DK32786A - Anvendelse af dipeptidderivater til fremstilling af laegemidler til behandling af posttraumatiske nerveskader - Google Patents
Anvendelse af dipeptidderivater til fremstilling af laegemidler til behandling af posttraumatiske nerveskader Download PDFInfo
- Publication number
- DK32786A DK32786A DK32786A DK32786A DK32786A DK 32786 A DK32786 A DK 32786A DK 32786 A DK32786 A DK 32786A DK 32786 A DK32786 A DK 32786A DK 32786 A DK32786 A DK 32786A
- Authority
- DK
- Denmark
- Prior art keywords
- treatment
- stands
- hydrogen atom
- dipeptide derivatives
- posttraumatic
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
- C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
- C07K5/08—Tripeptides
- C07K5/0821—Tripeptides with the first amino acid being heterocyclic, e.g. His, Pro, Trp
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/54—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one sulfur as the ring hetero atoms, e.g. sulthiame
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/04—Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
- A61K38/06—Tripeptides
- A61K38/066—TRH, thyroliberin, thyrotropin releasing hormone
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P5/00—Drugs for disorders of the endocrine system
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Organic Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Epidemiology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Neurology (AREA)
- General Chemical & Material Sciences (AREA)
- Biomedical Technology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Neurosurgery (AREA)
- Endocrinology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Biophysics (AREA)
- Molecular Biology (AREA)
- Genetics & Genomics (AREA)
- Gastroenterology & Hepatology (AREA)
- Immunology (AREA)
- Biochemistry (AREA)
- Diabetes (AREA)
- Psychiatry (AREA)
- Hospice & Palliative Care (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Peptides Or Proteins (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
DE3502041 | 1985-01-23 | ||
DE19853502041 DE3502041A1 (de) | 1985-01-23 | 1985-01-23 | Verwendung von dipeptidderivaten zur behandlung posttraumatischer nervenschaeden |
Publications (4)
Publication Number | Publication Date |
---|---|
DK32786D0 DK32786D0 (da) | 1986-01-22 |
DK32786A true DK32786A (da) | 1986-07-24 |
DK165733B DK165733B (da) | 1993-01-11 |
DK165733C DK165733C (da) | 1993-06-07 |
Family
ID=6260477
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DK032786A DK165733C (da) | 1985-01-23 | 1986-01-22 | Anvendelse af dipeptiderivater til fremstilling a f laegemidler til forhindring eller behandling af posttraumatiske nerveskader efter ved uheld fremkaldte rygmarvs- og/eller hjernetraumer. |
Country Status (11)
Country | Link |
---|---|
US (1) | US4906614A (da) |
EP (1) | EP0188810B1 (da) |
JP (1) | JPS61172828A (da) |
AT (1) | ATE57834T1 (da) |
AU (1) | AU578999B2 (da) |
DE (2) | DE3502041A1 (da) |
DK (1) | DK165733C (da) |
IE (1) | IE58805B1 (da) |
IL (1) | IL77218A (da) |
SG (1) | SG83791G (da) |
ZA (1) | ZA859187B (da) |
Families Citing this family (24)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
GB2219501B (en) * | 1987-04-08 | 1990-09-26 | Nippon Shinyaku Co Ltd | Nootropic agent. |
US5686420A (en) * | 1987-06-05 | 1997-11-11 | Georgetown University | Thyrotropin-releasing hormone analogs and method of use |
JPS63316724A (ja) * | 1987-06-19 | 1988-12-26 | Nippon Shinyaku Co Ltd | 抗けいれん剤 |
US5049553A (en) * | 1990-01-04 | 1991-09-17 | E. R. Squibb & Sons, Inc. | Method for preventing or treating symptoms resulting from closed head injuries employing an ace inhibitor |
US6812208B2 (en) | 1993-12-23 | 2004-11-02 | Neuronz Ltd. | Methods to improve neural outcome |
CA2178711A1 (en) * | 1993-12-23 | 1995-06-29 | Peter David Gluckman | Composition and methods to improve neural outcome |
US5897858A (en) | 1994-02-03 | 1999-04-27 | Schering-Plough Healthcare Products, Inc. | Nasal spray compositions exhibiting increased retention in the nasal cavity |
US6187906B1 (en) * | 1997-08-11 | 2001-02-13 | Aukland Uniservices Limited | Methods to improve neural outcome |
US20020151502A1 (en) * | 1997-10-09 | 2002-10-17 | Albert Sattin | Tri-peptides for neurological and neurobehavior applications |
US6475989B1 (en) | 1997-10-09 | 2002-11-05 | Albert Sattin | Use of pyroglutamyl-glutamyl-prolyl amide (EEP) for neurological and neurobehavioral disorders |
US20050233973A1 (en) * | 1997-10-09 | 2005-10-20 | Albert Sattin | Tri-peptides for antidepressant applications |
WO2001028578A2 (en) * | 1999-10-22 | 2001-04-26 | Wrair | A PHARMACEUTICAL COMPOSITION CONTAINING pGLU-GLU-PRO-NH2 AND METHOD FOR TREATING DISEASES AND INJURIES TO THE BRAIN, SPINAL CORD AND RETINA USING SAME |
US6815425B1 (en) | 1999-10-22 | 2004-11-09 | The United States Of America As Represented By The Secretary Of The Army | Pharmaceutical composition containing pGLU-GLU-PRO-NH2 and method for treating diseases and injuries to the brain, spinal cord and retina using same |
IE20000240A1 (en) * | 2000-02-17 | 2003-03-05 | Trinity College Dublin | TRH-like peptide derivatives |
US7112570B2 (en) * | 2000-08-24 | 2006-09-26 | Neuren Pharmaceuticals, Ltd. | GPE analogs |
WO2002016408A2 (en) * | 2000-08-24 | 2002-02-28 | Neuronz Ltd. | Gpe analogs |
US7605177B2 (en) * | 2001-05-24 | 2009-10-20 | Neuren Pharmaceuticals Limited | Effects of glycyl-2 methyl prolyl glutamate on neurodegeneration |
US7714020B2 (en) * | 2001-05-24 | 2010-05-11 | Neuren Pharmaceuticals Limited | Treatment of non-convulsive seizures in brain injury using G-2-methyl-prolyl glutamate |
US20070004641A1 (en) * | 2001-05-24 | 2007-01-04 | Neuren Pharmaceuticals Limited | Cognitive enhancement and cognitive therapy using glycyl-L-2-methylprolyl-L-glutamate |
ATE435852T1 (de) | 2001-05-24 | 2009-07-15 | Neuren Pharmaceuticals Ltd | Gpe-analoga und peptidomimetika |
US8791117B2 (en) | 2003-09-03 | 2014-07-29 | Neuren Pharmaceuticals Limited | Cyclic glycyl-2-allyl proline improves cognitive performance in impaired animals |
US7462595B2 (en) * | 2004-09-17 | 2008-12-09 | Prange Jr Arthur Jergen | Methods for treating cancer-related fatigue |
EP1794182B1 (en) * | 2004-10-01 | 2015-06-03 | The Provost, Fellows and Scholars of the College of the Holy and Undivided Trinity of Queen Elizabeth near Dublin | Compounds that modulate trh actions and inhibit the trh-degrading enzyme |
JP6574769B2 (ja) | 2013-07-25 | 2019-09-11 | ニューレン ファーマシューティカルズ リミテッド | 二環式化合物ならびに自閉症スペクトラム障害および神経発達障害の治療におけるそれらの使用方法 |
Family Cites Families (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE2449167C2 (de) | 1974-10-16 | 1984-05-24 | Grünenthal GmbH, 5190 Stolberg | N-Acyl-L-histidyl-L-prolinamide, Verfahren zu deren Herstellung und diese Verbindungen enthaltende pharmazeutische Zubereitungen |
DE2615455C2 (de) * | 1976-04-09 | 1985-06-20 | Grünenthal GmbH, 5190 Stolberg | N-Acyl-L-histidyl-L-prolin (N-substituierte)-amide, Verfahren zu deren Herstellung und diese Verbindungen enthaltende pharmazeutische Zubereitungen |
US4608365A (en) * | 1984-03-30 | 1986-08-26 | University Of Southern California | Treatment of neurologic functions |
-
1985
- 1985-01-23 DE DE19853502041 patent/DE3502041A1/de not_active Withdrawn
- 1985-11-19 IE IE290585A patent/IE58805B1/en not_active IP Right Cessation
- 1985-11-29 ZA ZA859187A patent/ZA859187B/xx unknown
- 1985-12-03 IL IL77218A patent/IL77218A/xx not_active IP Right Cessation
- 1985-12-23 AT AT85116530T patent/ATE57834T1/de not_active IP Right Cessation
- 1985-12-23 EP EP85116530A patent/EP0188810B1/de not_active Expired - Lifetime
- 1985-12-23 DE DE8585116530T patent/DE3580351D1/de not_active Expired - Fee Related
-
1986
- 1986-01-22 AU AU52601/86A patent/AU578999B2/en not_active Ceased
- 1986-01-22 DK DK032786A patent/DK165733C/da not_active IP Right Cessation
- 1986-01-23 JP JP61011187A patent/JPS61172828A/ja active Granted
-
1988
- 1988-06-14 US US07/207,115 patent/US4906614A/en not_active Expired - Lifetime
-
1991
- 1991-10-11 SG SG837/91A patent/SG83791G/en unknown
Also Published As
Publication number | Publication date |
---|---|
IE852905L (en) | 1986-07-23 |
US4906614A (en) | 1990-03-06 |
DE3580351D1 (de) | 1990-12-06 |
IL77218A (en) | 1990-11-05 |
ZA859187B (en) | 1986-08-27 |
DK165733C (da) | 1993-06-07 |
DE3502041A1 (de) | 1986-07-24 |
ATE57834T1 (de) | 1990-11-15 |
JPH0584286B2 (da) | 1993-12-01 |
DK165733B (da) | 1993-01-11 |
IE58805B1 (en) | 1993-11-17 |
SG83791G (en) | 1991-11-22 |
AU5260186A (en) | 1986-07-31 |
JPS61172828A (ja) | 1986-08-04 |
EP0188810B1 (de) | 1990-10-31 |
DK32786D0 (da) | 1986-01-22 |
AU578999B2 (en) | 1988-11-10 |
EP0188810A2 (de) | 1986-07-30 |
EP0188810A3 (en) | 1988-09-07 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
DK32786A (da) | Anvendelse af dipeptidderivater til fremstilling af laegemidler til behandling af posttraumatiske nerveskader | |
DE3164764D1 (en) | 1,1,2-triphenyl-but-1-ene derivatives, process for their manufacture and their use as pharmaceutical agents | |
MY100343A (en) | Amide derivative and external medicament comprising same | |
AU8169287A (en) | New diphosphonic acid derivatives, processes for the preparation thereof and pharmaceutical compositions containing them | |
DK0421561T3 (da) | 24-homo-vitamin-D-derivater, fremgangsmåder til fremstilling heraf, farmaceutiske præparater indeholdende disse derivater samt deres anvendelse som lægemiddel | |
IL111581A (en) | Cyclic amino acid derivatives pharmaceutical compositions containing them and process for their preparation | |
ES2039196T3 (es) | Procedimiento para preparar 4-(1,2,5,6-tetrahidro-1-alquil-3-piridinil)-2-tiazolaminas y 4-(hexahidro-1-alquil-3-piridinil)-2-tiazolaminas. | |
DE58904337D1 (de) | Arzneimittel enthaltend nitroxyalkylamine mit amidfunktion und verfahren zur herstellung dieser verbindungen. | |
ES2109216T3 (es) | Un procedimiento para la preparacion de una composicion farmaceutica con actividad relajante muscular de accion central. | |
HK1000284A1 (en) | N-(5,6,7,8-tetrahydropyrido(2,3D)pyrimidin-6-Yl-alkanoyl)-glutamic acid derivatives | |
DE3775496D1 (de) | Benzhydryloxyaethyl-piperidine-derivate, verfahren zur herstellung und pharmazeutische zusammenstellungen, die diese enthalten. | |
EP0228314A3 (en) | Use of ethanol/amine derivatives in treating or preventing hyperlipemia | |
ES557149A0 (es) | Un procedimiento para la preparacion de derivados peptidicos de histidinilprolinamida. | |
ES487631A1 (es) | Procedimiento para la obtencion de hexahidro-1,4-oxazepinas | |
EP0334674A3 (en) | Use of isoxazolinones as cerebro-active drugs | |
IE863088L (en) | Peptide immunostimulants | |
ES2027492A6 (es) | Procedimiento de preparacion de nuevos derivados dihidropirimidotiazinos y de sus sales de adicion acidas farmaceuticamente aceptables. | |
EP0220654A3 (en) | Gonadoliberine analogues, process for preparing them, pharmaceutical composition and use | |
ES2058315T3 (es) | Compuestos eficaces contra insuficiencia cerebral. | |
GB1313838A (en) | 3,4,5-trialkoxybenzoic acid derivatives and their uses | |
ES8704477A1 (es) | Procedimiento para preparar piridin-1-oxidos varias veces substituidos | |
TH1819B (th) | การเตรียมอนุพันธ์ 1-แอลคิล-2-อะมิโน-เททราลิน | |
ES477164A1 (es) | Un procedimiento de preparacion de 6-ciclopropil-1,3-dihi- dro-5-fenil-2-oxo-2h-tieno (2,3-e) diazepina. | |
LTIP1787A (en) | Novel acrylic amide derivatives, aprocess for their preparation, pharmaceutical compositions containing the same and their use in medicine | |
FR2633292B1 (fr) | Nouveaux derives de la 20,21-dinoreburnamenine substitues en 15 par un groupement amine, leur procede de preparation et les intermediaires ainsi obtenus, leur application comme medicaments et les compositions pharmaceutiques les reenfermant |
Legal Events
Date | Code | Title | Description |
---|---|---|---|
PBP | Patent lapsed |