DK3212733T3 - Nye kromofore strukturer til makrocykliske lanthanidchelater - Google Patents

Nye kromofore strukturer til makrocykliske lanthanidchelater Download PDF

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Publication number
DK3212733T3
DK3212733T3 DK15790066T DK15790066T DK3212733T3 DK 3212733 T3 DK3212733 T3 DK 3212733T3 DK 15790066 T DK15790066 T DK 15790066T DK 15790066 T DK15790066 T DK 15790066T DK 3212733 T3 DK3212733 T3 DK 3212733T3
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Prior art keywords
lanthanide chelates
macrocyclic lanthanide
chromophoric structures
new
new chromophoric
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Application number
DK15790066T
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English (en)
Inventor
Harri Takalo
Henri Sund
Original Assignee
Radiometer Turku Oy
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Publication of DK3212733T3 publication Critical patent/DK3212733T3/da

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    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D401/00Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/14Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing three or more hetero rings
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K16/00Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • CCHEMISTRY; METALLURGY
    • C09DYES; PAINTS; POLISHES; NATURAL RESINS; ADHESIVES; COMPOSITIONS NOT OTHERWISE PROVIDED FOR; APPLICATIONS OF MATERIALS NOT OTHERWISE PROVIDED FOR
    • C09KMATERIALS FOR MISCELLANEOUS APPLICATIONS, NOT PROVIDED FOR ELSEWHERE
    • C09K11/00Luminescent, e.g. electroluminescent, chemiluminescent materials
    • C09K11/06Luminescent, e.g. electroluminescent, chemiluminescent materials containing organic luminescent materials
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/531Production of immunochemical test materials
    • G01N33/532Production of labelled immunochemicals
    • G01N33/533Production of labelled immunochemicals with fluorescent label
    • CCHEMISTRY; METALLURGY
    • C09DYES; PAINTS; POLISHES; NATURAL RESINS; ADHESIVES; COMPOSITIONS NOT OTHERWISE PROVIDED FOR; APPLICATIONS OF MATERIALS NOT OTHERWISE PROVIDED FOR
    • C09KMATERIALS FOR MISCELLANEOUS APPLICATIONS, NOT PROVIDED FOR ELSEWHERE
    • C09K2211/00Chemical nature of organic luminescent or tenebrescent compounds
    • C09K2211/10Non-macromolecular compounds
    • C09K2211/1003Carbocyclic compounds
    • C09K2211/1007Non-condensed systems
    • CCHEMISTRY; METALLURGY
    • C09DYES; PAINTS; POLISHES; NATURAL RESINS; ADHESIVES; COMPOSITIONS NOT OTHERWISE PROVIDED FOR; APPLICATIONS OF MATERIALS NOT OTHERWISE PROVIDED FOR
    • C09KMATERIALS FOR MISCELLANEOUS APPLICATIONS, NOT PROVIDED FOR ELSEWHERE
    • C09K2211/00Chemical nature of organic luminescent or tenebrescent compounds
    • C09K2211/10Non-macromolecular compounds
    • C09K2211/1018Heterocyclic compounds
    • C09K2211/1025Heterocyclic compounds characterised by ligands
    • C09K2211/1029Heterocyclic compounds characterised by ligands containing one nitrogen atom as the heteroatom
    • CCHEMISTRY; METALLURGY
    • C09DYES; PAINTS; POLISHES; NATURAL RESINS; ADHESIVES; COMPOSITIONS NOT OTHERWISE PROVIDED FOR; APPLICATIONS OF MATERIALS NOT OTHERWISE PROVIDED FOR
    • C09KMATERIALS FOR MISCELLANEOUS APPLICATIONS, NOT PROVIDED FOR ELSEWHERE
    • C09K2211/00Chemical nature of organic luminescent or tenebrescent compounds
    • C09K2211/10Non-macromolecular compounds
    • C09K2211/1018Heterocyclic compounds
    • C09K2211/1025Heterocyclic compounds characterised by ligands
    • C09K2211/1059Heterocyclic compounds characterised by ligands containing three nitrogen atoms as heteroatoms
    • CCHEMISTRY; METALLURGY
    • C09DYES; PAINTS; POLISHES; NATURAL RESINS; ADHESIVES; COMPOSITIONS NOT OTHERWISE PROVIDED FOR; APPLICATIONS OF MATERIALS NOT OTHERWISE PROVIDED FOR
    • C09KMATERIALS FOR MISCELLANEOUS APPLICATIONS, NOT PROVIDED FOR ELSEWHERE
    • C09K2211/00Chemical nature of organic luminescent or tenebrescent compounds
    • C09K2211/18Metal complexes
    • C09K2211/182Metal complexes of the rare earth metals, i.e. Sc, Y or lanthanide
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2458/00Labels used in chemical analysis of biological material
    • G01N2458/40Rare earth chelates

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  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Immunology (AREA)
  • Engineering & Computer Science (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Molecular Biology (AREA)
  • Materials Engineering (AREA)
  • Hematology (AREA)
  • Biomedical Technology (AREA)
  • Biochemistry (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Urology & Nephrology (AREA)
  • Physics & Mathematics (AREA)
  • Biotechnology (AREA)
  • Genetics & Genomics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Microbiology (AREA)
  • Food Science & Technology (AREA)
  • Biophysics (AREA)
  • Analytical Chemistry (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Cell Biology (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Investigating Or Analysing Materials By The Use Of Chemical Reactions (AREA)
DK15790066T 2014-10-29 2015-10-27 Nye kromofore strukturer til makrocykliske lanthanidchelater DK3212733T3 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DKPA201400627 2014-10-29
PCT/EP2015/074867 WO2016066641A1 (en) 2014-10-29 2015-10-27 New chromophoric structures for macrocyclic lanthanide chelates

Publications (1)

Publication Number Publication Date
DK3212733T3 true DK3212733T3 (da) 2019-11-04

Family

ID=54396851

Family Applications (1)

Application Number Title Priority Date Filing Date
DK15790066T DK3212733T3 (da) 2014-10-29 2015-10-27 Nye kromofore strukturer til makrocykliske lanthanidchelater

Country Status (7)

Country Link
US (2) US20170313936A1 (da)
EP (1) EP3212733B1 (da)
JP (1) JP6480579B2 (da)
CN (1) CN107074815B (da)
DK (1) DK3212733T3 (da)
PL (1) PL3212733T3 (da)
WO (1) WO2016066641A1 (da)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP6924780B2 (ja) 2016-06-09 2021-08-25 ラジオメーター・トゥルク・オサケユキチュア 結合アッセイのバックグラウンド遮断剤
FR3067349B1 (fr) * 2017-06-12 2020-12-04 Cisbio Bioassays Nouveaux agents mono et di-antennes complexants hydrosolubles et complexes de lanthanide correspondants
JP2022540001A (ja) * 2019-06-25 2022-09-14 ラジオメーター・トゥルク・オサケユキチュア 新規発光ランタニドキレートレポーター、新規発光ランタニドキレートレポーターで標識された生体特異的結合反応物、及びそれらの使用

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2978149B1 (fr) * 2011-07-18 2014-01-10 Cisbio Bioassays Nouveaux agents complexants et complexes de lanthanide correspondant, et leur utilisation comme marqueurs luminescents
JP5818990B2 (ja) * 2011-08-19 2015-11-18 デーホーアェル・フィンランド・オサケユキチュア 3つの発色団を有する発光ランタニドキレート及びそれらの使用
CN104125997B (zh) * 2011-12-22 2017-03-08 雷度米特图尔库公司 具有提升的激发性质的新型发光镧系元素螯合物
FR3000960B1 (fr) * 2013-01-16 2015-03-06 Cisbio Bioassays Nouveaux agents complexants hydrosolubles et complexes de lanthanide correspondants
WO2014147288A1 (en) * 2013-01-31 2014-09-25 Kaivogen Oy Luminescent triazacyclononane-based lanthanide chelate complexes as labelling reagents

Also Published As

Publication number Publication date
US20210395606A1 (en) 2021-12-23
EP3212733B1 (en) 2019-08-28
EP3212733A1 (en) 2017-09-06
JP2017533209A (ja) 2017-11-09
PL3212733T3 (pl) 2020-02-28
JP6480579B2 (ja) 2019-03-13
CN107074815A (zh) 2017-08-18
US20170313936A1 (en) 2017-11-02
CN107074815B (zh) 2021-06-22
WO2016066641A1 (en) 2016-05-06

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