DK2487186T3 - Immunregulatoriske strukturer fra normalt forekommende proteiner - Google Patents

Immunregulatoriske strukturer fra normalt forekommende proteiner Download PDF

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Publication number
DK2487186T3
DK2487186T3 DK12164229.2T DK12164229T DK2487186T3 DK 2487186 T3 DK2487186 T3 DK 2487186T3 DK 12164229 T DK12164229 T DK 12164229T DK 2487186 T3 DK2487186 T3 DK 2487186T3
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DK
Denmark
Prior art keywords
occurring proteins
normally occurring
immune regulatory
regulatory structures
structures
Prior art date
Application number
DK12164229.2T
Other languages
English (en)
Inventor
Leif Hakansson
Birgitta Clinchy
Original Assignee
Canimguide Therapeutics Ab
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Canimguide Therapeutics Ab filed Critical Canimguide Therapeutics Ab
Application granted granted Critical
Publication of DK2487186T3 publication Critical patent/DK2487186T3/da

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/76—Albumins
    • C07K14/765—Serum albumin, e.g. HSA
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/5005—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells
    • G01N33/5008—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics
    • G01N33/5044—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics involving specific cell types
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/574—Immunoassay; Biospecific binding assay; Materials therefor for cancer
    • G01N33/57484—Immunoassay; Biospecific binding assay; Materials therefor for cancer involving compounds serving as markers for tumor, cancer, neoplasia, e.g. cellular determinants, receptors, heat shock/stress proteins, A-protein, oligosaccharides, metabolites
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/505—Medicinal preparations containing antigens or antibodies comprising antibodies
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/30—Immunoglobulins specific features characterized by aspects of specificity or valency
    • C07K2317/34—Identification of a linear epitope shorter than 20 amino acid residues or of a conformational epitope defined by amino acid residues
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
    • G01N2333/435—Assays involving biological materials from specific organisms or of a specific nature from animals; from humans
    • G01N2333/52—Assays involving cytokines
    • G01N2333/54—Interleukins [IL]
    • G01N2333/55—IL-2
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
    • G01N2333/435—Assays involving biological materials from specific organisms or of a specific nature from animals; from humans
    • G01N2333/76—Assays involving albumins other than in routine use for blocking surfaces or for anchoring haptens during immunisation
    • G01N2333/765—Serum albumin, e.g. HSA
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2500/00—Screening for compounds of potential therapeutic value
    • G01N2500/10—Screening for compounds of potential therapeutic value involving cells

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Immunology (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • Biomedical Technology (AREA)
  • Urology & Nephrology (AREA)
  • Hematology (AREA)
  • Cell Biology (AREA)
  • Biophysics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Genetics & Genomics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Toxicology (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Veterinary Medicine (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Analytical Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • General Physics & Mathematics (AREA)
  • Biotechnology (AREA)
  • Food Science & Technology (AREA)
  • Microbiology (AREA)
  • Pathology (AREA)
  • Zoology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Oncology (AREA)
  • Hospice & Palliative Care (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Transplantation (AREA)
  • Peptides Or Proteins (AREA)
DK12164229.2T 2007-05-08 2008-05-08 Immunregulatoriske strukturer fra normalt forekommende proteiner DK2487186T3 (da)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
SE0701100 2007-05-08
SE0701099 2007-05-08
SE0702520 2007-11-15
EP09178421A EP2226334A3 (en) 2007-05-08 2008-05-08 Immunoregulatory structures from normally occuring proteins

Publications (1)

Publication Number Publication Date
DK2487186T3 true DK2487186T3 (da) 2017-01-16

Family

ID=39709034

Family Applications (2)

Application Number Title Priority Date Filing Date
DK12164229.2T DK2487186T3 (da) 2007-05-08 2008-05-08 Immunregulatoriske strukturer fra normalt forekommende proteiner
DK16189090T DK3130602T3 (da) 2007-05-08 2008-05-08 Immunregulerende strukturer fra normalt forekommende proteiner

Family Applications After (1)

Application Number Title Priority Date Filing Date
DK16189090T DK3130602T3 (da) 2007-05-08 2008-05-08 Immunregulerende strukturer fra normalt forekommende proteiner

Country Status (5)

Country Link
US (4) US9120874B2 (da)
EP (4) EP3636667A3 (da)
DK (2) DK2487186T3 (da)
ES (2) ES2747363T3 (da)
WO (1) WO2008136736A2 (da)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2526950C (en) 2002-05-27 2012-06-26 Leif Hakansson Method for determining immune system affecting compounds
SE0402536D0 (sv) 2004-10-20 2004-10-20 Therim Diagnostica Ab Immunoregulation in cancer, chronic inflammatory and autoimmune diseases
WO2006110091A1 (en) 2005-04-15 2006-10-19 Therim Diagnostica Ab Diagnostic method for detecting cancer by measuring amount of a cytokine like il-6
WO2008136736A2 (en) 2007-05-08 2008-11-13 Canimguide Therapeutics Ab Immunoregulatory structures from normally occurring proteins
US8455624B2 (en) * 2011-06-03 2013-06-04 University Of South Alabama Methods and compositions for detecting endometrial or ovarian cancer
US9657059B2 (en) * 2013-09-09 2017-05-23 Canimguide Therapeutics Ab Immune system modulators
CN103694342B (zh) * 2013-11-12 2015-11-25 北京理工大学 检测人老龄化的多肽标志物
WO2016131962A1 (en) * 2015-02-20 2016-08-25 Pharis Biotec Gmbh Polypeptide with activity against diphtheria toxin
ES2853582T3 (es) 2015-03-06 2021-09-16 Canimguide Therapeutics Ab Moduladores del sistema inmune y composiciones
EP3856144A1 (en) 2018-09-28 2021-08-04 CanImGuide Therapeutics AB Pharmaceutical formulations of peptide inhibitors
CN109294998B (zh) * 2018-09-30 2020-11-06 北京鼎成肽源生物技术有限公司 一种rff1细胞
CN109294982B (zh) * 2018-09-30 2020-11-06 北京鼎成肽源生物技术有限公司 一种rff2细胞
CN111499746B (zh) * 2020-04-28 2020-11-24 优睿赛思(武汉)生物科技有限公司 一种针对人白介素-2的高亲和力兔单克隆抗体及其应用

Family Cites Families (21)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS6216430A (ja) 1985-07-12 1987-01-24 Ajinomoto Co Inc インタ−ロイキン２レセプタ−発現誘導物質ａ
EP0585960A3 (en) 1989-01-20 1994-03-16 AZIENDE CHIMICHE RIUNITE ANGELINI FRANCESCO A.C.R.A.F. S.p.A. Diagnostic method for autoimmune diseases
CA2015515C (en) 1990-01-03 1999-12-07 Jean-Marie Saint-Remy Pharmaceutical compositions containing antigen-antibody complexes and uses therefor
US6737057B1 (en) 1997-01-07 2004-05-18 The University Of Tennessee Research Corporation Compounds, compositions and methods for the endocytic presentation of immunosuppressive factors
US5948609A (en) * 1997-12-03 1999-09-07 Carter; Daniel C. Oxygen-transporting albumin-based blood replacement composition and blood volume expander
AU1243500A (en) 1998-11-06 2000-05-29 Emory University Biomarkers for oxidative stress
CA2425779C (en) 2000-10-12 2013-08-06 University Of Rochester Compositions that inhibit proliferation of cancer cells
EP1399215A4 (en) 2001-06-08 2004-12-22 Utah Ventures Ii L P TISSUE-SPECIFIC ENDOTHELM MEMBRANE PROTEINS
CA2526950C (en) * 2002-05-27 2012-06-26 Leif Hakansson Method for determining immune system affecting compounds
US7611839B2 (en) 2002-11-21 2009-11-03 Wyeth Methods for diagnosing RCC and other solid tumors
CA2527916A1 (en) * 2003-03-14 2004-09-30 Aaron B. Kantor Biological markers for diagnosing rheumatoid arthritis
JP4068538B2 (ja) 2003-09-12 2008-03-26 株式会社サン・クロレラ サイトカイン遊離阻害剤
SE0402536D0 (sv) 2004-10-20 2004-10-20 Therim Diagnostica Ab Immunoregulation in cancer, chronic inflammatory and autoimmune diseases
KR100664587B1 (ko) * 2004-12-22 2007-01-04 김현기 인간 암 억제 유전자, 이에 의해 코딩되는 단백질, 이를포함하는 발현 벡터 및 이 벡터로 형질전환된 세포
WO2006110091A1 (en) 2005-04-15 2006-10-19 Therim Diagnostica Ab Diagnostic method for detecting cancer by measuring amount of a cytokine like il-6
EP2044443B1 (en) 2006-07-03 2011-01-12 The Johns Hopkins University Peptide antibody depletion and its application to mass spectrometry sample preparation
WO2008136736A2 (en) 2007-05-08 2008-11-13 Canimguide Therapeutics Ab Immunoregulatory structures from normally occurring proteins
RU2360924C1 (ru) 2007-12-21 2009-07-10 Институт биохимии им. А.А. Баха РАН Маркер рака предстательной железы
US8455624B2 (en) 2011-06-03 2013-06-04 University Of South Alabama Methods and compositions for detecting endometrial or ovarian cancer
US9657059B2 (en) 2013-09-09 2017-05-23 Canimguide Therapeutics Ab Immune system modulators
CN103694342B (zh) 2013-11-12 2015-11-25 北京理工大学 检测人老龄化的多肽标志物

Also Published As

Publication number Publication date
ES2608803T3 (es) 2017-04-17
EP2487186B1 (en) 2016-09-28
US20180030126A1 (en) 2018-02-01
US9796777B2 (en) 2017-10-24
EP2226334A3 (en) 2010-12-29
DK3130602T3 (da) 2019-11-04
EP3130602B1 (en) 2019-08-07
WO2008136736A8 (en) 2009-07-23
EP2487186A1 (en) 2012-08-15
ES2747363T3 (es) 2020-03-10
EP2226334A2 (en) 2010-09-08
WO2008136736A2 (en) 2008-11-13
WO2008136736A3 (en) 2009-02-26
US20110262470A1 (en) 2011-10-27
US20200048331A1 (en) 2020-02-13
US9120874B2 (en) 2015-09-01
EP3636667A2 (en) 2020-04-15
US20160046702A1 (en) 2016-02-18
EP3130602A1 (en) 2017-02-15
EP3636667A3 (en) 2020-07-29

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