DK2989205T3 - Bacterial artificial chromosomes - Google Patents

Bacterial artificial chromosomes Download PDF

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Publication number
DK2989205T3
DK2989205T3 DK14724009.7T DK14724009T DK2989205T3 DK 2989205 T3 DK2989205 T3 DK 2989205T3 DK 14724009 T DK14724009 T DK 14724009T DK 2989205 T3 DK2989205 T3 DK 2989205T3
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Prior art keywords
cdna
viral
rna
bac
vaccine
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DK14724009.7T
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Danish (da)
English (en)
Inventor
Kai Dallmeier
Johan Neyts
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Univ Leuven Kath
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Publication of DK2989205T3 publication Critical patent/DK2989205T3/en

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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K39/12Viral antigens
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12Antivirals
    • A61P31/14Antivirals for RNA viruses
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09Recombinant DNA-technology
    • C12N15/63Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/67General methods for enhancing the expression
    • C12N15/69Increasing the copy number of the vector
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N7/00Viruses; Bacteriophages; Compositions thereof; Preparation or purification thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/51Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
    • A61K2039/525Virus
    • A61K2039/5254Virus avirulent or attenuated
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2770/00MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses positive-sense
    • C12N2770/00011Details
    • C12N2770/24011Flaviviridae
    • C12N2770/24111Flavivirus, e.g. yellow fever virus, dengue, JEV
    • C12N2770/24134Use of virus or viral component as vaccine, e.g. live-attenuated or inactivated virus, VLP, viral protein
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02ATECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A50/00TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
    • Y02A50/30Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Organic Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Biotechnology (AREA)
  • General Health & Medical Sciences (AREA)
  • General Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Microbiology (AREA)
  • Virology (AREA)
  • Medicinal Chemistry (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • Immunology (AREA)
  • Biophysics (AREA)
  • Public Health (AREA)
  • Plant Pathology (AREA)
  • Physics & Mathematics (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • Mycology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Peptides Or Proteins (AREA)
DK14724009.7T 2013-04-26 2014-04-25 Bacterial artificial chromosomes DK2989205T3 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GBGB1307528.8A GB201307528D0 (en) 2013-04-26 2013-04-26 Bacterial artificial chromosomes
PCT/EP2014/058459 WO2014174078A1 (en) 2013-04-26 2014-04-25 Bacterial artificial chromosomes

Publications (1)

Publication Number Publication Date
DK2989205T3 true DK2989205T3 (en) 2019-04-23

Family

ID=48626864

Family Applications (1)

Application Number Title Priority Date Filing Date
DK14724009.7T DK2989205T3 (en) 2013-04-26 2014-04-25 Bacterial artificial chromosomes

Country Status (17)

Country Link
US (2) US10076564B2 (enExample)
EP (2) EP2989205B1 (enExample)
JP (1) JP6501756B2 (enExample)
KR (1) KR102170609B1 (enExample)
CN (2) CN105229153A (enExample)
AU (1) AU2014259354B2 (enExample)
BR (1) BR112015026531B1 (enExample)
DK (1) DK2989205T3 (enExample)
ES (1) ES2718187T3 (enExample)
GB (1) GB201307528D0 (enExample)
HU (1) HUE042886T2 (enExample)
PL (1) PL2989205T3 (enExample)
PT (1) PT2989205T (enExample)
SI (1) SI2989205T1 (enExample)
TR (1) TR201904215T4 (enExample)
WO (1) WO2014174078A1 (enExample)
ZA (1) ZA201507795B (enExample)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB201716254D0 (en) 2017-10-05 2017-11-22 Univ Leuven Kath Live-attenuated flaviruses with heterologous antigens
GB201716307D0 (en) 2017-10-05 2017-11-22 Univ Leuven Kath Chimeric yellow fever zika virus strain
WO2019204654A1 (en) * 2018-04-18 2019-10-24 Utah State University Compositions and methods for zika virus characterization and vaccine development
GB201814563D0 (en) 2018-09-07 2018-10-24 Univ Leuven Kath Chimeric flavivirus lyssavirus vaccines
MX2021012424A (es) 2019-04-10 2022-02-10 Univ Leuven Kath Virus quimérico de zika-encefalitis japonesa.
BR112022004378A2 (pt) 2019-09-13 2022-06-07 Univ Leuven Kath Vacinas para vírus lassa
WO2021048003A1 (en) 2019-09-13 2021-03-18 Katholieke Universiteit Leuven Chimeric filovirus vaccines
MX2022003627A (es) * 2019-09-25 2022-07-21 Univ Leuven Kath Vectores grandes y metodos para produccion con alto rendimiento.
AU2021225362A1 (en) * 2020-02-27 2022-09-15 Katholieke Universiteit Leuven Coronavirus vaccines
WO2025012350A1 (en) * 2023-07-11 2025-01-16 Virovet Nv Vectors expressing attenuated rna virus of the family arteriviridae and uses thereof
WO2025171062A1 (en) * 2024-02-06 2025-08-14 The Regents Of The University Of California iMODULON GENE CLUSTERS AND METHODS TO IDENTIFY AND USE SAME

Family Cites Families (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5665600A (en) 1991-09-18 1997-09-09 Research Corporation Technologies, Inc. Pichia pastoris linear plasmids and DNA fragments thereof
US5866404A (en) 1995-12-06 1999-02-02 Yale University Yeast-bacteria shuttle vector
US6962708B1 (en) * 1997-02-28 2005-11-08 Acambis, Inc. Chimeric flavivirus vaccines
US5874259A (en) * 1997-11-21 1999-02-23 Wisconsin Alumni Research Foundation Conditionally amplifiable BAC vector
WO2000034497A2 (en) 1998-12-09 2000-06-15 The General Hospital Corporation Enhanced packaging of herpes virus amplicons and generation of recombinant virus vectors
ES2170622B1 (es) 1999-12-03 2004-05-16 Consejo Superior De Investigaciones Cientificas Clones y vectores infectivos derivados de coronavirus y sus aplicaciones.
GB2372991B (en) * 2001-03-09 2004-11-17 Fiocruz Fundacao Oswaldo Cruz Flavivirus expression vector
US6472177B1 (en) 2001-04-23 2002-10-29 Wisconsin Alumni Research Foundation Expression vector with dual control of replication and transcription
US6864087B2 (en) * 2001-07-31 2005-03-08 Wisconsin Alumni Research Foundation Method for converting single-copy BAC vectors to conditional high-copy pBAC/oriHC vectors
US20050106733A1 (en) 2001-12-25 2005-05-19 Kenzo Takada Double-stranded cyclic dna capable of proliferating as a bacterial e coli chromosome
WO2004033633A2 (en) 2002-10-04 2004-04-22 Embiosis Pharmaceuticals Compatible host/vector systems for expression of dna
US20070036827A1 (en) 2003-10-29 2007-02-15 The University Of Queensland West nile virus vaccine
US20050214838A1 (en) 2004-03-10 2005-09-29 Waclaw Szybalski Methods for mapping and sequencing nucleic acids
WO2009053988A1 (en) 2007-10-25 2009-04-30 Ramot At Tel-Aviv University Ltd. Production of bac vectors carrying viral genomes
CN101864442A (zh) 2010-05-19 2010-10-20 江苏省农业科学院 重组火鸡疱疹病毒细菌人工染色体转移载体

Also Published As

Publication number Publication date
EP3540065A1 (en) 2019-09-18
SI2989205T1 (sl) 2019-05-31
AU2014259354B2 (en) 2020-02-27
ES2718187T3 (es) 2019-06-28
GB201307528D0 (en) 2013-06-12
EP2989205A1 (en) 2016-03-02
US20160206723A1 (en) 2016-07-21
CN105229153A (zh) 2016-01-06
US10076564B2 (en) 2018-09-18
BR112015026531A2 (enExample) 2017-09-05
WO2014174078A1 (en) 2014-10-30
CN120249337A (zh) 2025-07-04
EP2989205B1 (en) 2019-01-02
KR102170609B1 (ko) 2020-10-28
HUE042886T2 (hu) 2019-07-29
JP2016518132A (ja) 2016-06-23
TR201904215T4 (tr) 2019-04-22
PL2989205T3 (pl) 2019-06-28
ZA201507795B (en) 2019-07-31
AU2014259354A1 (en) 2015-11-05
BR112015026531B1 (pt) 2023-02-07
KR20160003032A (ko) 2016-01-08
US20190111125A1 (en) 2019-04-18
JP6501756B2 (ja) 2019-04-17
PT2989205T (pt) 2019-04-23

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