DK3364958T3 - Modulatorer af sestrin-gator2-interaktion og anvendelser deraf - Google Patents
Modulatorer af sestrin-gator2-interaktion og anvendelser deraf Download PDFInfo
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- DK3364958T3 DK3364958T3 DK16858326.8T DK16858326T DK3364958T3 DK 3364958 T3 DK3364958 T3 DK 3364958T3 DK 16858326 T DK16858326 T DK 16858326T DK 3364958 T3 DK3364958 T3 DK 3364958T3
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- sestrin
- modulators
- applications
- gator2 interaction
- gator2
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- 230000003993 interaction Effects 0.000 title 1
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- C07C229/12—Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated having only one amino and one carboxyl group bound to the carbon skeleton the nitrogen atom of the amino group being further bound to acyclic carbon atoms or to carbon atoms of rings other than six-membered aromatic rings to carbon atoms of acyclic carbon skeletons
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| EP4556069A3 (en) | 2017-04-26 | 2025-08-13 | Navitor Pharmaceuticals, Inc. | Modulators of sestrin-gator2 interaction and uses thereof |
| JP7644002B2 (ja) | 2018-10-24 | 2025-03-11 | ナビター ファーマシューティカルズ, インコーポレイテッド | 多形化合物およびその使用 |
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| KR102641718B1 (ko) | 2018-10-30 | 2024-02-29 | 길리애드 사이언시즈, 인코포레이티드 | 알파4베타7 인테그린 억제제로서의 이미다조피리딘 유도체 |
| CN112996786B (zh) | 2018-10-30 | 2024-08-20 | 吉利德科学公司 | 用于抑制α4β7整合素的化合物 |
| KR102659859B1 (ko) | 2018-10-30 | 2024-04-25 | 길리애드 사이언시즈, 인코포레이티드 | 알파4β7 인테그린의 억제를 위한 화합물 |
| CN111689993B (zh) * | 2019-03-11 | 2023-04-14 | 凯特立斯(深圳)科技有限公司 | 一种新的含硼类佐米药物关键中间体手性α-氨基硼酸酯的制备方法 |
| CN119431230A (zh) | 2019-08-14 | 2025-02-14 | 吉利德科学公司 | 用于抑制α4β7整合素的化合物 |
| CN114786660A (zh) * | 2019-11-01 | 2022-07-22 | 纳维托制药有限公司 | 使用mtorc1调节剂的治疗方法 |
| CN112699498B (zh) * | 2021-03-23 | 2021-05-25 | 中国空气动力研究与发展中心计算空气动力研究所 | 基于归一化物理量间断特征的喷流模拟激波快速判别方法 |
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| WO2013142229A1 (en) * | 2012-03-19 | 2013-09-26 | President And Fellows Of Harvard College | Designing novel peptides for inducing fibronectin matrix assembly |
| KR102124392B1 (ko) | 2012-08-06 | 2020-06-19 | 피트니 파마슈티컬스 피티와이 리미티드 | mTOR 경로 관련 질병 치료를 위한 화합물 |
| US20160002159A1 (en) * | 2013-02-13 | 2016-01-07 | Neal ZONDLO | Perfluoro-tert-butyl hydroxyproline |
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| US20180327364A1 (en) | 2015-11-13 | 2018-11-15 | Brandeis University | Mtor inhibitors and methods of use thereof |
| US10512656B2 (en) | 2016-04-21 | 2019-12-24 | Baylor College Of Medicine | Compositions and methods for the treatment of lysosomal storage disorders and disorders characterized by lysosomal dysfunction |
| EP4556069A3 (en) | 2017-04-26 | 2025-08-13 | Navitor Pharmaceuticals, Inc. | Modulators of sestrin-gator2 interaction and uses thereof |
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| JP7644002B2 (ja) | 2018-10-24 | 2025-03-11 | ナビター ファーマシューティカルズ, インコーポレイテッド | 多形化合物およびその使用 |
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