DK3528829T3 - Bacitracin-alginat-oligomer-konjugater - Google Patents

Bacitracin-alginat-oligomer-konjugater Download PDF

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Publication number
DK3528829T3
DK3528829T3 DK17787188.6T DK17787188T DK3528829T3 DK 3528829 T3 DK3528829 T3 DK 3528829T3 DK 17787188 T DK17787188 T DK 17787188T DK 3528829 T3 DK3528829 T3 DK 3528829T3
Authority
DK
Denmark
Prior art keywords
bacitracin
conjugates
alginate
oligomer
Prior art date
Application number
DK17787188.6T
Other languages
Danish (da)
English (en)
Inventor
Elaine Ferguson
David William Thomas
Philip Rye
Arne Dessen
Original Assignee
Algipharma As
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Algipharma As filed Critical Algipharma As
Application granted granted Critical
Publication of DK3528829T3 publication Critical patent/DK3528829T3/da

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Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/04Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
    • A61K38/12Cyclic peptides, e.g. bacitracins; Polymyxins; Gramicidins S, C; Tyrocidins A, B or C
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/26Carbohydrates, e.g. sugar alcohols, amino sugars, nucleic acids, mono-, di- or oligo-saccharides; Derivatives thereof, e.g. polysorbates, sorbitan fatty acid esters or glycyrrhizin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/36Polysaccharides; Derivatives thereof, e.g. gums, starch, alginate, dextrin, hyaluronic acid, chitosan, inulin, agar or pectin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/50Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
    • A61K47/51Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
    • A61K47/56Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic macromolecular compound, e.g. an oligomeric, polymeric or dendrimeric molecule
    • A61K47/61Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic macromolecular compound, e.g. an oligomeric, polymeric or dendrimeric molecule the organic macromolecular compound being a polysaccharide or a derivative thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04Antibacterial agents
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K7/00Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
    • C07K7/50Cyclic peptides containing at least one abnormal peptide link
    • C07K7/54Cyclic peptides containing at least one abnormal peptide link with at least one abnormal peptide link in the ring
    • C07K7/56Cyclic peptides containing at least one abnormal peptide link with at least one abnormal peptide link in the ring the cyclisation not occurring through 2,4-diamino-butanoic acid
    • C07K7/58Bacitracins; Related peptides
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02ATECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A50/00TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
    • Y02A50/30Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Organic Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Immunology (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Inorganic Chemistry (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Peptides Or Proteins (AREA)
  • Materials For Medical Uses (AREA)
DK17787188.6T 2016-10-21 2017-10-20 Bacitracin-alginat-oligomer-konjugater DK3528829T3 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GB1617862.6A GB2555391B (en) 2016-10-21 2016-10-21 Bacitracin-alginate oligomer conjugates
PCT/EP2017/076926 WO2018073448A1 (en) 2016-10-21 2017-10-20 Bacitracin-alginate oligomer conjugates

Publications (1)

Publication Number Publication Date
DK3528829T3 true DK3528829T3 (da) 2022-05-30

Family

ID=57738026

Family Applications (1)

Application Number Title Priority Date Filing Date
DK17787188.6T DK3528829T3 (da) 2016-10-21 2017-10-20 Bacitracin-alginat-oligomer-konjugater

Country Status (16)

Country Link
US (1) US20230139922A1 (enExample)
EP (1) EP3528829B1 (enExample)
JP (1) JP7191014B2 (enExample)
KR (1) KR20190070946A (enExample)
CN (1) CN109862904A (enExample)
AU (1) AU2017345294A1 (enExample)
BR (1) BR112019007928A2 (enExample)
CA (1) CA3040796A1 (enExample)
DK (1) DK3528829T3 (enExample)
ES (1) ES2914784T3 (enExample)
GB (1) GB2555391B (enExample)
PL (1) PL3528829T3 (enExample)
PT (1) PT3528829T (enExample)
RU (1) RU2766345C2 (enExample)
SI (1) SI3528829T1 (enExample)
WO (1) WO2018073448A1 (enExample)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN110484473B (zh) * 2019-08-31 2022-08-19 暨南大学 一种促进鹤羽田戴尔福特菌在植物根际定殖的方法
CN111057131A (zh) * 2019-12-13 2020-04-24 上海市食品药品检验所 一种杆菌肽及其组分的分析方法
CN111420024B (zh) * 2020-04-07 2023-10-03 中国科学院深圳先进技术研究院 杆菌酞a在制备预防和治疗冠状病毒的药物中的应用
CN112812150A (zh) * 2021-01-29 2021-05-18 深圳海创生物科技有限公司 一种活性环肽、活性环肽组合物及其在制备具有抗氧化或抗炎作用的产品中的应用
CN113413490B (zh) * 2021-05-14 2022-05-27 哈尔滨医科大学 一种超声响应性复合水凝胶及其制备方法和应用
CN117679350B (zh) * 2023-12-13 2024-06-07 诺德溯源(广州)生物科技有限公司 一种淡化痘印和抚平痘坑的愈创木组合物及其应用

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1433593A (en) * 1972-06-09 1976-04-28 Royal College Of Surgeons Conjugates
GB2270920B (en) * 1992-09-25 1997-04-02 Univ Keele Alginate-bioactive agent conjugates
US6248360B1 (en) * 2000-06-21 2001-06-19 International Health Management Associates, Inc. Complexes to improve oral absorption of poorly absorbable antibiotics
PT2268142T (pt) * 2007-11-27 2017-06-02 Algipharma As Utilização de oligómeros alginados no combate aos biofilmes
EP2161020A1 (en) * 2008-09-09 2010-03-10 Koninklijke Philips Electronics N.V. Chelating amphiphilic polymers
RU2586253C2 (ru) * 2009-06-03 2016-06-10 АльгиФарма АС Обработка акинетобактерий альгинатными олигомерами и антибиотиками
JP6336902B2 (ja) * 2011-06-22 2018-06-06 ビョーメ バイオサイエンシズ ピーブイティー.リミテッド コンジュゲートベースの抗真菌性および抗菌性プロドラッグ
WO2016081820A1 (en) * 2014-11-20 2016-05-26 University Of Southern California Use of alginate formulation for intraincisional drug delivery

Also Published As

Publication number Publication date
WO2018073448A1 (en) 2018-04-26
KR20190070946A (ko) 2019-06-21
ES2914784T3 (es) 2022-06-16
CN109862904A (zh) 2019-06-07
EP3528829B1 (en) 2022-03-02
GB2555391B (en) 2019-06-26
RU2019109728A3 (enExample) 2021-02-16
GB201617862D0 (en) 2016-12-07
BR112019007928A2 (pt) 2019-07-02
JP7191014B2 (ja) 2022-12-16
AU2017345294A1 (en) 2019-05-02
RU2766345C2 (ru) 2022-03-15
CA3040796A1 (en) 2018-04-26
SI3528829T1 (sl) 2022-07-29
GB2555391A (en) 2018-05-02
US20230139922A1 (en) 2023-05-04
RU2019109728A (ru) 2020-11-23
PT3528829T (pt) 2022-06-02
PL3528829T3 (pl) 2022-09-19
EP3528829A1 (en) 2019-08-28
JP2019535669A (ja) 2019-12-12

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