DK3383403T3 - Aminofosfonisk derivat til forebyggelse og behandling af øjesmerter - Google Patents

Aminofosfonisk derivat til forebyggelse og behandling af øjesmerter Download PDF

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Publication number
DK3383403T3
DK3383403T3 DK16809676.6T DK16809676T DK3383403T3 DK 3383403 T3 DK3383403 T3 DK 3383403T3 DK 16809676 T DK16809676 T DK 16809676T DK 3383403 T3 DK3383403 T3 DK 3383403T3
Authority
DK
Denmark
Prior art keywords
aminophosphonic
derivative
prevention
treatment
eye pain
Prior art date
Application number
DK16809676.6T
Other languages
Danish (da)
English (en)
Inventor
Michel Wurm
Goazigo Annabelle Reaux-Le
Hervé Poras
Parsadaniantz Stéphane Melik
Original Assignee
Pharmaleads
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pharmaleads filed Critical Pharmaleads
Application granted granted Critical
Publication of DK3383403T3 publication Critical patent/DK3383403T3/da

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Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/66—Phosphorus compounds
    • A61K31/662—Phosphorus acids or esters thereof having P—C bonds, e.g. foscarnet, trichlorfon
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/715—Polysaccharides, i.e. having more than five saccharide radicals attached to each other by glycosidic linkages; Derivatives thereof, e.g. ethers, esters
    • A61K31/716—Glucans
    • A61K31/724—Cyclodextrins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/36—Polysaccharides; Derivatives thereof, e.g. gums, starch, alginate, dextrin, hyaluronic acid, chitosan, inulin, agar or pectin
    • A61K47/40—Cyclodextrins; Derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0048—Eye, e.g. artificial tears
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0048—Eye, e.g. artificial tears
    • A61K9/0051—Ocular inserts or implants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/06—Ointments; Bases therefor; Other semi-solid forms, e.g. creams, sticks, gels
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/08—Solutions
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Ophthalmology & Optometry (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Inorganic Chemistry (AREA)
  • Molecular Biology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Biochemistry (AREA)
DK16809676.6T 2015-11-30 2016-11-30 Aminofosfonisk derivat til forebyggelse og behandling af øjesmerter DK3383403T3 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
FR1561598A FR3044227B1 (fr) 2015-11-30 2015-11-30 Derives aminophosphiniques pour la prevention et le traitement des douleurs oculaires
PCT/EP2016/079285 WO2017093322A1 (fr) 2015-11-30 2016-11-30 Dérivés aminophosphiniques pour la prévention et le traitement des douleurs oculaires

Publications (1)

Publication Number Publication Date
DK3383403T3 true DK3383403T3 (da) 2020-03-16

Family

ID=55346018

Family Applications (1)

Application Number Title Priority Date Filing Date
DK16809676.6T DK3383403T3 (da) 2015-11-30 2016-11-30 Aminofosfonisk derivat til forebyggelse og behandling af øjesmerter

Country Status (15)

Country Link
US (2) US20180344753A1 (enExample)
EP (1) EP3383403B1 (enExample)
JP (1) JP6889176B2 (enExample)
KR (1) KR102657652B1 (enExample)
CN (2) CN112121008A (enExample)
BR (1) BR112018010007A2 (enExample)
CA (1) CA3006365A1 (enExample)
DK (1) DK3383403T3 (enExample)
ES (1) ES2773148T3 (enExample)
FR (1) FR3044227B1 (enExample)
IL (1) IL259562B (enExample)
MX (1) MX382921B (enExample)
TW (1) TWI729039B (enExample)
WO (1) WO2017093322A1 (enExample)
ZA (1) ZA201804037B (enExample)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US9993427B2 (en) * 2013-03-14 2018-06-12 Biorest Ltd. Liposome formulation and manufacture
EP3592361B1 (fr) * 2017-03-09 2023-09-13 IACTA Pharmaceuticals, Inc. Dérivés aminophosphiniques pour la prévention et le traitement de l'inflammation oculaire
FR3063635B1 (fr) * 2017-03-09 2019-06-07 Pharmaleads Derives aminophosphiniques pour la prevention et le traitement de l'inflammation oculaire
FR3104581B1 (fr) * 2019-12-11 2021-11-26 Pharmaleads Procédé de préparation industrielle du sel disodique de ((2S)-3-([1,1'-biphenyl]-4-yl)-2-((hydroxy((1R)-1-(((1-(isobutyryloxy)ethoxy)carbonyl)amino)ethyl)phosphoryl) methyl)propanoyl)-L-alanine

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH0987291A (ja) * 1995-09-26 1997-03-31 Wakamoto Pharmaceut Co Ltd 新規なアラニン誘導体
FR2755135B1 (fr) * 1996-10-25 2002-12-27 Inst Nat Sante Rech Med Nouveaux derives d'(alpha-aminophosphino)peptides, leur procede de preparation et les compositions qui les contiennent
CA2275167C (en) * 1996-12-16 2008-10-28 Alcon Laboratories, Inc. The topical use of kappa opioid agonists to treat ocular pain
FR2777780B1 (fr) * 1998-04-22 2001-05-04 Inst Nat Sante Rech Med Derives d'(alpha-aminophosphino) peptides, leur procede de preparation et les compositions qui les contiennent
FR2934267B1 (fr) * 2008-07-23 2010-08-13 Pharmaleads Derives aminophosphiniques utiles dans le traitement de la douleur
FR2934627B1 (fr) 2008-07-29 2010-08-13 Paul Marie Bernard Dispositif de positionnement et de calage d'un garde corps escamotable sur plateforme support de banches
KR20150119082A (ko) * 2013-02-13 2015-10-23 노파르티스 아게 국소 안구 진통제

Also Published As

Publication number Publication date
WO2017093322A1 (fr) 2017-06-08
FR3044227B1 (fr) 2017-11-24
IL259562A (en) 2018-07-31
EP3383403B1 (fr) 2019-12-25
JP6889176B2 (ja) 2021-06-18
CA3006365A1 (fr) 2017-06-08
TWI729039B (zh) 2021-06-01
MX2018006580A (es) 2018-08-01
ES2773148T3 (es) 2020-07-09
CN108289901A (zh) 2018-07-17
KR20180095555A (ko) 2018-08-27
IL259562B (en) 2020-08-31
US20190167701A1 (en) 2019-06-06
BR112018010007A2 (pt) 2018-11-21
ZA201804037B (en) 2020-07-29
FR3044227A1 (fr) 2017-06-02
CN112121008A (zh) 2020-12-25
KR102657652B1 (ko) 2024-04-15
MX382921B (es) 2025-03-13
JP2018536714A (ja) 2018-12-13
HK1259181A1 (zh) 2019-11-29
US20180344753A1 (en) 2018-12-06
TW201726146A (zh) 2017-08-01
EP3383403A1 (fr) 2018-10-10
US10688113B2 (en) 2020-06-23
CN108289901B (zh) 2021-05-04

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