DK3507299T3 - Fremgangsmåde til genvinding af in-situ-opløsningsmiddel til fastfasepeptidsyntese ved forhøjede temperaturer - Google Patents

Fremgangsmåde til genvinding af in-situ-opløsningsmiddel til fastfasepeptidsyntese ved forhøjede temperaturer Download PDF

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Publication number
DK3507299T3
DK3507299T3 DK17847113.2T DK17847113T DK3507299T3 DK 3507299 T3 DK3507299 T3 DK 3507299T3 DK 17847113 T DK17847113 T DK 17847113T DK 3507299 T3 DK3507299 T3 DK 3507299T3
Authority
DK
Denmark
Prior art keywords
procedure
solid
elevated temperatures
peptide synthesis
phase peptide
Prior art date
Application number
DK17847113.2T
Other languages
Danish (da)
English (en)
Inventor
Jonathan M Collins
Original Assignee
Cem Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from PCT/US2016/058181 external-priority patent/WO2017070512A1/en
Priority claimed from US15/490,090 external-priority patent/US10239914B2/en
Application filed by Cem Corp filed Critical Cem Corp
Application granted granted Critical
Publication of DK3507299T3 publication Critical patent/DK3507299T3/da

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Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K1/00General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
    • C07K1/04General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length on carriers
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K1/00General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
    • C07K1/04General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length on carriers
    • C07K1/045General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length on carriers using devices to improve synthesis, e.g. reactors, special vessels
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K1/00General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
    • C07K1/04General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length on carriers
    • C07K1/047Simultaneous synthesis of different peptide species; Peptide libraries
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02PCLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00Technologies relating to chemical industry
    • Y02P20/50Improvements relating to the production of bulk chemicals
    • Y02P20/55Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Analytical Chemistry (AREA)
  • Peptides Or Proteins (AREA)
DK17847113.2T 2016-09-03 2017-04-19 Fremgangsmåde til genvinding af in-situ-opløsningsmiddel til fastfasepeptidsyntese ved forhøjede temperaturer DK3507299T3 (da)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US201662383397P 2016-09-03 2016-09-03
PCT/US2016/058181 WO2017070512A1 (en) 2015-10-23 2016-10-21 Improvements in solid phase peptide synthesis
US15/299,931 US10125163B2 (en) 2015-10-23 2016-10-21 Solid phase peptide synthesis
US15/490,090 US10239914B2 (en) 2015-10-23 2017-04-18 In-situ solvent recycling process for solid phase peptide synthesis at elevated temperatures
PCT/US2017/028254 WO2018044356A1 (en) 2016-09-03 2017-04-19 In-situ solvent recycling process for solid phase peptide synthesis at elevated temperatures

Publications (1)

Publication Number Publication Date
DK3507299T3 true DK3507299T3 (da) 2022-09-05

Family

ID=61301481

Family Applications (1)

Application Number Title Priority Date Filing Date
DK17847113.2T DK3507299T3 (da) 2016-09-03 2017-04-19 Fremgangsmåde til genvinding af in-situ-opløsningsmiddel til fastfasepeptidsyntese ved forhøjede temperaturer

Country Status (6)

Country Link
EP (1) EP3507299B1 (enExample)
JP (1) JP2019530659A (enExample)
CN (1) CN109715647A (enExample)
CA (1) CA3034810C (enExample)
DK (1) DK3507299T3 (enExample)
WO (1) WO2018044356A1 (enExample)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
USRE49961E1 (en) 2016-10-21 2024-05-07 Cem Corporation Solid phase peptide syntheses
EP4551587A1 (en) * 2022-09-16 2025-05-14 CEM Corporation Peptide synthesis processes

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20040238794A1 (en) * 2003-05-30 2004-12-02 Karandikar Prashant G. Microwave processing of composite bodies made by an infiltration route
US7393920B2 (en) * 2003-06-23 2008-07-01 Cem Corporation Microwave-assisted peptide synthesis
US7902488B2 (en) * 2003-06-23 2011-03-08 Cem Corporation Microwave-assisted peptide synthesis
WO2006026184A2 (en) * 2004-08-20 2006-03-09 Washington University Blood brain barrier permeation peptides
US8314208B2 (en) * 2006-02-10 2012-11-20 Cem Corporation Microwave enhanced N-fmoc deprotection in peptide synthesis
CA2808270A1 (en) * 2010-08-16 2012-02-23 Cem Corporation Water soluble solid phase peptide synthesis
US8906681B2 (en) * 2011-08-02 2014-12-09 The Scripps Research Institute Reliable stabilization of N-linked polypeptide native states with enhanced aromatic sequons located in polypeptide tight turns
EP2703073A1 (en) * 2012-08-31 2014-03-05 Biotage AB Apparatus and method for solid phase synthesis
US9169287B2 (en) * 2013-03-15 2015-10-27 Massachusetts Institute Of Technology Solid phase peptide synthesis processes and associated systems
EP3365352A4 (en) * 2015-10-23 2019-06-05 CEM Corporation IMPROVEMENTS OF SOLID PHASE PEPTIDE SYNTHESIS

Also Published As

Publication number Publication date
JP2019530659A (ja) 2019-10-24
CN109715647A (zh) 2019-05-03
EP3507299A4 (en) 2020-04-29
CA3034810A1 (en) 2018-03-08
WO2018044356A1 (en) 2018-03-08
EP3507299A1 (en) 2019-07-10
CA3034810C (en) 2023-09-05
EP3507299B1 (en) 2022-07-27

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