DK3043777T3 - Sublingual buprenorphinspray - Google Patents
Sublingual buprenorphinspray Download PDFInfo
- Publication number
- DK3043777T3 DK3043777T3 DK14843903.7T DK14843903T DK3043777T3 DK 3043777 T3 DK3043777 T3 DK 3043777T3 DK 14843903 T DK14843903 T DK 14843903T DK 3043777 T3 DK3043777 T3 DK 3043777T3
- Authority
- DK
- Denmark
- Prior art keywords
- buprenorphinspray
- sublingual
- sublingual buprenorphinspray
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/47—Quinolines; Isoquinolines
- A61K31/485—Morphinan derivatives, e.g. morphine, codeine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
- A61K47/10—Alcohols; Phenols; Salts thereof, e.g. glycerol; Polyethylene glycols [PEG]; Poloxamers; PEG/POE alkyl ethers
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0053—Mouth and digestive tract, i.e. intraoral and peroral administration
- A61K9/006—Oral mucosa, e.g. mucoadhesive forms, sublingual droplets; Buccal patches or films; Buccal sprays
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/04—Centrally acting analgesics, e.g. opioids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/30—Drugs for disorders of the nervous system for treating abuse or dependence
- A61P25/36—Opioid-abuse
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Epidemiology (AREA)
- Engineering & Computer Science (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Nutrition Science (AREA)
- Physiology (AREA)
- Oil, Petroleum & Natural Gas (AREA)
- Emergency Medicine (AREA)
- Addiction (AREA)
- Biomedical Technology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Neurology (AREA)
- Organic Chemistry (AREA)
- Neurosurgery (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pain & Pain Management (AREA)
- Psychiatry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicinal Preparation (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201361875837P | 2013-09-10 | 2013-09-10 | |
| PCT/US2014/052699 WO2015038327A1 (en) | 2013-09-10 | 2014-08-26 | Sublingual buprenorphine spray |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| DK3043777T3 true DK3043777T3 (da) | 2020-07-20 |
Family
ID=52625856
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DK14843903.7T DK3043777T3 (da) | 2013-09-10 | 2014-08-26 | Sublingual buprenorphinspray |
Country Status (7)
| Country | Link |
|---|---|
| US (1) | US9216175B2 (enExample) |
| EP (1) | EP3043777B1 (enExample) |
| JP (1) | JP2016529328A (enExample) |
| CA (1) | CA2923811C (enExample) |
| DK (1) | DK3043777T3 (enExample) |
| ES (1) | ES2802976T3 (enExample) |
| WO (1) | WO2015038327A1 (enExample) |
Families Citing this family (25)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CA2944512C (en) | 2014-04-04 | 2018-04-24 | Intra-Cellular Therapies, Inc. | Heterocycle fused gamma-carbolines for treatment of central nervous system disorders |
| US10617686B2 (en) * | 2014-07-08 | 2020-04-14 | Hikma Pharmaceuticals Usa Inc. | Liquid naloxone spray |
| WO2016007245A1 (en) * | 2014-07-08 | 2016-01-14 | Insys Pharma, Inc. | Sublingual naloxone spray |
| US11135155B2 (en) | 2014-07-08 | 2021-10-05 | Hikma Pharmaceuticals Usa Inc. | Liquid naloxone spray |
| US10722510B2 (en) * | 2014-07-08 | 2020-07-28 | Hikma Pharmaceuticals Usa Inc. | Liquid naloxone spray |
| EP3277283B8 (en) * | 2015-04-03 | 2021-04-28 | Benuvia Therapeutics, LLC | Sildenafil sublingual spray formulations |
| WO2016164158A1 (en) * | 2015-04-09 | 2016-10-13 | Insys Development Company, Inc. | Ketorolac sublingual spray formulations |
| JP2018531964A (ja) * | 2015-10-27 | 2018-11-01 | インシス・ディベロップメント・カンパニー・インコーポレイテッド | 液体ブプレノルフィン製剤 |
| PT3407888T (pt) | 2016-01-26 | 2021-03-19 | Intra Cellular Therapies Inc | Compostos de piridopirroloquinoxalina, suas composições e utilizações |
| SI3407889T1 (sl) | 2016-03-25 | 2021-09-30 | Intra-Cellular Therapies, Inc. | Organske spojine in njihova uporaba v zdravljenju ali preprečevanju motenj centralnega živčnega sistema |
| EP3500261A4 (en) * | 2016-08-17 | 2020-05-06 | Hikma Pharmaceuticals USA Inc. | LIQUID NALOXONE SPRAYING |
| HUE057221T2 (hu) | 2016-11-29 | 2022-04-28 | Oculis SA | Szilárd ciklodextrin komplexek készítményei szemészetileg aktív gyógyászati hatóanyag adagolásához |
| WO2018126140A1 (en) | 2016-12-29 | 2018-07-05 | Intra-Cellular Therapies, Inc. | Organic compounds |
| WO2018126143A1 (en) | 2016-12-29 | 2018-07-05 | Intra-Cellular Therapies, Inc. | Organic compounds |
| IL304026B2 (en) | 2017-03-24 | 2024-11-01 | Intra Cellular Therapies Inc | A pharmaceutical preparation containing 1-(4-fluoro-phenyl)-4-((Sa10,Rb6)-3-D2-2,2-methyl-2, 3, a10, 10, 9, b6- hexahydro-H7, H1- Pyrido[3',4',:4,5]pyrrolo[3,2,1-de]quioxalin-8-yl)-butan-1-one and its uses |
| WO2019026085A1 (en) * | 2017-08-04 | 2019-02-07 | Alkem Laboratories Ltd. | SUBLINGUAL FILM COMPOSITION |
| US20180193332A1 (en) * | 2017-10-09 | 2018-07-12 | Adapt Pharma Operations Limited | Low-temperature stable opioid antagonist solutions |
| US11980617B2 (en) | 2018-03-16 | 2024-05-14 | Intra-Cellular Therapies, Inc. | Methods of treating acute depression and/or acute anxiety |
| IL277504B1 (en) | 2018-03-23 | 2026-02-01 | Intra Cellular Therapies Inc | Deuterium-converted ((sa10,rb6)-8-(3-(4-fluorophenoxy)propyl 6b, 7, 8, 9, 10, 10a-hexahydro-1h-pyrido[3',4':4,5]pyrrolo[1,2,3-de]quinoxalin-82(h3)-one compounds, pharmaceutical composition containing them and their uses |
| US12144808B2 (en) | 2018-08-29 | 2024-11-19 | Intra-Cellular Therapies, Inc. | Compositions and methods |
| AU2019328528B2 (en) | 2018-08-31 | 2025-01-23 | Intra-Cellular Therapies, Inc. | Novel methods |
| MX2021002321A (es) | 2018-08-31 | 2021-04-28 | Intra Cellular Therapies Inc | Nuevos metodos. |
| SI3993807T1 (sl) | 2019-07-01 | 2026-04-30 | Oculis Operations Sarl | Postopek za stabiliziranje ph vodnega sestavka, ki obsega zdravilo |
| JP2022549335A (ja) | 2019-09-25 | 2022-11-24 | イントラ－セルラー・セラピーズ・インコーポレイテッド | 新規方法 |
| US12414948B2 (en) | 2022-05-18 | 2025-09-16 | Intra-Cellular Therapies, Inc. | Methods |
Family Cites Families (27)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6512010B1 (en) | 1996-07-15 | 2003-01-28 | Alza Corporation | Formulations for the administration of fluoxetine |
| US6413496B1 (en) | 1996-12-04 | 2002-07-02 | Biogland Ireland (R&D) Limited | Pharmaceutical compositions and devices for their administration |
| IT1302682B1 (it) | 1998-10-16 | 2000-09-29 | Formenti Farmaceutici Spa | Composizioni farmaceutiche orali contenenti buprenorfina |
| KR100383252B1 (ko) * | 1998-12-17 | 2003-07-16 | 주식회사 삼양사 | 부프레놀핀을함유하는경피투여조성물및이를포함하는패취 |
| AR031682A1 (es) * | 1999-11-19 | 2003-10-01 | Reckitt Benckiser Helthcare Uk | Composiciones farmaceuticas |
| WO2001097780A2 (en) | 2000-06-22 | 2001-12-27 | Pharmasol Ltd | Pharmaceutical compositions comprising an opioid analgesic |
| EP1418862A4 (en) | 2001-06-29 | 2010-06-09 | Leon J Lewandowski | INDIVIDUALIZED SEARCH THERAPY |
| US7666876B2 (en) | 2002-03-19 | 2010-02-23 | Vernalis (R&D) Limited | Buprenorphine formulations for intranasal delivery |
| US6946150B2 (en) | 2002-08-14 | 2005-09-20 | Gw Pharma Limited | Pharmaceutical formulation |
| WO2004018312A1 (en) * | 2002-08-21 | 2004-03-04 | Pharmacia Corporation | Injectable pharmaceutical suspension in a two-chamber vial |
| AU2003285934A1 (en) * | 2002-10-25 | 2004-05-25 | Euro-Celtique S.A. | Analogs and prodrugs of buprenorphine |
| WO2004071491A1 (en) | 2003-02-04 | 2004-08-26 | Chrysalis Technologies Incorporated | Aerosol formulations and aerosol delivery of buspirone, buprenorphine, triazolam, cyclobenzaprine and zolpidem |
| US20090117054A1 (en) * | 2005-03-29 | 2009-05-07 | University Of Kentucky Research Foundation | Sublingual spray for the treatment of pain |
| WO2007070632A2 (en) | 2005-12-13 | 2007-06-21 | Biodelivery Sciences International, Inc. | Abuse resistant transmucosal drug delivery device |
| AU2007208229B2 (en) * | 2006-01-25 | 2009-11-05 | Insys Therapeutics Inc. | Sublingual fentanyl spray |
| WO2007123955A2 (en) * | 2006-04-19 | 2007-11-01 | Novadel Pharma Inc. | Stable hydroalcoholic oral spray formulations and methods |
| US20100233257A1 (en) | 2006-06-09 | 2010-09-16 | Ethypharm | Low dose sublingual tablets of opioid analgesics and preparation process |
| AU2007275581B2 (en) | 2006-07-21 | 2011-09-08 | Biodelivery Sciences International, Inc. | Transmucosal delivery devices with enhanced uptake |
| EP1897543A1 (en) | 2006-08-30 | 2008-03-12 | Euro-Celtique S.A. | Buprenorphine- wafer for drug substitution therapy |
| GB2461681A (en) * | 2008-04-17 | 2010-01-13 | Pharmasol Ltd | Buprenorphine liquid spray formulation with solvent and antioxidant |
| US20090270438A1 (en) | 2006-10-18 | 2009-10-29 | Clive Booles | Novel compositions and formulations |
| GB2447014A (en) | 2007-03-01 | 2008-09-03 | Reckitt Benckiser Healthcare | Analgesic composition comprising a specific ratio of buprenorphine and naltrexone |
| AU2008282743B2 (en) * | 2007-08-02 | 2012-11-29 | Insys Therapeutics Inc. | Sublingual fentanyl spray |
| EP2254561A2 (en) | 2008-03-26 | 2010-12-01 | AllTranz Inc. | Abuse deterrent transdermal formulations of opiate agonists and agonist-antagonists |
| AU2009271271A1 (en) | 2008-06-23 | 2010-01-21 | Biodelivery Sciences International, Inc. | Multidirectional mucosal delivery devices and methods of use |
| US8475832B2 (en) * | 2009-08-07 | 2013-07-02 | Rb Pharmaceuticals Limited | Sublingual and buccal film compositions |
| JP5941038B2 (ja) * | 2010-04-02 | 2016-06-29 | ジネルバ ファーマシューティカルズ， インコーポレイティド | 経皮送達可能なオピオイドプロドラッグ、乱用抵抗性組成物及びオピオイドプロドラッグを使用する方法 |
-
2014
- 2014-08-26 EP EP14843903.7A patent/EP3043777B1/en active Active
- 2014-08-26 JP JP2016541991A patent/JP2016529328A/ja active Pending
- 2014-08-26 US US14/469,063 patent/US9216175B2/en active Active
- 2014-08-26 CA CA2923811A patent/CA2923811C/en active Active
- 2014-08-26 DK DK14843903.7T patent/DK3043777T3/da active
- 2014-08-26 WO PCT/US2014/052699 patent/WO2015038327A1/en not_active Ceased
- 2014-08-26 ES ES14843903T patent/ES2802976T3/es active Active
Also Published As
| Publication number | Publication date |
|---|---|
| WO2015038327A1 (en) | 2015-03-19 |
| JP2016529328A (ja) | 2016-09-23 |
| EP3043777B1 (en) | 2020-04-22 |
| EP3043777A1 (en) | 2016-07-20 |
| ES2802976T3 (es) | 2021-01-22 |
| CA2923811C (en) | 2021-07-27 |
| CA2923811A1 (en) | 2015-03-19 |
| EP3043777A4 (en) | 2017-08-02 |
| US20150071971A1 (en) | 2015-03-12 |
| HK1225653A1 (en) | 2017-09-15 |
| US9216175B2 (en) | 2015-12-22 |
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