DK3130602T3 - Immunregulerende strukturer fra normalt forekommende proteiner - Google Patents

Immunregulerende strukturer fra normalt forekommende proteiner Download PDF

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Publication number
DK3130602T3
DK3130602T3 DK16189090T DK16189090T DK3130602T3 DK 3130602 T3 DK3130602 T3 DK 3130602T3 DK 16189090 T DK16189090 T DK 16189090T DK 16189090 T DK16189090 T DK 16189090T DK 3130602 T3 DK3130602 T3 DK 3130602T3
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Denmark
Prior art keywords
normally present
immune regulatory
present proteins
regulatory structures
structures
Prior art date
Application number
DK16189090T
Other languages
English (en)
Inventor
Leif Hakansson
Birgitta Clinchy
Original Assignee
Canimguide Therapeutics Ab
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Application filed by Canimguide Therapeutics Ab filed Critical Canimguide Therapeutics Ab
Application granted granted Critical
Publication of DK3130602T3 publication Critical patent/DK3130602T3/da

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    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K16/00Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • A61P37/02Immunomodulators
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • A61P37/02Immunomodulators
    • A61P37/06Immunosuppressants, e.g. drugs for graft rejection
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/76Albumins
    • C07K14/765Serum albumin, e.g. HSA
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/5005Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells
    • G01N33/5008Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics
    • G01N33/5044Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics involving specific cell types
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/574Immunoassay; Biospecific binding assay; Materials therefor for cancer
    • G01N33/57484Immunoassay; Biospecific binding assay; Materials therefor for cancer involving compounds serving as markers for tumor, cancer, neoplasia, e.g. cellular determinants, receptors, heat shock/stress proteins, A-protein, oligosaccharides, metabolites
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/505Medicinal preparations containing antigens or antibodies comprising antibodies
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/30Immunoglobulins specific features characterized by aspects of specificity or valency
    • C07K2317/34Identification of a linear epitope shorter than 20 amino acid residues or of a conformational epitope defined by amino acid residues
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2333/00Assays involving biological materials from specific organisms or of a specific nature
    • G01N2333/435Assays involving biological materials from specific organisms or of a specific nature from animals; from humans
    • G01N2333/52Assays involving cytokines
    • G01N2333/54Interleukins [IL]
    • G01N2333/55IL-2
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2333/00Assays involving biological materials from specific organisms or of a specific nature
    • G01N2333/435Assays involving biological materials from specific organisms or of a specific nature from animals; from humans
    • G01N2333/76Assays involving albumins other than in routine use for blocking surfaces or for anchoring haptens during immunisation
    • G01N2333/765Serum albumin, e.g. HSA
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2500/00Screening for compounds of potential therapeutic value
    • G01N2500/10Screening for compounds of potential therapeutic value involving cells

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Immunology (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • Biomedical Technology (AREA)
  • Cell Biology (AREA)
  • Urology & Nephrology (AREA)
  • Hematology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Toxicology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Veterinary Medicine (AREA)
  • General Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Biotechnology (AREA)
  • General Physics & Mathematics (AREA)
  • Microbiology (AREA)
  • Analytical Chemistry (AREA)
  • Food Science & Technology (AREA)
  • Zoology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Hospice & Palliative Care (AREA)
  • Oncology (AREA)
  • Transplantation (AREA)
  • Peptides Or Proteins (AREA)
DK16189090T 2007-05-08 2008-05-08 Immunregulerende strukturer fra normalt forekommende proteiner DK3130602T3 (da)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
SE0701099 2007-05-08
SE0701100 2007-05-08
SE0702520 2007-11-15
EP12164229.2A EP2487186B1 (en) 2007-05-08 2008-05-08 Immunoregulatory structures from normally occuring proteins

Publications (1)

Publication Number Publication Date
DK3130602T3 true DK3130602T3 (da) 2019-11-04

Family

ID=39709034

Family Applications (2)

Application Number Title Priority Date Filing Date
DK12164229.2T DK2487186T3 (da) 2007-05-08 2008-05-08 Immunregulatoriske strukturer fra normalt forekommende proteiner
DK16189090T DK3130602T3 (da) 2007-05-08 2008-05-08 Immunregulerende strukturer fra normalt forekommende proteiner

Family Applications Before (1)

Application Number Title Priority Date Filing Date
DK12164229.2T DK2487186T3 (da) 2007-05-08 2008-05-08 Immunregulatoriske strukturer fra normalt forekommende proteiner

Country Status (5)

Country Link
US (4) US9120874B2 (da)
EP (4) EP3636667A3 (da)
DK (2) DK2487186T3 (da)
ES (2) ES2747363T3 (da)
WO (1) WO2008136736A2 (da)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1507548B1 (en) * 2002-05-27 2014-10-01 CanImGuide Therapeutics AB Method for determining immune system affecting compounds
SE0402536D0 (sv) 2004-10-20 2004-10-20 Therim Diagnostica Ab Immunoregulation in cancer, chronic inflammatory and autoimmune diseases
EP1875246B1 (en) 2005-04-15 2016-10-05 CanImGuide Therapeutics AB Diagnostic method for detecting cancer by measuring amount of a cytokine like il-6
WO2008136736A2 (en) 2007-05-08 2008-11-13 Canimguide Therapeutics Ab Immunoregulatory structures from normally occurring proteins
US8455624B2 (en) * 2011-06-03 2013-06-04 University Of South Alabama Methods and compositions for detecting endometrial or ovarian cancer
CN111732652A (zh) * 2013-09-09 2020-10-02 卡尼姆盖德治疗学公司 免疫系统调节器
CN103694342B (zh) * 2013-11-12 2015-11-25 北京理工大学 检测人老龄化的多肽标志物
WO2016131962A1 (en) * 2015-02-20 2016-08-25 Pharis Biotec Gmbh Polypeptide with activity against diphtheria toxin
CA2978617A1 (en) * 2015-03-06 2016-09-15 Canimguide Therapeutics Ab Immune system modulators and compositions
CN112789030A (zh) 2018-09-28 2021-05-11 卡尼姆盖德治疗学公司 肽抑制剂的药物制剂
CN109294998B (zh) * 2018-09-30 2020-11-06 北京鼎成肽源生物技术有限公司 一种rff1细胞
CN109294982B (zh) * 2018-09-30 2020-11-06 北京鼎成肽源生物技术有限公司 一种rff2细胞
CN111499746B (zh) * 2020-04-28 2020-11-24 优睿赛思(武汉)生物科技有限公司 一种针对人白介素-2的高亲和力兔单克隆抗体及其应用

Family Cites Families (21)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS6216430A (ja) 1985-07-12 1987-01-24 Ajinomoto Co Inc インタ−ロイキン2レセプタ−発現誘導物質a
DE378732T1 (de) 1989-01-20 1991-05-02 Aziende Chimiche Riunite Angelini Francesco A.C.R.A.F. S.P.A., Rom/Roma, It Serum-proteine in bezug auf autoimmunerkrankungen.
CA2015515C (en) 1990-01-03 1999-12-07 Jean-Marie Saint-Remy Pharmaceutical compositions containing antigen-antibody complexes and uses therefor
US6737057B1 (en) 1997-01-07 2004-05-18 The University Of Tennessee Research Corporation Compounds, compositions and methods for the endocytic presentation of immunosuppressive factors
US5948609A (en) * 1997-12-03 1999-09-07 Carter; Daniel C. Oxygen-transporting albumin-based blood replacement composition and blood volume expander
AU1243500A (en) 1998-11-06 2000-05-29 Emory University Biomarkers for oxidative stress
EP1326892A2 (en) 2000-10-12 2003-07-16 University of Rochester Compositions that inhibit proliferation of cancer cells
AU2002312410A1 (en) 2001-06-08 2002-12-23 Target Protein Technologies, Inc. Tissue-specific endothelial membrane proteins
EP1507548B1 (en) 2002-05-27 2014-10-01 CanImGuide Therapeutics AB Method for determining immune system affecting compounds
AU2003298689A1 (en) 2002-11-21 2004-06-18 Wyeth Methods for diagnosing rcc and other solid tumors
WO2004082617A2 (en) * 2003-03-14 2004-09-30 Ppd Biomarker Discovery Sciences, Llc Biological markers for diagnosing rheumatoid arthritis
JP4068538B2 (ja) 2003-09-12 2008-03-26 株式会社サン・クロレラ サイトカイン遊離阻害剤
SE0402536D0 (sv) 2004-10-20 2004-10-20 Therim Diagnostica Ab Immunoregulation in cancer, chronic inflammatory and autoimmune diseases
KR100664587B1 (ko) 2004-12-22 2007-01-04 김현기 인간 암 억제 유전자, 이에 의해 코딩되는 단백질, 이를포함하는 발현 벡터 및 이 벡터로 형질전환된 세포
EP1875246B1 (en) 2005-04-15 2016-10-05 CanImGuide Therapeutics AB Diagnostic method for detecting cancer by measuring amount of a cytokine like il-6
US8232066B2 (en) 2006-07-03 2012-07-31 The Johns Hopkins University Peptide antibody depletion and its application to mass spectrometry sample preparation
WO2008136736A2 (en) 2007-05-08 2008-11-13 Canimguide Therapeutics Ab Immunoregulatory structures from normally occurring proteins
RU2360924C1 (ru) 2007-12-21 2009-07-10 Институт биохимии им. А.А. Баха РАН Маркер рака предстательной железы
US8455624B2 (en) 2011-06-03 2013-06-04 University Of South Alabama Methods and compositions for detecting endometrial or ovarian cancer
CN111732652A (zh) 2013-09-09 2020-10-02 卡尼姆盖德治疗学公司 免疫系统调节器
CN103694342B (zh) 2013-11-12 2015-11-25 北京理工大学 检测人老龄化的多肽标志物

Also Published As

Publication number Publication date
US9120874B2 (en) 2015-09-01
WO2008136736A8 (en) 2009-07-23
ES2747363T3 (es) 2020-03-10
ES2608803T3 (es) 2017-04-17
WO2008136736A2 (en) 2008-11-13
DK2487186T3 (da) 2017-01-16
EP2226334A3 (en) 2010-12-29
EP2226334A2 (en) 2010-09-08
EP3636667A2 (en) 2020-04-15
US9796777B2 (en) 2017-10-24
US20160046702A1 (en) 2016-02-18
EP3130602B1 (en) 2019-08-07
EP3130602A1 (en) 2017-02-15
EP2487186A1 (en) 2012-08-15
US20110262470A1 (en) 2011-10-27
US20180030126A1 (en) 2018-02-01
EP2487186B1 (en) 2016-09-28
EP3636667A3 (en) 2020-07-29
US20200048331A1 (en) 2020-02-13
WO2008136736A3 (en) 2009-02-26

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