| EP14827219.8A EP3083947B1 (en) | 2013-12-20 | 2014-12-19 | Prrs virus variant, european prrs virus cdna clone, and uses thereof |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| DK3591042T3 DK3591042T3 (da) | 2023-04-17 |
| DK3591042T5 true DK3591042T5 (da) | 2024-09-02 |
Family
ID=52347295
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DK14827219.8T DK3083947T3 (da) | 2013-12-20 | 2014-12-19 | Prrs-virusvariant, cdna-klon af europæisk prrs-virus, samt anvendelser deraf |
| DK19165389.8T DK3591042T5 (da) | 2013-12-20 | 2014-12-19 | PRRS-virusvariant, cDNA-klon af europæisk PRRS-virus samt anvendelser deraf |
Family Applications Before (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DK14827219.8T DK3083947T3 (da) | 2013-12-20 | 2014-12-19 | Prrs-virusvariant, cdna-klon af europæisk prrs-virus, samt anvendelser deraf |
Country Status (13)
| Country | Link |
|---|---|
| US (2) | US10010601B2 (OSRAM) |
| EP (2) | EP3083947B1 (OSRAM) |
| JP (3) | JP6886291B2 (OSRAM) |
| KR (2) | KR102270344B1 (OSRAM) |
| CN (1) | CN105829528B (OSRAM) |
| AU (2) | AU2014369774B2 (OSRAM) |
| CA (1) | CA2930042C (OSRAM) |
| DK (2) | DK3083947T3 (OSRAM) |
| EA (1) | EA039060B1 (OSRAM) |
| ES (2) | ES2940691T3 (OSRAM) |
| HU (1) | HUE061768T2 (OSRAM) |
| MX (2) | MX2020010248A (OSRAM) |
| WO (1) | WO2015092058A1 (OSRAM) |
Families Citing this family (14)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| KR101983980B1 (ko) | 2011-02-17 | 2019-05-30 | 베링거잉겔하임베트메디카게엠베하 | Ｐｒｒｓｖ의 상업적 규모의 제조 방법 |
| MY161198A (en) | 2011-02-17 | 2017-04-14 | Boehringer Ingelheim Vetmedica Gmbh | Novel european prrsv strain |
| ES2940691T3 (es) | 2013-12-20 | 2023-05-10 | Boehringer Ingelheim Vetmedica Gmbh | Variante de virus PRRS, clon de ADNc de virus PRRS europeo y usos de los mismos |
| EP3493838A1 (en) | 2016-08-05 | 2019-06-12 | Hipra Scientific, S.L.U. | PORCINE REPRODUCTIVE AND RESPIRATORY SYNDROME VIRUS cDNA CLONE AND USES THEREOF |
| WO2020138761A1 (ko) * | 2018-12-27 | 2020-07-02 | 주식회사 바이오포아 | 돼지 생식기 및 호흡기 증후군 바이러스의 키메라 바이러스 및 이를 이용한 백신 |
| KR102335864B1 (ko) * | 2018-12-27 | 2021-12-06 | 주식회사 바이오포아 | 돼지 생식기 및 호흡기 증후군 바이러스의 키메라 바이러스 및 이를 이용한 백신 |
| EP4021577A1 (en) * | 2019-08-29 | 2022-07-06 | Elanco Us Inc. | Porcine reproductive and respiratory syndrome vaccine virus |
| CN110894243B (zh) * | 2019-12-16 | 2021-07-13 | 中国农业大学 | 一种猪蓝耳病毒嵌合抗原以及检测猪蓝耳病毒抗体的胶体金免疫层析试纸条 |
| AU2020417800A1 (en) * | 2019-12-31 | 2022-07-14 | Elixirgen Therapeutics, Inc. | Temperature-based transient delivery of nucleic acids and proteins to cells and tissues |
| JP2021153692A (ja) * | 2020-03-25 | 2021-10-07 | 株式会社三共 | 遊技機 |
| KR102319508B1 (ko) * | 2020-07-27 | 2021-10-28 | 연세대학교 산학협력단 | 인체 감염형 낙타 유래 메르스코로나바이러스 검출용 바이오마커 및 이의 용도 |
| CN113969267B (zh) * | 2021-11-15 | 2024-02-27 | 中国农业大学 | 一种猪繁殖与呼吸综合征突变病毒及其构建方法与应用 |
| WO2024077281A2 (en) * | 2022-10-06 | 2024-04-11 | Cornell University | Genotyping and sequencing assays for prrsv |
| KR20240146158A (ko) * | 2023-03-27 | 2024-10-08 | 주식회사 케어사이드 | 돼지생식기호흡기증후군 키메릭 바이러스 및 이를 이용한 백신 조성물 |
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| US5695766A (en) | 1992-10-30 | 1997-12-09 | Iowa State University Research Foundation | Highly virulent porcine reproductive and respiratory syndrome viruses which produce lesions in pigs and vaccines that protect pigs against said syndrome |
| ES2074950B1 (es) | 1993-09-17 | 1996-03-16 | Iberica Cyanamid | Vacuna para la prevencion de la enfermedad reproductiva y respiratoria de la cerda. |
| DK0676467T3 (da) | 1994-04-11 | 2002-01-21 | Akzo Nobel Nv | Europæiske vaccinestammer af det porcine reproduktive respiratoriske syndromvirus (PRRSV) |
| DK53595A (da) | 1994-05-13 | 1995-11-14 | Iberica Cyanamid | Rekombinante PRRSV-proteiner, diagnostiske kits og vaccine indeholdende sådanne rekombinante PRRSV-proteiner |
| PT732340E (pt) | 1995-03-14 | 2004-09-30 | Akzo Nobel Nv | Expressao de polipeptidos do virus da sindrome reprodutiva e respiratoria porcina na mesma celula |
| ES2102971B1 (es) | 1996-01-25 | 1998-03-01 | Hipra Lab Sa | Nueva cepa atenuada del virus causante del sindrome respiratorio y reproductivo porcino (prrs), las vacunas y medios de diagnostico obtenibles con la misma y los procedimientos para su obtencion. |
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| DK0835930T3 (da) | 1996-10-09 | 2001-06-18 | Akzo Nobel Nv | Europæiske vaccinestammer af porcint reproduktions- og respirationssyndrom-virus. (PRRSV) |
| US20040224327A1 (en) | 1996-10-30 | 2004-11-11 | Meulenberg Johanna Jacoba Maria | Infectious clones of RNA viruses and vaccines and diagnostic assays derived thereof |
| EP0839912A1 (en) | 1996-10-30 | 1998-05-06 | Instituut Voor Dierhouderij En Diergezondheid (Id-Dlo) | Infectious clones of RNA viruses and vaccines and diagnostic assays derived thereof |
| RU2220978C2 (ru) | 1997-05-06 | 2004-01-10 | Стихтинг Динст Ландбаувкюндиг Ондерзук | Пептид, индуцирующий образование антител, которые реагируют с двумя различными изолятами вррсс (варианты), иммуногенная композиция, вакцина для профилактики заражения репродуктивно-респираторным синдромом свиней, антитело, диагностический набор (варианты) |
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| EP1397498A1 (en) | 2001-05-21 | 2004-03-17 | ID-Lelystad, Instituut voor Dierhouderij en Diergezondheid B.V. | Delections in arterivirus replicons |
| ATE557082T1 (de) | 2002-04-05 | 2012-05-15 | Boehringer Ingelheim Vetmed | Sequenz positionen zur anpassung bei prrsv |
| US7722878B2 (en) | 2004-06-17 | 2010-05-25 | Boehringer Ingelheim Vetmedica, Inc. | PRRSV subunit vaccines |
| US7632636B2 (en) | 2004-09-21 | 2009-12-15 | Boehringer Ingelheim Vetmedica, Inc. | Porcine reproductive and respiratory syndrome isolates and methods of use |
| KR20070096019A (ko) | 2005-01-13 | 2007-10-01 | 베링거잉겔하임베트메디카게엠베하 | 향상된 ｐｒｒｓ 백신 |
| WO2008121958A1 (en) | 2007-04-02 | 2008-10-09 | Boehringer Ingelheim Vetmedica, Inc. | Use of prrsv vaccines to reduce pcv2 viremia |
| CN101848995A (zh) * | 2007-06-25 | 2010-09-29 | 南达科他州立大学 | 重组的北美1型猪繁殖与呼吸综合征病毒及使用方法 |
| KR101653177B1 (ko) | 2008-08-25 | 2016-09-01 | 베링거잉겔하임베트메디카인코퍼레이티드 | 고병원성 돼지 생식기 및 호흡기 증후군(ｈｐ ｐｒｒｓ)에 대한 백신 |
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| MY161198A (en) * | 2011-02-17 | 2017-04-14 | Boehringer Ingelheim Vetmedica Gmbh | Novel european prrsv strain |
| KR101983980B1 (ko) | 2011-02-17 | 2019-05-30 | 베링거잉겔하임베트메디카게엠베하 | Ｐｒｒｓｖ의 상업적 규모의 제조 방법 |
| EP2737058A1 (en) | 2011-07-29 | 2014-06-04 | Boehringer Ingelheim Vetmedica GmbH | INFECTIOUS cDNA CLONE OF EUROPEAN PRRS VIRUS AND USES THEREOF |
| JP6260972B2 (ja) * | 2012-02-14 | 2018-01-17 | メリアル インコーポレイテッド | 狂犬病タンパク質及びｏｘ４０タンパク質の両方を発現する組換えポックスウイルスベクター並びに前記ベクターから製造されるワクチン |
| CA2872789C (en) * | 2012-05-17 | 2019-09-03 | Zoetis Llc | Effective vaccination against porcine reproductive and respiratory syndrome (prrs) virus prior to weaning |
| WO2014150822A2 (en) | 2013-03-15 | 2014-09-25 | Boehringer Ingelheim Vetmedica, Inc. | Porcine reproductive and respiratory syndrome virus, compositions, vaccine and methods of use |
| CN105829906B (zh) * | 2013-12-19 | 2020-11-03 | 皇家飞利浦有限公司 | 具有水/脂肪分离的相位敏感的反转恢复mri |
| ES2940691T3 (es) * | 2013-12-20 | 2023-05-10 | Boehringer Ingelheim Vetmedica Gmbh | Variante de virus PRRS, clon de ADNc de virus PRRS europeo y usos de los mismos |
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2014
- 2014-12-19 ES ES19165389T patent/ES2940691T3/es active Active
- 2014-12-19 JP JP2016540591A patent/JP6886291B2/ja active Active
- 2014-12-19 KR KR1020167019672A patent/KR102270344B1/ko active Active
- 2014-12-19 MX MX2020010248A patent/MX2020010248A/es unknown
- 2014-12-19 MX MX2016007737A patent/MX375528B/es active IP Right Grant
- 2014-12-19 ES ES14827219T patent/ES2729838T3/es active Active
- 2014-12-19 US US15/105,760 patent/US10010601B2/en active Active
- 2014-12-19 AU AU2014369774A patent/AU2014369774B2/en active Active
- 2014-12-19 WO PCT/EP2014/078929 patent/WO2015092058A1/en not_active Ceased
- 2014-12-19 EP EP14827219.8A patent/EP3083947B1/en active Active
- 2014-12-19 EP EP19165389.8A patent/EP3591042B1/en active Active
- 2014-12-19 EA EA201600476A patent/EA039060B1/ru unknown
- 2014-12-19 CA CA2930042A patent/CA2930042C/en active Active
- 2014-12-19 DK DK14827219.8T patent/DK3083947T3/da active
- 2014-12-19 DK DK19165389.8T patent/DK3591042T5/da active
- 2014-12-19 KR KR1020217019360A patent/KR102446025B1/ko active Active
- 2014-12-19 CN CN201480068965.2A patent/CN105829528B/zh active Active
- 2014-12-19 HU HUE19165389A patent/HUE061768T2/hu unknown
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2018
- 2018-06-01 US US15/995,560 patent/US10639364B2/en active Active
-
2019
- 2019-12-20 JP JP2019230014A patent/JP2020054380A/ja not_active Withdrawn
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2021
- 2021-02-25 AU AU2021201224A patent/AU2021201224B2/en active Active
- 2021-03-24 JP JP2021049537A patent/JP7158523B2/ja active Active
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