DK3170842T3 - Immunologisk effektorcelle af målrettet cld18a2, fremstillingsfremgangsmåde og anvendelse deraf - Google Patents

Immunologisk effektorcelle af målrettet cld18a2, fremstillingsfremgangsmåde og anvendelse deraf Download PDF

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Publication number
DK3170842T3
DK3170842T3 DK15821331.4T DK15821331T DK3170842T3 DK 3170842 T3 DK3170842 T3 DK 3170842T3 DK 15821331 T DK15821331 T DK 15821331T DK 3170842 T3 DK3170842 T3 DK 3170842T3
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cld18a2
targeted
preparation
application
effect cell
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DK15821331.4T
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Huamao Wang
Bo Song
Xiumei Cai
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Carsgen Therapeutics Ltd
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    • C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
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    • C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
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    • A61K39/46—Cellular immunotherapy
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    • A61K39/4611—T-cells, e.g. tumor infiltrating lymphocytes [TIL], lymphokine-activated killer cells [LAK] or regulatory T cells [Treg]
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DK15821331.4T 2014-07-17 2015-07-15 Immunologisk effektorcelle af målrettet cld18a2, fremstillingsfremgangsmåde og anvendelse deraf DK3170842T3 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
CN201410341504.XA CN105315375B (zh) 2014-07-17 2014-07-17 靶向cld18a2的t淋巴细胞及其制备方法和应用
PCT/CN2015/084023 WO2016008405A1 (zh) 2014-07-17 2015-07-15 靶向cld18a2的免疫效应细胞及其制备方法和应用

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DK3170842T3 true DK3170842T3 (da) 2019-10-07

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ID=55077917

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DK15821331.4T DK3170842T3 (da) 2014-07-17 2015-07-15 Immunologisk effektorcelle af målrettet cld18a2, fremstillingsfremgangsmåde og anvendelse deraf

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Country Link
US (3) US10377822B2 (da)
EP (1) EP3170842B1 (da)
JP (2) JP2017522024A (da)
KR (1) KR101950747B1 (da)
CN (2) CN105315375B (da)
DK (1) DK3170842T3 (da)
ES (1) ES2746555T3 (da)
PL (1) PL3170842T3 (da)
PT (1) PT3170842T (da)
WO (1) WO2016008405A1 (da)

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CN105315375B (zh) * 2014-07-17 2021-04-23 恺兴生命科技(上海)有限公司 靶向cld18a2的t淋巴细胞及其制备方法和应用
WO2016180468A1 (en) * 2015-05-11 2016-11-17 Biontech Cell & Gene Therapies Gmbh Claudin-18.2-specific immunoreceptors and t cell epitopes
CN109414512A (zh) 2016-04-22 2019-03-01 科济生物医药（上海）有限公司 用于细胞免疫疗法的组合物和方法
BR112018075032A2 (pt) 2016-06-15 2019-03-26 Icahn School Of Medicine At Mount Sinai proteínas de hemaglutinina do vírus influenza e seus uso
CN107523549A (zh) * 2016-06-20 2017-12-29 上海细胞治疗研究院 一种高效稳定表达激活型抗体的car‑t细胞及其用途
KR20190038564A (ko) * 2016-07-08 2019-04-08 카르스젠 테라퓨틱스 컴퍼니, 리미티드 항클라우딘 18a2의 항체 및 이의 응용
CN109844125A (zh) * 2016-08-31 2019-06-04 南京凯地生物科技有限公司 人pd-1基因敲除的cldn18．2特异性嵌合抗原受体t细胞的制备方法以及应用
CN106754725A (zh) * 2016-12-26 2017-05-31 北京普瑞金科技有限公司 一种嵌合抗原受体t细胞及其制备方法与应用
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CN111989344A (zh) * 2018-03-09 2020-11-24 科济生物医药（上海）有限公司 用于治疗肿瘤的方法和组合物
EP3789486A4 (en) 2018-05-03 2022-03-30 Cafa Therapeutics Limited MANIPULATED IMMUNE EFFECTOR CELLS AND USE THEREOF
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WO2019242505A1 (zh) 2018-06-17 2019-12-26 上海健信生物医药科技有限公司 靶向cldn18.2的抗体、双特异性抗体、adc和car及其应用
CN110615842B (zh) * 2018-06-20 2023-05-09 上海隆耀生物科技有限公司 一种包含共刺激受体的嵌合抗原受体及应用
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WO2020114518A1 (zh) 2018-12-07 2020-06-11 科济生物医药（上海）有限公司 肿瘤联合免疫治疗
JP2022515487A (ja) * 2018-12-28 2022-02-18 ナンジン、ジェンスクリプト、バイオテック、カンパニー、リミテッド クローディン１８．２結合部分およびその利用
WO2020143631A1 (zh) 2019-01-07 2020-07-16 科济生物医药（上海）有限公司 细胞免疫治疗的组合
CN111434692B (zh) * 2019-01-15 2021-12-31 浙江道尔生物科技有限公司 抗cld18a2纳米抗体及其应用
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