DK3515406T3 - Intrakamerale depoter til lægemiddeladministration - Google Patents
Intrakamerale depoter til lægemiddeladministration Download PDFInfo
- Publication number
- DK3515406T3 DK3515406T3 DK17780606.4T DK17780606T DK3515406T3 DK 3515406 T3 DK3515406 T3 DK 3515406T3 DK 17780606 T DK17780606 T DK 17780606T DK 3515406 T3 DK3515406 T3 DK 3515406T3
- Authority
- DK
- Denmark
- Prior art keywords
- intracameral
- depots
- drug administration
- administration
- drug
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0048—Eye, e.g. artificial tears
- A61K9/0051—Ocular inserts or implants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F9/00—Methods or devices for treatment of the eyes; Devices for putting in contact-lenses; Devices to correct squinting; Apparatus to guide the blind; Protective devices for the eyes, carried on the body or in the hand
- A61F9/0008—Introducing ophthalmic products into the ocular cavity or retaining products therein
- A61F9/0017—Introducing ophthalmic products into the ocular cavity or retaining products therein implantable in, or in contact with, the eye, e.g. ocular inserts
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F9/00—Methods or devices for treatment of the eyes; Devices for putting in contact-lenses; Devices to correct squinting; Apparatus to guide the blind; Protective devices for the eyes, carried on the body or in the hand
- A61F9/007—Methods or devices for eye surgery
- A61F9/00781—Apparatus for modifying intraocular pressure, e.g. for glaucoma treatment
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/557—Eicosanoids, e.g. leukotrienes or prostaglandins
- A61K31/5575—Eicosanoids, e.g. leukotrienes or prostaglandins having a cyclopentane, e.g. prostaglandin E2, prostaglandin F2-alpha
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
- A61K47/10—Alcohols; Phenols; Salts thereof, e.g. glycerol; Polyethylene glycols [PEG]; Poloxamers; PEG/POE alkyl ethers
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
- A61K9/1605—Excipients; Inactive ingredients
- A61K9/1629—Organic macromolecular compounds
- A61K9/1641—Organic macromolecular compounds obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyethylene glycol, poloxamers
- A61K9/1647—Polyesters, e.g. poly(lactide-co-glycolide)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
- A61P27/06—Antiglaucoma agents or miotics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
- A61P27/12—Ophthalmic agents for cataracts
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/38—Heterocyclic compounds having sulfur as a ring hetero atom
- A61K31/382—Heterocyclic compounds having sulfur as a ring hetero atom having six-membered rings, e.g. thioxanthenes
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
- A61K47/34—Macromolecular compounds obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyesters, polyamino acids, polysiloxanes, polyphosphazines, copolymers of polyalkylene glycol or poloxamers
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0087—Galenical forms not covered by A61K9/02 - A61K9/7023
- A61K9/0092—Hollow drug-filled fibres, tubes of the core-shell type, coated fibres, coated rods, microtubules or nanotubes
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Engineering & Computer Science (AREA)
- Ophthalmology & Optometry (AREA)
- Epidemiology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- Biomedical Technology (AREA)
- Heart & Thoracic Surgery (AREA)
- Vascular Medicine (AREA)
- Oil, Petroleum & Natural Gas (AREA)
- Surgery (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Inorganic Chemistry (AREA)
- Nanotechnology (AREA)
- Medicinal Preparation (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201662398985P | 2016-09-23 | 2016-09-23 | |
| PCT/US2017/053271 WO2018058048A1 (en) | 2016-09-23 | 2017-09-25 | Intracameral drug delivery depots |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| DK3515406T3 true DK3515406T3 (da) | 2024-10-14 |
Family
ID=60022215
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DK17780606.4T DK3515406T3 (da) | 2016-09-23 | 2017-09-25 | Intrakamerale depoter til lægemiddeladministration |
Country Status (10)
| Country | Link |
|---|---|
| US (3) | US12171869B2 (enExample) |
| EP (2) | EP3515406B1 (enExample) |
| JP (2) | JP7430529B2 (enExample) |
| KR (3) | KR102814241B1 (enExample) |
| CN (1) | CN109982683A (enExample) |
| AU (1) | AU2017331444B2 (enExample) |
| DK (1) | DK3515406T3 (enExample) |
| ES (1) | ES2989941T3 (enExample) |
| IL (1) | IL265421B2 (enExample) |
| WO (1) | WO2018058048A1 (enExample) |
Families Citing this family (19)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2017062770A1 (en) | 2015-10-08 | 2017-04-13 | Silverberg Noah | Punctal plug and bioadhesives |
| AU2017331444B2 (en) * | 2016-09-23 | 2023-08-17 | Incept, Llc | Intracameral drug delivery depots |
| CA3133172A1 (en) * | 2019-03-13 | 2020-09-17 | Susmita Bose | Enzyme-degradable hydrogel for delivery of a payload |
| CN113766912A (zh) * | 2019-04-25 | 2021-12-07 | 视觉治疗股份有限公司 | 用于递送麻醉剂的小管内水凝胶插入物 |
| US20200337989A1 (en) * | 2019-04-25 | 2020-10-29 | Ocular Therapeutix, Inc. | Ocular hydrogel tyrosine kinase inhibitor implants |
| WO2020219892A1 (en) * | 2019-04-25 | 2020-10-29 | Ocular Therapeutix, Inc. | Hydrogel implants for lowering intraocular pressure |
| WO2021158968A1 (en) * | 2020-02-06 | 2021-08-12 | Ocular Therapeutix, Inc. | Compositions and methods for treating ocular diseases |
| PT3884929T (pt) | 2020-03-25 | 2023-08-09 | Ocular Therapeutix Inc | Implante ocular contendo um inibidor da tirosina cinase |
| CA3177005A1 (en) | 2020-04-27 | 2021-11-04 | Michael Goldstein | Methods of treating allergic conjunctivitis |
| BR112023000669A2 (pt) * | 2020-07-16 | 2023-04-25 | Ocular Therapeutix Inc | Inserto ocular contendo um glicocorticoide |
| KR102893953B1 (ko) * | 2020-09-24 | 2025-12-02 | 오큘라 테라퓨틱스, 인코포레이티드 | 하이드로겔 및 사이클로스포린을 포함하는 지속 방출 생분해성 소관내 삽입체 |
| JP2023542939A (ja) * | 2020-09-24 | 2023-10-12 | オキュラ セラピューティクス，インコーポレイテッド | ヒドロゲル及び活性薬剤を含む徐放性生分解性小管内挿入物 |
| EP4346720A4 (en) * | 2021-05-28 | 2025-01-01 | Sight Sciences, Inc. | INTRAOCULAR DEVICES, SYSTEMS AND METHODS |
| CN114748436B (zh) * | 2022-05-30 | 2023-05-16 | 迪沙药业集团有限公司 | 一种硝苯地平组合物及其制备方法 |
| JP2025526731A (ja) * | 2022-08-12 | 2025-08-15 | オキュラ セラピューティクス，インコーポレイテッド | 持続的薬物送達のためのオルガノゲル、その調製及び使用の方法 |
| CN115337453A (zh) * | 2022-08-15 | 2022-11-15 | 珠海肤原生物科技有限公司 | 一种载有2-氧杂环庚烷酮的均聚物微球的医用无菌胶原蛋白产品的制备 |
| WO2024191453A1 (en) * | 2023-03-10 | 2024-09-19 | Clearstream Technologies Limited | Radiation spacer hydrogels, methods of forming, and methods of use |
| AU2024251447A1 (en) | 2023-04-11 | 2025-08-21 | Ocular Therapeutix, Inc. | Ocular implant comprising axitinib polymorph iv |
| WO2025255203A1 (en) * | 2024-06-06 | 2025-12-11 | Ocular Therapeutix, Inc. | Compositions and methods for treating ocular diseases |
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| DE2437629C3 (de) | 1974-08-05 | 1978-09-21 | Basf Ag, 6700 Ludwigshafen | Verfahren zur Herstellung von unlöslichen in Wasser nur wenig quellbaren Polymerisaten von N-Vinyllactamen |
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| ES2930433T3 (es) * | 2013-03-05 | 2022-12-12 | Univ Pittsburgh Commonwealth Sys Higher Education | Hidrogel termosensible que contiene micropartículas de polímero para la administración ocular no invasiva de fármaco |
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| AU2017331444B2 (en) | 2016-09-23 | 2023-08-17 | Incept, Llc | Intracameral drug delivery depots |
-
2017
- 2017-09-25 AU AU2017331444A patent/AU2017331444B2/en active Active
- 2017-09-25 DK DK17780606.4T patent/DK3515406T3/da active
- 2017-09-25 KR KR1020247011510A patent/KR102814241B1/ko active Active
- 2017-09-25 KR KR1020237011914A patent/KR20230053707A/ko not_active Ceased
- 2017-09-25 US US15/714,633 patent/US12171869B2/en active Active
- 2017-09-25 WO PCT/US2017/053271 patent/WO2018058048A1/en not_active Ceased
- 2017-09-25 CN CN201780072266.9A patent/CN109982683A/zh active Pending
- 2017-09-25 JP JP2019515849A patent/JP7430529B2/ja active Active
- 2017-09-25 IL IL265421A patent/IL265421B2/en unknown
- 2017-09-25 EP EP17780606.4A patent/EP3515406B1/en active Active
- 2017-09-25 EP EP23154758.9A patent/EP4197527A1/en active Pending
- 2017-09-25 KR KR1020197011614A patent/KR102520771B1/ko active Active
- 2017-09-25 ES ES17780606T patent/ES2989941T3/es active Active
-
2022
- 2022-04-08 JP JP2022064398A patent/JP7486539B2/ja active Active
- 2022-08-18 US US17/890,997 patent/US20220401356A1/en not_active Abandoned
-
2024
- 2024-11-11 US US18/943,498 patent/US20250144012A1/en active Pending
Also Published As
| Publication number | Publication date |
|---|---|
| IL265421A (en) | 2019-05-30 |
| KR102520771B1 (ko) | 2023-04-12 |
| EP3515406A1 (en) | 2019-07-31 |
| JP2022091998A (ja) | 2022-06-21 |
| CN109982683A (zh) | 2019-07-05 |
| IL265421B1 (en) | 2023-12-01 |
| AU2017331444B2 (en) | 2023-08-17 |
| EP4197527A1 (en) | 2023-06-21 |
| AU2017331444A1 (en) | 2019-04-18 |
| KR20240051303A (ko) | 2024-04-19 |
| WO2018058048A1 (en) | 2018-03-29 |
| JP7430529B2 (ja) | 2024-02-13 |
| KR20190057353A (ko) | 2019-05-28 |
| IL265421B2 (en) | 2024-04-01 |
| KR20230053707A (ko) | 2023-04-21 |
| US20220401356A1 (en) | 2022-12-22 |
| JP2019529455A (ja) | 2019-10-17 |
| US20250144012A1 (en) | 2025-05-08 |
| ES2989941T3 (es) | 2024-11-28 |
| JP7486539B2 (ja) | 2024-05-17 |
| US12171869B2 (en) | 2024-12-24 |
| EP3515406B1 (en) | 2024-07-24 |
| BR112019005594A2 (pt) | 2019-08-13 |
| KR102814241B1 (ko) | 2025-05-29 |
| CA3038075A1 (en) | 2018-03-29 |
| US20180085307A1 (en) | 2018-03-29 |
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