DK3199951T3 - Arginin-vasopressin-prohormon som prædiktiv biomarkør for diabetes - Google Patents
Arginin-vasopressin-prohormon som prædiktiv biomarkør for diabetes Download PDFInfo
- Publication number
- DK3199951T3 DK3199951T3 DK16205552.9T DK16205552T DK3199951T3 DK 3199951 T3 DK3199951 T3 DK 3199951T3 DK 16205552 T DK16205552 T DK 16205552T DK 3199951 T3 DK3199951 T3 DK 3199951T3
- Authority
- DK
- Denmark
- Prior art keywords
- prohormon
- biomarket
- vasopressin
- predictive
- arginine
- Prior art date
Links
- 101800001144 Arg-vasopressin Proteins 0.000 title 1
- 102100026383 Vasopressin-neurophysin 2-copeptin Human genes 0.000 title 1
- KBZOIRJILGZLEJ-LGYYRGKSSA-N argipressin Chemical compound C([C@H]1C(=O)N[C@@H](CCC(N)=O)C(=O)N[C@@H](CC(N)=O)C(=O)N[C@@H](CSSC[C@@H](C(N[C@@H](CC=2C=CC(O)=CC=2)C(=O)N1)=O)N)C(=O)N1[C@@H](CCC1)C(=O)N[C@@H](CCCN=C(N)N)C(=O)NCC(N)=O)C1=CC=CC=C1 KBZOIRJILGZLEJ-LGYYRGKSSA-N 0.000 title 1
- 206010012601 diabetes mellitus Diseases 0.000 title 1
Classifications
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/04—Anorexiants; Antiobesity agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/06—Antihyperlipidemics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/12—Antihypertensives
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
- C07K7/04—Linear peptides containing only normal peptide links
- C07K7/16—Oxytocins; Vasopressins; Related peptides
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/577—Immunoassay; Biospecific binding assay; Materials therefor involving monoclonal antibodies binding reaction mechanisms characterised by the use of monoclonal antibodies; monoclonal antibodies per se are classified with their corresponding antigens
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/74—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving hormones or other non-cytokine intercellular protein regulatory factors such as growth factors, including receptors to hormones and growth factors
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2410/00—Assays, e.g. immunoassays or enzyme assays, involving peptides of less than 20 animo acids
- G01N2410/04—Oxytocins; Vasopressins; Related peptides
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2800/00—Detection or diagnosis of diseases
- G01N2800/04—Endocrine or metabolic disorders
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2800/00—Detection or diagnosis of diseases
- G01N2800/04—Endocrine or metabolic disorders
- G01N2800/042—Disorders of carbohydrate metabolism, e.g. diabetes, glucose metabolism
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Molecular Biology (AREA)
- Hematology (AREA)
- Immunology (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Urology & Nephrology (AREA)
- Biomedical Technology (AREA)
- Organic Chemistry (AREA)
- Biochemistry (AREA)
- Biotechnology (AREA)
- General Physics & Mathematics (AREA)
- Food Science & Technology (AREA)
- Analytical Chemistry (AREA)
- Pathology (AREA)
- Microbiology (AREA)
- Cell Biology (AREA)
- Physics & Mathematics (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Public Health (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Diabetes (AREA)
- Pharmacology & Pharmacy (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Veterinary Medicine (AREA)
- Animal Behavior & Ethology (AREA)
- General Chemical & Material Sciences (AREA)
- Endocrinology (AREA)
- Biophysics (AREA)
- Genetics & Genomics (AREA)
- Obesity (AREA)
- Emergency Medicine (AREA)
- Child & Adolescent Psychology (AREA)
- Heart & Thoracic Surgery (AREA)
- Cardiology (AREA)
- Investigating Or Analysing Biological Materials (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP08168096 | 2008-10-31 | ||
| EP09744978.9A EP2356463B1 (en) | 2008-10-31 | 2009-10-29 | Arginine vasopressin pro-hormone as predictive biomarker for diabetes |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| DK3199951T3 true DK3199951T3 (da) | 2020-02-24 |
Family
ID=40445457
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DK16205552.9T DK3199951T3 (da) | 2008-10-31 | 2009-10-29 | Arginin-vasopressin-prohormon som prædiktiv biomarkør for diabetes |
Country Status (7)
| Country | Link |
|---|---|
| US (2) | US9116153B2 (enExample) |
| EP (2) | EP3199951B1 (enExample) |
| JP (2) | JP5785086B2 (enExample) |
| CN (3) | CN102317788A (enExample) |
| DK (1) | DK3199951T3 (enExample) |
| ES (2) | ES2645688T3 (enExample) |
| WO (1) | WO2010049179A1 (enExample) |
Families Citing this family (13)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE10316583A1 (de) * | 2003-04-10 | 2004-10-28 | B.R.A.H.M.S Aktiengesellschaft | Bestimmung eines midregionalen Proadrenomedullin-Teilpeptids in biologischen Flüssigkeiten zu diagnostischen Zwecken, sowie Immunoassays für die Durchführung einer solchen Bestimmung |
| US7838250B1 (en) | 2006-04-04 | 2010-11-23 | Singulex, Inc. | Highly sensitive system and methods for analysis of troponin |
| EP2016394A4 (en) | 2006-04-04 | 2013-04-24 | Singulex Inc | METHOD AND COMPOSITIONS FOR HIGHLY SENSITIVE ANALYSIS OF MARKERS AND DETECTION OF MOLECULES |
| DE102006060112A1 (de) * | 2006-12-20 | 2008-06-26 | Brahms Aktiengesellschaft | Diagnose und Risikostratifizierung mittels dem neuen Marker CT-proADM |
| AU2010259022B2 (en) | 2009-06-08 | 2016-05-12 | Singulex, Inc. | Highly sensitive biomarker panels |
| US20130149386A1 (en) * | 2011-12-07 | 2013-06-13 | Region Nordjylland | Cd36 as biomarker for steatosis |
| US20130338027A1 (en) * | 2012-06-15 | 2013-12-19 | Nuclea Biotechnologies, Inc. | Predictive Markers For Cancer and Metabolic Syndrome |
| JP6196034B2 (ja) | 2012-12-20 | 2017-09-13 | ライオン株式会社 | 高血糖リスク判定用マーカーペプチドおよびその用途 |
| CN103266089A (zh) * | 2013-05-09 | 2013-08-28 | 南京医科大学第一附属医院 | 抗人和肽素单克隆抗体mcco1及其应用 |
| US20160097781A1 (en) * | 2014-10-01 | 2016-04-07 | Sphingotec Gmbh | Method for stratifying a female subject for hormone replacement therapy |
| CA3134929A1 (en) * | 2019-03-28 | 2020-10-01 | Lundoch Diagnostics AB | Use of follistatin in type 2 diabetes risk prediction |
| CN113238063A (zh) * | 2021-05-31 | 2021-08-10 | 迈克生物股份有限公司 | Gdf15评估代谢综合征患者进展为心血管疾病的应用 |
| CN113248590B (zh) * | 2021-06-24 | 2021-09-10 | 天津奇云诺德生物医学有限公司 | 一种NT-proBNP蛋白抗原决定簇多肽及其应用 |
Family Cites Families (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB9606016D0 (en) * | 1996-03-22 | 1996-05-22 | Smithkline Beecham Plc | Novel use |
| DE60335387D1 (de) * | 2002-07-16 | 2011-01-27 | Woomera Therapeutics Inc | Zusammensetzungen und deren verwendungen zur identifizierung und zum targetting von provasopressinexprimierenden krebszellen |
| EP1673465A4 (en) * | 2003-09-29 | 2008-04-30 | Biosite Inc | PROCESS AND COMPOSITIONS FOR SEPSIS DIAGNOSIS |
| EP1628136A1 (en) * | 2004-08-19 | 2006-02-22 | B.R.A.H.M.S. Aktiengesellschaft | Method of diagnosis of disease using copeptin |
| US20070218519A1 (en) * | 2005-10-11 | 2007-09-20 | Tethys Bioscience, Inc. | Diabetes-associated markers and methods of use thereof |
| JP5855332B2 (ja) * | 2006-10-18 | 2016-02-09 | アクセラ インコーポレーテッド | 広い濃度範囲にわたる複数アナライトの光回折による測定 |
| JP5320294B2 (ja) * | 2006-10-26 | 2013-10-23 | ベー．エル．アー．ハー．エム．エス ゲーエムベーハー | プロバソプレシンまたはその断片および部分ペプチド、特にコペプチンまたはニューロフィジンｉｉを使用する、急性冠動脈症候群についてのリスク層化 |
| WO2008128352A1 (en) * | 2007-04-19 | 2008-10-30 | Axela, Inc. | Methods and compositions for signal amplification |
-
2009
- 2009-10-29 JP JP2011533626A patent/JP5785086B2/ja active Active
- 2009-10-29 EP EP16205552.9A patent/EP3199951B1/en active Active
- 2009-10-29 CN CN2009801438824A patent/CN102317788A/zh active Pending
- 2009-10-29 CN CN201610269547.0A patent/CN106153943B/zh active Active
- 2009-10-29 CN CN201310681318.6A patent/CN103713137A/zh active Pending
- 2009-10-29 ES ES09744978.9T patent/ES2645688T3/es active Active
- 2009-10-29 DK DK16205552.9T patent/DK3199951T3/da active
- 2009-10-29 ES ES16205552T patent/ES2772930T3/es active Active
- 2009-10-29 WO PCT/EP2009/007923 patent/WO2010049179A1/en not_active Ceased
- 2009-10-29 US US13/126,798 patent/US9116153B2/en active Active
- 2009-10-29 EP EP09744978.9A patent/EP2356463B1/en active Active
-
2015
- 2015-03-04 JP JP2015042777A patent/JP6055005B2/ja active Active
- 2015-06-25 US US14/750,201 patent/US9952229B2/en active Active
Also Published As
| Publication number | Publication date |
|---|---|
| JP2015135338A (ja) | 2015-07-27 |
| WO2010049179A1 (en) | 2010-05-06 |
| CN103713137A (zh) | 2014-04-09 |
| CN106153943B (zh) | 2019-02-15 |
| CN102317788A (zh) | 2012-01-11 |
| ES2772930T3 (es) | 2020-07-08 |
| US9952229B2 (en) | 2018-04-24 |
| JP5785086B2 (ja) | 2015-09-24 |
| CN106153943A (zh) | 2016-11-23 |
| JP6055005B2 (ja) | 2016-12-27 |
| US20150293127A1 (en) | 2015-10-15 |
| US20110318766A1 (en) | 2011-12-29 |
| EP2356463A1 (en) | 2011-08-17 |
| JP2012507020A (ja) | 2012-03-22 |
| ES2645688T3 (es) | 2017-12-07 |
| EP2356463B1 (en) | 2017-08-30 |
| EP3199951B1 (en) | 2019-11-20 |
| US9116153B2 (en) | 2015-08-25 |
| EP3199951A1 (en) | 2017-08-02 |
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