DK300781A - Fremgangsmaade til fremstilling af halogenfenylpyridyllylamin-derivater - Google Patents

Fremgangsmaade til fremstilling af halogenfenylpyridyllylamin-derivater

Info

Publication number
DK300781A
DK300781A DK300781A DK300781A DK300781A DK 300781 A DK300781 A DK 300781A DK 300781 A DK300781 A DK 300781A DK 300781 A DK300781 A DK 300781A DK 300781 A DK300781 A DK 300781A
Authority
DK
Denmark
Prior art keywords
halogenphenylpyridyllylamine
derivatives
preparing
preparing halogenphenylpyridyllylamine
halogenphenylpyridyllylamine derivatives
Prior art date
Application number
DK300781A
Other languages
Danish (da)
English (en)
Inventor
T Hoegberg
T D Paulis
S B Ross
C B J Ulff
Original Assignee
Astra Laekemedel Ab
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Astra Laekemedel Ab filed Critical Astra Laekemedel Ab
Publication of DK300781A publication Critical patent/DK300781A/da

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D213/00Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/24Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with substituted hydrocarbon radicals attached to ring carbon atoms
    • C07D213/28Radicals substituted by singly-bound oxygen or sulphur atoms
    • C07D213/30Oxygen atoms
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/24Antidepressants
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D213/00Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/24Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with substituted hydrocarbon radicals attached to ring carbon atoms
    • C07D213/26Radicals substituted by halogen atoms or nitro radicals
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D213/00Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/24Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with substituted hydrocarbon radicals attached to ring carbon atoms
    • C07D213/36Radicals substituted by singly-bound nitrogen atoms
    • C07D213/38Radicals substituted by singly-bound nitrogen atoms having only hydrogen or hydrocarbon radicals attached to the substituent nitrogen atom
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D213/00Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/24Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with substituted hydrocarbon radicals attached to ring carbon atoms
    • C07D213/44Radicals substituted by doubly-bound oxygen, sulfur, or nitrogen atoms, or by two such atoms singly-bound to the same carbon atom
    • C07D213/46Oxygen atoms
    • C07D213/48Aldehydo radicals

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Psychiatry (AREA)
  • Medicinal Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pain & Pain Management (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pyridine Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
DK300781A 1979-11-16 1981-07-07 Fremgangsmaade til fremstilling af halogenfenylpyridyllylamin-derivater DK300781A (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
SE7909514A SE7909514L (sv) 1979-11-16 1979-11-16 Nya halofenyl-pyridyl-allylaminderivat
PCT/SE1980/000286 WO1981001407A1 (en) 1979-11-16 1980-11-14 Novel halophenyl-pyridyl-allylamine derivatives

Publications (1)

Publication Number Publication Date
DK300781A true DK300781A (da) 1981-07-07

Family

ID=20339337

Family Applications (1)

Application Number Title Priority Date Filing Date
DK300781A DK300781A (da) 1979-11-16 1981-07-07 Fremgangsmaade til fremstilling af halogenfenylpyridyllylamin-derivater

Country Status (17)

Country Link
US (1) US4418065A (fi)
EP (2) EP0029420A1 (fi)
JP (1) JPS56501524A (fi)
AU (1) AU538087B2 (fi)
CA (1) CA1155128A (fi)
DK (1) DK300781A (fi)
ES (5) ES8204721A1 (fi)
FI (1) FI812196L (fi)
GR (1) GR72129B (fi)
NO (1) NO812401L (fi)
NZ (1) NZ195558A (fi)
PL (3) PL129370B1 (fi)
PT (1) PT72066B (fi)
SE (1) SE7909514L (fi)
SU (4) SU1103794A3 (fi)
WO (1) WO1981001407A1 (fi)
ZA (1) ZA807102B (fi)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA1150269A (en) * 1980-11-14 1983-07-19 Carl B. J. Ulff Process for preparing 3-(4-bromophenyl)-3-(3-pyridyl)-allylamines
US4610995A (en) * 1984-07-27 1986-09-09 Coker Geoffrey G Certain 1,1-diaryl-propenyl-3-(1-pyrrolidino-2-carboxylic acids, derivatives thereof and their anti-histaminic properties
GB8814639D0 (en) * 1988-06-20 1988-07-27 Ici Plc Heterocyclic tertiary alcohol derivatives
US6288083B1 (en) 1998-09-04 2001-09-11 Millennium Pharmaceuticals, Inc. Chemokine receptor antagonists and methods of use therefor
US6503926B2 (en) 1998-09-04 2003-01-07 Millennium Pharmaceuticals, Inc. Chemokine receptor antagonists and methods of use therefor
GB0219154D0 (en) * 2002-08-16 2002-09-25 Pfizer Ltd Diaryl compounds
US6800652B2 (en) 2002-08-16 2004-10-05 Pfizer Inc. Diaryl compounds
JP6479834B2 (ja) 2013-11-05 2019-03-06 アストラゼネカ・アクチエボラーグAstrazeneca Aktiebolag Nmdaアンタゴニストプロドラッグ

Family Cites Families (22)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2676964A (en) * 1950-06-07 1954-04-27 Schering Corp 3-pyridyl propylamine antihistamine substances
DE966534C (de) * 1951-03-22 1957-08-22 Schering Corp Verfahren zur Herstellung von basisch substituierten Pyridinverbindungen
GB850298A (en) 1956-10-30 1960-10-05 Maggioni & C Societa Per Azion ª‡,ª‡[(p-chlorophenyl)-(4-pyridyl)] carbinols and method of preparing same
DE1468359A1 (de) * 1963-10-23 1968-11-28 Merck & Co Inc Verfahren zur Herstellung von Dibenzocycloheptehderivaten
US3396224A (en) * 1965-09-09 1968-08-06 Lilly Co Eli Controlling phytopathogenic fungi on plants with 3-pyridyl methane derivatives
US3423510A (en) * 1966-08-31 1969-01-21 Geigy Chem Corp 3-(p-halophenyl) - 3 - (2'-pyridyl-n-methylpropylamine for the treatment of depression
US3471505A (en) * 1967-02-01 1969-10-07 Ciba Geigy Corp 1-(alkoxyphenyl)-1-(3-pyridyl)-carbinols
US3928369A (en) * 1971-04-28 1975-12-23 Haessle Ab Compounds useful as antidepressive agents, and a process for their preparation
US3928613A (en) * 1971-04-28 1975-12-23 Haessle Ab Compounds useful as antidepressive agents
SE361663B (fi) * 1971-04-28 1973-11-12 Haessle Ab
SE373850B (fi) * 1972-11-16 1975-02-17 Haessle Ab
US4094908A (en) * 1973-08-15 1978-06-13 Richter Gedeon Vegyeszeti Gyar Rt. Alpha-substituted benzhydrol derivatives
GB1480593A (en) * 1973-11-30 1977-07-20 Kefalas As Xanthene and thioxanthene derivatives having pharmaceutical activity
US4102887A (en) * 1974-11-21 1978-07-25 Per Arvid Emil Carlsson Intermediates used in the preparation of phenyl-pyridylamine derivatives
SE388854B (sv) 1974-11-21 1979-03-26 Astra Laekemedel Ab Forfarande for framstellning av fenylpyridylaminderivat
US4186202A (en) * 1974-11-21 1980-01-29 Astra Lakemedel Aktiebolag Phenyl-pyridylamine derivatives
SE418291B (sv) * 1976-05-17 1981-05-18 Astra Laekemedel Ab 4-bromfenyl-3-pyridylderivat som mellanprodukter vid framstellning av fenylpyridylaminer
SE409706B (sv) * 1976-05-21 1979-09-03 Astra Pharma Prod Forfarande for framstellning av n,n-dimetyl-3-(4-bromfenyl)-3-3(3-pyridyl)-allylamin dihydroklorid monohydrat
SE418399B (sv) * 1976-05-21 1981-05-25 Astra Laekemedel Ab Forfarande for framstellning av n,n-dimetyl-3-(4 bromfenyl)-3-(3-pyridyl)allylamin
EP0000322B1 (en) * 1977-07-04 1982-05-05 Astra Läkemedel Aktiebolag Compounds having an anti-depressive or tranquilizing activity, pharmaceutical compositions containing them, and processes and intermediates for their preparation
SE409861B (sv) * 1977-07-04 1979-09-10 Astra Laekemedel Ab Ett nytt forfarande for framstellning av en terapeutisk aktiv pyridinforening
SE409860B (sv) * 1977-07-04 1979-09-10 Astra Laekemedel Ab En ny mellanprodukt for framstellning av terapeutiskt aktiva pyridinforeningar

Also Published As

Publication number Publication date
AU538087B2 (en) 1984-07-26
GR72129B (fi) 1983-09-16
AU6437880A (en) 1981-05-21
ES496859A0 (es) 1982-05-01
SE7909514L (sv) 1981-05-17
WO1981001407A1 (en) 1981-05-28
ES8300097A1 (es) 1982-10-01
ES8300096A1 (es) 1982-10-01
PL129369B1 (en) 1984-05-31
EP0081478A3 (en) 1984-01-04
SU1149875A3 (ru) 1985-04-07
ES8204721A1 (es) 1982-05-01
JPS56501524A (fi) 1981-10-22
ES508063A0 (es) 1982-10-01
SU1103794A3 (ru) 1984-07-15
PL129370B1 (en) 1984-05-31
FI812196L (fi) 1981-07-10
NO812401L (no) 1981-07-13
NZ195558A (en) 1984-07-06
ES508065A0 (es) 1982-10-01
ES508064A0 (es) 1982-10-01
PL227849A1 (fi) 1981-12-23
EP0081478A2 (en) 1983-06-15
PT72066B (en) 1982-09-02
PL232732A1 (fi) 1982-08-16
ES8300094A1 (es) 1982-10-01
PT72066A (en) 1980-12-01
SU1149874A3 (en) 1985-04-07
PL232731A1 (fi) 1982-08-16
ZA807102B (en) 1981-07-29
SU1138021A3 (ru) 1985-01-30
CA1155128A (en) 1983-10-11
EP0029420A1 (en) 1981-05-27
PL128457B1 (en) 1984-01-31
ES508062A0 (es) 1982-10-01
US4418065A (en) 1983-11-29
ES8300095A1 (es) 1982-10-01

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Legal Events

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ATS Application withdrawn