DK3501534T5 - Vaccinesammensætninger omfattende en muteret faktor h-bindende protein - Google Patents

Vaccinesammensætninger omfattende en muteret faktor h-bindende protein Download PDF

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Publication number
DK3501534T5
DK3501534T5 DK18209661.0T DK18209661T DK3501534T5 DK 3501534 T5 DK3501534 T5 DK 3501534T5 DK 18209661 T DK18209661 T DK 18209661T DK 3501534 T5 DK3501534 T5 DK 3501534T5
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DK
Denmark
Prior art keywords
binding protein
vaccine compositions
mutated factor
mutated
factor
Prior art date
Application number
DK18209661.0T
Other languages
Danish (da)
English (en)
Other versions
DK3501534T3 (da
Inventor
Rachel Exley
Christoph Tang
Susan M Lea
Original Assignee
Ip2Ipo Innovations Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ip2Ipo Innovations Ltd filed Critical Ip2Ipo Innovations Ltd
Publication of DK3501534T3 publication Critical patent/DK3501534T3/da
Application granted granted Critical
Publication of DK3501534T5 publication Critical patent/DK3501534T5/da

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Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K39/02Bacterial antigens
    • A61K39/095Neisseria
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/66Microorganisms or materials therefrom
    • A61K35/74Bacteria
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/16Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K39/02Bacterial antigens
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04Antibacterial agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12Antivirals
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • A61P37/02Immunomodulators
    • A61P37/04Immunostimulants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Immunology (AREA)
  • Epidemiology (AREA)
  • Microbiology (AREA)
  • Mycology (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Molecular Biology (AREA)
  • Virology (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
DK18209661.0T 2008-10-25 2009-10-26 Vaccinesammensætninger omfattende en muteret faktor h-bindende protein DK3501534T5 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GBGB0819633.9A GB0819633D0 (en) 2008-10-25 2008-10-25 Composition
EP09753188.3A EP2355845B1 (en) 2008-10-25 2009-10-26 Vaccine compositions comprising a mutated factor h binding protein

Publications (2)

Publication Number Publication Date
DK3501534T3 DK3501534T3 (da) 2024-02-05
DK3501534T5 true DK3501534T5 (da) 2024-09-02

Family

ID=40133849

Family Applications (1)

Application Number Title Priority Date Filing Date
DK18209661.0T DK3501534T5 (da) 2008-10-25 2009-10-26 Vaccinesammensætninger omfattende en muteret faktor h-bindende protein

Country Status (23)

Country Link
US (1) US20120052092A1 (OSRAM)
EP (2) EP3501534B1 (OSRAM)
JP (2) JP5676458B2 (OSRAM)
KR (3) KR20170000390A (OSRAM)
CN (2) CN102245202A (OSRAM)
AU (1) AU2009306114B2 (OSRAM)
BR (1) BRPI0919926A2 (OSRAM)
CA (1) CA2741619A1 (OSRAM)
CO (1) CO6382140A2 (OSRAM)
DK (1) DK3501534T5 (OSRAM)
ES (1) ES2970878T3 (OSRAM)
FI (1) FI3501534T3 (OSRAM)
GB (1) GB0819633D0 (OSRAM)
HR (1) HRP20240226T1 (OSRAM)
HU (1) HUE065348T2 (OSRAM)
LT (1) LT3501534T (OSRAM)
MX (1) MX2011004322A (OSRAM)
NZ (2) NZ592444A (OSRAM)
PL (1) PL3501534T3 (OSRAM)
PT (1) PT3501534T (OSRAM)
RU (1) RU2559528C2 (OSRAM)
SI (1) SI3501534T1 (OSRAM)
WO (1) WO2010046715A1 (OSRAM)

Families Citing this family (33)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DK1093517T3 (da) 1998-05-01 2008-06-23 Novartis Vaccines & Diagnostic Neisseria-meningitidis-antigener og præparater
NZ515935A (en) 1999-05-19 2004-01-30 Chiron S Combination Neisserial compositions and vaccines for the prevention of infections due to Neisseria bacteria such as meningococcal meningitis
EP2275553B1 (en) 1999-10-29 2015-05-13 Novartis Vaccines and Diagnostics S.r.l. Neisserial antigenic peptides
JP4763210B2 (ja) 2000-02-28 2011-08-31 ノバルティス ヴァクシンズ アンド ダイアグノスティクス エスアールエル ナイセリアのタンパク質の異種発現
GB0118249D0 (en) 2001-07-26 2001-09-19 Chiron Spa Histidine vaccines
GB0121591D0 (en) 2001-09-06 2001-10-24 Chiron Spa Hybrid and tandem expression of neisserial proteins
MXPA05003863A (es) 2002-10-11 2005-09-08 Chiron Srl Vacunas polipeptidicas para amplia proteccion contra lineas hipervirulentas de meningococos.
GB0227346D0 (en) 2002-11-22 2002-12-31 Chiron Spa 741
GB0408977D0 (en) 2004-04-22 2004-05-26 Chiron Srl Immunising against meningococcal serogroup Y using proteins
GB0524066D0 (en) 2005-11-25 2006-01-04 Chiron Srl 741 ii
NZ587382A (en) 2008-02-21 2012-01-12 Novartis Ag Meningococcal fhbp polypeptides
EP2265640B1 (en) 2008-03-10 2015-11-04 Children's Hospital & Research Center at Oakland Chimeric factor h binding proteins (fhbp) containing a heterologous b domain and methods of use
NZ595234A (en) 2009-03-24 2013-12-20 Novartis Ag Adjuvanting meningococcal factor h binding protein
WO2010127172A2 (en) 2009-04-30 2010-11-04 Children's Hospital & Research Center At Oakland Chimeric factor h binding proteins (fhbp) and methods of use
WO2011051893A1 (en) 2009-10-27 2011-05-05 Novartis Ag Modified meningococcal fhbp polypeptides
WO2011110634A1 (en) * 2010-03-10 2011-09-15 Glaxosmithkline Biologicals S.A. Vaccine composition
CN110845585A (zh) * 2010-03-30 2020-02-28 奥克兰儿童医院及研究中心 改性的h因子结合蛋白(fhbp)及其使用方法
EP2585106A1 (en) 2010-06-25 2013-05-01 Novartis AG Combinations of meningococcal factor h binding proteins
EP2809785B1 (en) 2012-02-02 2017-11-01 GlaxoSmithKline Biologicals SA Promoters for increased protein expression in meningococcus
WO2013186753A1 (en) 2012-06-14 2013-12-19 Novartis Ag Vaccines for serogroup x meningococcus
CA2875391A1 (en) 2012-07-27 2014-01-30 Institut National De La Sante Et De La Recherche Medicale Cd147 as receptor for pilus-mediated adhesion of meningococci to vascular endothelia
WO2014140562A1 (en) * 2013-03-14 2014-09-18 Isis Innovation Limited Immunogenic composition to neisseria
EP3027206A4 (en) 2013-08-02 2017-03-08 Children's Hospital & Research Center Oakland Non-naturally occurring factor h binding proteins (fhbp) and methods of use thereof
SI3110442T1 (sl) 2014-02-28 2021-01-29 Glaxosmithkline Biologicals S.A. Modificirani meningokokni fHbp polipeptidi
EP3172224B1 (en) 2014-07-23 2022-06-29 Children's Hospital & Research Center at Oakland Factor h binding protein variants and methods of use thereof
KR102709811B1 (ko) * 2014-08-20 2024-09-24 스티흐팅 산퀸 불드포르지닝 인자 h 강화 항체 및 그의 용도
GB201614687D0 (en) * 2016-08-31 2016-10-12 Univ Oxford Innovation Ltd fHbp scaffold
EP3607967A1 (en) 2018-08-09 2020-02-12 GlaxoSmithKline Biologicals S.A. Modified meningococcal fhbp polypeptides
WO2020124159A1 (en) 2018-12-21 2020-06-25 Griffith University Compositions, methods and uses for eliciting an immune response
WO2021007365A1 (en) * 2019-07-08 2021-01-14 Crapaud Bio, Inc. Methods of making and using lipooligosaccharide compositions and vaccines
BR112022000739A2 (pt) 2019-07-17 2022-04-12 Gemini Therapeutics Sub Inc Anticorpos de potencialização de fator h e usos dos mesmos
MX2023009728A (es) 2021-02-19 2023-08-30 Sanofi Pasteur Inc Vacuna recombinante meningococica b.
TW202423477A (zh) 2022-08-03 2024-06-16 美商賽諾菲巴斯德公司 針對腦膜炎奈瑟氏菌b的含佐劑免疫原性組成物

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4786592A (en) * 1986-06-18 1988-11-22 Scripps Clinic And Research Foundation Neisseria gonorrhoeae lectin useful as a vaccine and diagnostic marker and means for producing this lectin
US5476784A (en) * 1993-04-06 1995-12-19 Rice; Peter A. Gonococcal anti-idiotypic antibodies and methods and compositions using them
GB0220194D0 (en) * 2002-08-30 2002-10-09 Chiron Spa Improved vesicles
US20070253964A1 (en) * 2003-04-16 2007-11-01 Zlotnick Gary W Novel Immunogenic Compositions for the Prevention and Treatment of Meningococcal Disease
EP1855715B1 (en) * 2005-01-27 2013-03-13 Children's Hospital & Research Center at Oakland Gna1870-based vesicle vaccines for broad spectrum protection against diseases caused by neisseria meningitidis
GB0524066D0 (en) * 2005-11-25 2006-01-04 Chiron Srl 741 ii
US8039007B2 (en) * 2006-06-29 2011-10-18 J. Craig Venter Institute, Inc. Polypeptides from Neisseria meningitidis
EP3017828A1 (en) * 2009-08-27 2016-05-11 GlaxoSmithKline Biologicals SA Hybrid polypeptides including meningococcal fhbp sequences
CN110845585A (zh) * 2010-03-30 2020-02-28 奥克兰儿童医院及研究中心 改性的h因子结合蛋白(fhbp)及其使用方法

Also Published As

Publication number Publication date
CO6382140A2 (es) 2012-02-15
CN105412920A (zh) 2016-03-23
PT3501534T (pt) 2024-02-07
AU2009306114A1 (en) 2010-04-29
JP6076326B2 (ja) 2017-02-08
KR20190011836A (ko) 2019-02-07
DK3501534T3 (da) 2024-02-05
RU2011120706A (ru) 2012-11-27
SI3501534T1 (sl) 2024-03-29
EP2355845A1 (en) 2011-08-17
LT3501534T (lt) 2024-03-12
ES2970878T3 (es) 2024-05-31
KR20110092282A (ko) 2011-08-17
MX2011004322A (es) 2011-06-16
GB0819633D0 (en) 2008-12-03
KR20170000390A (ko) 2017-01-02
BRPI0919926A2 (pt) 2016-02-16
HUE065348T2 (hu) 2024-05-28
EP3501534B1 (en) 2023-11-29
NZ601538A (en) 2014-01-31
EP3501534A1 (en) 2019-06-26
JP2015063558A (ja) 2015-04-09
CA2741619A1 (en) 2010-04-29
NZ592444A (en) 2012-11-30
US20120052092A1 (en) 2012-03-01
JP5676458B2 (ja) 2015-02-25
WO2010046715A1 (en) 2010-04-29
RU2559528C2 (ru) 2015-08-10
AU2009306114B2 (en) 2015-10-01
EP2355845B1 (en) 2018-12-05
FI3501534T3 (fi) 2024-02-09
HRP20240226T1 (hr) 2024-05-10
CN102245202A (zh) 2011-11-16
JP2012506411A (ja) 2012-03-15
PL3501534T3 (pl) 2024-04-02

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