DK3528830T3 - Polymyxin-alginat-oligomer-konjugater - Google Patents

Polymyxin-alginat-oligomer-konjugater Download PDF

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Publication number
DK3528830T3
DK3528830T3 DK17791037.9T DK17791037T DK3528830T3 DK 3528830 T3 DK3528830 T3 DK 3528830T3 DK 17791037 T DK17791037 T DK 17791037T DK 3528830 T3 DK3528830 T3 DK 3528830T3
Authority
DK
Denmark
Prior art keywords
polymyxin
alginate oligomer
oligomer conjugates
conjugates
alginate
Prior art date
Application number
DK17791037.9T
Other languages
Danish (da)
English (en)
Inventor
Elaine Ferguson
David William Thomas
Philip Rye
Arne Dessen
Original Assignee
Algipharma As
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from GBGB1617860.0A external-priority patent/GB201617860D0/en
Priority claimed from GBGB1714710.9A external-priority patent/GB201714710D0/en
Application filed by Algipharma As filed Critical Algipharma As
Application granted granted Critical
Publication of DK3528830T3 publication Critical patent/DK3528830T3/da

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/04Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
    • A61K38/12Cyclic peptides, e.g. bacitracins; Polymyxins; Gramicidins S, C; Tyrocidins A, B or C
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/50Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
    • A61K47/51Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
    • A61K47/56Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic macromolecular compound, e.g. an oligomeric, polymeric or dendrimeric molecule
    • A61K47/61Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic macromolecular compound, e.g. an oligomeric, polymeric or dendrimeric molecule the organic macromolecular compound being a polysaccharide or a derivative thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00Drugs for disorders of the respiratory system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04Antibacterial agents
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02ATECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A50/00TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
    • Y02A50/30Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Epidemiology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Immunology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Pulmonology (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Medicinal Preparation (AREA)
DK17791037.9T 2016-10-21 2017-10-20 Polymyxin-alginat-oligomer-konjugater DK3528830T3 (da)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
GBGB1617860.0A GB201617860D0 (en) 2016-10-21 2016-10-21 Polymyxin-alginate oligomer conjugates
GBGB1714710.9A GB201714710D0 (en) 2017-09-13 2017-09-13 Polymyxin-alginate oligomer conjugates
PCT/EP2017/076927 WO2018073449A1 (en) 2016-10-21 2017-10-20 Polymyxin-alginate oligomer conjugates

Publications (1)

Publication Number Publication Date
DK3528830T3 true DK3528830T3 (da) 2022-12-19

Family

ID=60186268

Family Applications (1)

Application Number Title Priority Date Filing Date
DK17791037.9T DK3528830T3 (da) 2016-10-21 2017-10-20 Polymyxin-alginat-oligomer-konjugater

Country Status (13)

Country Link
US (1) US20190328833A1 (enExample)
EP (1) EP3528830B1 (enExample)
JP (1) JP2020503253A (enExample)
KR (1) KR20190072579A (enExample)
CN (1) CN109843315A (enExample)
AU (1) AU2017345295A1 (enExample)
BR (1) BR112019007927A2 (enExample)
CA (1) CA3040795A1 (enExample)
DK (1) DK3528830T3 (enExample)
ES (1) ES2933983T3 (enExample)
FI (1) FI3528830T3 (enExample)
RU (1) RU2019109719A (enExample)
WO (1) WO2018073449A1 (enExample)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN115003311B (zh) * 2019-12-14 2024-04-19 乔杜里·马努 降低多器官毒性的多元药物制剂
US20230141981A1 (en) * 2020-01-21 2023-05-11 Shanghai Micurx Pharmaceuticals Co., Ltd Novel compounds and composition for targeted therapy of kidney-associated cancers
US12037631B2 (en) * 2020-10-06 2024-07-16 City University Of Hong Kong System and method for detecting a target enzyme
CN113081956A (zh) * 2021-04-12 2021-07-09 青岛大学附属医院 一种氧化海藻酸钠改性的那他霉素滴眼液及其制备方法
CN113069556B (zh) * 2021-04-12 2022-04-08 青岛大学附属医院 一种枝接那他霉素的氧化海藻酸纤维膜及其制备方法
US20240376155A1 (en) * 2021-07-21 2024-11-14 Shanghai Micurx Pharmaceutical Co., Ltd. Novel compounds and compositions for targeted therapy of renal cancers
EP4373836A4 (en) * 2021-07-21 2025-10-22 Shanghai Micurx Pharmaceutical Co Ltd COMPOUNDS AND COMPOSITIONS FOR TARGETED THERAPY OF KIDNEY DISEASES
CN114009731B (zh) * 2021-11-05 2024-01-02 恒枫食品科技有限公司 一种茶风味基料及其制备方法、应用
CN114752535A (zh) * 2022-05-16 2022-07-15 北京昊峰节能环保科技有限公司 一种总石油烃污染地下水生物修复剂及其制备方法与应用

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB976301A (en) * 1960-10-27 1964-11-25 Calmic Ltd Preparation and use of alginates
US5177059A (en) * 1989-11-15 1993-01-05 Sandoz Ltd. Polymyxin B conjugates
IL96326A (en) * 1989-11-15 1995-07-31 Sandoz Ag Polymyxin conjugates, their preparation and pharmaceutical preparations containing them
GB2270920B (en) * 1992-09-25 1997-04-02 Univ Keele Alginate-bioactive agent conjugates
US6011008A (en) * 1997-01-08 2000-01-04 Yissum Research Developement Company Of The Hebrew University Of Jerusalem Conjugates of biologically active substances
PT2268142T (pt) * 2007-11-27 2017-06-02 Algipharma As Utilização de oligómeros alginados no combate aos biofilmes
RU2586253C2 (ru) * 2009-06-03 2016-06-10 АльгиФарма АС Обработка акинетобактерий альгинатными олигомерами и антибиотиками

Also Published As

Publication number Publication date
KR20190072579A (ko) 2019-06-25
RU2019109719A (ru) 2020-11-24
WO2018073449A1 (en) 2018-04-26
CA3040795A1 (en) 2018-04-26
FI3528830T3 (fi) 2023-01-13
EP3528830B1 (en) 2022-10-05
EP3528830A1 (en) 2019-08-28
RU2019109719A3 (enExample) 2021-02-20
US20190328833A1 (en) 2019-10-31
BR112019007927A2 (pt) 2019-07-02
CN109843315A (zh) 2019-06-04
JP2020503253A (ja) 2020-01-30
AU2017345295A1 (en) 2019-05-02
ES2933983T3 (es) 2023-02-15

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