DK3224621T3 - Nærhedsanalyser under anvendelse af kemisk ligering og haptenoverførsel - Google Patents
Nærhedsanalyser under anvendelse af kemisk ligering og haptenoverførsel Download PDFInfo
- Publication number
- DK3224621T3 DK3224621T3 DK15798449.3T DK15798449T DK3224621T3 DK 3224621 T3 DK3224621 T3 DK 3224621T3 DK 15798449 T DK15798449 T DK 15798449T DK 3224621 T3 DK3224621 T3 DK 3224621T3
- Authority
- DK
- Denmark
- Prior art keywords
- hapten
- analyzes
- proximity
- transfer
- chemical ligation
- Prior art date
Links
Classifications
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
- G01N33/6803—General methods of protein analysis not limited to specific proteins or families of proteins
- G01N33/6845—Methods of identifying protein-protein interactions in protein mixtures
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/536—Immunoassay; Biospecific binding assay; Materials therefor with immune complex formed in liquid phase
- G01N33/542—Immunoassay; Biospecific binding assay; Materials therefor with immune complex formed in liquid phase with steric inhibition or signal modification, e.g. fluorescent quenching
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/543—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/543—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
- G01N33/54353—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals with ligand attached to the carrier via a chemical coupling agent
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/574—Immunoassay; Biospecific binding assay; Materials therefor for cancer
- G01N33/57484—Immunoassay; Biospecific binding assay; Materials therefor for cancer involving compounds serving as markers for tumor, cancer, neoplasia, e.g. cellular determinants, receptors, heat shock/stress proteins, A-protein, oligosaccharides, metabolites
- G01N33/57492—Immunoassay; Biospecific binding assay; Materials therefor for cancer involving compounds serving as markers for tumor, cancer, neoplasia, e.g. cellular determinants, receptors, heat shock/stress proteins, A-protein, oligosaccharides, metabolites involving compounds localized on the membrane of tumor or cancer cells
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2440/00—Post-translational modifications [PTMs] in chemical analysis of biological material
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Immunology (AREA)
- Engineering & Computer Science (AREA)
- Molecular Biology (AREA)
- Biomedical Technology (AREA)
- Chemical & Material Sciences (AREA)
- Hematology (AREA)
- Urology & Nephrology (AREA)
- Physics & Mathematics (AREA)
- Cell Biology (AREA)
- General Physics & Mathematics (AREA)
- Pathology (AREA)
- Medicinal Chemistry (AREA)
- Biotechnology (AREA)
- Analytical Chemistry (AREA)
- Biochemistry (AREA)
- General Health & Medical Sciences (AREA)
- Microbiology (AREA)
- Food Science & Technology (AREA)
- Bioinformatics & Computational Biology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Biophysics (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Oncology (AREA)
- Hospice & Palliative Care (AREA)
- Peptides Or Proteins (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Investigating Or Analysing Biological Materials (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201462084452P | 2014-11-25 | 2014-11-25 | |
| US201562116962P | 2015-02-17 | 2015-02-17 | |
| PCT/EP2015/077484 WO2016083364A1 (en) | 2014-11-25 | 2015-11-24 | Proximity assays using chemical ligation and hapten transfer |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| DK3224621T3 true DK3224621T3 (da) | 2019-08-12 |
Family
ID=54697581
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DK15798449.3T DK3224621T3 (da) | 2014-11-25 | 2015-11-24 | Nærhedsanalyser under anvendelse af kemisk ligering og haptenoverførsel |
Country Status (8)
| Country | Link |
|---|---|
| US (3) | US10620217B2 (cg-RX-API-DMAC7.html) |
| EP (1) | EP3224621B1 (cg-RX-API-DMAC7.html) |
| JP (1) | JP6909156B2 (cg-RX-API-DMAC7.html) |
| CN (1) | CN107003323B (cg-RX-API-DMAC7.html) |
| AU (1) | AU2015352625B2 (cg-RX-API-DMAC7.html) |
| CA (1) | CA2965872C (cg-RX-API-DMAC7.html) |
| DK (1) | DK3224621T3 (cg-RX-API-DMAC7.html) |
| WO (1) | WO2016083364A1 (cg-RX-API-DMAC7.html) |
Families Citing this family (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP3341734B1 (en) | 2015-08-28 | 2024-08-07 | Ventana Medical Systems, Inc. | Protein proximity assay in formalin fixed paffafin embedded tissue using caged haptens |
| WO2018118786A1 (en) * | 2016-12-19 | 2018-06-28 | Ventana Medical Systems, Inc. | Methods and systems for quantitative immunohistochemistry |
| GB2562721A (en) * | 2017-05-16 | 2018-11-28 | Fastbase Solutions Ltd | Kits, methods and their uses for detecting cell-cell interactions in a sample |
| WO2019200326A1 (en) | 2018-04-13 | 2019-10-17 | Rarecyte, Inc. | Kits for labeling of biomarkers and methods of using the same |
| WO2019241191A1 (en) | 2018-06-11 | 2019-12-19 | Merck Sharp & Dohme Corp. | Cut vertex method for identifying complex molecule substructures |
| US12385923B2 (en) | 2018-11-15 | 2025-08-12 | Arizona Board Of Regents On Behalf Of Arizona State University | Cleavable fluorescent tyramide for sensitive and multiplexed analysis of biological samples |
| CN116868054A (zh) * | 2021-01-25 | 2023-10-10 | 文塔纳医疗系统公司 | 包括用一个或多个可检测部分标记的一种或多种生物标志物的染色生物学样本 |
| CN113552362B (zh) * | 2021-07-23 | 2024-08-09 | 湖北百奥斯生物科技有限公司 | 一种新型信号放大的免疫荧光试剂盒 |
| WO2023058624A1 (ja) * | 2021-10-08 | 2023-04-13 | コニカミノルタ株式会社 | 染色方法、評価方法および標本 |
Family Cites Families (21)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4711955A (en) | 1981-04-17 | 1987-12-08 | Yale University | Modified nucleotides and methods of preparing and using same |
| US5266684A (en) | 1988-05-02 | 1993-11-30 | The Reagents Of The University Of California | Peptide mixtures |
| CH683667A5 (fr) | 1992-02-26 | 1994-04-29 | Nestle Sa | Matière première aromatique. |
| US5654419A (en) | 1994-02-01 | 1997-08-05 | The Regents Of The University Of California | Fluorescent labels and their use in separations |
| ATE214396T1 (de) | 1995-06-21 | 2002-03-15 | Martek Biosciences Corp | Kombinatorische bibliotheken aus markierten biochemischen verbindungen und verfahren zu ihrer herstellung |
| US5661028A (en) | 1995-09-29 | 1997-08-26 | Lockheed Martin Energy Systems, Inc. | Large scale DNA microsequencing device |
| US6444421B1 (en) * | 1997-11-19 | 2002-09-03 | The United States Of America As Represented By The Department Of Health And Human Services | Methods for detecting intermolecular interactions in vivo and in vitro |
| WO2005037071A2 (en) * | 2003-10-14 | 2005-04-28 | Monogram Biosciences, Inc. | Receptor tyrosine kinase signaling pathway analysis for diagnosis and therapy |
| US20060246523A1 (en) | 2005-04-28 | 2006-11-02 | Christopher Bieniarz | Antibody conjugates |
| JP2008541015A (ja) | 2005-04-28 | 2008-11-20 | ベンタナ・メデイカル・システムズ・インコーポレーテツド | ナノ粒子コンジュゲート |
| WO2007062177A2 (en) | 2005-11-23 | 2007-05-31 | Ventana Medical Systems, Inc. | Molecular conjugate |
| CA3069091C (en) | 2006-11-01 | 2021-09-14 | Ventana Medical Systems, Inc. | Haptens, hapten conjugates, compositions thereof and method for their preparation and use |
| EP2109689A4 (en) * | 2007-02-07 | 2010-02-10 | Perscitus Biosciences Llc | DETECTION OF THE PROXIMITY OF A MOLECULE |
| RU2476891C2 (ru) | 2007-09-04 | 2013-02-27 | Санофи-Авентис | Идентификация молекул, модулирующих белок-белковое взаимодействие |
| ES2526519T3 (es) * | 2009-01-15 | 2015-01-13 | Laboratory Corporation Of America Holdings | Métodos de determinación de la respuesta del paciente por medición de la expresión HER-2 |
| CN101620233B (zh) * | 2009-05-27 | 2012-10-31 | 华中科技大学 | 一种蛋白质相互作用的检测方法 |
| AU2010278710A1 (en) | 2009-07-31 | 2012-03-15 | Prognosys Biosciences, Inc. | Assay tools and methods of use |
| GB0918712D0 (en) | 2009-10-26 | 2009-12-09 | Axis Shield Diagnostics Ltd | An assay |
| CA2867144C (en) | 2012-03-27 | 2019-07-02 | Ventana Medical Systems, Inc. | Signaling conjugates and methods of use |
| AU2014230945B2 (en) * | 2013-03-12 | 2019-07-11 | Ventana Medical Systems, Inc. | Proximity assay for in situ detection of targets |
| CN103245789B (zh) * | 2013-04-27 | 2014-10-29 | 深圳先进技术研究院 | 用于肿瘤病理诊断的试剂盒及对组织切片进行染色的方法 |
-
2015
- 2015-11-24 CA CA2965872A patent/CA2965872C/en active Active
- 2015-11-24 AU AU2015352625A patent/AU2015352625B2/en active Active
- 2015-11-24 DK DK15798449.3T patent/DK3224621T3/da active
- 2015-11-24 EP EP15798449.3A patent/EP3224621B1/en active Active
- 2015-11-24 JP JP2017527719A patent/JP6909156B2/ja active Active
- 2015-11-24 CN CN201580063800.0A patent/CN107003323B/zh active Active
- 2015-11-24 WO PCT/EP2015/077484 patent/WO2016083364A1/en not_active Ceased
-
2017
- 2017-05-23 US US15/603,079 patent/US10620217B2/en active Active
-
2020
- 2020-03-04 US US16/809,290 patent/US11808770B2/en active Active
-
2023
- 2023-09-27 US US18/373,328 patent/US20240069034A1/en active Pending
Also Published As
| Publication number | Publication date |
|---|---|
| CA2965872C (en) | 2022-02-22 |
| AU2015352625B2 (en) | 2019-07-25 |
| JP2017536548A (ja) | 2017-12-07 |
| AU2015352625A1 (en) | 2017-04-20 |
| CN107003323A (zh) | 2017-08-01 |
| CN107003323B (zh) | 2019-06-04 |
| WO2016083364A1 (en) | 2016-06-02 |
| US20240069034A1 (en) | 2024-02-29 |
| US10620217B2 (en) | 2020-04-14 |
| CA2965872A1 (en) | 2016-06-02 |
| US20170254813A1 (en) | 2017-09-07 |
| JP6909156B2 (ja) | 2021-07-28 |
| EP3224621A1 (en) | 2017-10-04 |
| US20200271662A1 (en) | 2020-08-27 |
| US11808770B2 (en) | 2023-11-07 |
| EP3224621B1 (en) | 2019-06-12 |
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