DK3528830T3 - Polymyxin-alginat-oligomer-konjugater - Google Patents

Polymyxin-alginat-oligomer-konjugater Download PDF

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Publication number
DK3528830T3
DK3528830T3 DK17791037.9T DK17791037T DK3528830T3 DK 3528830 T3 DK3528830 T3 DK 3528830T3 DK 17791037 T DK17791037 T DK 17791037T DK 3528830 T3 DK3528830 T3 DK 3528830T3
Authority
DK
Denmark
Prior art keywords
polymyxin
alginate oligomer
oligomer conjugates
conjugates
alginate
Prior art date
Application number
DK17791037.9T
Other languages
English (en)
Inventor
Elaine Ferguson
David William Thomas
Philip Rye
Arne Dessen
Original Assignee
Algipharma As
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from GBGB1617860.0A external-priority patent/GB201617860D0/en
Priority claimed from GBGB1714710.9A external-priority patent/GB201714710D0/en
Application filed by Algipharma As filed Critical Algipharma As
Application granted granted Critical
Publication of DK3528830T3 publication Critical patent/DK3528830T3/da

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/04Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
    • A61K38/12Cyclic peptides, e.g. bacitracins; Polymyxins; Gramicidins S, C; Tyrocidins A, B or C
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/50Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
    • A61K47/51Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
    • A61K47/56Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic macromolecular compound, e.g. an oligomeric, polymeric or dendrimeric molecule
    • A61K47/61Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic macromolecular compound, e.g. an oligomeric, polymeric or dendrimeric molecule the organic macromolecular compound being a polysaccharide or a derivative thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00Drugs for disorders of the respiratory system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04Antibacterial agents
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02ATECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A50/00TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
    • Y02A50/30Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Epidemiology (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Immunology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Pulmonology (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicinal Preparation (AREA)
  • Peptides Or Proteins (AREA)
DK17791037.9T 2016-10-21 2017-10-20 Polymyxin-alginat-oligomer-konjugater DK3528830T3 (da)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
GBGB1617860.0A GB201617860D0 (en) 2016-10-21 2016-10-21 Polymyxin-alginate oligomer conjugates
GBGB1714710.9A GB201714710D0 (en) 2017-09-13 2017-09-13 Polymyxin-alginate oligomer conjugates
PCT/EP2017/076927 WO2018073449A1 (en) 2016-10-21 2017-10-20 Polymyxin-alginate oligomer conjugates

Publications (1)

Publication Number Publication Date
DK3528830T3 true DK3528830T3 (da) 2022-12-19

Family

ID=60186268

Family Applications (1)

Application Number Title Priority Date Filing Date
DK17791037.9T DK3528830T3 (da) 2016-10-21 2017-10-20 Polymyxin-alginat-oligomer-konjugater

Country Status (13)

Country Link
US (1) US20190328833A1 (da)
EP (1) EP3528830B1 (da)
JP (1) JP2020503253A (da)
KR (1) KR20190072579A (da)
CN (1) CN109843315A (da)
AU (1) AU2017345295A1 (da)
BR (1) BR112019007927A2 (da)
CA (1) CA3040795A1 (da)
DK (1) DK3528830T3 (da)
ES (1) ES2933983T3 (da)
FI (1) FI3528830T3 (da)
RU (1) RU2019109719A (da)
WO (1) WO2018073449A1 (da)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20230104323A1 (en) * 2019-12-14 2023-04-06 Manu Chaudhary Formulations of polybasic drugs to reduce multi-organ toxicity
US20230141981A1 (en) * 2020-01-21 2023-05-11 Shanghai Micurx Pharmaceuticals Co., Ltd Novel compounds and composition for targeted therapy of kidney-associated cancers
US12037631B2 (en) * 2020-10-06 2024-07-16 City University Of Hong Kong System and method for detecting a target enzyme
CN113069556B (zh) * 2021-04-12 2022-04-08 青岛大学附属医院 一种枝接那他霉素的氧化海藻酸纤维膜及其制备方法
CN113081956A (zh) * 2021-04-12 2021-07-09 青岛大学附属医院 一种氧化海藻酸钠改性的那他霉素滴眼液及其制备方法
CN117642419A (zh) * 2021-07-21 2024-03-01 上海盟科药业股份有限公司 用于肾脏疾病靶向治疗的化合物和组合物
WO2023001224A1 (en) * 2021-07-21 2023-01-26 Shanghai Micurx Pharmaceutical Co., Ltd. Novel compounds and compositions for targeted therapy of renal cancers
CN114009731B (zh) * 2021-11-05 2024-01-02 恒枫食品科技有限公司 一种茶风味基料及其制备方法、应用
CN114752535A (zh) * 2022-05-16 2022-07-15 北京昊峰节能环保科技有限公司 一种总石油烃污染地下水生物修复剂及其制备方法与应用

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB976301A (en) * 1960-10-27 1964-11-25 Calmic Ltd Preparation and use of alginates
US5177059A (en) * 1989-11-15 1993-01-05 Sandoz Ltd. Polymyxin B conjugates
NZ236050A (en) * 1989-11-15 1993-04-28 Sandoz Ltd Water soluble conjugate of a polymyxin and a carrier
GB2270920B (en) * 1992-09-25 1997-04-02 Univ Keele Alginate-bioactive agent conjugates
US6011008A (en) * 1997-01-08 2000-01-04 Yissum Research Developement Company Of The Hebrew University Of Jerusalem Conjugates of biologically active substances
JP5639475B2 (ja) * 2007-11-27 2014-12-10 アルギファルマ アイピーアール エーエス バイオフィルムと闘う際のアルギネートオリゴマーの使用
CA2764195C (en) * 2009-06-03 2017-09-26 Algipharma As Treatment of acinetobacter with alginate oligomers and antibiotics

Also Published As

Publication number Publication date
JP2020503253A (ja) 2020-01-30
EP3528830B1 (en) 2022-10-05
RU2019109719A (ru) 2020-11-24
EP3528830A1 (en) 2019-08-28
US20190328833A1 (en) 2019-10-31
KR20190072579A (ko) 2019-06-25
CN109843315A (zh) 2019-06-04
RU2019109719A3 (da) 2021-02-20
WO2018073449A1 (en) 2018-04-26
FI3528830T3 (fi) 2023-01-13
BR112019007927A2 (pt) 2019-07-02
AU2017345295A1 (en) 2019-05-02
CA3040795A1 (en) 2018-04-26
ES2933983T3 (es) 2023-02-15

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