DK3555268T3 - Fremgangsmåder til produktion af fedtalkoholer og derivater deraf i gær - Google Patents

Fremgangsmåder til produktion af fedtalkoholer og derivater deraf i gær Download PDF

Info

Publication number
DK3555268T3
DK3555268T3 DK17825464.5T DK17825464T DK3555268T3 DK 3555268 T3 DK3555268 T3 DK 3555268T3 DK 17825464 T DK17825464 T DK 17825464T DK 3555268 T3 DK3555268 T3 DK 3555268T3
Authority
DK
Denmark
Prior art keywords
yeast
derivatives
processes
production
fatty alcohols
Prior art date
Application number
DK17825464.5T
Other languages
English (en)
Inventor
Carina Holkenbrink
Marie Inger Dam
Christer Löfstedt
Irina Borodina
Original Assignee
Univ Danmarks Tekniske
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Univ Danmarks Tekniske filed Critical Univ Danmarks Tekniske
Application granted granted Critical
Publication of DK3555268T3 publication Critical patent/DK3555268T3/da

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09Recombinant DNA-technology
    • C12N15/63Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/79Vectors or expression systems specially adapted for eukaryotic hosts
    • C12N15/80Vectors or expression systems specially adapted for eukaryotic hosts for fungi
    • C12N15/81Vectors or expression systems specially adapted for eukaryotic hosts for fungi for yeasts
    • C12N15/815Vectors or expression systems specially adapted for eukaryotic hosts for fungi for yeasts for yeasts other than Saccharomyces
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09Recombinant DNA-technology
    • C12N15/11DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
    • C12N15/52Genes encoding for enzymes or proenzymes
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/0004Oxidoreductases (1.)
    • C12N9/0008Oxidoreductases (1.) acting on the aldehyde or oxo group of donors (1.2)
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/0004Oxidoreductases (1.)
    • C12N9/0071Oxidoreductases (1.) acting on paired donors with incorporation of molecular oxygen (1.14)
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12PFERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P7/00Preparation of oxygen-containing organic compounds
    • C12P7/02Preparation of oxygen-containing organic compounds containing a hydroxy group
    • C12P7/04Preparation of oxygen-containing organic compounds containing a hydroxy group acyclic
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12YENZYMES
    • C12Y114/00Oxidoreductases acting on paired donors, with incorporation or reduction of molecular oxygen (1.14)
    • C12Y114/19Oxidoreductases acting on paired donors, with incorporation or reduction of molecular oxygen (1.14) with oxidation of a pair of donors resulting in the reduction of molecular oxygen to two molecules of water (1.14.19)
    • C12Y114/19001Stearoyl-CoA 9-desaturase (1.14.19.1), i.e. DELTA9-desaturase
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02PCLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00Technologies relating to chemical industry
    • Y02P20/50Improvements relating to the production of bulk chemicals
    • Y02P20/582Recycling of unreacted starting or intermediate materials

Landscapes

  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Engineering & Computer Science (AREA)
  • Organic Chemistry (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biotechnology (AREA)
  • General Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Biochemistry (AREA)
  • Microbiology (AREA)
  • General Health & Medical Sciences (AREA)
  • Molecular Biology (AREA)
  • Biophysics (AREA)
  • Physics & Mathematics (AREA)
  • Plant Pathology (AREA)
  • Mycology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
DK17825464.5T 2016-12-16 2017-12-15 Fremgangsmåder til produktion af fedtalkoholer og derivater deraf i gær DK3555268T3 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP16204769 2016-12-16
PCT/EP2017/083021 WO2018109163A1 (en) 2016-12-16 2017-12-15 Methods for producing fatty alcohols and derivatives thereof in yeast

Publications (1)

Publication Number Publication Date
DK3555268T3 true DK3555268T3 (da) 2021-08-30

Family

ID=57609699

Family Applications (1)

Application Number Title Priority Date Filing Date
DK17825464.5T DK3555268T3 (da) 2016-12-16 2017-12-15 Fremgangsmåder til produktion af fedtalkoholer og derivater deraf i gær

Country Status (9)

Country Link
US (1) US11345922B2 (da)
EP (2) EP3555268B1 (da)
CN (1) CN110300799B (da)
BR (1) BR112019012266B1 (da)
DE (1) DE17825464T1 (da)
DK (1) DK3555268T3 (da)
ES (1) ES2888232T3 (da)
HU (1) HUE055982T2 (da)
WO (1) WO2018109163A1 (da)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP6737885B2 (ja) 2015-11-18 2020-08-12 プロヴィヴィ インコーポレイテッド 昆虫フェロモンの生成のための微生物及び関連する化合物
EP3635124A4 (en) 2017-05-17 2021-03-31 Provivi, Inc. MICRO-ORGANISMS INTENDED FOR THE PRODUCTION OF INSECT PHEROMONES AND ASSOCIATED COMPOUNDS
WO2020169389A1 (en) 2019-02-19 2020-08-27 Biophero Aps Methods and cell factories for producing insect pheromones
CA3151980A1 (en) 2019-10-22 2021-04-29 Bettina Lorantfy Improved methods for production, recovery and secretion of hydrophobic compounds in a fermentation
US20230031596A1 (en) * 2019-12-11 2023-02-02 Provivi, Inc. Biosynthesis of insect pheromones and precursors thereof
CA3161539A1 (en) 2019-12-20 2021-06-24 Irina BORODINA Yeast cells and methods for production of e8,e10-dodecadienyl coenzyme a, codlemone and derivatives thereof
CN114807240B (zh) * 2021-01-21 2024-02-06 深圳市第二人民医院(深圳市转化医学研究院) 一种连接有适配体的模板分子及其试剂盒
KR20240019132A (ko) 2021-05-10 2024-02-14 에프엠씨 애그리컬쳐럴 솔루션즈 에이/에스 효소 활성 및 곤충 페로몬의 생산을 증가시키기 위한 개선된 방법 및 세포
WO2023275361A1 (en) 2021-07-02 2023-01-05 Biophero Aps Methods and yeast cells for production of desaturated compounds
WO2023275374A1 (en) 2021-07-02 2023-01-05 Biophero Aps Methods and yeast cells for production of desaturated compounds
AU2022321753A1 (en) 2021-08-06 2024-01-25 FMC Agricultural Solutions A/S Method for producing fatty aldehydes and derivatives thereof
US20230242944A1 (en) * 2022-01-31 2023-08-03 Isca Technologies, Inc. Methods for production of diatraea saccharalis pheromone precursors
US20230242945A1 (en) * 2022-01-31 2023-08-03 Isca Technologies, Inc. Methods for production of amyelois transitella pheromone precursor

Family Cites Families (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5876994A (en) 1995-11-16 1999-03-02 Cornell Research Foundation, Inc. Pheromone desaturases
US6593299B1 (en) 1999-04-21 2003-07-15 University Of Florida Research Foundation, Inc. Compositions and methods for controlling pests
DE10208812A1 (de) 2002-03-01 2003-09-11 Basf Plant Science Gmbh Verfahren zur Herstellung von ungesättigten Fettsäuren
ES2204328B1 (es) 2002-10-04 2005-09-01 Consejo Sup. De Invest. Cientificas Procedimiento de produccion de acidos grasos polinsaturados con levaduras por incorporacion de sustratos olefinicos o acetilenicos.
CA2701094A1 (en) 2007-10-03 2009-04-09 E. I. Du Pont De Nemours And Company Optimized strains of yarrowia lipolytica for high eicosapentaenoic acid production
PL2655612T3 (pl) 2010-12-23 2017-12-29 Shell Internationale Research Maatschappij B.V. Czynniki uszkadzające geny produkujące pochodne tłuszczowego acylo-coa
US20120164686A1 (en) 2010-12-23 2012-06-28 Codexis, Inc. Yeast promoters
WO2013096092A1 (en) 2011-12-20 2013-06-27 Codexis, Inc. Production of saturated fatty alcohols from engineered microorganisms
CN102795997A (zh) 2012-08-21 2012-11-28 昆明博鸿生物科技有限公司 小菜蛾性信息素化合物的合成方法
WO2015013674A2 (en) 2013-07-25 2015-01-29 The Regents Of The University Of California A yeast cell modified to overproduce fatty acid and fatty acid-derived compounds
EP3058078B1 (en) 2013-10-18 2019-10-09 Biopetrolia AB Engineering of hydrocarbon metabolism in yeast
WO2015171057A1 (en) 2014-05-06 2015-11-12 Per Hofvander Production of insect pheromone precursors in plants
DK3313997T3 (da) 2015-06-26 2020-04-27 Univ Danmarks Tekniske Fremgangsmåde til fremstilling af mølferomoner i gær
JP6737885B2 (ja) * 2015-11-18 2020-08-12 プロヴィヴィ インコーポレイテッド 昆虫フェロモンの生成のための微生物及び関連する化合物

Also Published As

Publication number Publication date
EP3916087A1 (en) 2021-12-01
EP3555268A1 (en) 2019-10-23
ES2888232T3 (es) 2022-01-03
US20190330646A1 (en) 2019-10-31
BR112019012266B1 (pt) 2022-08-30
US11345922B2 (en) 2022-05-31
EP3555268B1 (en) 2021-05-26
BR112019012266A2 (pt) 2020-01-28
HUE055982T2 (hu) 2022-01-28
WO2018109163A1 (en) 2018-06-21
CN110300799A (zh) 2019-10-01
DE17825464T1 (de) 2019-12-19
CN110300799B (zh) 2024-01-19

Similar Documents

Publication Publication Date Title
DK3555268T3 (da) Fremgangsmåder til produktion af fedtalkoholer og derivater deraf i gær
DK3601533T3 (da) Fremgangsmåder til frembringelse af tumorinfiltrerende lymfocytter og anvendelser af samme i immunoterapi
DK3277827T3 (da) Svampeceller og fremgangsmåder til fremstilling af produkter afledt af meget langkædede fedtsyrer
DK3507461T3 (da) Biomimetiske bæreplanslegemer og fremgangsmåder til design og fremstilling heraf
EP3322220A4 (en) METHOD FOR SELECTION OF A CELL AND DEVICE TO BE FILLED THEREWITH
DK3491173T3 (da) Fremgangsmåde og anlæg til fremstilling af methanol
DK3256717T3 (da) Hydroelektrisk/hydrokinetisk turbine og fremgangsmåder til fremstilling og anvendelse deraf
DK3702443T3 (da) Sammensætninger og fremgangsmåder til opformering og dyrkning af epiteliale stamceller
DK3313997T3 (da) Fremgangsmåde til fremstilling af mølferomoner i gær
DK3368613T3 (da) Matteringsmiddel og fremgangsmåde til fremstilling deraf
DK3221257T3 (da) Fremgangsmåde og anlæg til fremstilling og lagring af hydrogen
EP3093889B8 (en) Solar cell and method of manufacturing the same
DK3555269T3 (da) Fremstilling af umættede fedtalkoholer og umættede fedtacylacetater i gær
DK2955777T3 (da) Brændselscelle og fremgangsmåde til fremstilling af samme
DK3519540T3 (da) Fremgangsmåde til oprensning af animalske og/eller vegetabilske fedtstoffer
EP3327793C0 (en) SOLAR CELL AND ITS MANUFACTURING METHOD
DK3541947T3 (da) Fremgangsmåde til fremstilling af elektrokompetente gærceller og fremgangsmåde til anvendelse af cellerne
DK3153573T3 (da) Mikroorganisme af slægten Corynebacterium til fremstilling af L-arginin og fremgangsmåde til fremstilling af L-arginin under anvendelse af samme
DK3137616T3 (da) Forøgelse af cellulær lipid produktion ved forøgelse af aktiviteten af diacylglycerolacyltransferase og formindskelse af aktiviteten af triacylglycerollipase
DK3346822T3 (da) Agronomisk fremgangsmåde til produktion af grøntsager og svampe
DK3514227T3 (da) Fremgangsmåde til fremstilling af tredimensionel cellestruktur og støtte anvendt til samme
DK3149153T3 (da) Forøgelse af lipidproduktion i olieholdig gær
DK3022361T4 (da) Rambuk og fremgangsmåde til anvendelse deraf
DK3120055T3 (da) Membran og fremgangsmåde til fremstilling deraf
DK3609431T3 (da) Anordninger og fremgangsmåder til at fremme produktionen af kvindelige fostre i æg