DK3266792T3 - Fremgangsmåde til peptidsyntese - Google Patents
Fremgangsmåde til peptidsyntese Download PDFInfo
- Publication number
- DK3266792T3 DK3266792T3 DK16758925.8T DK16758925T DK3266792T3 DK 3266792 T3 DK3266792 T3 DK 3266792T3 DK 16758925 T DK16758925 T DK 16758925T DK 3266792 T3 DK3266792 T3 DK 3266792T3
- Authority
- DK
- Denmark
- Prior art keywords
- peptide synthesis
- peptide
- synthesis
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
- C07K1/02—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length in solution
- C07K1/026—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length in solution by fragment condensation in solution
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C217/00—Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton
- C07C217/54—Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton having etherified hydroxy groups bound to carbon atoms of at least one six-membered aromatic ring and amino groups bound to acyclic carbon atoms or to carbon atoms of rings other than six-membered aromatic rings of the same carbon skeleton
- C07C217/56—Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton having etherified hydroxy groups bound to carbon atoms of at least one six-membered aromatic ring and amino groups bound to acyclic carbon atoms or to carbon atoms of rings other than six-membered aromatic rings of the same carbon skeleton with amino groups linked to the six-membered aromatic ring, or to the condensed ring system containing that ring, by carbon chains not further substituted by singly-bound oxygen atoms
- C07C217/58—Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton having etherified hydroxy groups bound to carbon atoms of at least one six-membered aromatic ring and amino groups bound to acyclic carbon atoms or to carbon atoms of rings other than six-membered aromatic rings of the same carbon skeleton with amino groups linked to the six-membered aromatic ring, or to the condensed ring system containing that ring, by carbon chains not further substituted by singly-bound oxygen atoms with amino groups and the six-membered aromatic ring, or the condensed ring system containing that ring, bound to the same carbon atom of the carbon chain
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C43/00—Ethers; Compounds having groups, groups or groups
- C07C43/02—Ethers
- C07C43/20—Ethers having an ether-oxygen atom bound to a carbon atom of a six-membered aromatic ring
- C07C43/225—Ethers having an ether-oxygen atom bound to a carbon atom of a six-membered aromatic ring containing halogen
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C43/00—Ethers; Compounds having groups, groups or groups
- C07C43/02—Ethers
- C07C43/20—Ethers having an ether-oxygen atom bound to a carbon atom of a six-membered aromatic ring
- C07C43/23—Ethers having an ether-oxygen atom bound to a carbon atom of a six-membered aromatic ring containing hydroxy or O-metal groups
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
- C07K1/10—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length using coupling agents
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
- C07K1/14—Extraction; Separation; Purification
- C07K1/30—Extraction; Separation; Purification by precipitation
- C07K1/306—Extraction; Separation; Purification by precipitation by crystallization
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Analytical Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Biochemistry (AREA)
- Biophysics (AREA)
- General Health & Medical Sciences (AREA)
- Genetics & Genomics (AREA)
- Medicinal Chemistry (AREA)
- Molecular Biology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Crystallography & Structural Chemistry (AREA)
- Peptides Or Proteins (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2015042651 | 2015-03-04 | ||
| PCT/JP2016/056319 WO2016140232A1 (fr) | 2015-03-04 | 2016-03-02 | Procédé de synthèse peptidique |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| DK3266792T3 true DK3266792T3 (da) | 2021-02-01 |
Family
ID=56848267
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DK16758925.8T DK3266792T3 (da) | 2015-03-04 | 2016-03-02 | Fremgangsmåde til peptidsyntese |
Country Status (8)
| Country | Link |
|---|---|
| US (1) | US11098078B2 (fr) |
| EP (1) | EP3266792B1 (fr) |
| JP (1) | JP6713983B2 (fr) |
| CN (1) | CN107406480B (fr) |
| DK (1) | DK3266792T3 (fr) |
| ES (1) | ES2864924T3 (fr) |
| TW (1) | TW201639867A (fr) |
| WO (1) | WO2016140232A1 (fr) |
Families Citing this family (28)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2017112809A1 (fr) | 2015-12-21 | 2017-06-29 | Taxas Tech University System | Système et procédé de synthèse de peptides gap en phase solution |
| KR20200041993A (ko) | 2017-08-31 | 2020-04-22 | 다이이찌 산쿄 가부시키가이샤 | 항체-약물 콘주게이트의 개량 제조 방법 |
| CN111491941B (zh) * | 2017-12-19 | 2023-08-08 | 积水医疗株式会社 | 新型烷基二苯甲烷保护剂 |
| JP6531235B1 (ja) * | 2017-12-19 | 2019-06-12 | 積水メディカル株式会社 | 新規アルキルジフェニルメタン保護剤 |
| CN109988056B (zh) * | 2017-12-29 | 2020-08-07 | 深圳翰宇药业股份有限公司 | 一种用于多肽液相合成载体的化合物及其制备方法和用途 |
| EP3778621B1 (fr) * | 2018-04-13 | 2023-08-23 | Jitsubo Co., Ltd. | Procédé de synthèse peptidique |
| JP6703669B2 (ja) * | 2018-04-13 | 2020-06-03 | Jitsubo株式会社 | リュープロレリンの製造方法 |
| JP7394749B2 (ja) | 2018-05-10 | 2023-12-08 | 日本新薬株式会社 | オリゴ核酸化合物の製造方法 |
| US12024537B2 (en) | 2018-05-31 | 2024-07-02 | Sederma | Compositions and methods for chemical synthesis |
| CN109678751A (zh) * | 2019-01-07 | 2019-04-26 | 广州同隽医药科技有限公司 | 一种含有二苯甲烷结构的化合物 |
| EP3917937A4 (fr) | 2019-02-01 | 2022-11-23 | Sederma | Stratégie de synthèse pour groupe de protection gap |
| US11993629B2 (en) * | 2019-02-04 | 2024-05-28 | Nissan Chemical Corporation | Method for producing peptide compound |
| CN110256277B (zh) * | 2019-03-19 | 2020-12-15 | 广州同隽医药科技有限公司 | 一种含有芴环结构的化合物及其应用 |
| CN111825742B (zh) * | 2019-04-18 | 2024-01-30 | 陈铭 | Ctpa作为特种偶合剂用于氨基酸离子液体的多肽固相合成 |
| CN114981281A (zh) | 2019-11-13 | 2022-08-30 | 日本新药株式会社 | 寡核苷酸化合物的制造方法 |
| EP4059943A4 (fr) | 2019-11-13 | 2024-01-31 | Nippon Shinyaku Co., Ltd. | Procédé de production d'un composé d'acide oligonucléique |
| JPWO2021132545A1 (fr) * | 2019-12-27 | 2021-07-01 | ||
| JP7063408B1 (ja) | 2021-07-02 | 2022-05-09 | ペプチスター株式会社 | 液相ペプチド製造方法 |
| JP2024532301A (ja) | 2021-08-23 | 2024-09-05 | イーライ リリー アンド カンパニー | 液相合成のための化合物及び方法 |
| WO2023106356A1 (fr) * | 2021-12-08 | 2023-06-15 | 富士フイルム株式会社 | Procédé de production d'un composé peptidique, réactif permettant de former un groupe protecteur et composé benzylique substitué |
| JP7260725B1 (ja) * | 2021-12-27 | 2023-04-18 | 株式会社トクヤマ | ペプチド製造方法、保護基の除去方法、及び除去剤 |
| WO2023127331A1 (fr) * | 2021-12-27 | 2023-07-06 | 株式会社トクヤマ | Procédé de production de peptide, procédé d'élimination de groupe protecteur, agent d'élimination et composé benzylique |
| CN114315538B (zh) * | 2021-12-31 | 2023-10-20 | 杭州澳赛诺生物科技有限公司 | 一种作为多肽液相合成载体的苄醇酚醚类化合物及其制备方法与应用 |
| CN115626867B (zh) * | 2022-10-08 | 2023-11-14 | 瑞博(苏州)制药有限公司 | 一种非经典固相合成载体的制备及其在胸腺五肽合成中的应用 |
| WO2024128729A1 (fr) * | 2022-12-12 | 2024-06-20 | 주식회사 엘지생활건강 | Composition cosmétique pour l'amélioration de la peau |
| WO2024150477A1 (fr) * | 2023-01-13 | 2024-07-18 | 株式会社トクヤマ | Procédé de production d'un composé contenant un groupe amino, procédé de séparation d'un composé contenant un groupe amino, et appareil de production d'un composé contenant un groupe amino |
| JP7493115B1 (ja) | 2023-01-13 | 2024-05-30 | 株式会社トクヤマ | アミノ基含有化合物の製造方法、およびアミノ基含有化合物の分離方法 |
| CN116813693B (zh) * | 2023-08-29 | 2023-12-01 | 苏州金顶生物有限公司 | 一种用于多肽合成的标签化合物及其在多肽合成中的应用 |
Family Cites Families (15)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5516891A (en) | 1992-06-16 | 1996-05-14 | Kinerton, Ltd. | Liquid phase synthesis of peptides and peptide derivatives |
| IE921942A1 (en) * | 1992-06-16 | 1993-12-29 | Gary A Siwruk John S Eynon | Liquid phase synthesis of peptides and peptide derivatives |
| JP2003500415A (ja) * | 1999-05-26 | 2003-01-07 | アボット・ラボラトリーズ | イオン交換樹脂をスカベンジャーとして使用して単離処理を最も少なくしたペプチド合成方法 |
| IL150601A (en) | 2001-07-19 | 2010-06-30 | Organon Nv | Process for rapid synthesis of peptides within a solution using the back of an activated carboxyl component and destruction of the residual activated carboxyl component |
| WO2003018188A1 (fr) | 2001-08-24 | 2003-03-06 | Japan Science And Technology Agency | Systeme de solvant multiphase compatible |
| JP4283469B2 (ja) * | 2001-12-19 | 2009-06-24 | 独立行政法人科学技術振興機構 | 相溶性−多相有機溶媒システムによりアミノ酸を逐次的に付加する液相ペプチド合成法 |
| US7689649B2 (en) | 2002-05-31 | 2010-03-30 | Aol Inc. | Rendering destination instant messaging personalization items before communicating with destination |
| JP2004059509A (ja) * | 2002-07-30 | 2004-02-26 | Nokodai Tlo Kk | 液相ペプチド合成用アミノ酸試薬 |
| WO2006104166A1 (fr) | 2005-03-29 | 2006-10-05 | National University Corporation, Tokyo University Of Agriculture And Technology | Support pour separation par cristallisation et procede pour separer un compose |
| EP1927584B1 (fr) | 2005-09-20 | 2016-11-30 | Jitsubo Co., Ltd. | Support de séparation, procédé de séparation d un composé et procédé de synthèse de peptide utilisant le support |
| US8716439B2 (en) | 2006-03-01 | 2014-05-06 | Kaneka Corporation | Method of producing peptide |
| ES2546808T3 (es) * | 2006-03-24 | 2015-09-28 | Jitsubo Co., Ltd. | Reactivo para síntesis orgánica y método de reacción de síntesis orgánica con dicho reactivo |
| EP2415744A4 (fr) | 2009-03-12 | 2014-03-19 | Ajinomoto Kk | Composé fluorène |
| WO2010113939A1 (fr) | 2009-03-30 | 2010-10-07 | 味の素株式会社 | Composé diphénylméthane |
| WO2012165546A1 (fr) * | 2011-05-31 | 2012-12-06 | 味の素株式会社 | Procédé pour produire un peptide |
-
2016
- 2016-03-02 ES ES16758925T patent/ES2864924T3/es active Active
- 2016-03-02 EP EP16758925.8A patent/EP3266792B1/fr active Active
- 2016-03-02 DK DK16758925.8T patent/DK3266792T3/da active
- 2016-03-02 US US15/555,484 patent/US11098078B2/en active Active
- 2016-03-02 JP JP2017503668A patent/JP6713983B2/ja active Active
- 2016-03-02 WO PCT/JP2016/056319 patent/WO2016140232A1/fr active Application Filing
- 2016-03-02 CN CN201680013620.6A patent/CN107406480B/zh active Active
- 2016-03-03 TW TW105106523A patent/TW201639867A/zh unknown
Also Published As
| Publication number | Publication date |
|---|---|
| JPWO2016140232A1 (ja) | 2017-12-21 |
| EP3266792B1 (fr) | 2020-12-30 |
| US11098078B2 (en) | 2021-08-24 |
| WO2016140232A1 (fr) | 2016-09-09 |
| TW201639867A (zh) | 2016-11-16 |
| EP3266792A4 (fr) | 2018-05-09 |
| ES2864924T3 (es) | 2021-10-14 |
| CN107406480A (zh) | 2017-11-28 |
| JP6713983B2 (ja) | 2020-06-24 |
| CN107406480B (zh) | 2022-06-24 |
| EP3266792A1 (fr) | 2018-01-10 |
| US20180215782A1 (en) | 2018-08-02 |
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