DK3255062T3 - Anti-nkp46-antistof til diagnosticering af et ikke-kutant perifert t-cellelymfom (ptcl) - Google Patents
Anti-nkp46-antistof til diagnosticering af et ikke-kutant perifert t-cellelymfom (ptcl) Download PDFInfo
- Publication number
- DK3255062T3 DK3255062T3 DK17177583.6T DK17177583T DK3255062T3 DK 3255062 T3 DK3255062 T3 DK 3255062T3 DK 17177583 T DK17177583 T DK 17177583T DK 3255062 T3 DK3255062 T3 DK 3255062T3
- Authority
- DK
- Denmark
- Prior art keywords
- cutant
- diagnostication
- ptcl
- peripheral
- cell lymphoma
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/574—Immunoassay; Biospecific binding assay; Materials therefor for cancer
- G01N33/57484—Immunoassay; Biospecific binding assay; Materials therefor for cancer involving compounds serving as markers for tumor, cancer, neoplasia, e.g. cellular determinants, receptors, heat shock/stress proteins, A-protein, oligosaccharides, metabolites
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A61P35/02—Antineoplastic agents specific for leukemia
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
- C07K16/2803—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the immunoglobulin superfamily
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
- C07K16/30—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants from tumour cells
- C07K16/3061—Blood cells
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/574—Immunoassay; Biospecific binding assay; Materials therefor for cancer
- G01N33/57407—Specifically defined cancers
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
- C07K2317/73—Inducing cell death, e.g. apoptosis, necrosis or inhibition of cell proliferation
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
- C07K2317/73—Inducing cell death, e.g. apoptosis, necrosis or inhibition of cell proliferation
- C07K2317/732—Antibody-dependent cellular cytotoxicity [ADCC]
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
- G01N2333/435—Assays involving biological materials from specific organisms or of a specific nature from animals; from humans
- G01N2333/705—Assays involving receptors, cell surface antigens or cell surface determinants
- G01N2333/70503—Immunoglobulin superfamily, e.g. VCAMs, PECAM, LFA-3
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Immunology (AREA)
- Organic Chemistry (AREA)
- Molecular Biology (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Biochemistry (AREA)
- Hematology (AREA)
- Cell Biology (AREA)
- Engineering & Computer Science (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Genetics & Genomics (AREA)
- Biophysics (AREA)
- Biomedical Technology (AREA)
- Urology & Nephrology (AREA)
- Oncology (AREA)
- Food Science & Technology (AREA)
- Analytical Chemistry (AREA)
- Biotechnology (AREA)
- Microbiology (AREA)
- Pathology (AREA)
- General Physics & Mathematics (AREA)
- Hospice & Palliative Care (AREA)
- Physics & Mathematics (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Animal Behavior & Ethology (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Peptides Or Proteins (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US201361764639P | 2013-02-14 | 2013-02-14 | |
US201361831792P | 2013-06-06 | 2013-06-06 | |
EP14704576.9A EP2956482B1 (en) | 2013-02-14 | 2014-02-13 | Treatment of peripheral t cell lymphoma |
Publications (1)
Publication Number | Publication Date |
---|---|
DK3255062T3 true DK3255062T3 (da) | 2019-10-07 |
Family
ID=50112904
Family Applications (2)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DK14704576.9T DK2956482T3 (da) | 2013-02-14 | 2014-02-13 | Behandling af perifert t-cellelymfom |
DK17177583.6T DK3255062T3 (da) | 2013-02-14 | 2014-02-13 | Anti-nkp46-antistof til diagnosticering af et ikke-kutant perifert t-cellelymfom (ptcl) |
Family Applications Before (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DK14704576.9T DK2956482T3 (da) | 2013-02-14 | 2014-02-13 | Behandling af perifert t-cellelymfom |
Country Status (5)
Country | Link |
---|---|
US (2) | US10344087B2 (da) |
EP (2) | EP3255062B1 (da) |
DK (2) | DK2956482T3 (da) |
ES (2) | ES2747920T3 (da) |
WO (1) | WO2014125041A1 (da) |
Families Citing this family (10)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP3255062B1 (en) * | 2013-02-14 | 2019-07-03 | Innate Pharma | Anti-nkp46 antibody for diganosis of a non-cutaneous peripheral t-cell lymphoma (ptcl) |
WO2016030488A1 (en) * | 2014-08-27 | 2016-03-03 | Innate Pharma | Treatment of celiac disease |
CN107850596B (zh) | 2015-07-24 | 2020-12-04 | 先天制药公司 | 用于检测组织浸润nk细胞的方法 |
US11001629B2 (en) * | 2015-12-28 | 2021-05-11 | Innate Pharma | Variable regions for NKp46 binding proteins |
WO2018032088A2 (en) * | 2016-08-17 | 2018-02-22 | University Health Network | Regulation of tumor-associated t cells |
EP3510047A1 (en) | 2016-09-07 | 2019-07-17 | Yissum Research and Development Company of the Hebrew University of Jerusalem Ltd. | Anti-nkp46 antibodies and therapeutic use of same |
US20190248895A1 (en) | 2016-10-21 | 2019-08-15 | Innate Pharma | Treatment with anti-kir3dl2 agents |
US11377492B2 (en) * | 2017-01-24 | 2022-07-05 | Innate Pharma | NKp46 binding agents |
AU2018267695A1 (en) | 2017-05-19 | 2019-12-19 | Royal Melbourne Institute Of Technology | Predicting responders to cyclophosphamide therapy |
CA3099308A1 (en) | 2018-05-21 | 2019-11-28 | Compass Therapeutics Llc | Compositions and methods for enhancing the killing of target cells by nk cells |
Family Cites Families (40)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4816567A (en) | 1983-04-08 | 1989-03-28 | Genentech, Inc. | Recombinant immunoglobin preparations |
US5567610A (en) | 1986-09-04 | 1996-10-22 | Bioinvent International Ab | Method of producing human monoclonal antibodies and kit therefor |
US6673986B1 (en) | 1990-01-12 | 2004-01-06 | Abgenix, Inc. | Generation of xenogeneic antibodies |
US5229275A (en) | 1990-04-26 | 1993-07-20 | Akzo N.V. | In-vitro method for producing antigen-specific human monoclonal antibodies |
US5776427A (en) | 1992-03-05 | 1998-07-07 | Board Of Regents, The University Of Texas System | Methods for targeting the vasculature of solid tumors |
WO1997041898A1 (en) | 1996-05-03 | 1997-11-13 | Immunomedics, Inc. | Targeted combination immunotherapy of cancer |
US6277375B1 (en) | 1997-03-03 | 2001-08-21 | Board Of Regents, The University Of Texas System | Immunoglobulin-like domains with increased half-lives |
PT1071700E (pt) | 1998-04-20 | 2010-04-23 | Glycart Biotechnology Ag | Modificação por glicosilação de anticorpos para melhorar a citotoxicidade celular dependente de anticorpos |
US7183387B1 (en) | 1999-01-15 | 2007-02-27 | Genentech, Inc. | Polypeptide variants with altered effector function |
KR100940380B1 (ko) | 1999-01-15 | 2010-02-02 | 제넨테크, 인크. | 효과기 기능이 변화된 폴리펩티드 변이체 |
US6737056B1 (en) | 1999-01-15 | 2004-05-18 | Genentech, Inc. | Polypeptide variants with altered effector function |
ES2571230T3 (es) | 1999-04-09 | 2016-05-24 | Kyowa Hakko Kirin Co Ltd | Procedimiento para controlar la actividad de una molécula inmunofuncional |
AU2002337935B2 (en) | 2001-10-25 | 2008-05-01 | Genentech, Inc. | Glycoprotein compositions |
US20040132101A1 (en) | 2002-09-27 | 2004-07-08 | Xencor | Optimized Fc variants and methods for their generation |
CN102911987B (zh) | 2002-04-09 | 2015-09-30 | 协和发酵麒麟株式会社 | 基因组被修饰的细胞 |
CA2495251C (en) | 2002-08-14 | 2018-03-06 | Macrogenics, Inc. | Fc.gamma.riib-specific antibodies and methods of use thereof |
US20060235208A1 (en) * | 2002-09-27 | 2006-10-19 | Xencor, Inc. | Fc variants with optimized properties |
WO2004103269A2 (en) | 2002-10-18 | 2004-12-02 | Macrogenics, Inc. | Methods and compositions for vaccination comprising nucleic acid and/or polypeptide sequences of the genus borrelia |
US7355008B2 (en) | 2003-01-09 | 2008-04-08 | Macrogenics, Inc. | Identification and engineering of antibodies with variant Fc regions and methods of using same |
US7960512B2 (en) | 2003-01-09 | 2011-06-14 | Macrogenics, Inc. | Identification and engineering of antibodies with variant Fc regions and methods of using same |
DE10324108B3 (de) | 2003-05-21 | 2005-01-27 | Aesculap Ag & Co. Kg | Wirbelkörperersatzimplantat |
AU2004290070A1 (en) | 2003-11-12 | 2005-05-26 | Biogen Idec Ma Inc. | Neonatal Fc receptor (FcRn)-binding polypeptide variants, dimeric Fc binding proteins and methods related thereto |
MXPA06011796A (es) | 2004-04-16 | 2007-05-07 | Macrogenics Inc | Anticuerpos especificos de fc(riib y metodos para el uso de los mismos. |
KR101297146B1 (ko) | 2004-05-10 | 2013-08-21 | 마크로제닉스, 인크. | 인간화 FcγRIIB 특이적 항체 및 그의 사용 방법 |
WO2007024249A2 (en) | 2004-11-10 | 2007-03-01 | Macrogenics, Inc. | Engineering fc antibody regions to confer effector function |
AU2006255085A1 (en) | 2005-06-03 | 2006-12-14 | Genentech, Inc. | Method of producing antibodies with modified fucosylation level |
US8217147B2 (en) | 2005-08-10 | 2012-07-10 | Macrogenics, Inc. | Identification and engineering of antibodies with variant Fc regions and methods of using same |
US9447185B2 (en) * | 2005-10-14 | 2016-09-20 | Innate Pharma, S.A. | Compositions and methods for treating proliferative disorders |
AU2012202895A1 (en) | 2005-10-14 | 2012-06-07 | Innate Pharma | Compositions and methods for treating proliferative disorders |
FR2894982A1 (fr) | 2005-12-16 | 2007-06-22 | Lab Francais Du Fractionnement | Procede de preparation d'anticorps selectifs des recepteurs fc activateurs |
AU2007205935B2 (en) | 2006-01-17 | 2013-07-11 | Synthon Biopharmaceuticals B.V. | Compositions and methods for humanization and optimization of N-glycans in plants |
EP1999470A4 (en) | 2006-03-10 | 2009-08-19 | Macrogenics Inc | IDENTIFICATION AND GENETIC MODIFICATION OF ANTIBODIES WITH HEAVY CHAINS OF VARIANTS AND METHODS OF USE THEREOF |
WO2008105886A2 (en) | 2006-05-26 | 2008-09-04 | Macrogenics, Inc. | HUMANIZED FCγRIIB-SPECIFIC ANTIBODIES AND METHODS OF USE THEREOF |
EP2032159B1 (en) | 2006-06-26 | 2015-01-07 | MacroGenics, Inc. | Combination of fcgammariib antibodies and cd20-specific antibodies and methods of use thereof |
EP1878747A1 (en) | 2006-07-11 | 2008-01-16 | greenovation Biotech GmbH | Glyco-engineered antibodies |
EP1995309A1 (en) | 2007-05-21 | 2008-11-26 | Vivalis | Recombinant protein production in avian EBx® cells |
WO2011086179A1 (en) * | 2010-01-15 | 2011-07-21 | INSERM (Institut National de la Santé et de la Recherche Médicale) | Methods for diagnosis and treatment of cutaneous t cell lymphomas |
NZ602161A (en) | 2010-03-04 | 2014-12-24 | Macrogenics Inc | Antibodies reactive with b7-h3, immunologically active fragments thereof and uses thereof |
EP2723362A1 (en) | 2011-06-21 | 2014-04-30 | Innate Pharma | NKp46-MEDIATED NK CELL TUNING |
EP3255062B1 (en) * | 2013-02-14 | 2019-07-03 | Innate Pharma | Anti-nkp46 antibody for diganosis of a non-cutaneous peripheral t-cell lymphoma (ptcl) |
-
2014
- 2014-02-13 EP EP17177583.6A patent/EP3255062B1/en active Active
- 2014-02-13 ES ES17177583T patent/ES2747920T3/es active Active
- 2014-02-13 DK DK14704576.9T patent/DK2956482T3/da active
- 2014-02-13 ES ES14704576.9T patent/ES2637151T3/es active Active
- 2014-02-13 DK DK17177583.6T patent/DK3255062T3/da active
- 2014-02-13 US US14/767,600 patent/US10344087B2/en active Active
- 2014-02-13 WO PCT/EP2014/052849 patent/WO2014125041A1/en active Application Filing
- 2014-02-13 EP EP14704576.9A patent/EP2956482B1/en active Active
-
2019
- 2019-06-25 US US16/451,051 patent/US11999784B2/en active Active
Also Published As
Publication number | Publication date |
---|---|
EP2956482A1 (en) | 2015-12-23 |
DK2956482T3 (da) | 2017-10-16 |
US10344087B2 (en) | 2019-07-09 |
EP2956482B1 (en) | 2017-06-28 |
ES2637151T3 (es) | 2017-10-11 |
US11999784B2 (en) | 2024-06-04 |
EP3255062B1 (en) | 2019-07-03 |
US20190315857A1 (en) | 2019-10-17 |
WO2014125041A1 (en) | 2014-08-21 |
EP3255062A1 (en) | 2017-12-13 |
ES2747920T3 (es) | 2020-03-12 |
US20150376274A1 (en) | 2015-12-31 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
DK3255062T3 (da) | Anti-nkp46-antistof til diagnosticering af et ikke-kutant perifert t-cellelymfom (ptcl) | |
DK3071223T3 (da) | Cell | |
DK3043816T3 (da) | Anti-b7-h1-antistoffer til behandling af tumorer | |
DK3336106T3 (da) | Anti-fcrh5-antistoffer | |
DK2992020T3 (da) | Cs1-specifik kimær antigenreceptor-manipulerede immuneffektorceller | |
DK3042411T3 (da) | Metalunderstøttet fastoxidbrændselscelle | |
DK3572105T3 (da) | Injektionsindretning til terapeutisk middel | |
DK3537097T3 (da) | Indretning til udformning af riller i rørelementer | |
DK3017520T3 (da) | Solcelleanordning | |
DK2953972T3 (da) | Fremgangsmåde til udvælgelse af antistoffer mod bcma | |
DK3003075T3 (da) | Kit til inhalering af fordampede substanser | |
DK2968415T3 (da) | Cd123-specifik kimær antigenreceptor-omdirigerede t-celler og fremgangsmåder til anvendelse deraf | |
DK3447942T3 (da) | Bølgedelingsmultiplexer-anordning til små cellenetværk | |
DK2989057T3 (da) | Elektrokemisk filterapparat | |
DK3454346T3 (da) | Anordning til cylotronfremstilling af technetium-99m | |
DK3708583T3 (da) | Ikke-fucosylerede anti-fgfr2iiib-antistoffer | |
DK3005199T3 (da) | Paradigme-medikament respons netværk | |
DK3913511T3 (da) | Mobilenhedsetui til generering af brugerdata | |
FR3003076B1 (fr) | Supercondensateur electrochimique | |
DK3680000T3 (da) | Fremgangsmåder til oprensning af antistoffer | |
DK2843320T3 (da) | Modulbærer | |
KR20180084767A (ko) | 휴대폰 하우징 적용을 위한 폴리카보네이트-폴리실록산 공중합체 조성물 | |
DK3003456T3 (da) | Indretning til anvendelse af flydende lægemidler | |
DK3068800T3 (da) | FcRn-specifikke antistoffer | |
DK3071247T3 (da) | Indretning til konstruktion af hud |