DK3446695T3 - Forbedret fremgangsmåde til fremstilling af en blød gelkapsel omfattende levedygtige probiotiske bakterier og en blød gelkapsel omfattende levedygtige probiotiske bakterier med en lang holdbarhed - Google Patents

Forbedret fremgangsmåde til fremstilling af en blød gelkapsel omfattende levedygtige probiotiske bakterier og en blød gelkapsel omfattende levedygtige probiotiske bakterier med en lang holdbarhed Download PDF

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Publication number
DK3446695T3
DK3446695T3 DK18194526.2T DK18194526T DK3446695T3 DK 3446695 T3 DK3446695 T3 DK 3446695T3 DK 18194526 T DK18194526 T DK 18194526T DK 3446695 T3 DK3446695 T3 DK 3446695T3
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DK
Denmark
Prior art keywords
lively
soft gel
bacteries
probiotic
basis
Prior art date
Application number
DK18194526.2T
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English (en)
Inventor
Jessica Philipp
Original Assignee
Ayanda Gmbh
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
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Publication of DK3446695T3 publication Critical patent/DK3446695T3/da

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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/66Microorganisms or materials therefrom
    • A61K35/74Bacteria
    • A61K35/741Probiotics
    • A61K35/744Lactic acid bacteria, e.g. enterococci, pediococci, lactococci, streptococci or leuconostocs
    • A61K35/745Bifidobacteria
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/48Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/4816Wall or shell material
    • A61K9/4825Proteins, e.g. gelatin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/185Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19Carboxylic acids, e.g. valproic acid
    • A61K31/20Carboxylic acids, e.g. valproic acid having a carboxyl group bound to a chain of seven or more carbon atoms, e.g. stearic, palmitic, arachidic acids
    • A61K31/202Carboxylic acids, e.g. valproic acid having a carboxyl group bound to a chain of seven or more carbon atoms, e.g. stearic, palmitic, arachidic acids having three or more double bonds, e.g. linolenic
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/59Compounds containing 9, 10- seco- cyclopenta[a]hydrophenanthrene ring systems
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/56Materials from animals other than mammals
    • A61K35/60Fish, e.g. seahorses; Fish eggs
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/56Materials from animals other than mammals
    • A61K35/63Arthropods
    • A61K35/64Insects, e.g. bees, wasps or fleas
    • A61K35/644Beeswax; Propolis; Royal jelly; Honey
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/66Microorganisms or materials therefrom
    • A61K35/74Bacteria
    • A61K35/741Probiotics
    • A61K35/744Lactic acid bacteria, e.g. enterococci, pediococci, lactococci, streptococci or leuconostocs
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/30Boraginaceae (Borage family), e.g. comfrey, lungwort or forget-me-not
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/31Brassicaceae or Cruciferae (Mustard family), e.g. broccoli, cabbage or kohlrabi
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/45Ericaceae or Vacciniaceae (Heath or Blueberry family), e.g. blueberry, cranberry or bilberry
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/48Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/4833Encapsulating processes; Filling of capsules
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/48Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/4841Filling excipients; Inactive ingredients
    • A61K9/4858Organic compounds
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/48Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A61K9/5005Wall or coating material
    • A61K9/5021Organic macromolecular compounds
    • A61K9/5052Proteins, e.g. albumin
    • A61K9/5057Gelatin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/10Laxatives
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K2035/11Medicinal preparations comprising living procariotic cells
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K2035/11Medicinal preparations comprising living procariotic cells
    • A61K2035/115Probiotics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/48Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/4841Filling excipients; Inactive ingredients
    • A61K9/4875Compounds of unknown constitution, e.g. material from plants or animals

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Natural Medicines & Medicinal Plants (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Mycology (AREA)
  • Microbiology (AREA)
  • Engineering & Computer Science (AREA)
  • Botany (AREA)
  • Medical Informatics (AREA)
  • Biotechnology (AREA)
  • Alternative & Traditional Medicine (AREA)
  • Insects & Arthropods (AREA)
  • Molecular Biology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Animal Husbandry (AREA)
  • Zoology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Marine Sciences & Fisheries (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Medicinal Preparation (AREA)
  • Medicines Containing Plant Substances (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Coloring Foods And Improving Nutritive Qualities (AREA)
  • General Preparation And Processing Of Foods (AREA)
  • Medical Preparation Storing Or Oral Administration Devices (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
DK18194526.2T 2014-09-08 2015-09-08 Forbedret fremgangsmåde til fremstilling af en blød gelkapsel omfattende levedygtige probiotiske bakterier og en blød gelkapsel omfattende levedygtige probiotiske bakterier med en lang holdbarhed DK3446695T3 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GBGB1415862.0A GB201415862D0 (en) 2014-09-08 2014-09-08 Process
EP15766194.3A EP3177301B1 (en) 2014-09-08 2015-09-08 An improved process for producing a soft gel capsule comprising viable probiotic bacteria and a soft gel capsule comprising viable probiotic bacteria having a long shelf life

Publications (1)

Publication Number Publication Date
DK3446695T3 true DK3446695T3 (da) 2020-02-03

Family

ID=51796364

Family Applications (2)

Application Number Title Priority Date Filing Date
DK15766194.3T DK3177301T3 (da) 2014-09-08 2015-09-08 Forbedret fremgangsmåde til fremstilling af en blød gelkapsel omfattende levedygtige probiotiske bakterier og en blød gelkapsel omfattende levedygtige probiotiske bakterier med en lang holdbarhed
DK18194526.2T DK3446695T3 (da) 2014-09-08 2015-09-08 Forbedret fremgangsmåde til fremstilling af en blød gelkapsel omfattende levedygtige probiotiske bakterier og en blød gelkapsel omfattende levedygtige probiotiske bakterier med en lang holdbarhed

Family Applications Before (1)

Application Number Title Priority Date Filing Date
DK15766194.3T DK3177301T3 (da) 2014-09-08 2015-09-08 Forbedret fremgangsmåde til fremstilling af en blød gelkapsel omfattende levedygtige probiotiske bakterier og en blød gelkapsel omfattende levedygtige probiotiske bakterier med en lang holdbarhed

Country Status (10)

Country Link
US (1) US20170258857A1 (da)
EP (2) EP3177301B1 (da)
JP (1) JP2017529099A (da)
CN (1) CN106999439B (da)
DK (2) DK3177301T3 (da)
ES (2) ES2731816T3 (da)
GB (1) GB201415862D0 (da)
PL (2) PL3446695T3 (da)
TR (1) TR201908675T4 (da)
WO (1) WO2016038355A1 (da)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20180256505A1 (en) * 2017-03-09 2018-09-13 The Clorox Company Probiotic capsule and methods of preparing the same
US11896720B2 (en) * 2017-09-26 2024-02-13 Captek Softgel International Orally available articles containing at least one stabilized supplement therein
CN107594538B (zh) * 2017-10-20 2020-10-16 青岛伸东矿液有限公司 一种分子筛生物制剂及其制备方法
CN114245748A (zh) * 2019-06-13 2022-03-25 莱托生物股份有限公司 包含活微生物的凝胶组合物
GR1010228B (el) * 2020-12-09 2022-05-05 UNI-PHARMA ΚΛΕΩΝ ΤΣΕΤΗΣ ΦΑΡΜΑΚΕΥΤΙΚΑ ΕΡΓΑΣΤΗΡΙΑ ΑΒΕΕ με δ.τ. "UNI-PHARMA ABEE", Διατροφικο συμπληρωμα για την απο του στοματος χορηγηση συνδυασμου βιταμινων, μεταλλων, φυσικων εκχυλισματων, προβιοτικων για την ενισχυση του ανοσοποιητικου συστηματος
BE1030385B1 (fr) * 2022-03-24 2023-10-23 Bellavie Capsules à usage par voie orale comprenant une formulation à base de probiotiques, conditionnées en dose unitaire dans un emballage-coque stratifié

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2127392C (en) * 1993-07-08 2008-05-27 Hideki Sunohara Process for producing capsule and capsule obtained thereby
US7214370B2 (en) * 2000-12-18 2007-05-08 Probiohealth, Llc Prebiotic and preservative uses of oil-emulsified probiotic encapsulations
US20030138483A1 (en) * 2001-05-25 2003-07-24 Sergio Petriconi Soft elastic capsules and compositions thereof
US20100055083A1 (en) * 2006-10-18 2010-03-04 Ray Edward Kowalski Encapsulation of heat and moisture sensitive substances
CA2675892A1 (en) * 2007-01-20 2008-07-24 Merck Patent Gesellschaft Mit Beschraenkter Haftung Pack containing soft capsules
GB0801643D0 (en) * 2008-01-29 2008-03-05 Probio Nutraceuticals As Product
CA3065589C (en) * 2010-06-03 2022-04-26 Catalent Ontario Limited Multi phase soft gel capsules, apparatus and method thereof
US20120107395A1 (en) * 2010-11-01 2012-05-03 Viva Pharmaceutical Inc. Probiotic Soft Gel Compositions

Also Published As

Publication number Publication date
WO2016038355A1 (en) 2016-03-17
EP3177301A1 (en) 2017-06-14
CN106999439B (zh) 2021-01-08
CN106999439A (zh) 2017-08-01
GB201415862D0 (en) 2014-10-22
EP3446695A1 (en) 2019-02-27
TR201908675T4 (tr) 2019-07-22
EP3446695B1 (en) 2019-10-30
ES2769302T3 (es) 2020-06-25
PL3177301T3 (pl) 2019-10-31
US20170258857A1 (en) 2017-09-14
PL3446695T3 (pl) 2020-05-18
DK3177301T3 (da) 2019-06-17
EP3177301B1 (en) 2019-03-20
JP2017529099A (ja) 2017-10-05
ES2731816T3 (es) 2019-11-19

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