DK3548135T3 - Kerne-skal-mikronålsindretninger og anvendelser deraf - Google Patents
Kerne-skal-mikronålsindretninger og anvendelser deraf Download PDFInfo
- Publication number
- DK3548135T3 DK3548135T3 DK17879565.4T DK17879565T DK3548135T3 DK 3548135 T3 DK3548135 T3 DK 3548135T3 DK 17879565 T DK17879565 T DK 17879565T DK 3548135 T3 DK3548135 T3 DK 3548135T3
- Authority
- DK
- Denmark
- Prior art keywords
- core
- needle devices
- shell micro
- micro
- shell
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M37/00—Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin
- A61M37/0015—Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin by using microneedles
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
- A61K31/715—Polysaccharides, i.e. having more than five saccharide radicals attached to each other by glycosidic linkages; Derivatives thereof, e.g. ethers, esters
- A61K31/726—Glycosaminoglycans, i.e. mucopolysaccharides
- A61K31/728—Hyaluronic acid
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/22—Hormones
- A61K38/28—Insulins
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/43—Enzymes; Proenzymes; Derivatives thereof
- A61K38/44—Oxidoreductases (1)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
- A61K47/51—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
- A61K47/54—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic compound
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
- A61K47/69—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the conjugate being characterised by physical or galenical forms, e.g. emulsion, particle, inclusion complex, stent or kit
- A61K47/6955—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the conjugate being characterised by physical or galenical forms, e.g. emulsion, particle, inclusion complex, stent or kit the form being a plaster, a bandage, a dressing or a patch
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
- A61K9/0021—Intradermal administration, e.g. through microneedle arrays or needleless injectors
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M37/00—Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin
- A61M37/0015—Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin by using microneedles
- A61M2037/0046—Solid microneedles
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M37/00—Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin
- A61M37/0015—Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin by using microneedles
- A61M2037/0061—Methods for using microneedles
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Y—ENZYMES
- C12Y101/00—Oxidoreductases acting on the CH-OH group of donors (1.1)
- C12Y101/03—Oxidoreductases acting on the CH-OH group of donors (1.1) with a oxygen as acceptor (1.1.3)
- C12Y101/03004—Glucose oxidase (1.1.3.4)
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Y—ENZYMES
- C12Y111/00—Oxidoreductases acting on a peroxide as acceptor (1.11)
- C12Y111/01—Peroxidases (1.11.1)
- C12Y111/01006—Catalase (1.11.1.6)
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Engineering & Computer Science (AREA)
- Medicinal Chemistry (AREA)
- Epidemiology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Diabetes (AREA)
- Dermatology (AREA)
- Organic Chemistry (AREA)
- Endocrinology (AREA)
- Immunology (AREA)
- Gastroenterology & Hepatology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Zoology (AREA)
- Hematology (AREA)
- General Chemical & Material Sciences (AREA)
- Molecular Biology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Obesity (AREA)
- Emergency Medicine (AREA)
- Wood Science & Technology (AREA)
- Biochemistry (AREA)
- General Engineering & Computer Science (AREA)
- Genetics & Genomics (AREA)
- Anesthesiology (AREA)
- Biomedical Technology (AREA)
- Heart & Thoracic Surgery (AREA)
- Medical Informatics (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Medicinal Preparation (AREA)
- Media Introduction/Drainage Providing Device (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201662430260P | 2016-12-05 | 2016-12-05 | |
| PCT/US2017/064723 WO2018106696A1 (en) | 2016-12-05 | 2017-12-05 | Core-shell microneedle devices and uses thereof |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| DK3548135T3 true DK3548135T3 (da) | 2021-11-22 |
Family
ID=62491316
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DK17879565.4T DK3548135T3 (da) | 2016-12-05 | 2017-12-05 | Kerne-skal-mikronålsindretninger og anvendelser deraf |
Country Status (7)
| Country | Link |
|---|---|
| US (2) | US11697007B2 (https=) |
| EP (2) | EP3548135B1 (https=) |
| JP (1) | JP7232526B2 (https=) |
| CN (1) | CN110167624B (https=) |
| CA (1) | CA3045882A1 (https=) |
| DK (1) | DK3548135T3 (https=) |
| WO (1) | WO2018106696A1 (https=) |
Families Citing this family (20)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DK3548135T3 (da) * | 2016-12-05 | 2021-11-22 | Univ North Carolina State | Kerne-skal-mikronålsindretninger og anvendelser deraf |
| US12109032B1 (en) | 2017-03-11 | 2024-10-08 | Biolinq Incorporated | Methods for achieving an isolated electrical interface between an anterior surface of a microneedle structure and a posterior surface of a support structure |
| US12599337B1 (en) | 2017-08-08 | 2026-04-14 | Biolinq Incorporated | Method and system for confirmation of microneedle-based analyte-selective sensor insertion into viable tissue via electrical interrogation |
| WO2019143293A1 (en) * | 2018-01-16 | 2019-07-25 | Nanyang Technological University | Self-implantable micro-drug-reservoirs for localized and controlled ocular drug delivery |
| US11724941B2 (en) | 2018-02-15 | 2023-08-15 | North Carolina State University | Synthesis of micron and nanoscale carbon spheres and structures using hydrothemal carbonization |
| US20210145984A1 (en) * | 2018-04-13 | 2021-05-20 | North Carolina State University | Ros-responsive microneedle patch for acne vulgaris treatment |
| JP2021533934A (ja) | 2018-08-24 | 2021-12-09 | ノース カロライナ ステート ユニバーシティNorth Carolina State University | 閉ループインスリン送達用のグルコース応答性マトリックスを備えたマイクロニードルアレイパッチ |
| WO2020041694A1 (en) * | 2018-08-24 | 2020-02-27 | North Carolina State University | Stem cell microneedle patch for treating heart diseases |
| EP3852721A4 (en) * | 2018-09-20 | 2022-06-29 | Singapore Health Services Pte Ltd | Conductive microneedle patch for active agent delivery |
| CN109675185A (zh) * | 2019-01-02 | 2019-04-26 | 浙江大学 | 一种苯硼酸水凝胶基糖敏微针贴及其制备方法 |
| JP2021153914A (ja) * | 2020-03-27 | 2021-10-07 | 国立大学法人 東京医科歯科大学 | 薬剤送達デバイスおよびその製造方法 |
| JP2023523952A (ja) | 2020-04-28 | 2023-06-08 | ティコナ・エルエルシー | マイクロニードルアセンブリ |
| KR102740788B1 (ko) * | 2020-07-02 | 2024-12-09 | 연세대학교 산학협력단 | 멀티 레이어 마이크로니들 구조체 및 이의 제조 방법 |
| GB2631618B (en) | 2020-07-29 | 2025-05-14 | Biolinq Incorporated | Continuous analyte monitoring system with microneedle array |
| CN118001218B (zh) * | 2022-11-08 | 2026-03-06 | 沈阳药科大学 | 一种血糖响应型释药可视化长效微针及其制备方法 |
| CN115998850A (zh) * | 2022-12-26 | 2023-04-25 | 中山大学 | 一种尿酸响应性水凝胶微针及其制备方法 |
| CN120857905A (zh) | 2023-02-02 | 2025-10-28 | 比奥林公司 | 用于改善基于微针的连续分析物监测系统的传感器灵敏度的方法 |
| WO2024167986A2 (en) * | 2023-02-10 | 2024-08-15 | Alj Creative Works, Llc | Programmable drug-device microneedle system for the treament of diabetes, obesity, and associated conditions |
| CN117088903B (zh) * | 2023-08-15 | 2026-03-17 | 河南师范大学 | 苯硼酸基两性离子表面活性剂的制备方法及其合成pH响应二聚体分子的应用 |
| CN117159443B (zh) * | 2023-10-19 | 2024-04-19 | 暨南大学 | 原位超分子凝胶微针贴片及其制备方法和应用 |
Family Cites Families (14)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP1469903A2 (en) * | 2001-09-28 | 2004-10-27 | BioValve Technologies, Inc. | Microneedle with membrane |
| EP1453860A2 (en) | 2001-12-02 | 2004-09-08 | Novo Nordisk A/S | Novel glucose-dependant insulins |
| US9549746B2 (en) | 2007-09-28 | 2017-01-24 | The Queen's University Of Belfast | Delivery device and method |
| EP2234644B1 (en) | 2008-01-04 | 2013-07-31 | Biodel, Inc. | Insulin formulations for insulin release as a function of tissue glucose levels |
| WO2010050913A1 (en) | 2008-10-31 | 2010-05-06 | The Brigham And Women's Hospital, Inc. | Vaccination with poxvirus vectors via mechanical epidermal disruption |
| WO2013123492A2 (en) | 2012-02-17 | 2013-08-22 | Massachusetts Institute Of Technology | Glucose-responsive microgels for closed loop insulin delivery |
| US20150352777A1 (en) * | 2013-01-18 | 2015-12-10 | The University Of North Carolina At Chapel Hill | High-throughput manufacturing of microneedles |
| US20160067190A1 (en) | 2013-04-30 | 2016-03-10 | The Children's Medical Center Corporation | Injectable nano-network gels for diabetes treatment |
| US10987039B2 (en) | 2014-12-03 | 2021-04-27 | Stmicroelectronics S.R.L. | Microneedle array device and method of making |
| TN2017000439A1 (en) | 2015-04-21 | 2019-04-12 | Univ North Carolina State | Glucose-responsive insulin delivery system using hyoxia-sensitive nanocomposites |
| WO2016172554A1 (en) | 2015-04-23 | 2016-10-27 | Carnegie Mellon University | Biosensor tattoos and uses therefor for biomarker monitoring |
| CN110167537A (zh) | 2016-11-07 | 2019-08-23 | 北卡罗来纳州立大学 | 用于增强葡萄糖反应性胰岛素的递送的装有双敏感囊泡的贴剂 |
| CN110198730B (zh) | 2016-12-05 | 2023-10-03 | 北卡罗莱纳州立大学 | H2o2响应性纳米粒子及其用途 |
| DK3548135T3 (da) * | 2016-12-05 | 2021-11-22 | Univ North Carolina State | Kerne-skal-mikronålsindretninger og anvendelser deraf |
-
2017
- 2017-12-05 DK DK17879565.4T patent/DK3548135T3/da active
- 2017-12-05 JP JP2019529985A patent/JP7232526B2/ja active Active
- 2017-12-05 WO PCT/US2017/064723 patent/WO2018106696A1/en not_active Ceased
- 2017-12-05 EP EP17879565.4A patent/EP3548135B1/en not_active Not-in-force
- 2017-12-05 EP EP20205415.1A patent/EP3799865B1/en not_active Not-in-force
- 2017-12-05 CN CN201780081305.1A patent/CN110167624B/zh not_active Expired - Fee Related
- 2017-12-05 US US16/466,775 patent/US11697007B2/en active Active
- 2017-12-05 CA CA3045882A patent/CA3045882A1/en not_active Abandoned
-
2023
- 2023-05-23 US US18/321,936 patent/US20230364402A1/en active Pending
Also Published As
| Publication number | Publication date |
|---|---|
| EP3548135A1 (en) | 2019-10-09 |
| EP3799865A1 (en) | 2021-04-07 |
| EP3548135A4 (en) | 2020-07-29 |
| CN110167624B (zh) | 2021-11-19 |
| WO2018106696A1 (en) | 2018-06-14 |
| EP3548135B1 (en) | 2021-10-13 |
| CA3045882A1 (en) | 2018-06-14 |
| US11697007B2 (en) | 2023-07-11 |
| JP2020512283A (ja) | 2020-04-23 |
| JP7232526B2 (ja) | 2023-03-03 |
| US20230364402A1 (en) | 2023-11-16 |
| EP3799865B1 (en) | 2022-06-15 |
| US20190351206A1 (en) | 2019-11-21 |
| CN110167624A (zh) | 2019-08-23 |
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