DK322385A - Fremgangsmaade til fremstilling af alkaloider - Google Patents
Fremgangsmaade til fremstilling af alkaloider Download PDFInfo
- Publication number
- DK322385A DK322385A DK322385A DK322385A DK322385A DK 322385 A DK322385 A DK 322385A DK 322385 A DK322385 A DK 322385A DK 322385 A DK322385 A DK 322385A DK 322385 A DK322385 A DK 322385A
- Authority
- DK
- Denmark
- Prior art keywords
- group
- hydrogen atom
- carbon atoms
- benzoyloxy
- acyloxy
- Prior art date
Links
- 238000000034 method Methods 0.000 title abstract 3
- 238000002360 preparation method Methods 0.000 title abstract 2
- 229930013930 alkaloid Natural products 0.000 title 1
- 125000004435 hydrogen atom Chemical group [H]* 0.000 abstract 8
- 125000004432 carbon atom Chemical group C* 0.000 abstract 6
- 125000004423 acyloxy group Chemical group 0.000 abstract 5
- 125000001231 benzoyloxy group Chemical group C(C1=CC=CC=C1)(=O)O* 0.000 abstract 5
- 125000002887 hydroxy group Chemical group [H]O* 0.000 abstract 4
- 125000000217 alkyl group Chemical group 0.000 abstract 3
- VEXZGXHMUGYJMC-UHFFFAOYSA-N Hydrochloric acid Chemical compound Cl VEXZGXHMUGYJMC-UHFFFAOYSA-N 0.000 abstract 2
- YGYAWVDWMABLBF-UHFFFAOYSA-N Phosgene Chemical compound ClC(Cl)=O YGYAWVDWMABLBF-UHFFFAOYSA-N 0.000 abstract 2
- 125000000852 azido group Chemical group *N=[N+]=[N-] 0.000 abstract 2
- 238000006243 chemical reaction Methods 0.000 abstract 2
- HCUYBXPSSCRKRF-UHFFFAOYSA-N diphosgene Chemical compound ClC(=O)OC(Cl)(Cl)Cl HCUYBXPSSCRKRF-UHFFFAOYSA-N 0.000 abstract 2
- 125000005843 halogen group Chemical group 0.000 abstract 2
- WSLDOOZREJYCGB-UHFFFAOYSA-N 1,2-Dichloroethane Chemical compound ClCCCl WSLDOOZREJYCGB-UHFFFAOYSA-N 0.000 abstract 1
- 239000002253 acid Substances 0.000 abstract 1
- 125000002252 acyl group Chemical group 0.000 abstract 1
- 229910052783 alkali metal Inorganic materials 0.000 abstract 1
- 229910000288 alkali metal carbonate Inorganic materials 0.000 abstract 1
- 150000008041 alkali metal carbonates Chemical class 0.000 abstract 1
- -1 alkali metal hydrogen carbonates Chemical class 0.000 abstract 1
- 125000003710 aryl alkyl group Chemical group 0.000 abstract 1
- 125000003118 aryl group Chemical group 0.000 abstract 1
- 125000003236 benzoyl group Chemical group [H]C1=C([H])C([H])=C(C([H])=C1[H])C(*)=O 0.000 abstract 1
- 150000001875 compounds Chemical class 0.000 abstract 1
- 230000007062 hydrolysis Effects 0.000 abstract 1
- 238000006460 hydrolysis reaction Methods 0.000 abstract 1
- 229910052500 inorganic mineral Inorganic materials 0.000 abstract 1
- 238000002955 isolation Methods 0.000 abstract 1
- 239000011707 mineral Substances 0.000 abstract 1
- 150000003810 morphinanes Chemical class 0.000 abstract 1
- 125000004430 oxygen atom Chemical group O* 0.000 abstract 1
- 239000002904 solvent Substances 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D489/00—Heterocyclic compounds containing 4aH-8, 9 c- Iminoethano-phenanthro [4, 5-b, c, d] furan ring systems, e.g. derivatives of [4, 5-epoxy]-morphinan of the formula:
- C07D489/02—Heterocyclic compounds containing 4aH-8, 9 c- Iminoethano-phenanthro [4, 5-b, c, d] furan ring systems, e.g. derivatives of [4, 5-epoxy]-morphinan of the formula: with oxygen atoms attached in positions 3 and 6, e.g. morphine, morphinone
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D489/00—Heterocyclic compounds containing 4aH-8, 9 c- Iminoethano-phenanthro [4, 5-b, c, d] furan ring systems, e.g. derivatives of [4, 5-epoxy]-morphinan of the formula:
- C07D489/06—Heterocyclic compounds containing 4aH-8, 9 c- Iminoethano-phenanthro [4, 5-b, c, d] furan ring systems, e.g. derivatives of [4, 5-epoxy]-morphinan of the formula: with a hetero atom directly attached in position 14
- C07D489/08—Oxygen atom
Landscapes
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
- Ultra Sonic Daignosis Equipment (AREA)
- Measurement And Recording Of Electrical Phenomena And Electrical Characteristics Of The Living Body (AREA)
- Finger-Pressure Massage (AREA)
- Stringed Musical Instruments (AREA)
- Electrophonic Musical Instruments (AREA)
- Polyesters Or Polycarbonates (AREA)
- Materials For Photolithography (AREA)
- Other In-Based Heterocyclic Compounds (AREA)
- Polysaccharides And Polysaccharide Derivatives (AREA)
- Other Investigation Or Analysis Of Materials By Electrical Means (AREA)
- Cephalosporin Compounds (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| HU842774A HU197750B (en) | 1984-07-17 | 1984-07-17 | Process for n-demethylation of morphine alkaloids |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| DK322385D0 DK322385D0 (da) | 1985-07-15 |
| DK322385A true DK322385A (da) | 1986-01-18 |
Family
ID=10961043
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DK322385A DK322385A (da) | 1984-07-17 | 1985-07-15 | Fremgangsmaade til fremstilling af alkaloider |
Country Status (18)
| Country | Link |
|---|---|
| EP (1) | EP0168686B1 (OSRAM) |
| JP (1) | JPS6193184A (OSRAM) |
| AT (1) | ATE41933T1 (OSRAM) |
| BG (1) | BG44029A3 (OSRAM) |
| CS (1) | CS251792B2 (OSRAM) |
| DD (1) | DD235639A5 (OSRAM) |
| DE (1) | DE3569244D1 (OSRAM) |
| DK (1) | DK322385A (OSRAM) |
| ES (1) | ES8603716A1 (OSRAM) |
| FI (1) | FI81583C (OSRAM) |
| HU (1) | HU197750B (OSRAM) |
| IL (2) | IL75509A0 (OSRAM) |
| IN (1) | IN166255B (OSRAM) |
| NO (1) | NO161915C (OSRAM) |
| PL (1) | PL254552A1 (OSRAM) |
| RO (1) | RO91516B (OSRAM) |
| SU (1) | SU1398776A3 (OSRAM) |
| YU (1) | YU45264B (OSRAM) |
Families Citing this family (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101896463B (zh) * | 2007-12-17 | 2016-08-24 | 马林克罗特有限公司 | 制备(+)阿片类的方法和化合物 |
| EP2222643B1 (en) * | 2007-12-17 | 2019-03-20 | SpecGx LLC | Sinomenine derivatives and processes for their synthesis |
| DE112010001980T8 (de) * | 2009-05-12 | 2012-11-08 | Board Of Regents, The University Of Texas System | Synthese von Morphin und verwandten Derivaten |
| PL2593095T3 (pl) * | 2010-07-16 | 2019-12-31 | Mallinckrodt Llc | (+)-morfinany jako antagoniści receptora toll-podobnego 9 i ich terapeutyczne zastosowania |
| PL2753622T3 (pl) | 2011-09-08 | 2016-07-29 | SpecGx LLC | Wytwarzanie alkaloidów bez oddzielania związków pośrednich |
Family Cites Families (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CA948198A (en) * | 1967-08-04 | 1974-05-28 | Gerhard Walther | Production of cyclic amino compounds |
| DE2254298A1 (de) * | 1972-11-06 | 1974-05-16 | Boehringer Sohn Ingelheim | Neue (heteroarylmethyl)-normorphine, deren saeureadditionssalze, verfahren zu deren herstellung sowie deren verwendung als arzneimittel |
| DE2727805A1 (de) * | 1977-06-21 | 1979-01-04 | Goedecke Ag | Verfahren zur herstellung von oxynormorphon |
-
1984
- 1984-07-17 HU HU842774A patent/HU197750B/hu not_active IP Right Cessation
-
1985
- 1985-06-13 IL IL75509A patent/IL75509A0/xx not_active IP Right Cessation
- 1985-06-14 IN IN476/DEL/85A patent/IN166255B/en unknown
- 1985-06-20 ES ES544385A patent/ES8603716A1/es not_active Expired
- 1985-06-26 AT AT85107895T patent/ATE41933T1/de not_active IP Right Cessation
- 1985-06-26 EP EP85107895A patent/EP0168686B1/de not_active Expired
- 1985-06-26 DE DE8585107895T patent/DE3569244D1/de not_active Expired
- 1985-07-12 DD DD85278546A patent/DD235639A5/de not_active IP Right Cessation
- 1985-07-15 FI FI852779A patent/FI81583C/fi not_active IP Right Cessation
- 1985-07-15 PL PL25455285A patent/PL254552A1/xx unknown
- 1985-07-15 RO RO119568A patent/RO91516B/ro unknown
- 1985-07-15 BG BG071084A patent/BG44029A3/xx unknown
- 1985-07-15 DK DK322385A patent/DK322385A/da not_active Application Discontinuation
- 1985-07-16 JP JP60156846A patent/JPS6193184A/ja active Pending
- 1985-07-16 CS CS855280A patent/CS251792B2/cs unknown
- 1985-07-16 NO NO852838A patent/NO161915C/no unknown
- 1985-07-16 SU SU853923700A patent/SU1398776A3/ru active
- 1985-07-17 YU YU1174/85A patent/YU45264B/xx unknown
-
1986
- 1986-04-15 IL IL78503A patent/IL78503A/xx not_active IP Right Cessation
Also Published As
| Publication number | Publication date |
|---|---|
| FI81583C (fi) | 1990-11-12 |
| CS251792B2 (en) | 1987-08-13 |
| HUT38645A (en) | 1986-06-30 |
| DD235639A5 (de) | 1986-05-14 |
| YU117485A (en) | 1988-04-30 |
| RO91516A (ro) | 1987-06-30 |
| EP0168686B1 (de) | 1989-04-05 |
| IL78503A (en) | 1990-01-18 |
| SU1398776A3 (ru) | 1988-06-15 |
| HU197750B (en) | 1989-05-29 |
| DK322385D0 (da) | 1985-07-15 |
| FI852779L (fi) | 1986-01-18 |
| ES8603716A1 (es) | 1986-01-16 |
| DE3569244D1 (en) | 1989-05-11 |
| YU45264B (en) | 1992-05-28 |
| IN166255B (OSRAM) | 1990-03-31 |
| IL75509A0 (en) | 1985-10-31 |
| FI81583B (fi) | 1990-07-31 |
| FI852779A0 (fi) | 1985-07-15 |
| EP0168686A1 (de) | 1986-01-22 |
| PL254552A1 (en) | 1986-07-15 |
| NO161915B (no) | 1989-07-03 |
| JPS6193184A (ja) | 1986-05-12 |
| ES544385A0 (es) | 1986-01-16 |
| NO852838L (no) | 1986-01-20 |
| BG44029A3 (en) | 1988-09-15 |
| CS528085A2 (en) | 1986-12-18 |
| NO161915C (no) | 1989-10-11 |
| RO91516B (ro) | 1987-07-01 |
| ATE41933T1 (de) | 1989-04-15 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| AHS | Application shelved for other reasons than non-payment |