DK3072896T3 - Taxanforbindelse og fremgangsmåde til fremstilling heraf og dennes anvendelse - Google Patents

Taxanforbindelse og fremgangsmåde til fremstilling heraf og dennes anvendelse Download PDF

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Publication number
DK3072896T3
DK3072896T3 DK14863167.4T DK14863167T DK3072896T3 DK 3072896 T3 DK3072896 T3 DK 3072896T3 DK 14863167 T DK14863167 T DK 14863167T DK 3072896 T3 DK3072896 T3 DK 3072896T3
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Prior art keywords
procedure
manufacture
application
tax connection
tax
Prior art date
Application number
DK14863167.4T
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English (en)
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DK3072896T5 (da
Inventor
Wei Zhou
Yunrong Jing
Yongfeng Wang
Guocheng Wang
Original Assignee
Jiangsu Tasly Diyi Pharmaceutical Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
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Application filed by Jiangsu Tasly Diyi Pharmaceutical Co Ltd filed Critical Jiangsu Tasly Diyi Pharmaceutical Co Ltd
Publication of DK3072896T3 publication Critical patent/DK3072896T3/da
Application granted granted Critical
Publication of DK3072896T5 publication Critical patent/DK3072896T5/da

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Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D493/00Heterocyclic compounds containing oxygen atoms as the only ring hetero atoms in the condensed system
    • C07D493/02Heterocyclic compounds containing oxygen atoms as the only ring hetero atoms in the condensed system in which the condensed system contains two hetero rings
    • C07D493/08Bridged systems
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/335Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
    • A61K31/337Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having four-membered rings, e.g. taxol
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/335Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
    • A61K31/365Lactones
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/4427Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems
    • A61K31/443Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems containing a five-membered ring with oxygen as a ring hetero atom
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • A61P35/02Antineoplastic agents specific for leukemia

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  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Hematology (AREA)
  • Oncology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Epoxy Compounds (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
DK14863167.4T 2013-11-22 2014-11-21 Taxanforbindelse og fremgangsmåde til fremstilling heraf og dennes anvendelse DK3072896T5 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
CN201310594994.XA CN104650109B (zh) 2013-11-22 2013-11-22 紫杉烷类化合物
PCT/CN2014/091911 WO2015074606A1 (zh) 2013-11-22 2014-11-21 紫杉烷类化合物、其制备方法和用途

Publications (2)

Publication Number Publication Date
DK3072896T3 true DK3072896T3 (da) 2021-04-06
DK3072896T5 DK3072896T5 (da) 2021-05-31

Family

ID=53178985

Family Applications (1)

Application Number Title Priority Date Filing Date
DK14863167.4T DK3072896T5 (da) 2013-11-22 2014-11-21 Taxanforbindelse og fremgangsmåde til fremstilling heraf og dennes anvendelse

Country Status (11)

Country Link
US (1) US9890175B2 (da)
EP (1) EP3072896B1 (da)
JP (1) JP6573900B2 (da)
KR (1) KR20160087899A (da)
CN (1) CN104650109B (da)
AU (1) AU2014352372B2 (da)
CA (1) CA2931366C (da)
DK (1) DK3072896T5 (da)
RU (1) RU2686459C1 (da)
WO (1) WO2015074606A1 (da)
ZA (1) ZA201603990B (da)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN107056767B (zh) * 2015-12-04 2022-07-15 江苏恩华络康药物研发有限公司 用于制备水溶性紫杉烷类衍生物的方法及中间体
CN110143934B (zh) * 2018-08-29 2023-03-28 牡丹江师范学院 一种含氟紫杉烷类化合物及其制备方法与应用
CN110590793A (zh) * 2019-08-30 2019-12-20 浙江工业大学 一种2,4-二苯基吡啶并[3,2-c]香豆素的合成方法

Family Cites Families (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2698363B1 (fr) * 1992-11-23 1994-12-30 Rhone Poulenc Rorer Sa Nouveaux dérivés du taxane, leur préparation et les compositions qui les contiennent.
US5475011A (en) * 1993-03-26 1995-12-12 The Research Foundation Of State University Of New York Anti-tumor compounds, pharmaceutical compositions, methods for preparation thereof and for treatment
IT1275435B (it) * 1995-05-19 1997-08-07 Indena Spa Derivati della 10-desacetil-14beta-idrossibaccatina iii,loro metodo di preparazione e formulazioni che li contengono
EP0747372A1 (en) * 1995-06-06 1996-12-11 Dr. Reddy's Research Foundation Taxane derivatives from 14-beta-hydroxy-10 deacetybaccatin III
ITMI991483A1 (it) * 1999-07-06 2001-01-06 Indena Spa Derivati tassanici e procedimenti per la loro preparazione
DE60039998D1 (de) * 1999-10-15 2008-10-02 Daiichi Sankyo Co Ltd Pentacyclische taxan-verbindungen
IT1320107B1 (it) * 2000-11-28 2003-11-18 Indena Spa Procedimento per la preparazione di derivati tassanici.
JP2007527432A (ja) * 2004-03-05 2007-09-27 フロリダ・ステイト・ユニバーシティ・リサーチ・ファウンデイション・インコーポレイテッド C7ラクチルオキシ置換タキサン
CN1923189A (zh) * 2005-08-30 2007-03-07 孔庆忠 一种紫杉碱类抗癌药物的缓释注射剂
EP2080763A1 (en) * 2008-01-18 2009-07-22 INDENA S.p.A. Crystalline form I of ortataxel
ES2389518T3 (es) * 2008-01-18 2012-10-26 Indena S.P.A. Formas sólidas de ortataxel
CN101353333B (zh) * 2008-09-08 2010-08-11 上海大学 10-去乙酰基-9(r)-氢化-1-去氧紫杉醇类似物及其制备方法
CA2832596A1 (en) * 2011-04-07 2013-07-18 Arbor Therapeutics, LLC Taxane and abeo-taxane analogs

Also Published As

Publication number Publication date
RU2016124631A (ru) 2017-12-27
US20160340365A1 (en) 2016-11-24
AU2014352372B2 (en) 2018-08-30
KR20160087899A (ko) 2016-07-22
EP3072896A1 (en) 2016-09-28
ZA201603990B (en) 2019-04-24
EP3072896A4 (en) 2017-09-06
CN104650109B (zh) 2019-01-01
EP3072896B1 (en) 2021-01-06
CA2931366A1 (en) 2015-05-28
CN104650109A (zh) 2015-05-27
CA2931366C (en) 2019-09-24
JP2016539187A (ja) 2016-12-15
US9890175B2 (en) 2018-02-13
AU2014352372A1 (en) 2016-06-16
DK3072896T5 (da) 2021-05-31
RU2686459C1 (ru) 2019-04-26
WO2015074606A1 (zh) 2015-05-28
JP6573900B2 (ja) 2019-09-11

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